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The map label for this gene is rprX [H]

Identifier: 146302696

GI number: 146302696

Start: 6005881

End: 6007149

Strand: Direct

Name: rprX [H]

Synonym: Fjoh_4969

Alternate gene names: 146302696

Gene position: 6005881-6007149 (Clockwise)

Preceding gene: 146302693

Following gene: 146302697

Centisome position: 98.51

GC content: 29.0

Gene sequence:

>1269_bases
TTGAAAATAAATAAACTCAATAGTATTATAGTTCTAGGACTTGTCGCCATAATAAGTATTTTGGTGGCACAATTGCTTTG
GACTAAAGAAGCTTTTACAATTGAACAAAAAAAGCTGAGTCAAAAAGCACATATTGCACTTCTGGAAGTTGCAAAAAAAT
TATATGAAGGAACCAATCATGAACTTCCGGCACAAAATCCTGTGCAAAAAATTGCCAACGATTATTATATAGTAAATGTC
GACAATGAGTTTGAGCCTGATATTCTAGAATTTTATCTCCTGACTGAATTCAAAAAAATGAATATCACGACAGATTTTGA
ATACGCTATGTACAATTGCCAGAGCGACGAAATGATTTATGGTGATTACATTTCTTTATCGCACAAAAAAAAATCTGAGT
GTAAAAAAACTGTCTATTTTCCTAAACATAAAAATCTGGTTTATTATTTCGCAGTGCGTTTTCCTAACGAAACCACTTAT
TTATTCAGTTCAATGCGGTTTTGGTTTATCCTTTCGATTGCTTTAATCTTGATTTTGTTGATTTACGTTTATTCGATTTT
TACTCTTTTACAGCAAAAAAAATATTCAGAATTACAGCGTGATTTTATCAATAATATGACGCATGAGTTTAAAACTCCTT
TGTCTTCTATTTTAATTGCTTCAAAATATTTAAGCGAACAAAGCCCGATTAAAGATGATAAGAAACTGTACACTTATACA
GAAATCATTATTAATCAAAGCCACAAACTAAATCATCATGTAGAAAAAATTCTAAACGTTGCCAAATCAGATCATACTCC
GTTAGAATTAAAAAAAGAAAGTGTTATAATTGTTCCGATAATCGAAGAAGCTATCGAAAATATCCAGTTAAAATGCCCTG
AAGCCGTTATTCAAATTGAAAGTTCATCAAAAGAATATATATTAGAAACTGATGTTTTTCATTTTGCTAATTTGATTTAC
AACCTTTTAGATAATGCGATAAAATACTGCAATAAAAAACCTGAGATTACGATTAGAATTTCAGAAGAAAATTCGACTTT
AAAATTAGAATTTATTGATAATGGAATTGGTATTTCTTCTAAAAAAATATCCTTTATATTTGATAAATTTTATCGCGTTC
AAAACGAAAAGAGTAATGAAGTAAATGGTTTTGGACTTGGATTATACTATGTTAAAGAAATCTGCAGCCTGCAGAACTGG
AAAATAAAAGCTGAAAATAATTCTGAAAACGGAGTTACTATAACTTTGTTAATTCCTTATAAAAAATGA

Upstream 100 bases:

>100_bases
GAATCGCTGTTAACCGCTTTCAAATGTTTGTTAACGACTTGTTAATCGCTTTTTTTAAGTATATTTTTGATTAATATTAC
ACTTTCTAAAGTCTGTTTTC

Downstream 100 bases:

>100_bases
AAAACTTCAAAATACTTTACACAGAAGACGATGAAACTCTGGCATTTTTAACCAAAGATAATCTGGAACAGAATAATTAT
GAAGTTATTCACTGCACCAA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MKINKLNSIIVLGLVAIISILVAQLLWTKEAFTIEQKKLSQKAHIALLEVAKKLYEGTNHELPAQNPVQKIANDYYIVNV
DNEFEPDILEFYLLTEFKKMNITTDFEYAMYNCQSDEMIYGDYISLSHKKKSECKKTVYFPKHKNLVYYFAVRFPNETTY
LFSSMRFWFILSIALILILLIYVYSIFTLLQQKKYSELQRDFINNMTHEFKTPLSSILIASKYLSEQSPIKDDKKLYTYT
EIIINQSHKLNHHVEKILNVAKSDHTPLELKKESVIIVPIIEEAIENIQLKCPEAVIQIESSSKEYILETDVFHFANLIY
NLLDNAIKYCNKKPEITIRISEENSTLKLEFIDNGIGISSKKISFIFDKFYRVQNEKSNEVNGFGLGLYYVKEICSLQNW
KIKAENNSENGVTITLLIPYKK

Sequences:

>Translated_422_residues
MKINKLNSIIVLGLVAIISILVAQLLWTKEAFTIEQKKLSQKAHIALLEVAKKLYEGTNHELPAQNPVQKIANDYYIVNV
DNEFEPDILEFYLLTEFKKMNITTDFEYAMYNCQSDEMIYGDYISLSHKKKSECKKTVYFPKHKNLVYYFAVRFPNETTY
LFSSMRFWFILSIALILILLIYVYSIFTLLQQKKYSELQRDFINNMTHEFKTPLSSILIASKYLSEQSPIKDDKKLYTYT
EIIINQSHKLNHHVEKILNVAKSDHTPLELKKESVIIVPIIEEAIENIQLKCPEAVIQIESSSKEYILETDVFHFANLIY
NLLDNAIKYCNKKPEITIRISEENSTLKLEFIDNGIGISSKKISFIFDKFYRVQNEKSNEVNGFGLGLYYVKEICSLQNW
KIKAENNSENGVTITLLIPYKK
>Mature_422_residues
MKINKLNSIIVLGLVAIISILVAQLLWTKEAFTIEQKKLSQKAHIALLEVAKKLYEGTNHELPAQNPVQKIANDYYIVNV
DNEFEPDILEFYLLTEFKKMNITTDFEYAMYNCQSDEMIYGDYISLSHKKKSECKKTVYFPKHKNLVYYFAVRFPNETTY
LFSSMRFWFILSIALILILLIYVYSIFTLLQQKKYSELQRDFINNMTHEFKTPLSSILIASKYLSEQSPIKDDKKLYTYT
EIIINQSHKLNHHVEKILNVAKSDHTPLELKKESVIIVPIIEEAIENIQLKCPEAVIQIESSSKEYILETDVFHFANLIY
NLLDNAIKYCNKKPEITIRISEENSTLKLEFIDNGIGISSKKISFIFDKFYRVQNEKSNEVNGFGLGLYYVKEICSLQNW
KIKAENNSENGVTITLLIPYKK

Specific function: Member of the two-component regulatory system rprX/rprY. May activate rprY by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=233, Percent_Identity=24.8927038626609, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786912, Length=232, Percent_Identity=25.8620689655172, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790861, Length=234, Percent_Identity=27.7777777777778, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786600, Length=286, Percent_Identity=24.1258741258741, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790436, Length=266, Percent_Identity=23.3082706766917, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1787894, Length=221, Percent_Identity=23.0769230769231, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082128, Length=241, Percent_Identity=22.8215767634855, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790346, Length=227, Percent_Identity=21.5859030837004, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI48994928, Length=229, Percent_Identity=23.5807860262009, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788713, Length=230, Percent_Identity=23.9130434782609, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49200; Mature: 49200

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKINKLNSIIVLGLVAIISILVAQLLWTKEAFTIEQKKLSQKAHIALLEVAKKLYEGTNH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ELPAQNPVQKIANDYYIVNVDNEFEPDILEFYLLTEFKKMNITTDFEYAMYNCQSDEMIY
CCCCCCHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHEECCCCCCEEE
GDYISLSHKKKSECKKTVYFPKHKNLVYYFAVRFPNETTYLFSSMRFWFILSIALILILL
ECEEECCCCCHHHHHHCEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
IYVYSIFTLLQQKKYSELQRDFINNMTHEFKTPLSSILIASKYLSEQSPIKDDKKLYTYT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCHHHHHHH
EIIINQSHKLNHHVEKILNVAKSDHTPLELKKESVIIVPIIEEAIENIQLKCPEAVIQIE
HHHHCCCCHHHHHHHHHHHHHCCCCCCCEECCCCEEEEEEHHHHHHCCEEECCHHEEEEE
SSSKEYILETDVFHFANLIYNLLDNAIKYCNKKPEITIRISEENSTLKLEFIDNGIGISS
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEECCCCCCCC
KKISFIFDKFYRVQNEKSNEVNGFGLGLYYVKEICSLQNWKIKAENNSENGVTITLLIPY
CHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEEEC
KK
CC
>Mature Secondary Structure
MKINKLNSIIVLGLVAIISILVAQLLWTKEAFTIEQKKLSQKAHIALLEVAKKLYEGTNH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ELPAQNPVQKIANDYYIVNVDNEFEPDILEFYLLTEFKKMNITTDFEYAMYNCQSDEMIY
CCCCCCHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHEECCCCCCEEE
GDYISLSHKKKSECKKTVYFPKHKNLVYYFAVRFPNETTYLFSSMRFWFILSIALILILL
ECEEECCCCCHHHHHHCEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
IYVYSIFTLLQQKKYSELQRDFINNMTHEFKTPLSSILIASKYLSEQSPIKDDKKLYTYT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCHHHHHHH
EIIINQSHKLNHHVEKILNVAKSDHTPLELKKESVIIVPIIEEAIENIQLKCPEAVIQIE
HHHHCCCCHHHHHHHHHHHHHCCCCCCCEECCCCEEEEEEHHHHHHCCEEECCHHEEEEE
SSSKEYILETDVFHFANLIYNLLDNAIKYCNKKPEITIRISEENSTLKLEFIDNGIGISS
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEECCCCCCCC
KKISFIFDKFYRVQNEKSNEVNGFGLGLYYVKEICSLQNWKIKAENNSENGVTITLLIPY
CHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEEEC
KK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8469117 [H]