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The map label for this gene is yqjI [H]

Identifier: 146302526

GI number: 146302526

Start: 5799423

End: 5800832

Strand: Direct

Name: yqjI [H]

Synonym: Fjoh_4799

Alternate gene names: 146302526

Gene position: 5799423-5800832 (Clockwise)

Preceding gene: 146302525

Following gene: 146302527

Centisome position: 95.12

GC content: 38.44

Gene sequence:

>1410_bases
ATGAGCAAATTTGATTTTGGAATTGTAGGACTCGGTGTAATGGGCCGTAACTTACTTTTAAATATCGCCAGCCATAACTT
TGCGGCTGCAGGTTTAGACTTAGATACCGAAAAAGTCAACTCTCTTCAACAAGAAGCTGACGCCGCCCACACAATTGAAG
CGACAACAGATGTAAAACATTTCGTAGAGCTTATTCAACAACCTAGAGCGATTATGCTTTTAGTTCCTGCCGGAAAACCG
GTCGACAGCGCTATAGCCAGCTTATTACCACATTTAGATAAAGGTGACATCATAATCGATGGCGGAAACACTTATTTTAC
AGATACTGACAGACGATTTATAGAATTATCTGAAAAAGGTATTCATTTCTTCGGAATGGGAATTTCAGGCGGTGAAAAAG
GTGCAAGATTCGGTCCTGCTATGATGCCGGGCGGTGATCAAAAAGCATACGAAAGACTTCGTCCTATTTTTGAGGCTATT
GCTGCAAAAGTAGACGGCGAACCTTGTGTAGAATATTTAGGAAACGGTTCTGCAGGAAACTATGTAAAAATGGTTCATAA
CGGAATCGAATACGGAATTATGCAGTTAATTTCTGAGATTTATGACCTTATGAAAAGAGGTTATAACTTAGACGATGAAA
CGATTCAAAAAACTTTTGAAGAATGGAATCAAACTGATGATCTAAGATCGTATCTTATTGAAATTACTGGAAAAATTTTA
AAACAAAAAGACGAAGACGGAAGCCTTCTTATCAATAAAATTTCAGATTGGGCAAAATCTAAAGGAACAGGAAAATGGAC
TTCACAAAATGCAATGGATTTGCAGGTTCCGGTTCCAACTATCGACGCCGCTGTTATAATGCGCGATATGTCTAAAACAA
AACCTGAAAGAATTGAAGCTGCAAAAAACTTAGTTTGGAATACTCCTGAAAGTAATGTAAATACCAGCGAAGCAATTGCT
GCTTTAAAATCGGCGTTATACCTTTCTATTGTTGTAACGTATGCTCAGGGATTAGCTCAGCTTCATACTGCTTCTAAAGA
ATACAATTACGGATTAAATCTGGAAACTGTTGCCAAAATCTGGCGCGGAGGCTGTATTATTCGTGCAACTATTCTGGAAG
ATTTCAGAAAAGCGTATGTCGCAAAATCTGATTTACCAAACTTACTTTTAGATTCTGGAATAGCTTCAAAATTAACCGAA
AACCAAGCAGGAATGAGAGCTGTAATTCAGTTTGCCGTTCAAAAAGGATTACCTGCGGCTGGTTTGATGAATTCGTTAGC
TTATTTTGACTCTTATAGATCTGCTAATCTGCCTACAAATTTAATTCAGGCACAGCGCGATTTCTTTGGGGCTCATACTT
ACGAACGCATCGACAAAGAAGGTGTTTTCCACACACAATGGGCTGAATAA

Upstream 100 bases:

>100_bases
CTTGTTTTTCTGCAAAGAACTGATTGAAAAAGTATTACTGATTTTTTTCTTACTTTTTTCCAGAAAAACATTCTTTAATA
ATTTTAGTTAATTGAAAACT

Downstream 100 bases:

>100_bases
GCAACTTAAAAAAAAGCAACACAACTACACACAATGACTAAAAATAAACTTAAAAATCCAACAATCATTGTTATTTTTGG
AGGAACCGGAGACTTAGCAA

Product: 6-phosphogluconate dehydrogenase, decarboxylating

Products: NA

Alternate protein names: GNTZII [H]

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MSKFDFGIVGLGVMGRNLLLNIASHNFAAAGLDLDTEKVNSLQQEADAAHTIEATTDVKHFVELIQQPRAIMLLVPAGKP
VDSAIASLLPHLDKGDIIIDGGNTYFTDTDRRFIELSEKGIHFFGMGISGGEKGARFGPAMMPGGDQKAYERLRPIFEAI
AAKVDGEPCVEYLGNGSAGNYVKMVHNGIEYGIMQLISEIYDLMKRGYNLDDETIQKTFEEWNQTDDLRSYLIEITGKIL
KQKDEDGSLLINKISDWAKSKGTGKWTSQNAMDLQVPVPTIDAAVIMRDMSKTKPERIEAAKNLVWNTPESNVNTSEAIA
ALKSALYLSIVVTYAQGLAQLHTASKEYNYGLNLETVAKIWRGGCIIRATILEDFRKAYVAKSDLPNLLLDSGIASKLTE
NQAGMRAVIQFAVQKGLPAAGLMNSLAYFDSYRSANLPTNLIQAQRDFFGAHTYERIDKEGVFHTQWAE

Sequences:

>Translated_469_residues
MSKFDFGIVGLGVMGRNLLLNIASHNFAAAGLDLDTEKVNSLQQEADAAHTIEATTDVKHFVELIQQPRAIMLLVPAGKP
VDSAIASLLPHLDKGDIIIDGGNTYFTDTDRRFIELSEKGIHFFGMGISGGEKGARFGPAMMPGGDQKAYERLRPIFEAI
AAKVDGEPCVEYLGNGSAGNYVKMVHNGIEYGIMQLISEIYDLMKRGYNLDDETIQKTFEEWNQTDDLRSYLIEITGKIL
KQKDEDGSLLINKISDWAKSKGTGKWTSQNAMDLQVPVPTIDAAVIMRDMSKTKPERIEAAKNLVWNTPESNVNTSEAIA
ALKSALYLSIVVTYAQGLAQLHTASKEYNYGLNLETVAKIWRGGCIIRATILEDFRKAYVAKSDLPNLLLDSGIASKLTE
NQAGMRAVIQFAVQKGLPAAGLMNSLAYFDSYRSANLPTNLIQAQRDFFGAHTYERIDKEGVFHTQWAE
>Mature_468_residues
SKFDFGIVGLGVMGRNLLLNIASHNFAAAGLDLDTEKVNSLQQEADAAHTIEATTDVKHFVELIQQPRAIMLLVPAGKPV
DSAIASLLPHLDKGDIIIDGGNTYFTDTDRRFIELSEKGIHFFGMGISGGEKGARFGPAMMPGGDQKAYERLRPIFEAIA
AKVDGEPCVEYLGNGSAGNYVKMVHNGIEYGIMQLISEIYDLMKRGYNLDDETIQKTFEEWNQTDDLRSYLIEITGKILK
QKDEDGSLLINKISDWAKSKGTGKWTSQNAMDLQVPVPTIDAAVIMRDMSKTKPERIEAAKNLVWNTPESNVNTSEAIAA
LKSALYLSIVVTYAQGLAQLHTASKEYNYGLNLETVAKIWRGGCIIRATILEDFRKAYVAKSDLPNLLLDSGIASKLTEN
QAGMRAVIQFAVQKGLPAAGLMNSLAYFDSYRSANLPTNLIQAQRDFFGAHTYERIDKEGVFHTQWAE

Specific function: Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH [H]

COG id: COG0362

COG function: function code G; 6-phosphogluconate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 6-phosphogluconate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI40068518, Length=473, Percent_Identity=45.2431289640592, Blast_Score=387, Evalue=1e-107,
Organism=Escherichia coli, GI1788341, Length=468, Percent_Identity=51.2820512820513, Blast_Score=465, Evalue=1e-132,
Organism=Caenorhabditis elegans, GI17542558, Length=472, Percent_Identity=44.9152542372881, Blast_Score=423, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6321695, Length=453, Percent_Identity=48.7858719646799, Blast_Score=437, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6321977, Length=453, Percent_Identity=47.4613686534216, Blast_Score=407, Evalue=1e-114,
Organism=Drosophila melanogaster, GI24639279, Length=466, Percent_Identity=45.0643776824034, Blast_Score=376, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR006114
- InterPro:   IPR006113
- InterPro:   IPR006115
- InterPro:   IPR006184
- InterPro:   IPR013328
- InterPro:   IPR012284
- InterPro:   IPR016040
- InterPro:   IPR006183 [H]

Pfam domain/function: PF00393 6PGD; PF03446 NAD_binding_2 [H]

EC number: =1.1.1.44 [H]

Molecular weight: Translated: 51699; Mature: 51567

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKFDFGIVGLGVMGRNLLLNIASHNFAAAGLDLDTEKVNSLQQEADAAHTIEATTDVKH
CCCCCCCCEEHHHHCHHHHEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FVELIQQPRAIMLLVPAGKPVDSAIASLLPHLDKGDIIIDGGNTYFTDTDRRFIELSEKG
HHHHHHCCCEEEEEECCCCCHHHHHHHHCCCCCCCCEEEECCCEEECCCCCHHHHHHCCC
IHFFGMGISGGEKGARFGPAMMPGGDQKAYERLRPIFEAIAAKVDGEPCVEYLGNGSAGN
EEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCC
YVKMVHNGIEYGIMQLISEIYDLMKRGYNLDDETIQKTFEEWNQTDDLRSYLIEITGKIL
HHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
KQKDEDGSLLINKISDWAKSKGTGKWTSQNAMDLQVPVPTIDAAVIMRDMSKTKPERIEA
HCCCCCCCEEHHHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCHHHHHH
AKNLVWNTPESNVNTSEAIAALKSALYLSIVVTYAQGLAQLHTASKEYNYGLNLETVAKI
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
WRGGCIIRATILEDFRKAYVAKSDLPNLLLDSGIASKLTENQAGMRAVIQFAVQKGLPAA
HCCCCEEEHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHH
GLMNSLAYFDSYRSANLPTNLIQAQRDFFGAHTYERIDKEGVFHTQWAE
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SKFDFGIVGLGVMGRNLLLNIASHNFAAAGLDLDTEKVNSLQQEADAAHTIEATTDVKH
CCCCCCCEEHHHHCHHHHEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FVELIQQPRAIMLLVPAGKPVDSAIASLLPHLDKGDIIIDGGNTYFTDTDRRFIELSEKG
HHHHHHCCCEEEEEECCCCCHHHHHHHHCCCCCCCCEEEECCCEEECCCCCHHHHHHCCC
IHFFGMGISGGEKGARFGPAMMPGGDQKAYERLRPIFEAIAAKVDGEPCVEYLGNGSAGN
EEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCC
YVKMVHNGIEYGIMQLISEIYDLMKRGYNLDDETIQKTFEEWNQTDDLRSYLIEITGKIL
HHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
KQKDEDGSLLINKISDWAKSKGTGKWTSQNAMDLQVPVPTIDAAVIMRDMSKTKPERIEA
HCCCCCCCEEHHHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCHHHHHH
AKNLVWNTPESNVNTSEAIAALKSALYLSIVVTYAQGLAQLHTASKEYNYGLNLETVAKI
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
WRGGCIIRATILEDFRKAYVAKSDLPNLLLDSGIASKLTENQAGMRAVIQFAVQKGLPAA
HCCCCEEEHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHH
GLMNSLAYFDSYRSANLPTNLIQAQRDFFGAHTYERIDKEGVFHTQWAE
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10568751; 9298659 [H]