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The map label for this gene is aphA [H]

Identifier: 146302208

GI number: 146302208

Start: 5401728

End: 5403236

Strand: Direct

Name: aphA [H]

Synonym: Fjoh_4479

Alternate gene names: 146302208

Gene position: 5401728-5403236 (Clockwise)

Preceding gene: 146302207

Following gene: 146302209

Centisome position: 88.6

GC content: 32.87

Gene sequence:

>1509_bases
ATGTATGATTATGTATCGCTGTTAAAAAACATTGTGGACAACACACCTCTTCCAATAGCTGTTTTAATTGGTCCCGAACT
TAAAATAGAGCTTGCTAATCCTGCAATGATTTCCGTATGGGGAAAAGGAAACGAGGTAATCGGAAAAAACTATTTTGACG
TAATTCCTGAATCTCCCAGACACGAAATAATGACGCAGGCTCTTGAAGTATTAAACACAGGAATACCATTTTATGCAAAG
GATAAATTGATAGATTTAATAGTTGATGGAAAAATAACACACCATTATTTTAACTACAGTTTTACTCCTCTTTATGGTAA
AGATGGAAAAATTTACGGTCTGCTAAAAAATGGAACCGATATAACAGACATGCACAACATAAAGCAGAAGATACAAAGTG
CAGACGAAAGACTCCGCATAGCAGTTGAATCTTCCGGAATGGGAACTTACGAAATAAATTTAATTACTAAGGAAACTGTT
ACTTCTGGAAATTTTAATGAATTATGGTCAGTTGATGACGCGTCAGATACTGAAATGCTTCTAAAAAAAATGCATCCTGA
AGATTTACCAGTAAGAGAAAAAGCACATCAGGACGCATTAATTACAGGAAAAATAGTGTATGAAGCAAGGATTATAAATG
ATAATCAATCTGAAAAATGGGTAAAAGTCAACGGTAAAATTATAAAAGATCAAAATGGGAATGCTTCCAGCATCATTGGA
ATTATACAGGATATCAGCGATCAGAGGCAGTTTGAAAAAGAGCTTCAGGAAAAAATCAAGGAAAACACTAAAGAGCTTAG
AAAGTCAAACGAGAATCTAATTCATTTCGCCAATATGGTTACTCATGACTTAAAAGAGCCTGTAAGAAAAATTAAAACTT
TTAATGGTTTATTAAAAAAAGAAATTGAATCTGAAAGAATTGAAAATATAAAAAAATATAGTGATAAAGTGGATCAGTCT
GCCCAAAGAATGCAGACATTAATAGAAGGTACACTAGCCTATTCAACTCTTAACAAATCAATTCAGCCAGTCCAGAAAAT
AAATCTGGATGAGATAGTTGAAAATATAAAAATCGATCTAGAACTTATTATACAAGAAAAGAATGCTATTCTTATTACAA
GTGAACTTCCTGAAATAGAAGGAGCTCCAATATTAATACACCAGTTATTTTATAATTTAATACACAATGCTTTAAAATTT
TCCAAAGCAGATGAACCGCCCAGAGTTGTAATAACATCGAATATTTTAGATAAAAATGGTACAAAACATGTTCAGATAAT
CATTAAAGATAATGGTATTGGACTCGATGATATTTATGCAGATCGTATATTCAATGCTTTTGAGAGACTGCATTCCAAAG
ATGATTATGAAGGAACCGGCCTGGGACTTGCCCTATGCAGAAAAATAACAGAAAGACATTATGGAACTATCAATGCTGCA
GGAAAAGAAAATGATGGTGCCGAATTTACAGTCACTCTGCCGCTAATCCAGGAAAAAAAGATTATCTAA

Upstream 100 bases:

>100_bases
ATAGTTGAATTATTCATTGAAATTATGAAATATTAGCCAGTCTTGATATAACATCTACACTTTGTTTGATTCTAAATTTG
TAAACAAAAAAATATCCGCC

Downstream 100 bases:

>100_bases
CAGTTTGACTGGTAGAGTAAATTTGATAAAAAACACAAGAACATTCTAAAAGACTTTATCACAACAAACCCAAAGCTGTT
CGAAACCGCTTCAATAGAAT

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MYDYVSLLKNIVDNTPLPIAVLIGPELKIELANPAMISVWGKGNEVIGKNYFDVIPESPRHEIMTQALEVLNTGIPFYAK
DKLIDLIVDGKITHHYFNYSFTPLYGKDGKIYGLLKNGTDITDMHNIKQKIQSADERLRIAVESSGMGTYEINLITKETV
TSGNFNELWSVDDASDTEMLLKKMHPEDLPVREKAHQDALITGKIVYEARIINDNQSEKWVKVNGKIIKDQNGNASSIIG
IIQDISDQRQFEKELQEKIKENTKELRKSNENLIHFANMVTHDLKEPVRKIKTFNGLLKKEIESERIENIKKYSDKVDQS
AQRMQTLIEGTLAYSTLNKSIQPVQKINLDEIVENIKIDLELIIQEKNAILITSELPEIEGAPILIHQLFYNLIHNALKF
SKADEPPRVVITSNILDKNGTKHVQIIIKDNGIGLDDIYADRIFNAFERLHSKDDYEGTGLGLALCRKITERHYGTINAA
GKENDGAEFTVTLPLIQEKKII

Sequences:

>Translated_502_residues
MYDYVSLLKNIVDNTPLPIAVLIGPELKIELANPAMISVWGKGNEVIGKNYFDVIPESPRHEIMTQALEVLNTGIPFYAK
DKLIDLIVDGKITHHYFNYSFTPLYGKDGKIYGLLKNGTDITDMHNIKQKIQSADERLRIAVESSGMGTYEINLITKETV
TSGNFNELWSVDDASDTEMLLKKMHPEDLPVREKAHQDALITGKIVYEARIINDNQSEKWVKVNGKIIKDQNGNASSIIG
IIQDISDQRQFEKELQEKIKENTKELRKSNENLIHFANMVTHDLKEPVRKIKTFNGLLKKEIESERIENIKKYSDKVDQS
AQRMQTLIEGTLAYSTLNKSIQPVQKINLDEIVENIKIDLELIIQEKNAILITSELPEIEGAPILIHQLFYNLIHNALKF
SKADEPPRVVITSNILDKNGTKHVQIIIKDNGIGLDDIYADRIFNAFERLHSKDDYEGTGLGLALCRKITERHYGTINAA
GKENDGAEFTVTLPLIQEKKII
>Mature_502_residues
MYDYVSLLKNIVDNTPLPIAVLIGPELKIELANPAMISVWGKGNEVIGKNYFDVIPESPRHEIMTQALEVLNTGIPFYAK
DKLIDLIVDGKITHHYFNYSFTPLYGKDGKIYGLLKNGTDITDMHNIKQKIQSADERLRIAVESSGMGTYEINLITKETV
TSGNFNELWSVDDASDTEMLLKKMHPEDLPVREKAHQDALITGKIVYEARIINDNQSEKWVKVNGKIIKDQNGNASSIIG
IIQDISDQRQFEKELQEKIKENTKELRKSNENLIHFANMVTHDLKEPVRKIKTFNGLLKKEIESERIENIKKYSDKVDQS
AQRMQTLIEGTLAYSTLNKSIQPVQKINLDEIVENIKIDLELIIQEKNAILITSELPEIEGAPILIHQLFYNLIHNALKF
SKADEPPRVVITSNILDKNGTKHVQIIIKDNGIGLDDIYADRIFNAFERLHSKDDYEGTGLGLALCRKITERHYGTINAA
GKENDGAEFTVTLPLIQEKKII

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=271, Percent_Identity=23.2472324723247, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790436, Length=360, Percent_Identity=23.3333333333333, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786912, Length=217, Percent_Identity=27.1889400921659, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788713, Length=275, Percent_Identity=26.9090909090909, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790346, Length=224, Percent_Identity=24.5535714285714, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789149, Length=276, Percent_Identity=24.6376811594203, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI48994928, Length=276, Percent_Identity=22.1014492753623, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1790861, Length=207, Percent_Identity=25.1207729468599, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1786783, Length=234, Percent_Identity=23.9316239316239, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56928; Mature: 56928

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDYVSLLKNIVDNTPLPIAVLIGPELKIELANPAMISVWGKGNEVIGKNYFDVIPESPR
CCHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCEEEEEECCCCCCCCCCHHHCCCCCCH
HEIMTQALEVLNTGIPFYAKDKLIDLIVDGKITHHYFNYSFTPLYGKDGKIYGLLKNGTD
HHHHHHHHHHHHCCCCCEECCCEEEEEECCEEEEEEECEEEEEEECCCCCEEEEEECCCC
ITDMHNIKQKIQSADERLRIAVESSGMGTYEINLITKETVTSGNFNELWSVDDASDTEML
CHHHHHHHHHHHCHHHHEEEEEECCCCCEEEEEEEEECEECCCCCHHCCCCCCCCHHHHH
LKKMHPEDLPVREKAHQDALITGKIVYEARIINDNQSEKWVKVNGKIIKDQNGNASSIIG
HHHCCCCCCCCHHHHCCCCEEEEEEEEEEEEECCCCCCCEEEECCEEEECCCCCHHHHHH
IIQDISDQRQFEKELQEKIKENTKELRKSNENLIHFANMVTHDLKEPVRKIKTFNGLLKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHH
EIESERIENIKKYSDKVDQSAQRMQTLIEGTLAYSTLNKSIQPVQKINLDEIVENIKIDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHEEEE
ELIIQEKNAILITSELPEIEGAPILIHQLFYNLIHNALKFSKADEPPRVVITSNILDKNG
EEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCC
TKHVQIIIKDNGIGLDDIYADRIFNAFERLHSKDDYEGTGLGLALCRKITERHYGTINAA
CEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEECC
GKENDGAEFTVTLPLIQEKKII
CCCCCCCEEEEEEEECCCCCCC
>Mature Secondary Structure
MYDYVSLLKNIVDNTPLPIAVLIGPELKIELANPAMISVWGKGNEVIGKNYFDVIPESPR
CCHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCEEEEEECCCCCCCCCCHHHCCCCCCH
HEIMTQALEVLNTGIPFYAKDKLIDLIVDGKITHHYFNYSFTPLYGKDGKIYGLLKNGTD
HHHHHHHHHHHHCCCCCEECCCEEEEEECCEEEEEEECEEEEEEECCCCCEEEEEECCCC
ITDMHNIKQKIQSADERLRIAVESSGMGTYEINLITKETVTSGNFNELWSVDDASDTEML
CHHHHHHHHHHHCHHHHEEEEEECCCCCEEEEEEEEECEECCCCCHHCCCCCCCCHHHHH
LKKMHPEDLPVREKAHQDALITGKIVYEARIINDNQSEKWVKVNGKIIKDQNGNASSIIG
HHHCCCCCCCCHHHHCCCCEEEEEEEEEEEEECCCCCCCEEEECCEEEECCCCCHHHHHH
IIQDISDQRQFEKELQEKIKENTKELRKSNENLIHFANMVTHDLKEPVRKIKTFNGLLKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHH
EIESERIENIKKYSDKVDQSAQRMQTLIEGTLAYSTLNKSIQPVQKINLDEIVENIKIDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHEEEE
ELIIQEKNAILITSELPEIEGAPILIHQLFYNLIHNALKFSKADEPPRVVITSNILDKNG
EEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCC
TKHVQIIIKDNGIGLDDIYADRIFNAFERLHSKDDYEGTGLGLALCRKITERHYGTINAA
CEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEECC
GKENDGAEFTVTLPLIQEKKII
CCCCCCCEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]