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The map label for this gene is 146302426

Identifier: 146302426

GI number: 146302426

Start: 5675485

End: 5676588

Strand: Direct

Name: 146302426

Synonym: Fjoh_4699

Alternate gene names: NA

Gene position: 5675485-5676588 (Clockwise)

Preceding gene: 146302425

Following gene: 146302427

Centisome position: 93.09

GC content: 33.88

Gene sequence:

>1104_bases
ATGATTACATTTCTAATTCTTATAATCCTAATAGGTTTTATTGTTTACAATTTCTTGCAGCATCCAAAATTTGGAAAAGC
ACCTTCCGGCGAAAGATTCACTTTAATTCAGAACTCGCCTCAATATAAAAACGGGAAATTCGAGAATCAGAGCTTTACGC
CAGATTTGGCTGAAGGTGCAAGCATGGCTGGAGTTTTACTTGAATTTTTCTTCAAAAAAGTAGAACGAAAAATCCCAACC
GATTTAATTCCGTCTGTAAAAACCAATCTGCATGAACTATCTATAGAAGAGGATGTTTTGGTTTGGTTTGGACATTCTTC
TTATTTTATTCAGCTTGAAGGAAAACGTTTTTTAATCGATCCTGTTTTTAGCGGCAATGCCTCTCCTATTTCGGGAACGA
CAAAGTCATTTAAAGGTTCAGATATCTATACTGTTGATGATCTTCCGGAAATTGATTATTTATTGATTACACACGATCAT
TATGATCATTTAGATTATGAAACCATTCTTAAATTAAAACCCAAAACAAAAAAAGTAATTACGGCTCTTGGTGTAGGTTC
GCATTTTGAATTTTGGGGATTTCCAACAGAAAATGTAATTGAAAAAGACTGGTTTGAAAAAATTGAATTAGATGAAAATC
TAACATTACATACAACTCCTTCAAGACATTTTTCCGGCAGAAGTTTTAAACGCTGCAACACACTTTGGACTTCTTTTGTT
TTAGAAACTAAAGACTTTAAAATGTATTTGGGCGGAGACAGCGGTTATGACAAGCATTTTGCTGAAATTGGAGAAAAATA
CGGCCCGTTTGATATTGCTTTGATCGACAACGGCCAATACAACGAAAAATGGAAATACATTCATAACATGCCCGAAGATG
TTATAAAAGCGATGAAAGACTTACATGCAAAAAGAGTTTTTCCGGTTCATTCTTCAAAATTTGCTTTATCGCTTCATTCC
TGGGACGAACCTTTGATAAGAGTAACAGAATTAAATAGTTTGAGCGAAAAACCAATTCCGTTAATTACACCAATGATTGG
CGAATTAGTCGAATTAAAAAACGAAAATCAACAATTTAAACAATGGTGGAAAGGGGTTAATTAA

Upstream 100 bases:

>100_bases
TTTACATTAAAAAATTAGCTGATATCGATATTGACATCTTAAAAAAGGTAATTTTACTTTCGATTGATTACACTCAAAAA
CTATATCCCCAAAAATAAAA

Downstream 100 bases:

>100_bases
TTGTGAATTATGAATGGTTAATTATGAATTATAATTGGAACCTGAAAACCTGAAACTTGAAACCTGAAAACCAAAAATGA
AAACCAAAATAAACTTCTTA

Product: Zn-dependent hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MITFLILIILIGFIVYNFLQHPKFGKAPSGERFTLIQNSPQYKNGKFENQSFTPDLAEGASMAGVLLEFFFKKVERKIPT
DLIPSVKTNLHELSIEEDVLVWFGHSSYFIQLEGKRFLIDPVFSGNASPISGTTKSFKGSDIYTVDDLPEIDYLLITHDH
YDHLDYETILKLKPKTKKVITALGVGSHFEFWGFPTENVIEKDWFEKIELDENLTLHTTPSRHFSGRSFKRCNTLWTSFV
LETKDFKMYLGGDSGYDKHFAEIGEKYGPFDIALIDNGQYNEKWKYIHNMPEDVIKAMKDLHAKRVFPVHSSKFALSLHS
WDEPLIRVTELNSLSEKPIPLITPMIGELVELKNENQQFKQWWKGVN

Sequences:

>Translated_367_residues
MITFLILIILIGFIVYNFLQHPKFGKAPSGERFTLIQNSPQYKNGKFENQSFTPDLAEGASMAGVLLEFFFKKVERKIPT
DLIPSVKTNLHELSIEEDVLVWFGHSSYFIQLEGKRFLIDPVFSGNASPISGTTKSFKGSDIYTVDDLPEIDYLLITHDH
YDHLDYETILKLKPKTKKVITALGVGSHFEFWGFPTENVIEKDWFEKIELDENLTLHTTPSRHFSGRSFKRCNTLWTSFV
LETKDFKMYLGGDSGYDKHFAEIGEKYGPFDIALIDNGQYNEKWKYIHNMPEDVIKAMKDLHAKRVFPVHSSKFALSLHS
WDEPLIRVTELNSLSEKPIPLITPMIGELVELKNENQQFKQWWKGVN
>Mature_367_residues
MITFLILIILIGFIVYNFLQHPKFGKAPSGERFTLIQNSPQYKNGKFENQSFTPDLAEGASMAGVLLEFFFKKVERKIPT
DLIPSVKTNLHELSIEEDVLVWFGHSSYFIQLEGKRFLIDPVFSGNASPISGTTKSFKGSDIYTVDDLPEIDYLLITHDH
YDHLDYETILKLKPKTKKVITALGVGSHFEFWGFPTENVIEKDWFEKIELDENLTLHTTPSRHFSGRSFKRCNTLWTSFV
LETKDFKMYLGGDSGYDKHFAEIGEKYGPFDIALIDNGQYNEKWKYIHNMPEDVIKAMKDLHAKRVFPVHSSKFALSLHS
WDEPLIRVTELNSLSEKPIPLITPMIGELVELKNENQQFKQWWKGVN

Specific function: Unknown

COG id: COG2220

COG function: function code R; Predicted Zn-dependent hydrolases of the beta-lactamase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To K.pneumoniae romA [H]

Homologues:

Organism=Homo sapiens, GI170932483, Length=316, Percent_Identity=31.9620253164557, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI170932481, Length=316, Percent_Identity=31.9620253164557, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17543102, Length=343, Percent_Identity=28.5714285714286, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI25148824, Length=343, Percent_Identity=28.5714285714286, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17543100, Length=343, Percent_Identity=28.5714285714286, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17543104, Length=276, Percent_Identity=30.0724637681159, Blast_Score=116, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6325154, Length=235, Percent_Identity=33.6170212765957, Blast_Score=106, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 42380; Mature: 42380

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITFLILIILIGFIVYNFLQHPKFGKAPSGERFTLIQNSPQYKNGKFENQSFTPDLAEGA
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHH
SMAGVLLEFFFKKVERKIPTDLIPSVKTNLHELSIEEDVLVWFGHSSYFIQLEGKRFLID
HHHHHHHHHHHHHHHHHCCHHHCCHHHCCHHHCCCCCCEEEEEECCEEEEEECCCEEEEE
PVFSGNASPISGTTKSFKGSDIYTVDDLPEIDYLLITHDHYDHLDYETILKLKPKTKKVI
EEECCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEECCCCCCCCHHHHEEECCCHHHHH
TALGVGSHFEFWGFPTENVIEKDWFEKIELDENLTLHTTPSRHFSGRSFKRCNTLWTSFV
HHHCCCCCCEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHE
LETKDFKMYLGGDSGYDKHFAEIGEKYGPFDIALIDNGQYNEKWKYIHNMPEDVIKAMKD
EECCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHCCCHHHHHHHHH
LHAKRVFPVHSSKFALSLHSWDEPLIRVTELNSLSEKPIPLITPMIGELVELKNENQQFK
HHHHEECEECCCCEEEEECCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCHHHH
QWWKGVN
HHHCCCC
>Mature Secondary Structure
MITFLILIILIGFIVYNFLQHPKFGKAPSGERFTLIQNSPQYKNGKFENQSFTPDLAEGA
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHH
SMAGVLLEFFFKKVERKIPTDLIPSVKTNLHELSIEEDVLVWFGHSSYFIQLEGKRFLID
HHHHHHHHHHHHHHHHHCCHHHCCHHHCCHHHCCCCCCEEEEEECCEEEEEECCCEEEEE
PVFSGNASPISGTTKSFKGSDIYTVDDLPEIDYLLITHDHYDHLDYETILKLKPKTKKVI
EEECCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEECCCCCCCCHHHHEEECCCHHHHH
TALGVGSHFEFWGFPTENVIEKDWFEKIELDENLTLHTTPSRHFSGRSFKRCNTLWTSFV
HHHCCCCCCEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHE
LETKDFKMYLGGDSGYDKHFAEIGEKYGPFDIALIDNGQYNEKWKYIHNMPEDVIKAMKD
EECCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHCCCHHHHHHHHH
LHAKRVFPVHSSKFALSLHSWDEPLIRVTELNSLSEKPIPLITPMIGELVELKNENQQFK
HHHHEECEECCCCEEEEECCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCHHHH
QWWKGVN
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]