Click here to switch to the map view.

The map label for this gene is ureC [H]

Identifier: 146338144

GI number: 146338144

Start: 1108190

End: 1109905

Strand: Direct

Name: ureC [H]

Synonym: BRADO1041

Alternate gene names: 146338144

Gene position: 1108190-1109905 (Clockwise)

Preceding gene: 146338143

Following gene: 146338145

Centisome position: 14.86

GC content: 63.75

Gene sequence:

>1716_bases
ATGTCCGTCAAGATCAAGCGTTCCGTCTACGCCGACATGTTCGGCCCGACCACCGGCGACAAGGTGCGGCTCGCCGACAC
TGATCTCATCATCGAGGTCGAGAAGGACTTCACCGTCTATGGCGAGGAGGTGAAGTTCGGCGGTGGCAAGGTGATCCGCG
ACGGCATGGGCCAGTCGCAGGCGACCAACAAGCAGGGCGCGGCCGACACGGTCATCACCAACGCCCTGATTGTCGATCAC
TGGGGTGTCGTGAAGGCCGACGTCGCGATCAAGGACGGCATGATCAGTGCAATCGGCAAGGCCGGCAATCCCGACATCCA
GCCGGGCGTGACCATCGTGATCGGCCCGGGCACCGACGTGATTGCGGGCGAGGGCAAGATCCTCACCGCCGGCGGCTTCG
ACAGCCACATTCACTTCATCTGTCCGCAGCAGATCGAGCACGCGCTGATGAGTGGCGTCACTTCGCTGCTGGGCGGCGGC
ACCGGCCCGTCGCACGGCACCTTCGCCACCACCTGCACGCCGGGTCCGTGGCACATCGGCCGGATGATGCAATCGTTCGA
TGCCTTCCCGGTCAATCTCGGCATCTCTGGTAAGGGTAACGCATCGCGTCCCGCGGCACTGGTCGAGATGGTGAAGGCCG
GCGCCTGCGCGCTGAAGCTGCATGAGGATTGGGGCACGACACCAGCCGCGATCGACAATTGTCTGTCGGTCGCCGACGAT
CACGACATCCAGGTCATGCTGCACTCGGATACGCTGAACGAGTCCGGCTTCGTCGAGGACACGATCAAGGCCTTCAAGGG
CCGCACCATCCATGCGTTCCATACCGAAGGCGCTGGCGGCGGCCACGCCCCTGACATCATCAAAGTGGCGGGCCTGAAGA
ACGTGCTGCCGTCGTCGACCAACCCAACGCGGCCGTTCACGCGCAACACCATCGACGAGCATCTCGACATGCTGATGGTG
TGCCATCATCTGGACCCGTCCATCGCCGAGGACCTCGCCTTTGCCGAGAGCCGCATCCGCAAGGAGACGATCGCGGCCGA
GGACATCCTGCACGATCTCGGCGCGCTGTCGATGATGTCGTCAGACTCGCAGGCGATGGGCCGGCTCGGCGAGGTCATCA
TCCGGACCTGGCAGACCGCCGACAAGATGAAGAAGCAGCGCGGCGCCTTGCCGCAGGACAAGGGCAAGGACAACGACAAT
TTCCGCGTCAAGCGCTACATCGCCAAATACACGATCAATCCGGCCATCGCGCATGGCGTGTCGAAGCTGATCGGCTCGGT
CGAGAAGGGCAAGCTCGCCGACCTCGTGCTGTGGTCGCCGGCGTTCTTCGGCGTCAAGCCGGACTGCGTCATCAAGGGCG
GCACCATCGTCGCCGCCCCGATGGGAGATCCGAACGCCTCGATTCCGACGCCGCAGCCGGTGCATTACCAGCCGATGTTC
GGCGCCTTTGGCAAGTCGCTGACGGCGTCCTCGGTGATCTTCACCTCCAAGGCGGCGGTTGCCGGCGGCCTGGCGCGCAA
GCTCGGCCTGTCCAAGAAGCTCTATGCGGTGCAGAACACCCGCGGCAGGATCTCGAAGAAGAGCATGATCCACAACGATG
CCACGCCGAACATCGAGGTCGATCCCGAGACCTATGAGGTGCGCGCAGACGGCGAATTGCTCACCTGCGAGCCCGCCGAG
GTGCTGCCCATGGCGCAGCGCTATTTCATGTTCTAA

Upstream 100 bases:

>100_bases
AAGCCTGGTCTCGAGAACGTCGCCAAGTTTCAATCGATTTGCGCACGCCCGAAATGAGCGGTGCGCTATAAAAATTGAGA
GCTAGAGGCTGGAGCACGAA

Downstream 100 bases:

>100_bases
GCTTCTCCCGGTACACAAAACCAGAAACGTACCGGGAGGACTGCCTCGTGATCTATGTCGTCGCCACCTTGACCATCAAG
CCCGAAACGCGTGCCGAATT

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha [H]

Number of amino acids: Translated: 571; Mature: 570

Protein sequence:

>571_residues
MSVKIKRSVYADMFGPTTGDKVRLADTDLIIEVEKDFTVYGEEVKFGGGKVIRDGMGQSQATNKQGAADTVITNALIVDH
WGVVKADVAIKDGMISAIGKAGNPDIQPGVTIVIGPGTDVIAGEGKILTAGGFDSHIHFICPQQIEHALMSGVTSLLGGG
TGPSHGTFATTCTPGPWHIGRMMQSFDAFPVNLGISGKGNASRPAALVEMVKAGACALKLHEDWGTTPAAIDNCLSVADD
HDIQVMLHSDTLNESGFVEDTIKAFKGRTIHAFHTEGAGGGHAPDIIKVAGLKNVLPSSTNPTRPFTRNTIDEHLDMLMV
CHHLDPSIAEDLAFAESRIRKETIAAEDILHDLGALSMMSSDSQAMGRLGEVIIRTWQTADKMKKQRGALPQDKGKDNDN
FRVKRYIAKYTINPAIAHGVSKLIGSVEKGKLADLVLWSPAFFGVKPDCVIKGGTIVAAPMGDPNASIPTPQPVHYQPMF
GAFGKSLTASSVIFTSKAAVAGGLARKLGLSKKLYAVQNTRGRISKKSMIHNDATPNIEVDPETYEVRADGELLTCEPAE
VLPMAQRYFMF

Sequences:

>Translated_571_residues
MSVKIKRSVYADMFGPTTGDKVRLADTDLIIEVEKDFTVYGEEVKFGGGKVIRDGMGQSQATNKQGAADTVITNALIVDH
WGVVKADVAIKDGMISAIGKAGNPDIQPGVTIVIGPGTDVIAGEGKILTAGGFDSHIHFICPQQIEHALMSGVTSLLGGG
TGPSHGTFATTCTPGPWHIGRMMQSFDAFPVNLGISGKGNASRPAALVEMVKAGACALKLHEDWGTTPAAIDNCLSVADD
HDIQVMLHSDTLNESGFVEDTIKAFKGRTIHAFHTEGAGGGHAPDIIKVAGLKNVLPSSTNPTRPFTRNTIDEHLDMLMV
CHHLDPSIAEDLAFAESRIRKETIAAEDILHDLGALSMMSSDSQAMGRLGEVIIRTWQTADKMKKQRGALPQDKGKDNDN
FRVKRYIAKYTINPAIAHGVSKLIGSVEKGKLADLVLWSPAFFGVKPDCVIKGGTIVAAPMGDPNASIPTPQPVHYQPMF
GAFGKSLTASSVIFTSKAAVAGGLARKLGLSKKLYAVQNTRGRISKKSMIHNDATPNIEVDPETYEVRADGELLTCEPAE
VLPMAQRYFMF
>Mature_570_residues
SVKIKRSVYADMFGPTTGDKVRLADTDLIIEVEKDFTVYGEEVKFGGGKVIRDGMGQSQATNKQGAADTVITNALIVDHW
GVVKADVAIKDGMISAIGKAGNPDIQPGVTIVIGPGTDVIAGEGKILTAGGFDSHIHFICPQQIEHALMSGVTSLLGGGT
GPSHGTFATTCTPGPWHIGRMMQSFDAFPVNLGISGKGNASRPAALVEMVKAGACALKLHEDWGTTPAAIDNCLSVADDH
DIQVMLHSDTLNESGFVEDTIKAFKGRTIHAFHTEGAGGGHAPDIIKVAGLKNVLPSSTNPTRPFTRNTIDEHLDMLMVC
HHLDPSIAEDLAFAESRIRKETIAAEDILHDLGALSMMSSDSQAMGRLGEVIIRTWQTADKMKKQRGALPQDKGKDNDNF
RVKRYIAKYTINPAIAHGVSKLIGSVEKGKLADLVLWSPAFFGVKPDCVIKGGTIVAAPMGDPNASIPTPQPVHYQPMFG
AFGKSLTASSVIFTSKAAVAGGLARKLGLSKKLYAVQNTRGRISKKSMIHNDATPNIEVDPETYEVRADGELLTCEPAEV
LPMAQRYFMF

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950 [H]

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha [H]

EC number: =3.5.1.5 [H]

Molecular weight: Translated: 60934; Mature: 60802

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS00145 UREASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKIKRSVYADMFGPTTGDKVRLADTDLIIEVEKDFTVYGEEVKFGGGKVIRDGMGQSQ
CCEEECHHHHHHHCCCCCCCEEEEECCEEEEEEECCCEEECCEEEECCCEEEECCCCCCC
ATNKQGAADTVITNALIVDHWGVVKADVAIKDGMISAIGKAGNPDIQPGVTIVIGPGTDV
CCCCCCCHHHHHHHEEEEECCCEEEECEEECCCHHHHHCCCCCCCCCCCEEEEECCCCCE
IAGEGKILTAGGFDSHIHFICPQQIEHALMSGVTSLLGGGTGPSHGTFATTCTPGPWHIG
EECCCEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHH
RMMQSFDAFPVNLGISGKGNASRPAALVEMVKAGACALKLHEDWGTTPAAIDNCLSVADD
HHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCC
HDIQVMLHSDTLNESGFVEDTIKAFKGRTIHAFHTEGAGGGHAPDIIKVAGLKNVLPSST
CCEEEEEECCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEECCHHHHCCCCC
NPTRPFTRNTIDEHLDMLMVCHHLDPSIAEDLAFAESRIRKETIAAEDILHDLGALSMMS
CCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SDSQAMGRLGEVIIRTWQTADKMKKQRGALPQDKGKDNDNFRVKRYIAKYTINPAIAHGV
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEEHHHCCCHHHHHHH
SKLIGSVEKGKLADLVLWSPAFFGVKPDCVIKGGTIVAAPMGDPNASIPTPQPVHYQPMF
HHHHCCCCCCCEEEEEEECCHHCCCCCCEEEECCEEEEECCCCCCCCCCCCCCCCCCCHH
GAFGKSLTASSVIFTSKAAVAGGLARKLGLSKKLYAVQNTRGRISKKSMIHNDATPNIEV
HHHCCCCCCCCEEEECHHHHHHHHHHHHCCCHHEEEEECCCCCCHHHHHHCCCCCCCEEE
DPETYEVRADGELLTCEPAEVLPMAQRYFMF
CCCEEEEEECCCEEEECCHHHHHHHHHHHCC
>Mature Secondary Structure 
SVKIKRSVYADMFGPTTGDKVRLADTDLIIEVEKDFTVYGEEVKFGGGKVIRDGMGQSQ
CEEECHHHHHHHCCCCCCCEEEEECCEEEEEEECCCEEECCEEEECCCEEEECCCCCCC
ATNKQGAADTVITNALIVDHWGVVKADVAIKDGMISAIGKAGNPDIQPGVTIVIGPGTDV
CCCCCCCHHHHHHHEEEEECCCEEEECEEECCCHHHHHCCCCCCCCCCCEEEEECCCCCE
IAGEGKILTAGGFDSHIHFICPQQIEHALMSGVTSLLGGGTGPSHGTFATTCTPGPWHIG
EECCCEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHH
RMMQSFDAFPVNLGISGKGNASRPAALVEMVKAGACALKLHEDWGTTPAAIDNCLSVADD
HHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCC
HDIQVMLHSDTLNESGFVEDTIKAFKGRTIHAFHTEGAGGGHAPDIIKVAGLKNVLPSST
CCEEEEEECCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEECCHHHHCCCCC
NPTRPFTRNTIDEHLDMLMVCHHLDPSIAEDLAFAESRIRKETIAAEDILHDLGALSMMS
CCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SDSQAMGRLGEVIIRTWQTADKMKKQRGALPQDKGKDNDNFRVKRYIAKYTINPAIAHGV
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEEHHHCCCHHHHHHH
SKLIGSVEKGKLADLVLWSPAFFGVKPDCVIKGGTIVAAPMGDPNASIPTPQPVHYQPMF
HHHHCCCCCCCEEEEEEECCHHCCCCCCEEEECCEEEEECCCCCCCCCCCCCCCCCCCHH
GAFGKSLTASSVIFTSKAAVAGGLARKLGLSKKLYAVQNTRGRISKKSMIHNDATPNIEV
HHHCCCCCCCCEEEECHHHHHHHHHHHHCCCHHEEEEECCCCCCHHHHHHCCCCCCCEEE
DPETYEVRADGELLTCEPAEVLPMAQRYFMF
CCCEEEEEECCCEEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]