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The map label for this gene is catR [H]

Identifier: 146302348

GI number: 146302348

Start: 5584434

End: 5585321

Strand: Direct

Name: catR [H]

Synonym: Fjoh_4621

Alternate gene names: 146302348

Gene position: 5584434-5585321 (Clockwise)

Preceding gene: 146302346

Following gene: 146302349

Centisome position: 91.6

GC content: 32.09

Gene sequence:

>888_bases
ATGGAATTACGTCACCTAAAATATTTTATGGCTGTAGCCGAAGAACTAAACTTTACCAAAGCATCAGAAAAACTGTTTAT
CTCACAGCCTCCGTTGAGTCGGCAGATTGCTGAATTGGAAGACGAACTTCAGGCAAAACTTTTCATAAGAAACAATAAAA
AGGTAGAATTGACCGAAGCCGGGAAATATTTCGAAAAAGAAGTAATAGAACTTTTTCAGAATCTGGAACGTATTTCTATT
AAAACAAAAAAGATTGCAGAAAATGTTTCGGGTGAATTTAGAATCGCTTATATAAGCTCTATATATTCTTCTATTATTTC
AGATTTAATCAAACACCTCAAATCACAGTTTCCGTACGTAAATTTTAAACTTTTTGAAATTTCAACCACCAAACAAATCG
ATGCTTTAGAACAAGGAAAAATCGAAATGGGAATTATTCGATCACCAATTCAGTCACCAAAAATAAAATCACATCTGTGG
TTTAAAGATGGTTTTTCATTGGTTTACAACAAAAAATCCGTTCAGATAAAATCAGAAAATGAAATTGCAAACCTAAAAGA
CGAAACATTTGTTTTCTTCAACAAAGATTATGCACCTCATTATCACGAAGTTTTATTAGAGCTTTGTGCTTTTTATGGCT
TTACTCCGCAGATTATTCACGAAGCCAATAACATCAATTCCATCGTACAATTAGTCAAAAACGGATTAGGAATTTCGATT
GTTCCTTCAAACGTTGCCAAAAACAATCAGGATCCAGAAATTGGTTTTATTGAACTGAAAAAGGTTAATTTAAAAACAGA
TGTTTCGATTATCACATCCAAAGAAGATGAATCTGAAATCACGAAATCTGCTGTTGATTTTTTGTTGATGAAGAATAATT
CTCGATAA

Upstream 100 bases:

>100_bases
ATATCTGCGAGAGACTTATTTTTTGATTTTTCAAAACTATTCTTTTCTTAAATACTTTAAAAATACTATTTTTATCAATT
AATAATACTTTAAAAGTATC

Downstream 100 bases:

>100_bases
GTTTTGATTTTTTAATCTCGCAAAGACGCGAAGTCGCAAAGTTTTTATTTATAAGTTGCGTCCAGCTTTAGCTGGATGAG
AAAATAACTACGTTTAAAAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: CatBC operon transcriptional activator [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MELRHLKYFMAVAEELNFTKASEKLFISQPPLSRQIAELEDELQAKLFIRNNKKVELTEAGKYFEKEVIELFQNLERISI
KTKKIAENVSGEFRIAYISSIYSSIISDLIKHLKSQFPYVNFKLFEISTTKQIDALEQGKIEMGIIRSPIQSPKIKSHLW
FKDGFSLVYNKKSVQIKSENEIANLKDETFVFFNKDYAPHYHEVLLELCAFYGFTPQIIHEANNINSIVQLVKNGLGISI
VPSNVAKNNQDPEIGFIELKKVNLKTDVSIITSKEDESEITKSAVDFLLMKNNSR

Sequences:

>Translated_295_residues
MELRHLKYFMAVAEELNFTKASEKLFISQPPLSRQIAELEDELQAKLFIRNNKKVELTEAGKYFEKEVIELFQNLERISI
KTKKIAENVSGEFRIAYISSIYSSIISDLIKHLKSQFPYVNFKLFEISTTKQIDALEQGKIEMGIIRSPIQSPKIKSHLW
FKDGFSLVYNKKSVQIKSENEIANLKDETFVFFNKDYAPHYHEVLLELCAFYGFTPQIIHEANNINSIVQLVKNGLGISI
VPSNVAKNNQDPEIGFIELKKVNLKTDVSIITSKEDESEITKSAVDFLLMKNNSR
>Mature_295_residues
MELRHLKYFMAVAEELNFTKASEKLFISQPPLSRQIAELEDELQAKLFIRNNKKVELTEAGKYFEKEVIELFQNLERISI
KTKKIAENVSGEFRIAYISSIYSSIISDLIKHLKSQFPYVNFKLFEISTTKQIDALEQGKIEMGIIRSPIQSPKIKSHLW
FKDGFSLVYNKKSVQIKSENEIANLKDETFVFFNKDYAPHYHEVLLELCAFYGFTPQIIHEANNINSIVQLVKNGLGISI
VPSNVAKNNQDPEIGFIELKKVNLKTDVSIITSKEDESEITKSAVDFLLMKNNSR

Specific function: Positive regulator of the catBC operon that degrades catechol to acetyl-CoA. CatR binds in trans to the catR-catBC promoter-control region in the presence or absence of inducer but only activates the catBC operon in the presence of the inducer, cis-cis-mu

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=286, Percent_Identity=31.4685314685315, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI157672245, Length=247, Percent_Identity=28.3400809716599, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788887, Length=245, Percent_Identity=31.0204081632653, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI2367136, Length=289, Percent_Identity=28.3737024221453, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788297, Length=255, Percent_Identity=27.0588235294118, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788748, Length=241, Percent_Identity=24.4813278008299, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790399, Length=244, Percent_Identity=24.1803278688525, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1790208, Length=258, Percent_Identity=24.8062015503876, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787601, Length=145, Percent_Identity=29.6551724137931, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787806, Length=248, Percent_Identity=22.1774193548387, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1789204, Length=241, Percent_Identity=22.8215767634855, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1789506, Length=252, Percent_Identity=23.015873015873, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788481, Length=247, Percent_Identity=22.2672064777328, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789173, Length=122, Percent_Identity=31.1475409836066, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI145693105, Length=144, Percent_Identity=27.0833333333333, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788296, Length=238, Percent_Identity=24.3697478991597, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33935; Mature: 33935

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRHLKYFMAVAEELNFTKASEKLFISQPPLSRQIAELEDELQAKLFIRNNKKVELTEA
CCHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHEEEEEECCCEEEEHHH
GKYFEKEVIELFQNLERISIKTKKIAENVSGEFRIAYISSIYSSIISDLIKHLKSQFPYV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCEE
NFKLFEISTTKQIDALEQGKIEMGIIRSPIQSPKIKSHLWFKDGFSLVYNKKSVQIKSEN
EEEEEEECCCHHHHHHHCCCEEEHHHHCCCCCCCCCCEEEECCCCEEEEECCEEEEECCC
EIANLKDETFVFFNKDYAPHYHEVLLELCAFYGFTPQIIHEANNINSIVQLVKNGLGISI
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHCCCCEEE
VPSNVAKNNQDPEIGFIELKKVNLKTDVSIITSKEDESEITKSAVDFLLMKNNSR
ECCHHHCCCCCCCEEEEEEEEECCEECEEEEECCCCHHHHHHHHHHEEEEECCCC
>Mature Secondary Structure
MELRHLKYFMAVAEELNFTKASEKLFISQPPLSRQIAELEDELQAKLFIRNNKKVELTEA
CCHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHEEEEEECCCEEEEHHH
GKYFEKEVIELFQNLERISIKTKKIAENVSGEFRIAYISSIYSSIISDLIKHLKSQFPYV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCEE
NFKLFEISTTKQIDALEQGKIEMGIIRSPIQSPKIKSHLWFKDGFSLVYNKKSVQIKSEN
EEEEEEECCCHHHHHHHCCCEEEHHHHCCCCCCCCCCEEEECCCCEEEEECCEEEEECCC
EIANLKDETFVFFNKDYAPHYHEVLLELCAFYGFTPQIIHEANNINSIVQLVKNGLGISI
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHCCCCEEE
VPSNVAKNNQDPEIGFIELKKVNLKTDVSIITSKEDESEITKSAVDFLLMKNNSR
ECCHHHCCCCCCCEEEEEEEEECCEECEEEEECCCCHHHHHHHHHHEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1688844 [H]