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The map label for this gene is csd1 [H]

Identifier: 146302382

GI number: 146302382

Start: 5630898

End: 5632832

Strand: Direct

Name: csd1 [H]

Synonym: Fjoh_4655

Alternate gene names: 146302382

Gene position: 5630898-5632832 (Clockwise)

Preceding gene: 146302381

Following gene: 146302385

Centisome position: 92.36

GC content: 39.02

Gene sequence:

>1935_bases
ATGAGTACAAATATTAACAACAACGGTTTACCAAACATCGACGATCTGCAAAATTTAGCAAACGAGTTGTTTAAAGCTTT
ACCGAATGAGTTTCCAAAAGAAATTTCATTAAGTCCGGATAAAGCCGAACATCCCCGTGCGGTAAAAATTGCAGAAACGA
TTTTACATGCCGGAAACAGTGATCAGTTTGGTCATATTCCTGCGGTGAGTCCGTCGAGTGTACCGCCGGCGCCGCCTGCA
TTCAGCGGTTTTGGAGCTTCTCCTTCTGTATCAAATTACGGCAATACTGGAGCTTCAGCTTTATACCCAAATGCCGGGGC
AGGATTTAATCCGCAAAATAGAAATTCATCTTCAGGAGTTGAGGAAAACCATGATTTAAATATGAACAATCCACATAATG
GGTTTTATGATTCAAATTTAAAAAACGGGAATTCCCCTCAATTGAATGAAGAAAGTCTTTTCTCGGTTTTTTCACTGAAC
CATCAATATCTGCCTTTTCAAGCTGAAAATTCTTCTTTTGAGATCGAATTGCAGGCGGCTTTGGCATCTGTTGATACTCA
GTTTAAAAAACGTGAAGAATTTCCTTTAAACGGAAATGAAACAGCAAATTCGTATTATTTTTTAGATCAGAATCCTTTTG
CATTTGATAAAAGAAGTACAGATCTTATAGTTGGAAATTCTTTCGATCATAAAGAGATCCAGCTTTTTAAAGGACATTAT
TTTGATGCTTCACTAGTAAAAAAGGATTTCCCGATTTTGAGAGAAACAGTAAACGGAAAGCCTTTAGTTTGGTTTGATAA
TGCGGCAACAACGCAGAAACCACAATCAGTTATTGACAGAATTGCGTATTTCTACGAACACGAAAATTCAAATATCCATC
GTGCAGCGCATGAACTGGCGGCGCGTGCCTCTGATGCGTATGAAGCGGCGCGTGAAAAAGTGAAAGCTTTTTTAAATGCC
GGTTCTGTAAATGAAATTGTTTTTGTGAGAGGCGCAACAGAAGGAATAAATCTGGTGGCTTCGACCTGGGGCGAACAGAA
TTTAAATTCAGGCGATGAAATTATTGTGAGTAATCTTGAGCATCATGCGAATATTGTTCCGTGGAAACGTCTTGCTGATA
AAAAAGGCTTAAAACTAAGAGTAATTCCTGTTGATGACGATGGTCAGATTCTGCTTGATGAATATGCAAAACTGCTCACC
TCAAAAACACGTTTGGTTGCTTTTACTCAAGTTTCAAATGCTTTAGGAACAGTAACACCTGCAAAAAAAATAGTTGAAAT
GGCACACGCTGCCGGAGCAAAAGTTTTAATTGACGGTGCACAATCGGTTTCGCATATGAAAGTCGATGTTCAGCATTTAA
ATCCAGACTGGCTGGTTTTTTCAGGACATAAATTATTTGGTCCAACGGGAATTGGAGCTTTGTACGGAAAAGAAGACTTA
CTAAACGAAATGCAGCCGTATCAATCTGGCGGCAACATGATTCAGGATGTGACTTTTGAGGAAATAAAATACCACAAAGC
ACCCAATCGTTTTGAAGCCGGAACCGGAAATATTGCCGATGCCATTGGTCTTGGCGCGGCAATAGATTATGTCACCAAAT
TAGGAATCGAAGCCATTGGTCAATACGAGCATTATTTGTTAGAATATGCCACAAGATTATTGAAAGAAATTCCGGGTGTA
CGATTGATTGGAACTGCCAAAGACAAAGCCAGTGTATTGTCTTTTAATTTACAAGGTTATTCAAACGATCAGGTGGGTCA
GGCTTTAAACAAAGAAGGTGTTGCGGTGCGAACAGGACATCATTGTGCACAGCCTATTTTAAGAAGAATGGGTGTTGAAA
CGACTGTTCGTCCGTCATTAGCATTTTATAATACAACCGAAGATGTCGATACTTTTATTAAAACCATTTGGGAACTTAAA
AAAGTGAGATTCTAA

Upstream 100 bases:

>100_bases
AAAGCCATTGCTTCGTATTTAGTATCGCTGTATTGTTCTTTGGCTATTTTAGTTGATGATGCTATTGCTGTTTTAGAAGA
TGTAGAAATAGGAAAGTATC

Downstream 100 bases:

>100_bases
AAATAAGGAGATTTTGTTCTCTCGAAATAATTACTTTTTTTGATATTTTAAGTAATTATAAACCAAAGCGATTGTTTTAG
GACAATCGCTTTTTTAATAT

Product: SufS subfamily cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 644; Mature: 643

Protein sequence:

>644_residues
MSTNINNNGLPNIDDLQNLANELFKALPNEFPKEISLSPDKAEHPRAVKIAETILHAGNSDQFGHIPAVSPSSVPPAPPA
FSGFGASPSVSNYGNTGASALYPNAGAGFNPQNRNSSSGVEENHDLNMNNPHNGFYDSNLKNGNSPQLNEESLFSVFSLN
HQYLPFQAENSSFEIELQAALASVDTQFKKREEFPLNGNETANSYYFLDQNPFAFDKRSTDLIVGNSFDHKEIQLFKGHY
FDASLVKKDFPILRETVNGKPLVWFDNAATTQKPQSVIDRIAYFYEHENSNIHRAAHELAARASDAYEAAREKVKAFLNA
GSVNEIVFVRGATEGINLVASTWGEQNLNSGDEIIVSNLEHHANIVPWKRLADKKGLKLRVIPVDDDGQILLDEYAKLLT
SKTRLVAFTQVSNALGTVTPAKKIVEMAHAAGAKVLIDGAQSVSHMKVDVQHLNPDWLVFSGHKLFGPTGIGALYGKEDL
LNEMQPYQSGGNMIQDVTFEEIKYHKAPNRFEAGTGNIADAIGLGAAIDYVTKLGIEAIGQYEHYLLEYATRLLKEIPGV
RLIGTAKDKASVLSFNLQGYSNDQVGQALNKEGVAVRTGHHCAQPILRRMGVETTVRPSLAFYNTTEDVDTFIKTIWELK
KVRF

Sequences:

>Translated_644_residues
MSTNINNNGLPNIDDLQNLANELFKALPNEFPKEISLSPDKAEHPRAVKIAETILHAGNSDQFGHIPAVSPSSVPPAPPA
FSGFGASPSVSNYGNTGASALYPNAGAGFNPQNRNSSSGVEENHDLNMNNPHNGFYDSNLKNGNSPQLNEESLFSVFSLN
HQYLPFQAENSSFEIELQAALASVDTQFKKREEFPLNGNETANSYYFLDQNPFAFDKRSTDLIVGNSFDHKEIQLFKGHY
FDASLVKKDFPILRETVNGKPLVWFDNAATTQKPQSVIDRIAYFYEHENSNIHRAAHELAARASDAYEAAREKVKAFLNA
GSVNEIVFVRGATEGINLVASTWGEQNLNSGDEIIVSNLEHHANIVPWKRLADKKGLKLRVIPVDDDGQILLDEYAKLLT
SKTRLVAFTQVSNALGTVTPAKKIVEMAHAAGAKVLIDGAQSVSHMKVDVQHLNPDWLVFSGHKLFGPTGIGALYGKEDL
LNEMQPYQSGGNMIQDVTFEEIKYHKAPNRFEAGTGNIADAIGLGAAIDYVTKLGIEAIGQYEHYLLEYATRLLKEIPGV
RLIGTAKDKASVLSFNLQGYSNDQVGQALNKEGVAVRTGHHCAQPILRRMGVETTVRPSLAFYNTTEDVDTFIKTIWELK
KVRF
>Mature_643_residues
STNINNNGLPNIDDLQNLANELFKALPNEFPKEISLSPDKAEHPRAVKIAETILHAGNSDQFGHIPAVSPSSVPPAPPAF
SGFGASPSVSNYGNTGASALYPNAGAGFNPQNRNSSSGVEENHDLNMNNPHNGFYDSNLKNGNSPQLNEESLFSVFSLNH
QYLPFQAENSSFEIELQAALASVDTQFKKREEFPLNGNETANSYYFLDQNPFAFDKRSTDLIVGNSFDHKEIQLFKGHYF
DASLVKKDFPILRETVNGKPLVWFDNAATTQKPQSVIDRIAYFYEHENSNIHRAAHELAARASDAYEAAREKVKAFLNAG
SVNEIVFVRGATEGINLVASTWGEQNLNSGDEIIVSNLEHHANIVPWKRLADKKGLKLRVIPVDDDGQILLDEYAKLLTS
KTRLVAFTQVSNALGTVTPAKKIVEMAHAAGAKVLIDGAQSVSHMKVDVQHLNPDWLVFSGHKLFGPTGIGALYGKEDLL
NEMQPYQSGGNMIQDVTFEEIKYHKAPNRFEAGTGNIADAIGLGAAIDYVTKLGIEAIGQYEHYLLEYATRLLKEIPGVR
LIGTAKDKASVLSFNLQGYSNDQVGQALNKEGVAVRTGHHCAQPILRRMGVETTVRPSLAFYNTTEDVDTFIKTIWELKK
VRF

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=411, Percent_Identity=25.7907542579075, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI156713448, Length=261, Percent_Identity=27.9693486590038, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1787970, Length=403, Percent_Identity=48.8833746898263, Blast_Score=399, Evalue=1e-112,
Organism=Escherichia coli, GI1789175, Length=396, Percent_Identity=39.3939393939394, Blast_Score=298, Evalue=8e-82,
Organism=Escherichia coli, GI48994898, Length=391, Percent_Identity=26.5984654731458, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25143064, Length=229, Percent_Identity=28.3842794759825, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI193211090, Length=358, Percent_Identity=23.1843575418994, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6319831, Length=229, Percent_Identity=31.4410480349345, Blast_Score=109, Evalue=1e-24,
Organism=Drosophila melanogaster, GI20129463, Length=415, Percent_Identity=27.710843373494, Blast_Score=124, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 70857; Mature: 70726

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNINNNGLPNIDDLQNLANELFKALPNEFPKEISLSPDKAEHPRAVKIAETILHAGNS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
DQFGHIPAVSPSSVPPAPPAFSGFGASPSVSNYGNTGASALYPNAGAGFNPQNRNSSSGV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EENHDLNMNNPHNGFYDSNLKNGNSPQLNEESLFSVFSLNHQYLPFQAENSSFEIELQAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEECCCCEEEEHHHH
LASVDTQFKKREEFPLNGNETANSYYFLDQNPFAFDKRSTDLIVGNSFDHKEIQLFKGHY
HHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCCCEEEECCCC
FDASLVKKDFPILRETVNGKPLVWFDNAATTQKPQSVIDRIAYFYEHENSNIHRAAHELA
CCHHHHHHCCHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
ARASDAYEAAREKVKAFLNAGSVNEIVFVRGATEGINLVASTWGEQNLNSGDEIIVSNLE
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHCCCCCCCCCCCCEEECCHH
HHANIVPWKRLADKKGLKLRVIPVDDDGQILLDEYAKLLTSKTRLVAFTQVSNALGTVTP
HHCCCCCHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHCCCCH
AKKIVEMAHAAGAKVLIDGAQSVSHMKVDVQHLNPDWLVFSGHKLFGPTGIGALYGKEDL
HHHHHHHHHHCCCEEEEECCCCCCEEEEEEEECCCCEEEEECCEEECCCCCCHHCCHHHH
LNEMQPYQSGGNMIQDVTFEEIKYHKAPNRFEAGTGNIADAIGLGAAIDYVTKLGIEAIG
HHHHCCHHCCCCEEHHCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QYEHYLLEYATRLLKEIPGVRLIGTAKDKASVLSFNLQGYSNDQVGQALNKEGVAVRTGH
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEECCCCCHHHHHHHCCCCCEEECCH
HCAQPILRRMGVETTVRPSLAFYNTTEDVDTFIKTIWELKKVRF
HHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STNINNNGLPNIDDLQNLANELFKALPNEFPKEISLSPDKAEHPRAVKIAETILHAGNS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
DQFGHIPAVSPSSVPPAPPAFSGFGASPSVSNYGNTGASALYPNAGAGFNPQNRNSSSGV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EENHDLNMNNPHNGFYDSNLKNGNSPQLNEESLFSVFSLNHQYLPFQAENSSFEIELQAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEECCCCEEEEHHHH
LASVDTQFKKREEFPLNGNETANSYYFLDQNPFAFDKRSTDLIVGNSFDHKEIQLFKGHY
HHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCCCEEEECCCC
FDASLVKKDFPILRETVNGKPLVWFDNAATTQKPQSVIDRIAYFYEHENSNIHRAAHELA
CCHHHHHHCCHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
ARASDAYEAAREKVKAFLNAGSVNEIVFVRGATEGINLVASTWGEQNLNSGDEIIVSNLE
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHCCCCCCCCCCCCEEECCHH
HHANIVPWKRLADKKGLKLRVIPVDDDGQILLDEYAKLLTSKTRLVAFTQVSNALGTVTP
HHCCCCCHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHCCCCH
AKKIVEMAHAAGAKVLIDGAQSVSHMKVDVQHLNPDWLVFSGHKLFGPTGIGALYGKEDL
HHHHHHHHHHCCCEEEEECCCCCCEEEEEEEECCCCEEEEECCEEECCCCCCHHCCHHHH
LNEMQPYQSGGNMIQDVTFEEIKYHKAPNRFEAGTGNIADAIGLGAAIDYVTKLGIEAIG
HHHHCCHHCCCCEEHHCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QYEHYLLEYATRLLKEIPGVRLIGTAKDKASVLSFNLQGYSNDQVGQALNKEGVAVRTGH
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEECCCCCHHHHHHHCCCCCEEECCH
HCAQPILRRMGVETTVRPSLAFYNTTEDVDTFIKTIWELKKVRF
HHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]