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The map label for this gene is pbpE [H]

Identifier: 146302515

GI number: 146302515

Start: 5786036

End: 5787238

Strand: Direct

Name: pbpE [H]

Synonym: Fjoh_4788

Alternate gene names: 146302515

Gene position: 5786036-5787238 (Clockwise)

Preceding gene: 146302513

Following gene: 146302525

Centisome position: 94.9

GC content: 33.25

Gene sequence:

>1203_bases
ATGCAAATGATTTTCCTTAAAAAAACAAAGATACCACAAATACTTTTTACAGTATTAGTTTTAAGTTCATGTGGTAATGA
CAAAAAAACACAAACAGCTGCTGCCCAAACAGTCGAAGATACTTTACCTAAAATGAAGCCGTTAGGTCCTGAACCTAAAG
TTTCACAAGCTTATAAAAACTCCGTTGTTGGAAGAATAAACCACTTTTACAACAAAAACTGGCCTAATAATAACATGAAC
GGAAGCTTTTTAGTTGCCCGAAATGGTCAGATTATCTTCGAAAGATATAATGGTTTTGCTAATAAAAACGAAGGGACAAA
AATAACGCCCGAAACCCCGGTGCAAATTGCCTCTGTTAGTAAAGTTCTAACAGCTACAGCAGTTTTAAAACTGGTTAATG
CCGGAAAAATAGAATTAGATCAAAAAGTAAATACGATTTTAAAAACGTTTCCTTACGAAGACTGCACGATTAGAATGCTT
TTAGATCACCGTACCGGAATGCGTAATTATGCTTATTTTACAGATAGAGATAAATCTATTTGGGACAGACATAACCAGCT
TACTAACAAAGATATTTTAGATATTCTTGCCACGAAAGATATTGGTTTAGAATCTAAAACAGGAACACGTTTCAGCTATT
GCAATACTAATTATGCAATGCTGGCACTTATTATTGAGAAAATTACAGGTTTAAGTTATAAGGAAGCAATGTCTGAAATG
ATTTTTAAACCTTTAGGAATGACTCATACCTATGTTTTTGATGATGATAAAGACAGAAAAAAAATTGTTCCTTCTTACAA
AGGAAATGGTGTAGAAATAGGTTTTGATTATTTAGATAATGTTTACGGAGATAAAAACATTTTCTCGACTGCACGAGATT
TGTTAAAATTTGACCGCGCCAGACAATCACCTGACTTTTTAAAACCTGAATTACTGAAACAGGTATATACCGGCTACAGT
AACGAACGCAAAGGAACAAAAAATTACGGTTTAGGAATTAGAATGATTAATTGGGAAACCGGTCAGAATTTTTATTTCCA
TAATGGCTGGTGGCACGGAAATACCTCATCTTATATTACTTTGATGAAAGAACATGTTACGATAATTGCATTGTCTAATA
AGATGACAAGAAACACTTATGCAGTACGTAAACTGGCTCCTATTTTTGGCGATTATCCTTTTAATTTTAAAGACGAAGAG
TAA

Upstream 100 bases:

>100_bases
AAAAAACAACATGTTAAAACTATGTTAAAAAATACGTTTTTAAGCCTCAAAATTGAGAAAACAACAAAATTGAATTCGAT
ATATTTGTTTTTAAAGAACG

Downstream 100 bases:

>100_bases
AATTATAGTCGTAAAGACGAAAGTCAAAAGTCGTAAAGTCTTAAAAACATTGCCAATGCTGACTTTGGACTTTCGAGTTT
GGACTTTATGACTTTTTTTT

Product: beta-lactamase

Products: NA

Alternate protein names: PBP 4*; PBP 4A; Penicillin-binding protein E [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MQMIFLKKTKIPQILFTVLVLSSCGNDKKTQTAAAQTVEDTLPKMKPLGPEPKVSQAYKNSVVGRINHFYNKNWPNNNMN
GSFLVARNGQIIFERYNGFANKNEGTKITPETPVQIASVSKVLTATAVLKLVNAGKIELDQKVNTILKTFPYEDCTIRML
LDHRTGMRNYAYFTDRDKSIWDRHNQLTNKDILDILATKDIGLESKTGTRFSYCNTNYAMLALIIEKITGLSYKEAMSEM
IFKPLGMTHTYVFDDDKDRKKIVPSYKGNGVEIGFDYLDNVYGDKNIFSTARDLLKFDRARQSPDFLKPELLKQVYTGYS
NERKGTKNYGLGIRMINWETGQNFYFHNGWWHGNTSSYITLMKEHVTIIALSNKMTRNTYAVRKLAPIFGDYPFNFKDEE

Sequences:

>Translated_400_residues
MQMIFLKKTKIPQILFTVLVLSSCGNDKKTQTAAAQTVEDTLPKMKPLGPEPKVSQAYKNSVVGRINHFYNKNWPNNNMN
GSFLVARNGQIIFERYNGFANKNEGTKITPETPVQIASVSKVLTATAVLKLVNAGKIELDQKVNTILKTFPYEDCTIRML
LDHRTGMRNYAYFTDRDKSIWDRHNQLTNKDILDILATKDIGLESKTGTRFSYCNTNYAMLALIIEKITGLSYKEAMSEM
IFKPLGMTHTYVFDDDKDRKKIVPSYKGNGVEIGFDYLDNVYGDKNIFSTARDLLKFDRARQSPDFLKPELLKQVYTGYS
NERKGTKNYGLGIRMINWETGQNFYFHNGWWHGNTSSYITLMKEHVTIIALSNKMTRNTYAVRKLAPIFGDYPFNFKDEE
>Mature_400_residues
MQMIFLKKTKIPQILFTVLVLSSCGNDKKTQTAAAQTVEDTLPKMKPLGPEPKVSQAYKNSVVGRINHFYNKNWPNNNMN
GSFLVARNGQIIFERYNGFANKNEGTKITPETPVQIASVSKVLTATAVLKLVNAGKIELDQKVNTILKTFPYEDCTIRML
LDHRTGMRNYAYFTDRDKSIWDRHNQLTNKDILDILATKDIGLESKTGTRFSYCNTNYAMLALIIEKITGLSYKEAMSEM
IFKPLGMTHTYVFDDDKDRKKIVPSYKGNGVEIGFDYLDNVYGDKNIFSTARDLLKFDRARQSPDFLKPELLKQVYTGYS
NERKGTKNYGLGIRMINWETGQNFYFHNGWWHGNTSSYITLMKEHVTIIALSNKMTRNTYAVRKLAPIFGDYPFNFKDEE

Specific function: Probably involved in peptidoglycan modification during cortex synthesis [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-lactamase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI115533026, Length=201, Percent_Identity=31.3432835820896, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17550934, Length=231, Percent_Identity=26.4069264069264, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466
- InterPro:   IPR021860 [H]

Pfam domain/function: PF00144 Beta-lactamase; PF11954 DUF3471 [H]

EC number: NA

Molecular weight: Translated: 45885; Mature: 45885

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMIFLKKTKIPQILFTVLVLSSCGNDKKTQTAAAQTVEDTLPKMKPLGPEPKVSQAYKN
CCEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
SVVGRINHFYNKNWPNNNMNGSFLVARNGQIIFERYNGFANKNEGTKITPETPVQIASVS
HHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEEECCCCCCCCCCCEECCCCCHHHHHHH
KVLTATAVLKLVNAGKIELDQKVNTILKTFPYEDCTIRMLLDHRTGMRNYAYFTDRDKSI
HHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCHHH
WDRHNQLTNKDILDILATKDIGLESKTGTRFSYCNTNYAMLALIIEKITGLSYKEAMSEM
HHHHHHCCCHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCHHHHHHHH
IFKPLGMTHTYVFDDDKDRKKIVPSYKGNGVEIGFDYLDNVYGDKNIFSTARDLLKFDRA
HHHCCCCEEEEEECCCCCHHHCCCCCCCCCEEEEHHHHHHHCCCHHHHHHHHHHHHHHHH
RQSPDFLKPELLKQVYTGYSNERKGTKNYGLGIRMINWETGQNFYFHNGWWHGNTSSYIT
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCEEEECCEECCCCCHHHE
LMKEHVTIIALSNKMTRNTYAVRKLAPIFGDYPFNFKDEE
EEECCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MQMIFLKKTKIPQILFTVLVLSSCGNDKKTQTAAAQTVEDTLPKMKPLGPEPKVSQAYKN
CCEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
SVVGRINHFYNKNWPNNNMNGSFLVARNGQIIFERYNGFANKNEGTKITPETPVQIASVS
HHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEEECCCCCCCCCCCEECCCCCHHHHHHH
KVLTATAVLKLVNAGKIELDQKVNTILKTFPYEDCTIRMLLDHRTGMRNYAYFTDRDKSI
HHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCHHH
WDRHNQLTNKDILDILATKDIGLESKTGTRFSYCNTNYAMLALIIEKITGLSYKEAMSEM
HHHHHHCCCHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCHHHHHHHH
IFKPLGMTHTYVFDDDKDRKKIVPSYKGNGVEIGFDYLDNVYGDKNIFSTARDLLKFDRA
HHHCCCCEEEEEECCCCCHHHCCCCCCCCCEEEEHHHHHHHCCCHHHHHHHHHHHHHHHH
RQSPDFLKPELLKQVYTGYSNERKGTKNYGLGIRMINWETGQNFYFHNGWWHGNTSSYIT
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCEEEECCEECCCCCHHHE
LMKEHVTIIALSNKMTRNTYAVRKLAPIFGDYPFNFKDEE
EEECCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8491712; 9384377 [H]