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The map label for this gene is dltE [H]

Identifier: 146302015

GI number: 146302015

Start: 5169709

End: 5170434

Strand: Direct

Name: dltE [H]

Synonym: Fjoh_4279

Alternate gene names: 146302015

Gene position: 5169709-5170434 (Clockwise)

Preceding gene: 146302014

Following gene: 146302016

Centisome position: 84.79

GC content: 35.95

Gene sequence:

>726_bases
ATGAATTTATCAAACAACAAAATTTTAATTACGGGAGGTGCAAGCGGTATCGGACTTGGACTTACCGAACGATTTATTCA
GGAAAACAATACCGTGATTATTTGCGGCAGAAGAGAATCAGTTTTAAATGACGTTAAAGCAAAATTCCCTTCAGTAATTA
CAAAAGTATGCGACCTTTCTAAAGAAGAAGACCGCACCGCACTTTATGAATGGATTGCAGCTAATCATCCTGATTTAAAC
GTATTAATCAACAATGCCGGAATTCAAAACTGGATGTCGATTACGGATACTGATTTTTATGCAAACATGAAAAATGAGCT
GACTACCAACATTGAAGCTCCACTGCATTTAACTTCACTATTTATTCAGTTACAATCTCTAAAAACGGTAATGAATGTAA
CTTCTGGATTGGCATTTTCACCATTTGCAAAAGTTCCGGTTTATTCGGCTACAAAAGCGTTTTTTAGATCGTTTACACTT
TCACTTCGTCATTTATTAAAAGAAAAAAACATCGAAGTAATCGAAATTATTCCGCCGGCATTAAACACAGATTTGGGTGG
AATTGGTCTTCACGACGCACATCCAAGCGTAAGCAGTTTTATAGAATCAATTTTTGAACAGTTGAAAGAAGGAAGACAAG
AACTTACTTTTGGAACCAGCGAAACGAGATTAAATGCAAGCGTTCCAGAATTAAAAGCGTCATTTAACGCATTACACGAT
AACTGA

Upstream 100 bases:

>100_bases
CACTTGTGATTTGAATTTCGCAAACATCGGTTTGATATTTACAATTCCCCAAGTCTGCTTCGCTCCTACCTTTGTCTAAT
CAAATTAAAAGATCGAAAAG

Downstream 100 bases:

>100_bases
AATTAATTTTAAACACATAGAAACATAGCTATTGTAAACGCATAAAAGGCATTTCATTTATTAAAACAAACATAGAAATG
CAGCTAAAAAGAAACTTAAT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MNLSNNKILITGGASGIGLGLTERFIQENNTVIICGRRESVLNDVKAKFPSVITKVCDLSKEEDRTALYEWIAANHPDLN
VLINNAGIQNWMSITDTDFYANMKNELTTNIEAPLHLTSLFIQLQSLKTVMNVTSGLAFSPFAKVPVYSATKAFFRSFTL
SLRHLLKEKNIEVIEIIPPALNTDLGGIGLHDAHPSVSSFIESIFEQLKEGRQELTFGTSETRLNASVPELKASFNALHD
N

Sequences:

>Translated_241_residues
MNLSNNKILITGGASGIGLGLTERFIQENNTVIICGRRESVLNDVKAKFPSVITKVCDLSKEEDRTALYEWIAANHPDLN
VLINNAGIQNWMSITDTDFYANMKNELTTNIEAPLHLTSLFIQLQSLKTVMNVTSGLAFSPFAKVPVYSATKAFFRSFTL
SLRHLLKEKNIEVIEIIPPALNTDLGGIGLHDAHPSVSSFIESIFEQLKEGRQELTFGTSETRLNASVPELKASFNALHD
N
>Mature_241_residues
MNLSNNKILITGGASGIGLGLTERFIQENNTVIICGRRESVLNDVKAKFPSVITKVCDLSKEEDRTALYEWIAANHPDLN
VLINNAGIQNWMSITDTDFYANMKNELTTNIEAPLHLTSLFIQLQSLKTVMNVTSGLAFSPFAKVPVYSATKAFFRSFTL
SLRHLLKEKNIEVIEIIPPALNTDLGGIGLHDAHPSVSSFIESIFEQLKEGRQELTFGTSETRLNASVPELKASFNALHD
N

Specific function: Unknown

COG id: COG3967

COG function: function code M; Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI5031737, Length=225, Percent_Identity=26.2222222222222, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI109715829, Length=216, Percent_Identity=27.7777777777778, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=26.5957446808511, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787820, Length=177, Percent_Identity=29.3785310734463, Blast_Score=74, Evalue=1e-14,
Organism=Drosophila melanogaster, GI23397609, Length=163, Percent_Identity=30.0613496932515, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24648693, Length=135, Percent_Identity=31.8518518518519, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21355889, Length=135, Percent_Identity=31.8518518518519, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24584752, Length=220, Percent_Identity=28.1818181818182, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24644339, Length=209, Percent_Identity=28.2296650717703, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26651; Mature: 26651

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSNNKILITGGASGIGLGLTERFIQENNTVIICGRRESVLNDVKAKFPSVITKVCDLS
CCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCC
KEEDRTALYEWIAANHPDLNVLINNAGIQNWMSITDTDFYANMKNELTTNIEAPLHLTSL
CCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHH
FIQLQSLKTVMNVTSGLAFSPFAKVPVYSATKAFFRSFTLSLRHLLKEKNIEVIEIIPPA
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
LNTDLGGIGLHDAHPSVSSFIESIFEQLKEGRQELTFGTSETRLNASVPELKASFNALHD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCC
N
C
>Mature Secondary Structure
MNLSNNKILITGGASGIGLGLTERFIQENNTVIICGRRESVLNDVKAKFPSVITKVCDLS
CCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCC
KEEDRTALYEWIAANHPDLNVLINNAGIQNWMSITDTDFYANMKNELTTNIEAPLHLTSL
CCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHH
FIQLQSLKTVMNVTSGLAFSPFAKVPVYSATKAFFRSFTLSLRHLLKEKNIEVIEIIPPA
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
LNTDLGGIGLHDAHPSVSSFIESIFEQLKEGRQELTFGTSETRLNASVPELKASFNALHD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCC
N
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377; 7797557 [H]