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The map label for this gene is yngJ [H]

Identifier: 146338041

GI number: 146338041

Start: 998547

End: 999674

Strand: Direct

Name: yngJ [H]

Synonym: BRADO0934

Alternate gene names: 146338041

Gene position: 998547-999674 (Clockwise)

Preceding gene: 146338040

Following gene: 146338042

Centisome position: 13.39

GC content: 67.46

Gene sequence:

>1128_bases
ATGAACTTCGATTTTTCCGACGACCAGAAGCAGCTGCGGGACCAGGCGCGGAAATTCCTCGCCGAGAAGTGCCCGCCGAA
AGCCGTGCGCGTCGTGCTCGACGGCAAGGAGCCGTATGACCGCGCGCTGTGGAAGGGCTTTGCCGAGATGGGGTTCCTCG
GCGTGGCCATTCCGGAAGAATATGGCGGCGCGGGCGCTGGCCATCTCGAGCTGTGCGTGCTCGCCGAGGAGGTGGGCCGC
GCGCTGGCGCCGGTGCCGTTCTCGTCGACCGTCTATCTCGCGGCCGAGGCTTTGATGCTGGCCGGCAGCGACGCGCAGAA
GCAGGCCTGGCTGCCGAAGATCGCAAACGGCGAGACGATCGGCACCCTTGCGCTGTTCGAGGGCACCGGCAATCCTTCGC
CGAAGGCGATCAAGCTCGAAGCTGGCAACGGCTTGCTCAACGGCACCAAGAAGCCGGTCGCCGATGGCGCCATCGCCGAT
CTCATCATCGTGGCGGCGCGCACGGCCTCAACCGGCCGCGACAGCGACATCTCGCTGTTCCTGGTCGACACCAAGGCCGG
CGGCGTGGAGGCGAAGGCGCTGACCAATCTCGATCCGACCCGCGGCCAGGCCGAGCTTACCTTTGCGAATTGCAAGGCCG
AGCCGCTCGGCGCGGCCGGCGAGGGCTGGAGCATCCTCACCCAGGTGCTCGACCGCGCCGCCGTGCTGACCGCGTTCGAG
CAGGTCGGCGGCTCCGATCGCGCGCTGGAAATGGGCCGCGACTACGCGCTCGACCGCATCGCCTTCGGCCGGCCGATCGG
CTCGTTCCAGGCGGTCAAGCACATGCTGGCCGACATGTATGTCTCGGCGACCTTGGCGCGCTCCAACGCCTATTACGGCG
CCTGGGCGCTCTCGACCAATGCGCCGGAATTGCCGGAGGCCGCGGCCTCGGCGCGCATCAGCGCGACGCAGGCCTATCAG
CATTGCGGCAAGAACAACATCCAGGTCCATGGCGGCATGGGCTTCACCTGGGAGTTCGACTGTCACATGTACTACCGCCG
CGCCAACGCGCTCGCGCTCGGGCTGGGCAGCCTGTCCTACTGGGAAGACCAGCTGATCGACCGCATGCGCAAGCGCAACG
CGGCGTGA

Upstream 100 bases:

>100_bases
GCCGAAGCCCGTTCCGGGCCCATCGAATCGCCGGTGGCTATGGGTCCCGGCTTTCGCCGGGACGACCACCAAGAGACTTT
CCAACAATAGAGTTGATCCC

Downstream 100 bases:

>100_bases
GGCAAGCCCGTCATTCCGGGGCGCTCGCGCGCGCCGAAATGGCTACGCCATTTTGCGCGGAGCGAGCGAACCCGGAATCC
AGAGGTTATCTCGTCGAGAT

Product: putative acyl-CoA dehydrogenase

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MNFDFSDDQKQLRDQARKFLAEKCPPKAVRVVLDGKEPYDRALWKGFAEMGFLGVAIPEEYGGAGAGHLELCVLAEEVGR
ALAPVPFSSTVYLAAEALMLAGSDAQKQAWLPKIANGETIGTLALFEGTGNPSPKAIKLEAGNGLLNGTKKPVADGAIAD
LIIVAARTASTGRDSDISLFLVDTKAGGVEAKALTNLDPTRGQAELTFANCKAEPLGAAGEGWSILTQVLDRAAVLTAFE
QVGGSDRALEMGRDYALDRIAFGRPIGSFQAVKHMLADMYVSATLARSNAYYGAWALSTNAPELPEAAASARISATQAYQ
HCGKNNIQVHGGMGFTWEFDCHMYYRRANALALGLGSLSYWEDQLIDRMRKRNAA

Sequences:

>Translated_375_residues
MNFDFSDDQKQLRDQARKFLAEKCPPKAVRVVLDGKEPYDRALWKGFAEMGFLGVAIPEEYGGAGAGHLELCVLAEEVGR
ALAPVPFSSTVYLAAEALMLAGSDAQKQAWLPKIANGETIGTLALFEGTGNPSPKAIKLEAGNGLLNGTKKPVADGAIAD
LIIVAARTASTGRDSDISLFLVDTKAGGVEAKALTNLDPTRGQAELTFANCKAEPLGAAGEGWSILTQVLDRAAVLTAFE
QVGGSDRALEMGRDYALDRIAFGRPIGSFQAVKHMLADMYVSATLARSNAYYGAWALSTNAPELPEAAASARISATQAYQ
HCGKNNIQVHGGMGFTWEFDCHMYYRRANALALGLGSLSYWEDQLIDRMRKRNAA
>Mature_375_residues
MNFDFSDDQKQLRDQARKFLAEKCPPKAVRVVLDGKEPYDRALWKGFAEMGFLGVAIPEEYGGAGAGHLELCVLAEEVGR
ALAPVPFSSTVYLAAEALMLAGSDAQKQAWLPKIANGETIGTLALFEGTGNPSPKAIKLEAGNGLLNGTKKPVADGAIAD
LIIVAARTASTGRDSDISLFLVDTKAGGVEAKALTNLDPTRGQAELTFANCKAEPLGAAGEGWSILTQVLDRAAVLTAFE
QVGGSDRALEMGRDYALDRIAFGRPIGSFQAVKHMLADMYVSATLARSNAYYGAWALSTNAPELPEAAASARISATQAYQ
HCGKNNIQVHGGMGFTWEFDCHMYYRRANALALGLGSLSYWEDQLIDRMRKRNAA

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=366, Percent_Identity=32.2404371584699, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI4557233, Length=360, Percent_Identity=30, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI226958414, Length=334, Percent_Identity=31.7365269461078, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI4501857, Length=354, Percent_Identity=26.5536723163842, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI4501859, Length=355, Percent_Identity=25.9154929577465, Blast_Score=111, Evalue=9e-25,
Organism=Homo sapiens, GI21361497, Length=383, Percent_Identity=27.154046997389, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI76496475, Length=359, Percent_Identity=26.1838440111421, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI4557235, Length=361, Percent_Identity=25.7617728531856, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI187960098, Length=372, Percent_Identity=25.2688172043011, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI4557231, Length=372, Percent_Identity=25.2688172043011, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI7656849, Length=359, Percent_Identity=26.1838440111421, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI7669494, Length=295, Percent_Identity=28.4745762711864, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI4503943, Length=295, Percent_Identity=28.4745762711864, Blast_Score=92, Evalue=8e-19,
Organism=Escherichia coli, GI1786223, Length=354, Percent_Identity=23.728813559322, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87081958, Length=367, Percent_Identity=23.9782016348774, Blast_Score=82, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17538396, Length=366, Percent_Identity=29.5081967213115, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17534899, Length=408, Percent_Identity=27.4509803921569, Blast_Score=114, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17570075, Length=373, Percent_Identity=25.4691689008043, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17569725, Length=392, Percent_Identity=26.530612244898, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17508101, Length=357, Percent_Identity=26.3305322128852, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71985184, Length=359, Percent_Identity=26.4623955431755, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17506239, Length=346, Percent_Identity=23.9884393063584, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17534353, Length=293, Percent_Identity=25.5972696245734, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71985192, Length=334, Percent_Identity=25.4491017964072, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17533517, Length=353, Percent_Identity=23.5127478753541, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71990804, Length=278, Percent_Identity=24.4604316546763, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17505929, Length=354, Percent_Identity=23.4463276836158, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17562446, Length=266, Percent_Identity=25.9398496240602, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356377, Length=357, Percent_Identity=30.2521008403361, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24646207, Length=356, Percent_Identity=29.4943820224719, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI21355753, Length=369, Percent_Identity=28.7262872628726, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24666513, Length=382, Percent_Identity=25.6544502617801, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24660351, Length=372, Percent_Identity=25.5376344086022, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281363737, Length=320, Percent_Identity=24.6875, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI19920834, Length=290, Percent_Identity=28.6206896551724, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 40111; Mature: 40111

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFDFSDDQKQLRDQARKFLAEKCPPKAVRVVLDGKEPYDRALWKGFAEMGFLGVAIPEE
CCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCEEEEECCHH
YGGAGAGHLELCVLAEEVGRALAPVPFSSTVYLAAEALMLAGSDAQKQAWLPKIANGETI
HCCCCCCHHHHEEEHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCEE
GTLALFEGTGNPSPKAIKLEAGNGLLNGTKKPVADGAIADLIIVAARTASTGRDSDISLF
EEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEE
LVDTKAGGVEAKALTNLDPTRGQAELTFANCKAEPLGAAGEGWSILTQVLDRAAVLTAFE
EEECCCCCEEHHEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
QVGGSDRALEMGRDYALDRIAFGRPIGSFQAVKHMLADMYVSATLARSNAYYGAWALSTN
HHCCCCHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
APELPEAAASARISATQAYQHCGKNNIQVHGGMGFTWEFDCHMYYRRANALALGLGSLSY
CCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEECCEEEEEHHCEEEEECCCHHH
WEDQLIDRMRKRNAA
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MNFDFSDDQKQLRDQARKFLAEKCPPKAVRVVLDGKEPYDRALWKGFAEMGFLGVAIPEE
CCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCEEEEECCHH
YGGAGAGHLELCVLAEEVGRALAPVPFSSTVYLAAEALMLAGSDAQKQAWLPKIANGETI
HCCCCCCHHHHEEEHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCEE
GTLALFEGTGNPSPKAIKLEAGNGLLNGTKKPVADGAIADLIIVAARTASTGRDSDISLF
EEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEE
LVDTKAGGVEAKALTNLDPTRGQAELTFANCKAEPLGAAGEGWSILTQVLDRAAVLTAFE
EEECCCCCEEHHEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
QVGGSDRALEMGRDYALDRIAFGRPIGSFQAVKHMLADMYVSATLARSNAYYGAWALSTN
HHCCCCHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
APELPEAAASARISATQAYQHCGKNNIQVHGGMGFTWEFDCHMYYRRANALALGLGSLSY
CCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEECCEEEEEHHCEEEEECCCHHH
WEDQLIDRMRKRNAA
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]