Click here to switch to the map view.

The map label for this gene is livH [H]

Identifier: 146338135

GI number: 146338135

Start: 1101207

End: 1102769

Strand: Direct

Name: livH [H]

Synonym: BRADO1032

Alternate gene names: 146338135

Gene position: 1101207-1102769 (Clockwise)

Preceding gene: 146338134

Following gene: 146338136

Centisome position: 14.77

GC content: 66.22

Gene sequence:

>1563_bases
TTGATCGTCGCGACCGCTCCGGCGTTTGCCGCCAGCTTCGAAGAGTCGGTCGCCAAATTCGCAAATGACGATTTCTCCGA
CACCGACGATGCGGTGGGCGAGATCGCCGTGTCCGGCAATCCGCTGGCCTATCCGATCATCAGCGCGCTGCAGGACGAGC
GGCTGATGTTCGATGCCGAGACCAAGAAGGTCTATGTCAAGCAGACCGACGGCAAGATCATCGATGCCGCGACCGGCGCG
GCCGTCGACAAGCTGCCCGACAATGCCGCGGCGGTGAGCCTCAACAACCGCCTGCGCCGCACCGTGGACGCCGCGCTCGG
CGGCCTGACGCTGCTGTCGCCGGACACCAATACGCGCCTGACCGCTGCGAAATCGGTGTTCAAGTCGCATGACGAGGCGA
CGCTGTCGACCGTAGAGTCGGCGCTCGCCAAGGAGACCAACCGCACGGTCAAGCAGGCGCTGGCCGAGGCGCGTGCCGCG
ATCCTGCTGTTCAAGTCCGACGCCAGCGAGGTCGACAAGCTCGACGCCGTCGCCACCATCAGGTCGCGCGGCGACCAGGA
GGCGCTGGCGCTGCTGACCGAGATCAGCGGCGGCGACCAGCCCGCCAACGTCGCCAGGGCGGCGGCGAGCGCGATCTCAT
CGATCCAGGGCTCGCTTGCTATCTGGTCCGGCGTGCAGAACGCCTGGTACGGCCTGTCGCTCGGCTCGGTGCTGCTGCTG
GCCGCCATCGGCCTCGCCATCACCTTCGGTGTGATGGGCGTCATCAACATGGCCCATGGCGAGATGGTGATGCTCGGCGC
CTACACCACCTTCGTCGTGCAGGAGGTCATCCGCACGCGCTATCCCGCGCTGTTCGACTACTCGCTTCTGATCGCCGCAC
CGCTCGCCTTCCTGGTGGCCGGCGCGATCGGCGTGCTGATCGAGCGCACCATCATCCGCTTCCTCTATGGCCGTCCGTTG
GAGACGCTGCTCGCCACCTGGGGCCTGTCGCTGATCCTGCAGCAGGCGGTCCGCTCCGCGTTCGGTCCGACCAACCGTGA
GGTCGGCAATCCCTCCTGGATGAGCGGCGCGTTCGAGCTGGGGCAGATTACCATCACCTACAATCGGCTCTGGATCCTCT
GCTTTACCATGGCCGTGTTCGCGATCCTGCTGGCGATGCTGCGCTACACGGCGCTCGGCCTTGAGATGCGCGCAGTGACG
CAGAACCGGCGCATGGCGGCCTCGATGGGCATCGCGACGTCGCGGGTCGATGCGCTGACCTTCGGCCTCGGCTCCGGCAT
CGCCGGGATTGCCGGGGTGGCGCTGTCGCAGATCGACAATGTCAGCCCGAACCTCGGTCAGAGCTACATCATCGACTCCT
TCATGGTCGTGGTGTTCGGCGGCGTCGGCAATCTCTGGGGTACGCTGGTCGGCGCCTTCACGCTCGGCATCGCCAACAAG
TTCCTGGAGCCGGTCGCCGGCGCGGTGCTCGGCAAGATCGCGATCCTGGTGCTGATCATCCTTTTCATTCAGAAGCGCCC
GCGCGGGCTGTTCGCGCTCAAGGGCCGGGCGGTGGAAGCATGA

Upstream 100 bases:

>100_bases
AGGCGGCGACCTCCGCCGCCTTCTCTCTTCCTCCTGCCGGGGTGGTCCAGTGCCTGCCATTGTTCTCGCGCTTGTGCGCG
GTCTTCTTCTGTCCATTGCC

Downstream 100 bases:

>100_bases
TGCCGCATCTGCTGACCCGCTCGCTCGACCGCGGCGCGTCGATCTTTCTCCTGATCGTCGCCGCCTGCGGCATCCTGATC
CCGCTGTCCAACCTGCTGCT

Product: branched chain amino acid ABC transporter permease

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein H [H]

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MIVATAPAFAASFEESVAKFANDDFSDTDDAVGEIAVSGNPLAYPIISALQDERLMFDAETKKVYVKQTDGKIIDAATGA
AVDKLPDNAAAVSLNNRLRRTVDAALGGLTLLSPDTNTRLTAAKSVFKSHDEATLSTVESALAKETNRTVKQALAEARAA
ILLFKSDASEVDKLDAVATIRSRGDQEALALLTEISGGDQPANVARAAASAISSIQGSLAIWSGVQNAWYGLSLGSVLLL
AAIGLAITFGVMGVINMAHGEMVMLGAYTTFVVQEVIRTRYPALFDYSLLIAAPLAFLVAGAIGVLIERTIIRFLYGRPL
ETLLATWGLSLILQQAVRSAFGPTNREVGNPSWMSGAFELGQITITYNRLWILCFTMAVFAILLAMLRYTALGLEMRAVT
QNRRMAASMGIATSRVDALTFGLGSGIAGIAGVALSQIDNVSPNLGQSYIIDSFMVVVFGGVGNLWGTLVGAFTLGIANK
FLEPVAGAVLGKIAILVLIILFIQKRPRGLFALKGRAVEA

Sequences:

>Translated_520_residues
MIVATAPAFAASFEESVAKFANDDFSDTDDAVGEIAVSGNPLAYPIISALQDERLMFDAETKKVYVKQTDGKIIDAATGA
AVDKLPDNAAAVSLNNRLRRTVDAALGGLTLLSPDTNTRLTAAKSVFKSHDEATLSTVESALAKETNRTVKQALAEARAA
ILLFKSDASEVDKLDAVATIRSRGDQEALALLTEISGGDQPANVARAAASAISSIQGSLAIWSGVQNAWYGLSLGSVLLL
AAIGLAITFGVMGVINMAHGEMVMLGAYTTFVVQEVIRTRYPALFDYSLLIAAPLAFLVAGAIGVLIERTIIRFLYGRPL
ETLLATWGLSLILQQAVRSAFGPTNREVGNPSWMSGAFELGQITITYNRLWILCFTMAVFAILLAMLRYTALGLEMRAVT
QNRRMAASMGIATSRVDALTFGLGSGIAGIAGVALSQIDNVSPNLGQSYIIDSFMVVVFGGVGNLWGTLVGAFTLGIANK
FLEPVAGAVLGKIAILVLIILFIQKRPRGLFALKGRAVEA
>Mature_520_residues
MIVATAPAFAASFEESVAKFANDDFSDTDDAVGEIAVSGNPLAYPIISALQDERLMFDAETKKVYVKQTDGKIIDAATGA
AVDKLPDNAAAVSLNNRLRRTVDAALGGLTLLSPDTNTRLTAAKSVFKSHDEATLSTVESALAKETNRTVKQALAEARAA
ILLFKSDASEVDKLDAVATIRSRGDQEALALLTEISGGDQPANVARAAASAISSIQGSLAIWSGVQNAWYGLSLGSVLLL
AAIGLAITFGVMGVINMAHGEMVMLGAYTTFVVQEVIRTRYPALFDYSLLIAAPLAFLVAGAIGVLIERTIIRFLYGRPL
ETLLATWGLSLILQQAVRSAFGPTNREVGNPSWMSGAFELGQITITYNRLWILCFTMAVFAILLAMLRYTALGLEMRAVT
QNRRMAASMGIATSRVDALTFGLGSGIAGIAGVALSQIDNVSPNLGQSYIIDSFMVVVFGGVGNLWGTLVGAFTLGIANK
FLEPVAGAVLGKIAILVLIILFIQKRPRGLFALKGRAVEA

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=297, Percent_Identity=32.6599326599327, Blast_Score=102, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 54957; Mature: 54957

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVATAPAFAASFEESVAKFANDDFSDTDDAVGEIAVSGNPLAYPIISALQDERLMFDAE
CEEECCHHHHHHHHHHHHHHCCCCCCCCCHHHHEEEECCCCCHHHHHHHHHHCHHEEECC
TKKVYVKQTDGKIIDAATGAAVDKLPDNAAAVSLNNRLRRTVDAALGGLTLLSPDTNTRL
CCEEEEEECCCCEEECCCCCHHHCCCCCCEEEEHHHHHHHHHHHHHCCCEEECCCCCCHH
TAAKSVFKSHDEATLSTVESALAKETNRTVKQALAEARAAILLFKSDASEVDKLDAVATI
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHH
RSRGDQEALALLTEISGGDQPANVARAAASAISSIQGSLAIWSGVQNAWYGLSLGSVLLL
HHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
AAIGLAITFGVMGVINMAHGEMVMLGAYTTFVVQEVIRTRYPALFDYSLLIAAPLAFLVA
HHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
GAIGVLIERTIIRFLYGRPLETLLATWGLSLILQQAVRSAFGPTNREVGNPSWMSGAFEL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCEEE
GQITITYNRLWILCFTMAVFAILLAMLRYTALGLEMRAVTQNRRMAASMGIATSRVDALT
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHH
FGLGSGIAGIAGVALSQIDNVSPNLGQSYIIDSFMVVVFGGVGNLWGTLVGAFTLGIANK
HHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
FLEPVAGAVLGKIAILVLIILFIQKRPRGLFALKGRAVEA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCC
>Mature Secondary Structure
MIVATAPAFAASFEESVAKFANDDFSDTDDAVGEIAVSGNPLAYPIISALQDERLMFDAE
CEEECCHHHHHHHHHHHHHHCCCCCCCCCHHHHEEEECCCCCHHHHHHHHHHCHHEEECC
TKKVYVKQTDGKIIDAATGAAVDKLPDNAAAVSLNNRLRRTVDAALGGLTLLSPDTNTRL
CCEEEEEECCCCEEECCCCCHHHCCCCCCEEEEHHHHHHHHHHHHHCCCEEECCCCCCHH
TAAKSVFKSHDEATLSTVESALAKETNRTVKQALAEARAAILLFKSDASEVDKLDAVATI
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHH
RSRGDQEALALLTEISGGDQPANVARAAASAISSIQGSLAIWSGVQNAWYGLSLGSVLLL
HHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
AAIGLAITFGVMGVINMAHGEMVMLGAYTTFVVQEVIRTRYPALFDYSLLIAAPLAFLVA
HHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
GAIGVLIERTIIRFLYGRPLETLLATWGLSLILQQAVRSAFGPTNREVGNPSWMSGAFEL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCEEE
GQITITYNRLWILCFTMAVFAILLAMLRYTALGLEMRAVTQNRRMAASMGIATSRVDALT
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHH
FGLGSGIAGIAGVALSQIDNVSPNLGQSYIIDSFMVVVFGGVGNLWGTLVGAFTLGIANK
HHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
FLEPVAGAVLGKIAILVLIILFIQKRPRGLFALKGRAVEA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]