Click here to switch to the map view.

The map label for this gene is flp [H]

Identifier: 146302424

GI number: 146302424

Start: 5674017

End: 5675054

Strand: Direct

Name: flp [H]

Synonym: Fjoh_4697

Alternate gene names: 146302424

Gene position: 5674017-5675054 (Clockwise)

Preceding gene: 146302423

Following gene: 146302425

Centisome position: 93.06

GC content: 32.66

Gene sequence:

>1038_bases
ATGAAATTTTTTTCTTTTACATTTCTATTGTTTATCCTATGCAGCTGTCATTCATCGGCACAAAAAAAAGACAATTACGC
TTCAAAAATTGACAGCATTATTCAAAACAGCACTTCTTCAGATTTTAATGGTGTGGTTTTAATTTCAAAAAACGGAAAAA
CATTATATTCAAAAGTAAAAGGATCTGCCAATTTTGAAACCCAAAAACCTTTAACAATTGATACTCAATTTGAGATCATG
TCAAACAGCAAACAGATTGCTGCTGTTTTGGTTTTACTAGAAGCCGAAAAAGGCAGAGTCGATTTAAATTCACCCATAAA
AAAATACCTTCCTGAATTAACCCAAACCTGGGCTGACACGGTTACGGTACACCAGCTTTTAAATCATTCGCACGGAATTG
TCGATTTGCAGAAACCTTTGGCATTTAAACCCGGAACTCAATTTAAATACGGAAATTTAAGTTTTAATTTAATTGGTAAA
ATTGTTGAATTCAGTACAAAGAAAAGTTACAACGAAACTGCCGGCGCACTTTTTAAGAAATTAAAAATGAACCAGACTTT
TTGTTATTCTAAAGACAAAGCACAGAATCTGGCAACAGGATATTTCTCCTCAAAAAATAAAATGGAACCTGTAACTGGTT
CACAAATTACACCTGAAAGTTTTGGCGCCGATGGCATAATTTCAACTGTTTCAGATTTGGCGATCTGGAATAACAACCTT
CATAAAGGAAAAATACTAAAACCAGAATCGTATAAACTGCTGACAAAAAATACGATTTTATCACAGCATAATTTCTTTGG
AAAAGAAAAAGAGCCTTACGGATACGGAATACGAATTATTGAAAAAGAAACCGTAAAATATTTAGGCCATACCGGGTTAG
GCGACGGGTTTTCTTCTGTAAATTTGTATTTCCCTCAAAGTGATGTGAGTTTAATTGTTTTAGAAAATCAAATGCCCGAA
GATTCCAGTTTGTTTTATGCTGCAGGATTTAAAATCAAAAACATTTTACTCAAAAGCGATTTATTAAATAAAAAATAA

Upstream 100 bases:

>100_bases
CCATAAACAACAAACCATAAACAACAAACTATAAACAACAAACTATAAACAATCAACCAACAACCAACAACCAACAACCA
ACAACCAACAACCAAAATAA

Downstream 100 bases:

>100_bases
ATGCAATGGCTAAAAATAAAACAACCGAAACTGAATACAGTGTAATTGATTTTATCAATGCGGTTCCTGATGAAAACAAA
CGAAATGACGCTTTTGAACT

Product: beta-lactamase

Products: A Substituted Beta- Amino Acid. [C]

Alternate protein names: FmtA-like protein [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MKFFSFTFLLFILCSCHSSAQKKDNYASKIDSIIQNSTSSDFNGVVLISKNGKTLYSKVKGSANFETQKPLTIDTQFEIM
SNSKQIAAVLVLLEAEKGRVDLNSPIKKYLPELTQTWADTVTVHQLLNHSHGIVDLQKPLAFKPGTQFKYGNLSFNLIGK
IVEFSTKKSYNETAGALFKKLKMNQTFCYSKDKAQNLATGYFSSKNKMEPVTGSQITPESFGADGIISTVSDLAIWNNNL
HKGKILKPESYKLLTKNTILSQHNFFGKEKEPYGYGIRIIEKETVKYLGHTGLGDGFSSVNLYFPQSDVSLIVLENQMPE
DSSLFYAAGFKIKNILLKSDLLNKK

Sequences:

>Translated_345_residues
MKFFSFTFLLFILCSCHSSAQKKDNYASKIDSIIQNSTSSDFNGVVLISKNGKTLYSKVKGSANFETQKPLTIDTQFEIM
SNSKQIAAVLVLLEAEKGRVDLNSPIKKYLPELTQTWADTVTVHQLLNHSHGIVDLQKPLAFKPGTQFKYGNLSFNLIGK
IVEFSTKKSYNETAGALFKKLKMNQTFCYSKDKAQNLATGYFSSKNKMEPVTGSQITPESFGADGIISTVSDLAIWNNNL
HKGKILKPESYKLLTKNTILSQHNFFGKEKEPYGYGIRIIEKETVKYLGHTGLGDGFSSVNLYFPQSDVSLIVLENQMPE
DSSLFYAAGFKIKNILLKSDLLNKK
>Mature_345_residues
MKFFSFTFLLFILCSCHSSAQKKDNYASKIDSIIQNSTSSDFNGVVLISKNGKTLYSKVKGSANFETQKPLTIDTQFEIM
SNSKQIAAVLVLLEAEKGRVDLNSPIKKYLPELTQTWADTVTVHQLLNHSHGIVDLQKPLAFKPGTQFKYGNLSFNLIGK
IVEFSTKKSYNETAGALFKKLKMNQTFCYSKDKAQNLATGYFSSKNKMEPVTGSQITPESFGADGIISTVSDLAIWNNNL
HKGKILKPESYKLLTKNTILSQHNFFGKEKEPYGYGIRIIEKETVKYLGHTGLGDGFSSVNLYFPQSDVSLIVLENQMPE
DSSLFYAAGFKIKNILLKSDLLNKK

Specific function: Its precise function is unknown. Has no penicillin- binding activity and is not involved in methicillin resistance [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790593, Length=383, Percent_Identity=23.7597911227154, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: 3.5.2.6 [C]

Molecular weight: Translated: 38560; Mature: 38560

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFFSFTFLLFILCSCHSSAQKKDNYASKIDSIIQNSTSSDFNGVVLISKNGKTLYSKVK
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEHHHHC
GSANFETQKPLTIDTQFEIMSNSKQIAAVLVLLEAEKGRVDLNSPIKKYLPELTQTWADT
CCCCCCCCCCEEECCEEEECCCCHHEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
VTVHQLLNHSHGIVDLQKPLAFKPGTQFKYGNLSFNLIGKIVEFSTKKSYNETAGALFKK
HHHHHHHCCCCCEEECCCCCCCCCCCCEEECCEEHHHHHHHHHHHCCCCCHHHHHHHHHH
LKMNQTFCYSKDKAQNLATGYFSSKNKMEPVTGSQITPESFGADGIISTVSDLAIWNNNL
HHCCCCEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHCCCC
HKGKILKPESYKLLTKNTILSQHNFFGKEKEPYGYGIRIIEKETVKYLGHTGLGDGFSSV
CCCEEECCCCCEEEEHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHCCCCCCCCCCCE
NLYFPQSDVSLIVLENQMPEDSSLFYAAGFKIKNILLKSDLLNKK
EEEECCCCCEEEEEECCCCCCCCEEEEECCEEEHHHHHHHHCCCC
>Mature Secondary Structure
MKFFSFTFLLFILCSCHSSAQKKDNYASKIDSIIQNSTSSDFNGVVLISKNGKTLYSKVK
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEHHHHC
GSANFETQKPLTIDTQFEIMSNSKQIAAVLVLLEAEKGRVDLNSPIKKYLPELTQTWADT
CCCCCCCCCCEEECCEEEECCCCHHEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
VTVHQLLNHSHGIVDLQKPLAFKPGTQFKYGNLSFNLIGKIVEFSTKKSYNETAGALFKK
HHHHHHHCCCCCEEECCCCCCCCCCCCEEECCEEHHHHHHHHHHHCCCCCHHHHHHHHHH
LKMNQTFCYSKDKAQNLATGYFSSKNKMEPVTGSQITPESFGADGIISTVSDLAIWNNNL
HHCCCCEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHCCCC
HKGKILKPESYKLLTKNTILSQHNFFGKEKEPYGYGIRIIEKETVKYLGHTGLGDGFSSV
CCCEEECCCCCEEEEHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHCCCCCCCCCCCE
NLYFPQSDVSLIVLENQMPEDSSLFYAAGFKIKNILLKSDLLNKK
EEEECCCCCEEEEEECCCCCCCCEEEEECCEEEHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Beta-Lactam; H2O [C]

Specific reaction: A Beta-Lactam + H2O = A Substituted Beta- Amino Acid. [C]

General reaction: Carboxylic acid amide hydrolysis [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA