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The map label for this gene is xerC [H]

Identifier: 146337558

GI number: 146337558

Start: 421199

End: 422182

Strand: Reverse

Name: xerC [H]

Synonym: BRADO0412

Alternate gene names: 146337558

Gene position: 422182-421199 (Counterclockwise)

Preceding gene: 146337560

Following gene: 146337557

Centisome position: 5.66

GC content: 70.33

Gene sequence:

>984_bases
ATGGCAAAGACGGCAGAAGCGACTGACAACGCGCCCGACCTCCCCGACCTCATCGGTGCCGACGACGGCGTCGTACGCGC
CATGACGCAGTGGCTGGCGCATTTGCGCAGCGAACGGCGGCTGTCGCCGAAGACGGTCGAGGCCTATGCGCGCGACCTCC
GGCAATGCCTGCAATTCCTCTGCACGCATTGGGGCGAGCCGGTCACGCTCCCGCGCTTCGCCGCGCTGGAGGCCTCCGAC
ATCCGCGCTTTCATGGCGATGCGCCGCGCCGACGACATCGCCGGCCGATCCCTGATGCGGACCTTGGCGGGCCTGCGCTC
GTTCGGCCGCTTCCTGGAGCGCGAGGGCCAGGGCAAGGTCGGCGCACTTGCAGGCGTGCGCGCGCCAAAGATCGCCAAGA
GCCTGCCGAAGCCGCTGCCGATGGACTCCGCCAAGCGTCTCACGGACGCCGACGAGCGCGCCGGCGAGTCACGCGAGACC
TGGGTGCTGGCGCGCGACGCCGCCGTAATGGCCCTGCTCTATGGCTCAGGCCTGCGCATCTCCGAGGCGCTCGGCCTGAA
GCGGCGCGAGGTGCCGCGCCCCGGCGAAGGCGACGTGCTGATCGTGACCGGCAAGGGCAACAAGACCCGCATGGTGCCGG
TGCTGCAGAACGTGCTTGCGCTGATCGATGAATACGCACGTCTGTGCCCCTACCCGCTGCCCGCCGAGGGCCCGATGTTT
CTCGGCGCCAAGGGCGGTCCGCTGAGCCCGCGCATCATCCAGCTGGCGATGGAGCGGCTGCGCGGCGCGCTCGGCCTGCC
GGACAGCGCCACGCCGCACGCGCTGCGCCATTCCTTCGCGACGCATCTGTTGTCGCGCGGCGGCGATTTGCGCGCGATCC
AGGAGCTGCTCGGGCACGCCTCGCTGTCGACCACACAGGTCTACACCGGCATCGATTCGGAGCGGCTGCTGCAGGTCTAC
GCGTCGGCGCATCCGCGGCGGTGA

Upstream 100 bases:

>100_bases
TCGAAGCCACCCTCTCCCACAAGAGGAGAGGGTACACCGCGCATGCCGCTGAATGCGTTCGACGTCATCAGGACGATGAG
TCGGCAGGTGTGCGTGATCG

Downstream 100 bases:

>100_bases
CACCGTTCCGTCACATCCTTTCCCTTGCGCGACCACCGAGCTTCCGGCAATCGTTCCCTCGCTTGATCCGGAGGGGAACA
GATGAGCGCACATGAGAGCA

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MAKTAEATDNAPDLPDLIGADDGVVRAMTQWLAHLRSERRLSPKTVEAYARDLRQCLQFLCTHWGEPVTLPRFAALEASD
IRAFMAMRRADDIAGRSLMRTLAGLRSFGRFLEREGQGKVGALAGVRAPKIAKSLPKPLPMDSAKRLTDADERAGESRET
WVLARDAAVMALLYGSGLRISEALGLKRREVPRPGEGDVLIVTGKGNKTRMVPVLQNVLALIDEYARLCPYPLPAEGPMF
LGAKGGPLSPRIIQLAMERLRGALGLPDSATPHALRHSFATHLLSRGGDLRAIQELLGHASLSTTQVYTGIDSERLLQVY
ASAHPRR

Sequences:

>Translated_327_residues
MAKTAEATDNAPDLPDLIGADDGVVRAMTQWLAHLRSERRLSPKTVEAYARDLRQCLQFLCTHWGEPVTLPRFAALEASD
IRAFMAMRRADDIAGRSLMRTLAGLRSFGRFLEREGQGKVGALAGVRAPKIAKSLPKPLPMDSAKRLTDADERAGESRET
WVLARDAAVMALLYGSGLRISEALGLKRREVPRPGEGDVLIVTGKGNKTRMVPVLQNVLALIDEYARLCPYPLPAEGPMF
LGAKGGPLSPRIIQLAMERLRGALGLPDSATPHALRHSFATHLLSRGGDLRAIQELLGHASLSTTQVYTGIDSERLLQVY
ASAHPRR
>Mature_326_residues
AKTAEATDNAPDLPDLIGADDGVVRAMTQWLAHLRSERRLSPKTVEAYARDLRQCLQFLCTHWGEPVTLPRFAALEASDI
RAFMAMRRADDIAGRSLMRTLAGLRSFGRFLEREGQGKVGALAGVRAPKIAKSLPKPLPMDSAKRLTDADERAGESRETW
VLARDAAVMALLYGSGLRISEALGLKRREVPRPGEGDVLIVTGKGNKTRMVPVLQNVLALIDEYARLCPYPLPAEGPMFL
GAKGGPLSPRIIQLAMERLRGALGLPDSATPHALRHSFATHLLSRGGDLRAIQELLGHASLSTTQVYTGIDSERLLQVYA
SAHPRR

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=299, Percent_Identity=35.7859531772575, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1789261, Length=307, Percent_Identity=33.2247557003257, Blast_Score=135, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 35666; Mature: 35535

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTAEATDNAPDLPDLIGADDGVVRAMTQWLAHLRSERRLSPKTVEAYARDLRQCLQFL
CCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
CTHWGEPVTLPRFAALEASDIRAFMAMRRADDIAGRSLMRTLAGLRSFGRFLEREGQGKV
HHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
GALAGVRAPKIAKSLPKPLPMDSAKRLTDADERAGESRETWVLARDAAVMALLYGSGLRI
HHHHCCCCHHHHHHCCCCCCCCHHHHHCCCHHHCCCCCHHEEEEHHHHHHHHHHCCCCCH
SEALGLKRREVPRPGEGDVLIVTGKGNKTRMVPVLQNVLALIDEYARLCPYPLPAEGPMF
HHHHCCHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
LGAKGGPLSPRIIQLAMERLRGALGLPDSATPHALRHSFATHLLSRGGDLRAIQELLGHA
ECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
SLSTTQVYTGIDSERLLQVYASAHPRR
CCCHHHHCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AKTAEATDNAPDLPDLIGADDGVVRAMTQWLAHLRSERRLSPKTVEAYARDLRQCLQFL
CCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
CTHWGEPVTLPRFAALEASDIRAFMAMRRADDIAGRSLMRTLAGLRSFGRFLEREGQGKV
HHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
GALAGVRAPKIAKSLPKPLPMDSAKRLTDADERAGESRETWVLARDAAVMALLYGSGLRI
HHHHCCCCHHHHHHCCCCCCCCHHHHHCCCHHHCCCCCHHEEEEHHHHHHHHHHCCCCCH
SEALGLKRREVPRPGEGDVLIVTGKGNKTRMVPVLQNVLALIDEYARLCPYPLPAEGPMF
HHHHCCHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
LGAKGGPLSPRIIQLAMERLRGALGLPDSATPHALRHSFATHLLSRGGDLRAIQELLGHA
ECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
SLSTTQVYTGIDSERLLQVYASAHPRR
CCCHHHHCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]