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The map label for this gene is exo I [H]

Identifier: 146302535

GI number: 146302535

Start: 5811971

End: 5814475

Strand: Reverse

Name: exo I [H]

Synonym: Fjoh_4808

Alternate gene names: 146302535

Gene position: 5814475-5811971 (Counterclockwise)

Preceding gene: 146302536

Following gene: 146302534

Centisome position: 95.37

GC content: 36.65

Gene sequence:

>2505_bases
ATGAAAAGAAGTGTATTGCTGATAGCCATTTTTCTGAGTTCTTTAAGTACCATACAAGCACAGAAACTAGATATAATTCC
TAAACCCGTAAAAGTTGAACAAAATGAAGGCGTATTTATTATTCCGTCATCAGTACAAATTATTGTAGACAAAAAAGCAG
AAAAAAGTGCTGAATATATTAAGAGTTCTTTTTCGAAATACACAGGGATTAACGCAATCGTTTCTATTGGAAATAAACAC
AAAAAAAATACCATAGCATTTTTGGTCGATGAAAAAATGAACCTTCCTAATGATGGTTATAAATTGAATATCAACAAAAA
AGGAATTTTAGTAAAAGGGAAATCTGCAAACGGAGTTTTAAACGGTCTGCAGACTTTATTGCAAATTTCTTCTGCAAAAG
ACATTAAAAAAGGAAATATCCCATTTGTAAAAATAGAAGATTATCCTCGTTTTGAATGGCGCGGTATGATGCTCGACTGT
TCAAGACAGTTTTTTGATAAACAAACCGTTAAAAATTATATTGACTGGCTGGCGGCGCACAAAATGAATGTTTTTCACTG
GCATTTAACCGATGATAACGGCTGGAGAATTGAAATCAAATCGATGCCTGATTTAACTTTAAAAGGTGCCTGGAGAGGTC
CGGGAGAAGTTTTACTGCCATCTTATGGTTCAGGAGACAAACGTTACGGAGGTTTTTATACGCAGGAACATATCAAAGAA
GTAGTGGCGTATGCTGCTAATCGCGGCATATCAGTTATGCCCGAAATTGAAATTCCGGGGCATTCGCGTGCCGTAACCGC
TTCGTATCCGGAAGTGGGCTGTGCGATAACACAGGAACTTAAAAGTGTTCAGGGTGAAGTAAAAAATGTTTGGTGTGTGG
GTCGTGAAGAAAATTATGTTCTTCTGGATTCAATCATTAGAGAAGTTTCGGGACTTTTTCCTTTTGAATATATTCATGTT
GCCGGAGATGAAGTCAATCGTGCCAACTGGGAAAATTGCCCAAAATGTCAGGCTTTGATGGTGAAAGAAGGTTTTACAGA
TAGTTTTCAGCTTCAAAATTATTTCTTTAGAAGAGTTCAAAAAATTGTAGATAAATACCATAAAAAAACAGATGGCTGGA
ACGAAATTTTAAAAGGTGGAGAAATTGATCCAAATACTTTGATTTCTGCCTGGCAGGGAATTAGTTACGGAATTGAATCG
GCAAAGAAAGGATACCAGACTATTATGATGCCGGGGCAATATACGTATTTTGATATGGCACAGTCTGAAACAGAACGCGG
TCATCGCTGGGCGGCTATTACAGATACGAAAAGAGCCTATTCATTTGAGCCAATTCCTACTGATGATTTAACACCAGAAC
AGCAAAAAAATATAATAGGTGTTCAGGGCGCTTTGTGGAGCGAATATCTGGATCGTCCAGCCAGAATTATGGAATACCAA
AGTTATCCAAGAATCAGCGCTTTATCTGAAATTGGCTGGTCTAAAAAAGAAGATAAAAACTGGGAAGATTTCTACGGAAG
ATTAACACACAGCCATTTACAGCGTTTGGCTGATATGGGAATTGCTTTTAGGGATTTTCCGCCAGCCGCAATTTATCAAA
ATGGCACGATTACCGTAACACCGCCTTACGAAGGTGCAGTTGTACGTTATGATGCACAAGGTAATGAACCAACAAGACAA
TCGGCTTTGTATACAAAACCAATTCAAACGAAGGATTATGAACATTATATGTTCCGTACTTTTTTTAATGAAGATGTGGC
AAGTCCGTCGGTAAAAGTAGAAAAACTGCCTGTTGCGGTTTGGAATACTTCAAAAGCAGAAGTTTTGAATATTTCTGAAA
ATATTTCAGAGCATGTAGACAAAAATGGAATTTGGTATTTAACTTTTACTCCTGATGCAGATGCGAGTGCCAACGGAGTT
GTAAAAACAGTTTCTCTTTATGAAAATGATAAACTGATACAGAGTTTTCCGGAAGAAAAAATGCTGAAATCAAAACCTCG
CCTGCGATTTGTAATTGAAAATTACAATGAAAAAAATACGTATCGTTTAGACTTTACGGTAGAAAATAAAGAAGCAAAAG
AATCAGCAGCAAAAGTAAATTTCAATTGTTCGCCTTATTTAGAGCCGGAAGTAAAAGTAACATCATCGATGGCTGAAAAT
CCTAAATTTCCGATTTCGAATTTAGAAGATTATAATGTTGAAACTTACTTGCGTACAGATATTGCGTGTGCAAATGGCGA
CTGGATTTTATACACTTTTACAAATCCTGTAACTTCTTCTAAAATTGATGTGTTAACCGGAATTCCGCATCACCCGAGGT
TCATTGTCAATAACGGTTATGTAGAATATTCGTATAACGGAATCGATTTTATAAAAGGAGATGCTTTTGATTATGGCAAT
GCATCGATTTATCCAAAACAGCCTGTAAAAGCAGTAAAAATTGTCATTACAGGAACCAACAACGAACCTCTTATGGCAGG
ACAGGACATAAGAATTAATCCGTAG

Upstream 100 bases:

>100_bases
TGCTGATTTGGAGAATTATATCTACGCCGTTTCCGCTTTAAGTCAGACCCAGACAGAAAGCGCTCCAATAGAATTTTCAA
TAAAATAAAAAATAAAAGCC

Downstream 100 bases:

>100_bases
AATATGAAAAAGATAACGGCAGGAATCATATTAATTTCCATGACCTTTTTAGGAATAAATGCTTATTCCCAGAAAAAATC
AAAGAAATCTTTTGATGTAA

Product: beta-N-acetylhexosaminidase

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 834; Mature: 834

Protein sequence:

>834_residues
MKRSVLLIAIFLSSLSTIQAQKLDIIPKPVKVEQNEGVFIIPSSVQIIVDKKAEKSAEYIKSSFSKYTGINAIVSIGNKH
KKNTIAFLVDEKMNLPNDGYKLNINKKGILVKGKSANGVLNGLQTLLQISSAKDIKKGNIPFVKIEDYPRFEWRGMMLDC
SRQFFDKQTVKNYIDWLAAHKMNVFHWHLTDDNGWRIEIKSMPDLTLKGAWRGPGEVLLPSYGSGDKRYGGFYTQEHIKE
VVAYAANRGISVMPEIEIPGHSRAVTASYPEVGCAITQELKSVQGEVKNVWCVGREENYVLLDSIIREVSGLFPFEYIHV
AGDEVNRANWENCPKCQALMVKEGFTDSFQLQNYFFRRVQKIVDKYHKKTDGWNEILKGGEIDPNTLISAWQGISYGIES
AKKGYQTIMMPGQYTYFDMAQSETERGHRWAAITDTKRAYSFEPIPTDDLTPEQQKNIIGVQGALWSEYLDRPARIMEYQ
SYPRISALSEIGWSKKEDKNWEDFYGRLTHSHLQRLADMGIAFRDFPPAAIYQNGTITVTPPYEGAVVRYDAQGNEPTRQ
SALYTKPIQTKDYEHYMFRTFFNEDVASPSVKVEKLPVAVWNTSKAEVLNISENISEHVDKNGIWYLTFTPDADASANGV
VKTVSLYENDKLIQSFPEEKMLKSKPRLRFVIENYNEKNTYRLDFTVENKEAKESAAKVNFNCSPYLEPEVKVTSSMAEN
PKFPISNLEDYNVETYLRTDIACANGDWILYTFTNPVTSSKIDVLTGIPHHPRFIVNNGYVEYSYNGIDFIKGDAFDYGN
ASIYPKQPVKAVKIVITGTNNEPLMAGQDIRINP

Sequences:

>Translated_834_residues
MKRSVLLIAIFLSSLSTIQAQKLDIIPKPVKVEQNEGVFIIPSSVQIIVDKKAEKSAEYIKSSFSKYTGINAIVSIGNKH
KKNTIAFLVDEKMNLPNDGYKLNINKKGILVKGKSANGVLNGLQTLLQISSAKDIKKGNIPFVKIEDYPRFEWRGMMLDC
SRQFFDKQTVKNYIDWLAAHKMNVFHWHLTDDNGWRIEIKSMPDLTLKGAWRGPGEVLLPSYGSGDKRYGGFYTQEHIKE
VVAYAANRGISVMPEIEIPGHSRAVTASYPEVGCAITQELKSVQGEVKNVWCVGREENYVLLDSIIREVSGLFPFEYIHV
AGDEVNRANWENCPKCQALMVKEGFTDSFQLQNYFFRRVQKIVDKYHKKTDGWNEILKGGEIDPNTLISAWQGISYGIES
AKKGYQTIMMPGQYTYFDMAQSETERGHRWAAITDTKRAYSFEPIPTDDLTPEQQKNIIGVQGALWSEYLDRPARIMEYQ
SYPRISALSEIGWSKKEDKNWEDFYGRLTHSHLQRLADMGIAFRDFPPAAIYQNGTITVTPPYEGAVVRYDAQGNEPTRQ
SALYTKPIQTKDYEHYMFRTFFNEDVASPSVKVEKLPVAVWNTSKAEVLNISENISEHVDKNGIWYLTFTPDADASANGV
VKTVSLYENDKLIQSFPEEKMLKSKPRLRFVIENYNEKNTYRLDFTVENKEAKESAAKVNFNCSPYLEPEVKVTSSMAEN
PKFPISNLEDYNVETYLRTDIACANGDWILYTFTNPVTSSKIDVLTGIPHHPRFIVNNGYVEYSYNGIDFIKGDAFDYGN
ASIYPKQPVKAVKIVITGTNNEPLMAGQDIRINP
>Mature_834_residues
MKRSVLLIAIFLSSLSTIQAQKLDIIPKPVKVEQNEGVFIIPSSVQIIVDKKAEKSAEYIKSSFSKYTGINAIVSIGNKH
KKNTIAFLVDEKMNLPNDGYKLNINKKGILVKGKSANGVLNGLQTLLQISSAKDIKKGNIPFVKIEDYPRFEWRGMMLDC
SRQFFDKQTVKNYIDWLAAHKMNVFHWHLTDDNGWRIEIKSMPDLTLKGAWRGPGEVLLPSYGSGDKRYGGFYTQEHIKE
VVAYAANRGISVMPEIEIPGHSRAVTASYPEVGCAITQELKSVQGEVKNVWCVGREENYVLLDSIIREVSGLFPFEYIHV
AGDEVNRANWENCPKCQALMVKEGFTDSFQLQNYFFRRVQKIVDKYHKKTDGWNEILKGGEIDPNTLISAWQGISYGIES
AKKGYQTIMMPGQYTYFDMAQSETERGHRWAAITDTKRAYSFEPIPTDDLTPEQQKNIIGVQGALWSEYLDRPARIMEYQ
SYPRISALSEIGWSKKEDKNWEDFYGRLTHSHLQRLADMGIAFRDFPPAAIYQNGTITVTPPYEGAVVRYDAQGNEPTRQ
SALYTKPIQTKDYEHYMFRTFFNEDVASPSVKVEKLPVAVWNTSKAEVLNISENISEHVDKNGIWYLTFTPDADASANGV
VKTVSLYENDKLIQSFPEEKMLKSKPRLRFVIENYNEKNTYRLDFTVENKEAKESAAKVNFNCSPYLEPEVKVTSSMAEN
PKFPISNLEDYNVETYLRTDIACANGDWILYTFTNPVTSSKIDVLTGIPHHPRFIVNNGYVEYSYNGIDFIKGDAFDYGN
ASIYPKQPVKAVKIVITGTNNEPLMAGQDIRINP

Specific function: Hydrolyzes rapidly p-nitrophenyl-N-acetyl-beta-D- glucosaminide (PNP-beta-GlcNAc) and 4-methylumbelliferyl-beta- GlcNAc, and slightly active on p-nitrophenyl-beta-GalNAc. Hydrolyzes aryl-N-acetyl-beta-D-glucosaminide (aryl-beta-GlcNAc), aryl-beta-GalNAc a

COG id: COG3525

COG function: function code G; N-acetyl-beta-hexosaminidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI189181666, Length=429, Percent_Identity=29.6037296037296, Blast_Score=184, Evalue=4e-46,
Organism=Homo sapiens, GI4504373, Length=433, Percent_Identity=28.4064665127021, Blast_Score=176, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI17569815, Length=438, Percent_Identity=28.0821917808219, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI281365639, Length=489, Percent_Identity=26.9938650306748, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24657474, Length=489, Percent_Identity=26.9938650306748, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24657468, Length=470, Percent_Identity=27.0212765957447, Blast_Score=136, Evalue=5e-32,
Organism=Drosophila melanogaster, GI17647501, Length=470, Percent_Identity=27.0212765957447, Blast_Score=136, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24653074, Length=477, Percent_Identity=25.1572327044025, Blast_Score=107, Evalue=4e-23,
Organism=Drosophila melanogaster, GI45551090, Length=477, Percent_Identity=25.1572327044025, Blast_Score=107, Evalue=5e-23,
Organism=Drosophila melanogaster, GI17933586, Length=416, Percent_Identity=24.7596153846154, Blast_Score=90, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR001540
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 94775; Mature: 94775

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRSVLLIAIFLSSLSTIQAQKLDIIPKPVKVEQNEGVFIIPSSVQIIVDKKAEKSAEYI
CCCCCEEHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEECCCEEEEEECCHHHHHHHH
KSSFSKYTGINAIVSIGNKHKKNTIAFLVDEKMNLPNDGYKLNINKKGILVKGKSANGVL
HHHHHHHCCCHHEEECCCCCCCCEEEEEEECCCCCCCCCEEEEECCCEEEEECCCCCHHH
NGLQTLLQISSAKDIKKGNIPFVKIEDYPRFEWRGMMLDCSRQFFDKQTVKNYIDWLAAH
HHHHHHHHHHCCCCCCCCCCCEEEECCCCCCEEECEEEHHHHHHHHHHHHHHHHHHHHHC
KMNVFHWHLTDDNGWRIEIKSMPDLTLKGAWRGPGEVLLPSYGSGDKRYGGFYTQEHIKE
CCEEEEEEEECCCCCEEEEECCCCEEEECCCCCCCCEEECCCCCCCCCCCCCCCHHHHHH
VVAYAANRGISVMPEIEIPGHSRAVTASYPEVGCAITQELKSVQGEVKNVWCVGREENYV
HHHHHHCCCCEEEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCEE
LLDSIIREVSGLFPFEYIHVAGDEVNRANWENCPKCQALMVKEGFTDSFQLQNYFFRRVQ
HHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHEEEEECCCCCHHHHHHHHHHHHH
KIVDKYHKKTDGWNEILKGGEIDPNTLISAWQGISYGIESAKKGYQTIMMPGQYTYFDMA
HHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHCCHHHHHHHHCCCCEEEEECCCEEEEECH
QSETERGHRWAAITDTKRAYSFEPIPTDDLTPEQQKNIIGVQGALWSEYLDRPARIMEYQ
HHHHHCCCEEEEEECCCCCEECCCCCCCCCCCHHHCCEEEECCHHHHHHHCCCHHHHHHC
SYPRISALSEIGWSKKEDKNWEDFYGRLTHSHLQRLADMGIAFRDFPPAAIYQNGTITVT
CCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCHHEEECCEEEEC
PPYEGAVVRYDAQGNEPTRQSALYTKPIQTKDYEHYMFRTFFNEDVASPSVKVEKLPVAV
CCCCCEEEEEECCCCCCCHHCCEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEE
WNTSKAEVLNISENISEHVDKNGIWYLTFTPDADASANGVVKTVSLYENDKLIQSFPEEK
ECCCCCEEEECHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEEEECCCHHHHHCCHHH
MLKSKPRLRFVIENYNEKNTYRLDFTVENKEAKESAAKVNFNCSPYLEPEVKVTSSMAEN
HHHCCCCEEEEEECCCCCCEEEEEEEECCCHHHHHHHEEECCCCCCCCCCCEEHHHHHCC
PKFPISNLEDYNVETYLRTDIACANGDWILYTFTNPVTSSKIDVLTGIPHHPRFIVNNGY
CCCCCCCCCCCCCEEEEEEEEEEECCCEEEEEECCCCCCCCEEEEECCCCCCEEEEECCE
VEYSYNGIDFIKGDAFDYGNASIYPKQPVKAVKIVITGTNNEPLMAGQDIRINP
EEEEECCEEEEECCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEECCCCCEECC
>Mature Secondary Structure
MKRSVLLIAIFLSSLSTIQAQKLDIIPKPVKVEQNEGVFIIPSSVQIIVDKKAEKSAEYI
CCCCCEEHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEECCCEEEEEECCHHHHHHHH
KSSFSKYTGINAIVSIGNKHKKNTIAFLVDEKMNLPNDGYKLNINKKGILVKGKSANGVL
HHHHHHHCCCHHEEECCCCCCCCEEEEEEECCCCCCCCCEEEEECCCEEEEECCCCCHHH
NGLQTLLQISSAKDIKKGNIPFVKIEDYPRFEWRGMMLDCSRQFFDKQTVKNYIDWLAAH
HHHHHHHHHHCCCCCCCCCCCEEEECCCCCCEEECEEEHHHHHHHHHHHHHHHHHHHHHC
KMNVFHWHLTDDNGWRIEIKSMPDLTLKGAWRGPGEVLLPSYGSGDKRYGGFYTQEHIKE
CCEEEEEEEECCCCCEEEEECCCCEEEECCCCCCCCEEECCCCCCCCCCCCCCCHHHHHH
VVAYAANRGISVMPEIEIPGHSRAVTASYPEVGCAITQELKSVQGEVKNVWCVGREENYV
HHHHHHCCCCEEEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCEE
LLDSIIREVSGLFPFEYIHVAGDEVNRANWENCPKCQALMVKEGFTDSFQLQNYFFRRVQ
HHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHEEEEECCCCCHHHHHHHHHHHHH
KIVDKYHKKTDGWNEILKGGEIDPNTLISAWQGISYGIESAKKGYQTIMMPGQYTYFDMA
HHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHCCHHHHHHHHCCCCEEEEECCCEEEEECH
QSETERGHRWAAITDTKRAYSFEPIPTDDLTPEQQKNIIGVQGALWSEYLDRPARIMEYQ
HHHHHCCCEEEEEECCCCCEECCCCCCCCCCCHHHCCEEEECCHHHHHHHCCCHHHHHHC
SYPRISALSEIGWSKKEDKNWEDFYGRLTHSHLQRLADMGIAFRDFPPAAIYQNGTITVT
CCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCHHEEECCEEEEC
PPYEGAVVRYDAQGNEPTRQSALYTKPIQTKDYEHYMFRTFFNEDVASPSVKVEKLPVAV
CCCCCEEEEEECCCCCCCHHCCEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEE
WNTSKAEVLNISENISEHVDKNGIWYLTFTPDADASANGVVKTVSLYENDKLIQSFPEEK
ECCCCCEEEECHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEEEECCCHHHHHCCHHH
MLKSKPRLRFVIENYNEKNTYRLDFTVENKEAKESAAKVNFNCSPYLEPEVKVTSSMAEN
HHHCCCCEEEEEECCCCCCEEEEEEEECCCHHHHHHHEEECCCCCCCCCCCEEHHHHHCC
PKFPISNLEDYNVETYLRTDIACANGDWILYTFTNPVTSSKIDVLTGIPHHPRFIVNNGY
CCCCCCCCCCCCCEEEEEEEEEEECCCEEEEEECCCCCCCCEEEEECCCCCCEEEEECCE
VEYSYNGIDFIKGDAFDYGNASIYPKQPVKAVKIVITGTNNEPLMAGQDIRINP
EEEEECCEEEEECCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEECCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969205 [H]