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The map label for this gene is fabF [H]

Identifier: 146302049

GI number: 146302049

Start: 5209596

End: 5211398

Strand: Direct

Name: fabF [H]

Synonym: Fjoh_4313

Alternate gene names: 146302049

Gene position: 5209596-5211398 (Clockwise)

Preceding gene: 146302048

Following gene: 146302050

Centisome position: 85.45

GC content: 36.38

Gene sequence:

>1803_bases
ATGACAACACGTGAAAATATTATAGATAAAGCAGATCAATTTATTCGAAACAAAGGCTACAATGCCTTTAGTTTTAAAGA
TATTTCAAATGATATAGGCATAAAAACCGCTTCTATACATTACCACTTCCCTACAAAATCAGATCTTGGTGTAGCGACTA
TTAAAGAACATATTGCCAGATATGAAGTTTTAAAAAAAAAGGTTGCTAACGAATCTCCATTAATAAAATTAGAATCTTTT
TTAGCTGTTCATACACAAATTAAACATGAAAATAAAGTCTGCATTGTTGGATCGCTGGCAACAGACTTAAATACACTAGA
TGAATCAATAAAAGACGAACTAAAAATATTTGCCAAATTGGTGATTGACTGGCTGACTGAAGTTCTGACTGAAGGGAAAG
AACAAAATATATTTGATTTTCAAACTTCTGCAAGAACAAAAGCATTAATGATAATAACCAATATGGTAGCAATAGTCCAG
CTTTCAAGACTAACAAACGATGATGATTTTGAATTGGTAAGAGAAACAATATTAACAGAATTAAGACCTAAAAAAATAAT
GAAAAGAGTTGTAGTAACAGGCTTAGGAGCAGTAACTCCTATTGGCAATAATGTTCAGGAATATTGGAATTCATTAATTA
ACGGAGTAAGCGGTGCCGCTCCCATAACAAGATTTGACACCACACAATTTAAAACCAAATTTGCCTGCGAAGTTAAAAAC
TTCGATGCTTCGCCTATTTTTGAAAAAAATGAAATTAGAAAATATGATCTTTTTACACAATATGCTCTGCATGCAGCAGA
CGAAGCTGTAAAAAATGCCAATATTGATTTTGATACCTTAAATAAAAACCGAATTGGAGTAATCTGGGGATGCGGCGATG
GCGGTATTTCTACTTTTGAAGAACAATTTGGAGAATATAAATTAGGAAACGGCACACCAAGATTTAGTCCGTTTTTTATT
CCGAAAAGAATTGTCAATATTGCTTCAGGTGTTATTTCTATTAAATATGGTCTTCGCGGTATTAACTATACAACAGCTGC
TGCCTGCTCTGCCAGTAATACTGCCATTATCGATGCCTTTAACTACATTCGCTGGGGCAAAGCAGATATGATTATCAGCG
GCGGTTCTGAAGCCTCAGTTTCAGAATCTTCAATTGGAGGTTTCAATGCTTCAAAAGCACTGTCAACTTTAAACGAAGAT
CATAGCAAAGCTTCTCGTCCTTTTGATGTTACAAGAGATGGATTTGTTTTAGGAGAAGGTGCTGGAGTTGTTATCTTAGA
AAGCTACGAACATGCAGTAAAACGAAATGCCGTAATCCTGGCCGAAATTGTGGGCGGAGGTTTAGCGGCAGACGCTTATC
ACTTAACAGGAACACACCCTGAAGGCGAAGGCGCTGTTTTAGGTATGGAACTTGCTCTTGAGGAAGCCGGAATTACTCCG
GATAAAATTGACTATATCAATGCTCACGCTACCTCTACTCCAGCGGGTGACTTAAGCGAACTAAAAGCAATAGAAAAAGT
ATTTGGAATAAATCCTAATGCAAACATTAGTGCTACAAAATCAATGACCGGGCATTTACTTGGAGGCGCGGGAGCAATCG
AAGCAGTTGCTTGTATAAAAGCGCTTCAGGAAAACATTGTACCGCCAACTATAAATACACAAACAATTGAACAGGATTAT
GCTGAAAAATTTAATCTGACTCTTGGAAAAGCGCAGGCAAGAGAAGTGAATTATGCCATGAGCAATACTTTTGGTTTTGG
CGGACACGTAGCCAGTTCGATCTTTAAAAAATTTAAAGAATAA

Upstream 100 bases:

>100_bases
TCCCTTTCTTAATGAAAGGGATTTTTTGTTTTGTTAAAAATAAACAAAATAAATTTGCCTATCTACTAATAGGTAGTATA
TTTGCTAAAAAATTACTGCG

Downstream 100 bases:

>100_bases
ACAATTATAACATATTTATTAATAAAAAGAGCTGTCTCAAAAATTGAGACAGCTCTTTTTATTTTTTTTAAGCACTCGTA
CAACGCAGCATTTATACAAA

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 600; Mature: 599

Protein sequence:

>600_residues
MTTRENIIDKADQFIRNKGYNAFSFKDISNDIGIKTASIHYHFPTKSDLGVATIKEHIARYEVLKKKVANESPLIKLESF
LAVHTQIKHENKVCIVGSLATDLNTLDESIKDELKIFAKLVIDWLTEVLTEGKEQNIFDFQTSARTKALMIITNMVAIVQ
LSRLTNDDDFELVRETILTELRPKKIMKRVVVTGLGAVTPIGNNVQEYWNSLINGVSGAAPITRFDTTQFKTKFACEVKN
FDASPIFEKNEIRKYDLFTQYALHAADEAVKNANIDFDTLNKNRIGVIWGCGDGGISTFEEQFGEYKLGNGTPRFSPFFI
PKRIVNIASGVISIKYGLRGINYTTAAACSASNTAIIDAFNYIRWGKADMIISGGSEASVSESSIGGFNASKALSTLNED
HSKASRPFDVTRDGFVLGEGAGVVILESYEHAVKRNAVILAEIVGGGLAADAYHLTGTHPEGEGAVLGMELALEEAGITP
DKIDYINAHATSTPAGDLSELKAIEKVFGINPNANISATKSMTGHLLGGAGAIEAVACIKALQENIVPPTINTQTIEQDY
AEKFNLTLGKAQAREVNYAMSNTFGFGGHVASSIFKKFKE

Sequences:

>Translated_600_residues
MTTRENIIDKADQFIRNKGYNAFSFKDISNDIGIKTASIHYHFPTKSDLGVATIKEHIARYEVLKKKVANESPLIKLESF
LAVHTQIKHENKVCIVGSLATDLNTLDESIKDELKIFAKLVIDWLTEVLTEGKEQNIFDFQTSARTKALMIITNMVAIVQ
LSRLTNDDDFELVRETILTELRPKKIMKRVVVTGLGAVTPIGNNVQEYWNSLINGVSGAAPITRFDTTQFKTKFACEVKN
FDASPIFEKNEIRKYDLFTQYALHAADEAVKNANIDFDTLNKNRIGVIWGCGDGGISTFEEQFGEYKLGNGTPRFSPFFI
PKRIVNIASGVISIKYGLRGINYTTAAACSASNTAIIDAFNYIRWGKADMIISGGSEASVSESSIGGFNASKALSTLNED
HSKASRPFDVTRDGFVLGEGAGVVILESYEHAVKRNAVILAEIVGGGLAADAYHLTGTHPEGEGAVLGMELALEEAGITP
DKIDYINAHATSTPAGDLSELKAIEKVFGINPNANISATKSMTGHLLGGAGAIEAVACIKALQENIVPPTINTQTIEQDY
AEKFNLTLGKAQAREVNYAMSNTFGFGGHVASSIFKKFKE
>Mature_599_residues
TTRENIIDKADQFIRNKGYNAFSFKDISNDIGIKTASIHYHFPTKSDLGVATIKEHIARYEVLKKKVANESPLIKLESFL
AVHTQIKHENKVCIVGSLATDLNTLDESIKDELKIFAKLVIDWLTEVLTEGKEQNIFDFQTSARTKALMIITNMVAIVQL
SRLTNDDDFELVRETILTELRPKKIMKRVVVTGLGAVTPIGNNVQEYWNSLINGVSGAAPITRFDTTQFKTKFACEVKNF
DASPIFEKNEIRKYDLFTQYALHAADEAVKNANIDFDTLNKNRIGVIWGCGDGGISTFEEQFGEYKLGNGTPRFSPFFIP
KRIVNIASGVISIKYGLRGINYTTAAACSASNTAIIDAFNYIRWGKADMIISGGSEASVSESSIGGFNASKALSTLNEDH
SKASRPFDVTRDGFVLGEGAGVVILESYEHAVKRNAVILAEIVGGGLAADAYHLTGTHPEGEGAVLGMELALEEAGITPD
KIDYINAHATSTPAGDLSELKAIEKVFGINPNANISATKSMTGHLLGGAGAIEAVACIKALQENIVPPTINTQTIEQDYA
EKFNLTLGKAQAREVNYAMSNTFGFGGHVASSIFKKFKE

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=415, Percent_Identity=39.5180722891566, Blast_Score=280, Evalue=3e-75,
Organism=Homo sapiens, GI223972627, Length=171, Percent_Identity=42.1052631578947, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI41872631, Length=419, Percent_Identity=24.3436754176611, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI1787337, Length=416, Percent_Identity=45.9134615384615, Blast_Score=324, Evalue=1e-89,
Organism=Escherichia coli, GI1788663, Length=418, Percent_Identity=37.0813397129187, Blast_Score=237, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI71983541, Length=423, Percent_Identity=34.9881796690307, Blast_Score=224, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI71983535, Length=268, Percent_Identity=38.8059701492537, Blast_Score=176, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI212642053, Length=428, Percent_Identity=24.5327102803738, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17550940, Length=425, Percent_Identity=23.2941176470588, Blast_Score=91, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320904, Length=447, Percent_Identity=35.5704697986577, Blast_Score=271, Evalue=3e-73,
Organism=Drosophila melanogaster, GI24644341, Length=437, Percent_Identity=40.7322654462243, Blast_Score=299, Evalue=5e-81,
Organism=Drosophila melanogaster, GI24581345, Length=427, Percent_Identity=23.1850117096019, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI221330659, Length=436, Percent_Identity=22.4770642201835, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI19920632, Length=436, Percent_Identity=22.4770642201835, Blast_Score=87, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 65390; Mature: 65259

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS50977 HTH_TETR_2 ; PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRENIIDKADQFIRNKGYNAFSFKDISNDIGIKTASIHYHFPTKSDLGVATIKEHIAR
CCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHH
YEVLKKKVANESPLIKLESFLAVHTQIKHENKVCIVGSLATDLNTLDESIKDELKIFAKL
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHH
VIDWLTEVLTEGKEQNIFDFQTSARTKALMIITNMVAIVQLSRLTNDDDFELVRETILTE
HHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LRPKKIMKRVVVTGLGAVTPIGNNVQEYWNSLINGVSGAAPITRFDTTQFKTKFACEVKN
CCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEECCCHHHCEEEEEEECC
FDASPIFEKNEIRKYDLFTQYALHAADEAVKNANIDFDTLNKNRIGVIWGCGDGGISTFE
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCHHHHH
EQFGEYKLGNGTPRFSPFFIPKRIVNIASGVISIKYGLRGINYTTAAACSASNTAIIDAF
HHHCCEECCCCCCCCCCCHHHHHHHHHHHHHEEEEECCCCCCCHHHHHCCCCCCEEEEHH
NYIRWGKADMIISGGSEASVSESSIGGFNASKALSTLNEDHSKASRPFDVTRDGFVLGEG
HHHCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECC
AGVVILESYEHAVKRNAVILAEIVGGGLAADAYHLTGTHPEGEGAVLGMELALEEAGITP
CCEEEECCHHHHHHCCCEEEEEECCCCCCCCCEEECCCCCCCCCCEEEHHHHHHHCCCCC
DKIDYINAHATSTPAGDLSELKAIEKVFGINPNANISATKSMTGHLLGGAGAIEAVACIK
CHHHEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCEECCCCCCHHCCCCHHHHHHHHHH
ALQENIVPPTINTQTIEQDYAEKFNLTLGKAQAREVNYAMSNTFGFGGHVASSIFKKFKE
HHHHCCCCCCCCCHHHHHHHHHHHCCEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TTRENIIDKADQFIRNKGYNAFSFKDISNDIGIKTASIHYHFPTKSDLGVATIKEHIAR
CCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHH
YEVLKKKVANESPLIKLESFLAVHTQIKHENKVCIVGSLATDLNTLDESIKDELKIFAKL
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHH
VIDWLTEVLTEGKEQNIFDFQTSARTKALMIITNMVAIVQLSRLTNDDDFELVRETILTE
HHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LRPKKIMKRVVVTGLGAVTPIGNNVQEYWNSLINGVSGAAPITRFDTTQFKTKFACEVKN
CCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEECCCHHHCEEEEEEECC
FDASPIFEKNEIRKYDLFTQYALHAADEAVKNANIDFDTLNKNRIGVIWGCGDGGISTFE
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCHHHHH
EQFGEYKLGNGTPRFSPFFIPKRIVNIASGVISIKYGLRGINYTTAAACSASNTAIIDAF
HHHCCEECCCCCCCCCCCHHHHHHHHHHHHHEEEEECCCCCCCHHHHHCCCCCCEEEEHH
NYIRWGKADMIISGGSEASVSESSIGGFNASKALSTLNEDHSKASRPFDVTRDGFVLGEG
HHHCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECC
AGVVILESYEHAVKRNAVILAEIVGGGLAADAYHLTGTHPEGEGAVLGMELALEEAGITP
CCEEEECCHHHHHHCCCEEEEEECCCCCCCCCEEECCCCCCCCCCEEEHHHHHHHCCCCC
DKIDYINAHATSTPAGDLSELKAIEKVFGINPNANISATKSMTGHLLGGAGAIEAVACIK
CHHHEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCEECCCCCCHHCCCCHHHHHHHHHH
ALQENIVPPTINTQTIEQDYAEKFNLTLGKAQAREVNYAMSNTFGFGGHVASSIFKKFKE
HHHHCCCCCCCCCHHHHHHHHHHHCCEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]