Click here to switch to the map view.

The map label for this gene is xerD [H]

Identifier: 146301384

GI number: 146301384

Start: 4335165

End: 4336082

Strand: Reverse

Name: xerD [H]

Synonym: Fjoh_3642

Alternate gene names: 146301384

Gene position: 4336082-4335165 (Counterclockwise)

Preceding gene: 146301385

Following gene: 146301383

Centisome position: 71.12

GC content: 42.37

Gene sequence:

>918_bases
ATGAAAAAAACGATACAGAGCAGGGAATTTCTAAGGCTCACAGTGGCATTCGGAGAATTTGTAAAAGTCAGGAATTACAA
GCAGGGACGGTCAAACCTCTATAAAAACATCATAACGGAATTTCTGGTCTGGCTGGAACAGGCAGGAATCAGCAGAATCC
AGAATGTGGCCTCAAAAGAATCTGTGAGGTATCTGGATTATCTTTCTTCAAGACCAAAGAAAAGAGGAAACGGCATTCTG
GCTGAAAAGACCATCAAACTGCATCTTTTTGTTCAGGGGCTTTTTCAGGTATATCTGCTGGAAAACAAAGAAATCCAAAA
TGCCTATTATATCCCATCCATCACTGGCGGAACGCAGAAACCCAGAAACATTCTCACAATAGAAGAAATAAAACTTGTTT
ATCATCACGCTGAGAATGAAATGGAAAAAGCTCTGCTTTCCATTGCCTACGGATGCGGACTGAGAAGATCAGAGATTGCC
AGCCTTGATCTGAAAGATGTGAACCTGATAAAAGGAATGCTGGTTGTCAGGCAGGGTAAAGGAAACAAGAGACGTGAAGT
TCCCATGAGCGATACGGTTCTGCAGTACCTGACAAAATATGTCAGGGATGAGAGGCCTGAAAGGCTGACAGGGAGAAACC
AGAATGAGGAAGCCTTTTTCATCAACAGCAGAGGCAGAAGATCGACAGGAGAAAACCTAAATGAGATATTAAACAAAATG
ATTGAGCAGACTGGCAAATTTGAACTTGTCCAGAAAGAAATCACGCTTCACTGCCTGCGCCACAGCATTGCCTTTCATCT
TGCAGAGAATAACGCGGGAATTGACTTTATACGCAGTTTTCTGGGGCATACCCAGATAAATACAACCTACATCTATGCGG
TGCAGAATAAAAAACGCAAACCAGTCGTAAACTTCTAA

Upstream 100 bases:

>100_bases
AAACACTGGCAATACGATGCTGGTGTTCCGCGTTCCGCGGAGTGTGCAAGCGTTCGTTTTCATCACTCAAAAAAACAGCA
TTTAATTAAAGTAAAAGACA

Downstream 100 bases:

>100_bases
AAACGTAACCAATGGAAAACAAGAAACCAGATCTGGAAAATTACCTCAGAGGAATTGTAGCTGAAAAGACAGCGCAGAGC
TATCTCTATACAATCAACCA

Product: phage integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MKKTIQSREFLRLTVAFGEFVKVRNYKQGRSNLYKNIITEFLVWLEQAGISRIQNVASKESVRYLDYLSSRPKKRGNGIL
AEKTIKLHLFVQGLFQVYLLENKEIQNAYYIPSITGGTQKPRNILTIEEIKLVYHHAENEMEKALLSIAYGCGLRRSEIA
SLDLKDVNLIKGMLVVRQGKGNKRREVPMSDTVLQYLTKYVRDERPERLTGRNQNEEAFFINSRGRRSTGENLNEILNKM
IEQTGKFELVQKEITLHCLRHSIAFHLAENNAGIDFIRSFLGHTQINTTYIYAVQNKKRKPVVNF

Sequences:

>Translated_305_residues
MKKTIQSREFLRLTVAFGEFVKVRNYKQGRSNLYKNIITEFLVWLEQAGISRIQNVASKESVRYLDYLSSRPKKRGNGIL
AEKTIKLHLFVQGLFQVYLLENKEIQNAYYIPSITGGTQKPRNILTIEEIKLVYHHAENEMEKALLSIAYGCGLRRSEIA
SLDLKDVNLIKGMLVVRQGKGNKRREVPMSDTVLQYLTKYVRDERPERLTGRNQNEEAFFINSRGRRSTGENLNEILNKM
IEQTGKFELVQKEITLHCLRHSIAFHLAENNAGIDFIRSFLGHTQINTTYIYAVQNKKRKPVVNF
>Mature_305_residues
MKKTIQSREFLRLTVAFGEFVKVRNYKQGRSNLYKNIITEFLVWLEQAGISRIQNVASKESVRYLDYLSSRPKKRGNGIL
AEKTIKLHLFVQGLFQVYLLENKEIQNAYYIPSITGGTQKPRNILTIEEIKLVYHHAENEMEKALLSIAYGCGLRRSEIA
SLDLKDVNLIKGMLVVRQGKGNKRREVPMSDTVLQYLTKYVRDERPERLTGRNQNEEAFFINSRGRRSTGENLNEILNKM
IEQTGKFELVQKEITLHCLRHSIAFHLAENNAGIDFIRSFLGHTQINTTYIYAVQNKKRKPVVNF

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=274, Percent_Identity=25.1824817518248, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1790244, Length=153, Percent_Identity=30.718954248366, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 35371; Mature: 35371

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTIQSREFLRLTVAFGEFVKVRNYKQGRSNLYKNIITEFLVWLEQAGISRIQNVASKE
CCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVRYLDYLSSRPKKRGNGILAEKTIKLHLFVQGLFQVYLLENKEIQNAYYIPSITGGTQK
HHHHHHHHHCCCCCCCCCCEEHHHEEHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCC
PRNILTIEEIKLVYHHAENEMEKALLSIAYGCGLRRSEIASLDLKDVNLIKGMLVVRQGK
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHEEECCC
GNKRREVPMSDTVLQYLTKYVRDERPERLTGRNQNEEAFFINSRGRRSTGENLNEILNKM
CCCCCCCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHH
IEQTGKFELVQKEITLHCLRHSIAFHLAENNAGIDFIRSFLGHTQINTTYIYAVQNKKRK
HHHCCCHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHCCCCCCEEEEEEEECCCCC
PVVNF
CCCCC
>Mature Secondary Structure
MKKTIQSREFLRLTVAFGEFVKVRNYKQGRSNLYKNIITEFLVWLEQAGISRIQNVASKE
CCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVRYLDYLSSRPKKRGNGILAEKTIKLHLFVQGLFQVYLLENKEIQNAYYIPSITGGTQK
HHHHHHHHHCCCCCCCCCCEEHHHEEHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCC
PRNILTIEEIKLVYHHAENEMEKALLSIAYGCGLRRSEIASLDLKDVNLIKGMLVVRQGK
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHEEECCC
GNKRREVPMSDTVLQYLTKYVRDERPERLTGRNQNEEAFFINSRGRRSTGENLNEILNKM
CCCCCCCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHH
IEQTGKFELVQKEITLHCLRHSIAFHLAENNAGIDFIRSFLGHTQINTTYIYAVQNKKRK
HHHCCCHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHCCCCCCEEEEEEEECCCCC
PVVNF
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]