Click here to switch to the map view.

The map label for this gene is atsA [H]

Identifier: 146302374

GI number: 146302374

Start: 5619188

End: 5621110

Strand: Direct

Name: atsA [H]

Synonym: Fjoh_4647

Alternate gene names: 146302374

Gene position: 5619188-5621110 (Clockwise)

Preceding gene: 146302373

Following gene: 146302375

Centisome position: 92.17

GC content: 38.43

Gene sequence:

>1923_bases
ATGAAAAAAATTATGAATAACGCTGTAATTAAAAGCTCTAAAAAAGGGCTTTTAATTACTGCAATTCTGGTTGCACAACT
AGGAATTGCACAAGAAAAAGAAGAATTTAAAGGTACAATTGGCAAAACACTGGCTGATTCTAAAGAATACTGGCCAGATC
CGGTAAAAGCGCCAAAAGGCGCTCCAAACATTGTCTGGATATTATTGGATGATGTTGGATTTGGAGCTTCAAGCGCTTTT
GGAGGTTTAATCAATACGCCTACTTTTGATAATCTGGCGAATAACGGTTTACGTTATACAAACTTTCACACTACAGCTAT
TTGCGCGCCAACACGTGCTGCATTATTAACCGGAAGAAATTCTGGAAGAGTTCACGTAAGCGGTTTTTCTCACACTGTTT
TATCAGCAGGTTTTCCCGGCTGGGACGGAAGAATTCCTTCTGATAAAGGAACAATTGCCGAAATTTTACGCGACAATGGC
TATAACACTTTTGCCGTTGGTAAATATGGTGTAACTCCTGATGAAGAAGCTACAGACGCAGGACCATTTGACAGATGGCC
GACTGGAAAAGGTTTCGATCATTTTTACGGATTCCTGGGTTCGCAGACAGACCAATACAATCCTGATTTAGTGGAAGATC
AGACTCATATTAAACCTGACGGACGTCATTTAAATGAATTGATTACAGACAAAGCCATCAGCTATATTAAAACACAGCAG
AAAGCGGCGCCGGGAAAACCTTTCTTTTTATACTATGCACCGGGAGCTGTTCACGCACCTCATCAGGTAGCTGAAAAATG
GAGCGACGCATACAAAGGTAAATTTGACGAAGGTTATGATGTGTACCGCGAAAAAGTTTTAGCGAATCAAAAGAAATTAG
GAACTGTTCCGGCTAATGCTGTATTGCCAGAACGCAATCCGCTTATTACAGAATGGAAAAAATTAACTCCTGACCAAAAG
AAAGTATATGCAAGATTCATGGAAGTTTACGCCGGATTCCTGACTTATACTGATTATGAAATTGGAAGAGTGGTTAATTA
TTTAAAAGAAACCAATCAGCTTGATAATACTCTGATTTTTGTGGCAATTGGAGATAATGGAGCCAGTAAAGAAGGAACTT
TGCAGGGAACGATCAACCAGAGTTTATTTTCACAAGGAAAATCAGATGAAGAAAATCTTCAAAGCAACTTAAACAACATT
GGCGAAATTGGAACTGCAAAAGGTCTTAATACCAACTATCCTTTAGGATGGGCACAGGCTACAAACGTTCCTTTCAAAAA
CTGGAAACAAGATGCACATTCTGAAGGAGGAACACGCAATCCGCTGATTGTATTTTATCCAAACGGAATTAAAGACAAAG
GCGGTATCAGAAATCAATACAGCCACGTAACCGATTTACTGCCAACGACTTTAGATATTGCAGGAATTACTGCTCCGGAA
TATATCCGAAATATTAAACAAGATATTATTCAGGGCTCAACATTCAAAGCTTCATTGGATAATCCAAAAGCAGAATCTTT
ACACAAAGTTCAGTACTACTATATCTTTGGCAACAGAGCTATTTATAAAGACGGATGGAAAGCGGCAGCTGCACATTTAC
CAGATTCATTTGCCGTAAAACAATCATTAGGGAAAAATGAAAAACCTGCTGCAAGTAATTTTGATACTGATGTTTGGGAA
TTATACAACCTGAACGAAGATTTTAACGAACGTAACAATCTGGCTAAAAAGTATCCGGAAAAACTGGCTGAACTTCAAAA
ATTATTTGACGAACAGGCAAAAGAAAACAATGTTTATCCGTTAATTGACTGGCAGGACGTGTACAACAGAAGAATTCACA
ATACTGCTGCTGACAAAGGTAAAACATTACAGGATTTGGTAAAACAAGTAACCAAACCAGCTGATACAGGAAGCAGTAAT
TAA

Upstream 100 bases:

>100_bases
CTTTACCCTATTCCACAAAGTGAAAGAAATATTGATCCGGCAGGTTTACCGCAAAACCCTGGATATTAAACTTGAACCAT
AAACCAAAAAACTATTAAAG

Downstream 100 bases:

>100_bases
TGTATTCTTAACCTGCAGAATTAAAAGTTCTGCGGGTTAAAAATTTCTGACTTTAAACAGAATTATAAAATAAATTGCAA
AATTGGTAAAAGACACATTA

Product: sulfatase

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 640; Mature: 640

Protein sequence:

>640_residues
MKKIMNNAVIKSSKKGLLITAILVAQLGIAQEKEEFKGTIGKTLADSKEYWPDPVKAPKGAPNIVWILLDDVGFGASSAF
GGLINTPTFDNLANNGLRYTNFHTTAICAPTRAALLTGRNSGRVHVSGFSHTVLSAGFPGWDGRIPSDKGTIAEILRDNG
YNTFAVGKYGVTPDEEATDAGPFDRWPTGKGFDHFYGFLGSQTDQYNPDLVEDQTHIKPDGRHLNELITDKAISYIKTQQ
KAAPGKPFFLYYAPGAVHAPHQVAEKWSDAYKGKFDEGYDVYREKVLANQKKLGTVPANAVLPERNPLITEWKKLTPDQK
KVYARFMEVYAGFLTYTDYEIGRVVNYLKETNQLDNTLIFVAIGDNGASKEGTLQGTINQSLFSQGKSDEENLQSNLNNI
GEIGTAKGLNTNYPLGWAQATNVPFKNWKQDAHSEGGTRNPLIVFYPNGIKDKGGIRNQYSHVTDLLPTTLDIAGITAPE
YIRNIKQDIIQGSTFKASLDNPKAESLHKVQYYYIFGNRAIYKDGWKAAAAHLPDSFAVKQSLGKNEKPAASNFDTDVWE
LYNLNEDFNERNNLAKKYPEKLAELQKLFDEQAKENNVYPLIDWQDVYNRRIHNTAADKGKTLQDLVKQVTKPADTGSSN

Sequences:

>Translated_640_residues
MKKIMNNAVIKSSKKGLLITAILVAQLGIAQEKEEFKGTIGKTLADSKEYWPDPVKAPKGAPNIVWILLDDVGFGASSAF
GGLINTPTFDNLANNGLRYTNFHTTAICAPTRAALLTGRNSGRVHVSGFSHTVLSAGFPGWDGRIPSDKGTIAEILRDNG
YNTFAVGKYGVTPDEEATDAGPFDRWPTGKGFDHFYGFLGSQTDQYNPDLVEDQTHIKPDGRHLNELITDKAISYIKTQQ
KAAPGKPFFLYYAPGAVHAPHQVAEKWSDAYKGKFDEGYDVYREKVLANQKKLGTVPANAVLPERNPLITEWKKLTPDQK
KVYARFMEVYAGFLTYTDYEIGRVVNYLKETNQLDNTLIFVAIGDNGASKEGTLQGTINQSLFSQGKSDEENLQSNLNNI
GEIGTAKGLNTNYPLGWAQATNVPFKNWKQDAHSEGGTRNPLIVFYPNGIKDKGGIRNQYSHVTDLLPTTLDIAGITAPE
YIRNIKQDIIQGSTFKASLDNPKAESLHKVQYYYIFGNRAIYKDGWKAAAAHLPDSFAVKQSLGKNEKPAASNFDTDVWE
LYNLNEDFNERNNLAKKYPEKLAELQKLFDEQAKENNVYPLIDWQDVYNRRIHNTAADKGKTLQDLVKQVTKPADTGSSN
>Mature_640_residues
MKKIMNNAVIKSSKKGLLITAILVAQLGIAQEKEEFKGTIGKTLADSKEYWPDPVKAPKGAPNIVWILLDDVGFGASSAF
GGLINTPTFDNLANNGLRYTNFHTTAICAPTRAALLTGRNSGRVHVSGFSHTVLSAGFPGWDGRIPSDKGTIAEILRDNG
YNTFAVGKYGVTPDEEATDAGPFDRWPTGKGFDHFYGFLGSQTDQYNPDLVEDQTHIKPDGRHLNELITDKAISYIKTQQ
KAAPGKPFFLYYAPGAVHAPHQVAEKWSDAYKGKFDEGYDVYREKVLANQKKLGTVPANAVLPERNPLITEWKKLTPDQK
KVYARFMEVYAGFLTYTDYEIGRVVNYLKETNQLDNTLIFVAIGDNGASKEGTLQGTINQSLFSQGKSDEENLQSNLNNI
GEIGTAKGLNTNYPLGWAQATNVPFKNWKQDAHSEGGTRNPLIVFYPNGIKDKGGIRNQYSHVTDLLPTTLDIAGITAPE
YIRNIKQDIIQGSTFKASLDNPKAESLHKVQYYYIFGNRAIYKDGWKAAAAHLPDSFAVKQSLGKNEKPAASNFDTDVWE
LYNLNEDFNERNNLAKKYPEKLAELQKLFDEQAKENNVYPLIDWQDVYNRRIHNTAADKGKTLQDLVKQVTKPADTGSSN

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI109389362, Length=576, Percent_Identity=23.0902777777778, Blast_Score=104, Evalue=3e-22,
Organism=Homo sapiens, GI38569405, Length=569, Percent_Identity=22.6713532513181, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI38569407, Length=254, Percent_Identity=29.1338582677165, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI59797060, Length=222, Percent_Identity=29.7297297297297, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI4503899, Length=439, Percent_Identity=25.5125284738041, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI157266309, Length=476, Percent_Identity=24.7899159663866, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI53831991, Length=139, Percent_Identity=35.2517985611511, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI146229331, Length=243, Percent_Identity=30.8641975308642, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI146229329, Length=243, Percent_Identity=30.8641975308642, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI6005990, Length=243, Percent_Identity=30.8641975308642, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI146229324, Length=243, Percent_Identity=30.8641975308642, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI71852586, Length=163, Percent_Identity=34.9693251533742, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI71852584, Length=163, Percent_Identity=34.9693251533742, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI31742482, Length=155, Percent_Identity=34.1935483870968, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI45430057, Length=272, Percent_Identity=27.5735294117647, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI58743319, Length=138, Percent_Identity=31.8840579710145, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI87081924, Length=651, Percent_Identity=22.1198156682028, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790233, Length=505, Percent_Identity=23.5643564356436, Blast_Score=70, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI115533416, Length=450, Percent_Identity=26.2222222222222, Blast_Score=102, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI115533418, Length=444, Percent_Identity=25.9009009009009, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17559078, Length=136, Percent_Identity=32.3529411764706, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24666175, Length=601, Percent_Identity=24.2928452579035, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI281363223, Length=493, Percent_Identity=24.3407707910751, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281366397, Length=441, Percent_Identity=24.4897959183673, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI281366395, Length=441, Percent_Identity=24.4897959183673, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24666163, Length=441, Percent_Identity=24.4897959183673, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24666109, Length=432, Percent_Identity=24.7685185185185, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24653364, Length=315, Percent_Identity=26.3492063492064, Blast_Score=81, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19922168, Length=315, Percent_Identity=26.031746031746, Blast_Score=78, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 71039; Mature: 71039

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: PS00523 SULFATASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIMNNAVIKSSKKGLLITAILVAQLGIAQEKEEFKGTIGKTLADSKEYWPDPVKAPKG
CCHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCC
APNIVWILLDDVGFGASSAFGGLINTPTFDNLANNGLRYTNFHTTAICAPTRAALLTGRN
CCCEEEEEEECCCCCCHHHCCCCCCCCCHHHHHCCCCEEEEECEEEEECCCHHHEEECCC
SGRVHVSGFSHTVLSAGFPGWDGRIPSDKGTIAEILRDNGYNTFAVGKYGVTPDEEATDA
CCEEEECCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCC
GPFDRWPTGKGFDHFYGFLGSQTDQYNPDLVEDQTHIKPDGRHLNELITDKAISYIKTQQ
CCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KAAPGKPFFLYYAPGAVHAPHQVAEKWSDAYKGKFDEGYDVYREKVLANQKKLGTVPANA
HCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
VLPERNPLITEWKKLTPDQKKVYARFMEVYAGFLTYTDYEIGRVVNYLKETNQLDNTLIF
CCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEE
VAIGDNGASKEGTLQGTINQSLFSQGKSDEENLQSNLNNIGEIGTAKGLNTNYPLGWAQA
EEECCCCCCCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHC
TNVPFKNWKQDAHSEGGTRNPLIVFYPNGIKDKGGIRNQYSHVTDLLPTTLDIAGITAPE
CCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHH
YIRNIKQDIIQGSTFKASLDNPKAESLHKVQYYYIFGNRAIYKDGWKAAAAHLPDSFAVK
HHHHHHHHHHCCCCEEECCCCCCHHHHEEEEEEEEECCEEEECCCHHHHHHHCCCHHHHH
QSLGKNEKPAASNFDTDVWELYNLNEDFNERNNLAKKYPEKLAELQKLFDEQAKENNVYP
HHCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LIDWQDVYNRRIHNTAADKGKTLQDLVKQVTKPADTGSSN
EECHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKKIMNNAVIKSSKKGLLITAILVAQLGIAQEKEEFKGTIGKTLADSKEYWPDPVKAPKG
CCHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCC
APNIVWILLDDVGFGASSAFGGLINTPTFDNLANNGLRYTNFHTTAICAPTRAALLTGRN
CCCEEEEEEECCCCCCHHHCCCCCCCCCHHHHHCCCCEEEEECEEEEECCCHHHEEECCC
SGRVHVSGFSHTVLSAGFPGWDGRIPSDKGTIAEILRDNGYNTFAVGKYGVTPDEEATDA
CCEEEECCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCC
GPFDRWPTGKGFDHFYGFLGSQTDQYNPDLVEDQTHIKPDGRHLNELITDKAISYIKTQQ
CCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KAAPGKPFFLYYAPGAVHAPHQVAEKWSDAYKGKFDEGYDVYREKVLANQKKLGTVPANA
HCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
VLPERNPLITEWKKLTPDQKKVYARFMEVYAGFLTYTDYEIGRVVNYLKETNQLDNTLIF
CCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEE
VAIGDNGASKEGTLQGTINQSLFSQGKSDEENLQSNLNNIGEIGTAKGLNTNYPLGWAQA
EEECCCCCCCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHC
TNVPFKNWKQDAHSEGGTRNPLIVFYPNGIKDKGGIRNQYSHVTDLLPTTLDIAGITAPE
CCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHH
YIRNIKQDIIQGSTFKASLDNPKAESLHKVQYYYIFGNRAIYKDGWKAAAAHLPDSFAVK
HHHHHHHHHHCCCCEEECCCCCCHHHHEEEEEEEEECCEEEECCCHHHHHHHCCCHHHHH
QSLGKNEKPAASNFDTDVWELYNLNEDFNERNNLAKKYPEKLAELQKLFDEQAKENNVYP
HHCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LIDWQDVYNRRIHNTAADKGKTLQDLVKQVTKPADTGSSN
EECHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7744061; 10984043 [H]