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The map label for this gene is 146302386

Identifier: 146302386

GI number: 146302386

Start: 5635830

End: 5636603

Strand: Direct

Name: 146302386

Synonym: Fjoh_4659

Alternate gene names: NA

Gene position: 5635830-5636603 (Clockwise)

Preceding gene: 146302385

Following gene: 146302387

Centisome position: 92.44

GC content: 37.21

Gene sequence:

>774_bases
ATGAAAAATTCGATCACACTTATTTTCGCTGCAATATTGTTTTCAACTACTATGAATGCACAACTGAAACCCGTAAAATA
TTCTGAAGGAAGCCAGACTTTGAATGGTTTATTTATTAAATCGGCTAAAAAAAGCAATAATAATCCAGGAATTTTGCTTT
TACCGGCATGGCTTGGAATTGACAATGCCTCTAAAGGAATTGCCGAAGATTTATCGAAACTGGGTTACCATGTTTTTATC
GCTGATATTTATGGAGAAGGAAATTATCCAAAAAATACAGGTGAGGCTGGAAAACAAGCTGGTTTCTATAAAACAAATTA
CGAAGCGTATCAAAAACGAATTAACGCCGCTTTGCAGGAATTAGTTAAATCTGGAGCAAATGCAGATAATATCGTGGCTA
TTGGTTACTGTTTTGGAGGAACTGGAGTTCTTGAAGCAGCGCGCGGTCATTTAAACGTAAAAGGAATTGCTTCTTTTCAC
GGAGGTTTAGGAAAAGATGCTGCGAGAAAAACAGAACCTATTACAGCCAAAGTTTTAATTTGTCACGGGGCTGATGATCC
GTTTGTGCCAAAAGAAGAAATTACATCATTTCAGCAGGAAATGCGTGATTCTAAAGCTGACTGGCAGATGATTTATTATG
CCAATTCAGTACACTCATTCACAAATCCCGAAGCTGGAAACGACAATTCTAAAGGCGCTGCTTATAACCCGGTTGCTGCC
AAAAGATCTTTTGAACATTTACAGCTTTTTTTAAACGAAGTGCTTAAGAAATAA

Upstream 100 bases:

>100_bases
TCAATTTCATTCAATTTTAAGAATATAAACCTCTCAAGAAATGGCTTGAGAGGTTTTTTTGTAACATTTTATTTCAGATA
TTTGTTAAAAATTGTAAAAA

Downstream 100 bases:

>100_bases
TACTTTTTTATAGCACGCAGATGACGCTTGATTATACAAATTTGTTTAACCCGTATAATCGGCGGCCAAAAATAACCAAA
TCAAAACCAACTAAAATAAC

Product: dienelactone hydrolase

Products: 4-oxohex-2-enedioate

Alternate protein names: Dienelactone Hydrolase Family Protein; Carboxymethylenebutenolidase; Dienelactone Hydrolase Family; Hydrolase; Dienelactone Hydrolases; Dienelactone Hydrolase Protein; Dienelactone Hydrolase-Related; Transposase Remnant

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKNSITLIFAAILFSTTMNAQLKPVKYSEGSQTLNGLFIKSAKKSNNNPGILLLPAWLGIDNASKGIAEDLSKLGYHVFI
ADIYGEGNYPKNTGEAGKQAGFYKTNYEAYQKRINAALQELVKSGANADNIVAIGYCFGGTGVLEAARGHLNVKGIASFH
GGLGKDAARKTEPITAKVLICHGADDPFVPKEEITSFQQEMRDSKADWQMIYYANSVHSFTNPEAGNDNSKGAAYNPVAA
KRSFEHLQLFLNEVLKK

Sequences:

>Translated_257_residues
MKNSITLIFAAILFSTTMNAQLKPVKYSEGSQTLNGLFIKSAKKSNNNPGILLLPAWLGIDNASKGIAEDLSKLGYHVFI
ADIYGEGNYPKNTGEAGKQAGFYKTNYEAYQKRINAALQELVKSGANADNIVAIGYCFGGTGVLEAARGHLNVKGIASFH
GGLGKDAARKTEPITAKVLICHGADDPFVPKEEITSFQQEMRDSKADWQMIYYANSVHSFTNPEAGNDNSKGAAYNPVAA
KRSFEHLQLFLNEVLKK
>Mature_257_residues
MKNSITLIFAAILFSTTMNAQLKPVKYSEGSQTLNGLFIKSAKKSNNNPGILLLPAWLGIDNASKGIAEDLSKLGYHVFI
ADIYGEGNYPKNTGEAGKQAGFYKTNYEAYQKRINAALQELVKSGANADNIVAIGYCFGGTGVLEAARGHLNVKGIASFH
GGLGKDAARKTEPITAKVLICHGADDPFVPKEEITSFQQEMRDSKADWQMIYYANSVHSFTNPEAGNDNSKGAAYNPVAA
KRSFEHLQLFLNEVLKK

Specific function: Unknown

COG id: COG0412

COG function: function code Q; Dienelactone hydrolase and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Caenorhabditis elegans, GI17532655, Length=239, Percent_Identity=36.4016736401674, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17536419, Length=210, Percent_Identity=34.7619047619048, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI193204305, Length=208, Percent_Identity=30.2884615384615, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17532653, Length=225, Percent_Identity=30.6666666666667, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17536415, Length=128, Percent_Identity=38.28125, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17534829, Length=149, Percent_Identity=32.2147651006711, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.1.45

Molecular weight: Translated: 27900; Mature: 27900

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNSITLIFAAILFSTTMNAQLKPVKYSEGSQTLNGLFIKSAKKSNNNPGILLLPAWLGI
CCCCHHHHHHHHHHHHCCCCEECCEEECCCCCHHHHHEEEECCCCCCCCCEEEEEEEECC
DNASKGIAEDLSKLGYHVFIADIYGEGNYPKNTGEAGKQAGFYKTNYEAYQKRINAALQE
CCCCHHHHHHHHHCCEEEEEEEEECCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHH
LVKSGANADNIVAIGYCFGGTGVLEAARGHLNVKGIASFHGGLGKDAARKTEPITAKVLI
HHHCCCCCCCEEEEEEEECCCHHHHHHCCCCCEEEHHHHCCCCCCCHHHCCCCCEEEEEE
CHGADDPFVPKEEITSFQQEMRDSKADWQMIYYANSVHSFTNPEAGNDNSKGAAYNPVAA
EECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHH
KRSFEHLQLFLNEVLKK
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNSITLIFAAILFSTTMNAQLKPVKYSEGSQTLNGLFIKSAKKSNNNPGILLLPAWLGI
CCCCHHHHHHHHHHHHCCCCEECCEEECCCCCHHHHHEEEECCCCCCCCCEEEEEEEECC
DNASKGIAEDLSKLGYHVFIADIYGEGNYPKNTGEAGKQAGFYKTNYEAYQKRINAALQE
CCCCHHHHHHHHHCCEEEEEEEEECCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHH
LVKSGANADNIVAIGYCFGGTGVLEAARGHLNVKGIASFHGGLGKDAARKTEPITAKVLI
HHHCCCCCCCEEEEEEEECCCHHHHHHCCCCCEEEHHHHCCCCCCCHHHCCCCCEEEEEE
CHGADDPFVPKEEITSFQQEMRDSKADWQMIYYANSVHSFTNPEAGNDNSKGAAYNPVAA
EECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHH
KRSFEHLQLFLNEVLKK
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-carboxymethylenebut-2-en-4-olide; H2O

Specific reaction: 4-carboxymethylenebut-2-en-4-olide + H2O = 4-oxohex-2-enedioate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA