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The map label for this gene is fabG [C]

Identifier: 146338025

GI number: 146338025

Start: 979451

End: 980152

Strand: Reverse

Name: fabG [C]

Synonym: BRADO0918

Alternate gene names: 146338025

Gene position: 980152-979451 (Counterclockwise)

Preceding gene: 146338026

Following gene: 146338022

Centisome position: 13.14

GC content: 70.09

Gene sequence:

>702_bases
ATGGACATCCCAGCCTACAAGATCGCCTTGATCGTCGGCGCCGGCGAAGGGCTCTCCGCCTCGCTGGCGCGGCTGTTCGC
GCGCGAGAAGATCCGCGTCGCGCTGGCCGCGCGCAAGACCGAGAAGCTCGGCGCGATCTGCAGCGAGACCGGCGCCCGTG
CCTATCCGTGCGACGCCACCAATCCGGAGGAGGTCGAGCGGCTGTTCGGCCTGGTCTCGCGCGAGATCGGCGAGCCCGAT
CTCGTCGTCTACAATGCCAGCGCCCGGGCGCGCGGGCCGCTCACCGATCTCGTCCCGGCCGATGTGCAGAACGCGATCGC
CGTCAGCGCGTTCGGCGGCTTCCTGGTGGCGCAGCAGGCGGCGCAGCGCATGCTGCCGAACAAGCACGGCGCCATCCTGT
TCACCGGCGCCTCGGCCAGCGTGAAGGGATACGCCCAATCGGCGCCATTCGCGATGGGCAAGTTCGCGCTGCGCGGCCTG
GCCCAGAGCATGGCCCGCGAGCTGTCGCCGCAAGGCATCCACGTCGCGCATTTCGTCATCGACGGCGGCATCAGGAGCGC
GGCGCGGCAGGAGCCGGCCGAGCGGCCGGATTCGATGCTCGATCCGGATGCGATCGCCGCCAGCTATTGGAGCGTGCTGC
AGCAGCCGCGCAGCGCCTGGAGCTGGGAGATGGAGCTGCGTCCCTGGGTGGAGACGTTCTGA

Upstream 100 bases:

>100_bases
TCAGGCAAAATTGTGGGGATGGGTGGTGGGCAGTTGGCCTTGGCTGCACTAGCTTGAGGGCCGCGGACGCTTTGCCAAGC
ATCTTTCAAGGACATGCCTC

Downstream 100 bases:

>100_bases
GGGTTGATGTTCTGTAGCATGGGCAAAGACAAGCCGCGGGACGCGCAGCATCACGCGGGGCGACGTGCCCACCATTGGCG
CCGCGCGCTGGCTGAGGGAC

Product: putative 3-oxoacyl-[acyl-carrier-protein] reductase

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MDIPAYKIALIVGAGEGLSASLARLFAREKIRVALAARKTEKLGAICSETGARAYPCDATNPEEVERLFGLVSREIGEPD
LVVYNASARARGPLTDLVPADVQNAIAVSAFGGFLVAQQAAQRMLPNKHGAILFTGASASVKGYAQSAPFAMGKFALRGL
AQSMARELSPQGIHVAHFVIDGGIRSAARQEPAERPDSMLDPDAIAASYWSVLQQPRSAWSWEMELRPWVETF

Sequences:

>Translated_233_residues
MDIPAYKIALIVGAGEGLSASLARLFAREKIRVALAARKTEKLGAICSETGARAYPCDATNPEEVERLFGLVSREIGEPD
LVVYNASARARGPLTDLVPADVQNAIAVSAFGGFLVAQQAAQRMLPNKHGAILFTGASASVKGYAQSAPFAMGKFALRGL
AQSMARELSPQGIHVAHFVIDGGIRSAARQEPAERPDSMLDPDAIAASYWSVLQQPRSAWSWEMELRPWVETF
>Mature_233_residues
MDIPAYKIALIVGAGEGLSASLARLFAREKIRVALAARKTEKLGAICSETGARAYPCDATNPEEVERLFGLVSREIGEPD
LVVYNASARARGPLTDLVPADVQNAIAVSAFGGFLVAQQAAQRMLPNKHGAILFTGASASVKGYAQSAPFAMGKFALRGL
AQSMARELSPQGIHVAHFVIDGGIRSAARQEPAERPDSMLDPDAIAASYWSVLQQPRSAWSWEMELRPWVETF

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI210032110, Length=171, Percent_Identity=28.6549707602339, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI40254992, Length=171, Percent_Identity=23.9766081871345, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=180, Percent_Identity=27.2222222222222, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789057, Length=213, Percent_Identity=26.2910798122066, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787526, Length=224, Percent_Identity=28.125, Blast_Score=62, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322067, Length=191, Percent_Identity=25.130890052356, Blast_Score=66, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28571387, Length=249, Percent_Identity=24.4979919678715, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 24996; Mature: 24996

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIPAYKIALIVGAGEGLSASLARLFAREKIRVALAARKTEKLGAICSETGARAYPCDAT
CCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NPEEVERLFGLVSREIGEPDLVVYNASARARGPLTDLVPADVQNAIAVSAFGGFLVAQQA
CHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AQRMLPNKHGAILFTGASASVKGYAQSAPFAMGKFALRGLAQSMARELSPQGIHVAHFVI
HHHHCCCCCCEEEEECCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEE
DGGIRSAARQEPAERPDSMLDPDAIAASYWSVLQQPRSAWSWEMELRPWVETF
CCCHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCHHHCC
>Mature Secondary Structure
MDIPAYKIALIVGAGEGLSASLARLFAREKIRVALAARKTEKLGAICSETGARAYPCDAT
CCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NPEEVERLFGLVSREIGEPDLVVYNASARARGPLTDLVPADVQNAIAVSAFGGFLVAQQA
CHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AQRMLPNKHGAILFTGASASVKGYAQSAPFAMGKFALRGLAQSMARELSPQGIHVAHFVI
HHHHCCCCCCEEEEECCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEE
DGGIRSAARQEPAERPDSMLDPDAIAASYWSVLQQPRSAWSWEMELRPWVETF
CCCHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]