Click here to switch to the map view.

The map label for this gene is corA [H]

Identifier: 146301272

GI number: 146301272

Start: 4210950

End: 4212023

Strand: Reverse

Name: corA [H]

Synonym: Fjoh_3530

Alternate gene names: 146301272

Gene position: 4212023-4210950 (Counterclockwise)

Preceding gene: 146301273

Following gene: 146301271

Centisome position: 69.08

GC content: 31.47

Gene sequence:

>1074_bases
ATGAGAAAGATCAAATACAAAAAGGGACGCAAGCTGCAGCATATTACATTAGAGTATACAGGTTCGCATAAAGAGCATGA
AACCGAAATGCAGCTTTTCGTATATGATGATGCAGATGTTGTTGAGTATGATAAGTTTACGGTTTTAGCTTTGAATTCTT
GTTTTGACTACACTAAAAATAATTGGTTAAATGTTCATGGTTTAAATGATATTAACTTACTTAAAACAATTGGCACGCAT
TTTAAGTTTGATGATTTTCTTTTAGCCGATATTTTAAACACAACCAAAAGAACCAAGTTAGAAGAACAGCAAAACGTTTT
ATTTTTTAATATAAAATCGCTCCTGCCTTCTGAATATTCAGATAATATAAGCGTTGAACAGATTAGTTTTATTCTGAAAG
AAGGAATACTAATTTCGTTTCAGGAAAAACGAAGCGATTTCTTTACCCATATACGCGAACGACTTCGTACACATGCAGGA
ATTGTAAGGACAAAAAAAGTAGATTATCTCTTGTATTTACTTTTAGATGCCGTTATGGAAAACTTCTATATTACACTCGA
AGATGAAGAAGATAAAATAGAAGAATTAATCAATTTGACTAAAAAAGATGCAAAGCCTGTTATTTTAGAAAAAATTGAAA
ATCACCGTGATAATTTAAACTTCTTAAAGCGTTCTATAATTCCACTTAGAGATTCATTGTATTATCTCAAAACGATTAAA
GACGATGATGAAAACAACGGCTTAATTCAAAGAGAGACATTTAATTTCTTTGTCAGGCTGCATCAAAAGAGTTTAGAACT
TTTAGAACAGATAGAATCGGATATGAGCGCATTGGAAAGTGCTTCTAATTTTTATTTTTCGGAACAAAGCCGAAAAATGA
ATGAAATTATGAAAACACTGACTATAATTTCAGCCATATTTATTCCGCTGACCTTTATTGTTGGAGTGTACGGAATGAAC
TTTGAAAACATGCCCGAACTTAAAACCCAAAACGGCTATTTTGTGGTTATGGGAATCATGTTTTTATTGGTAATAGCCCT
AATCGTTTATTTCAAAAAACGACGTTGGTTTTAA

Upstream 100 bases:

>100_bases
TTAAGTCATTCTATCTTTTTAAATCTTTCTGAGCAAACTGACAATTGTCATTTCTCATTCAGATTCTTTTTCGTAATATT
ACTATTGTAAATTTTTTTGA

Downstream 100 bases:

>100_bases
CGTTTGTTGCAACTGTTGAACGATTTGATTTGTGTAAATTTGTTATTTAGAATAAATATAAATAATTATGAGTAAAGCAA
TATATATAGCCACTAGTGAT

Product: magnesium and cobalt transport protein CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MRKIKYKKGRKLQHITLEYTGSHKEHETEMQLFVYDDADVVEYDKFTVLALNSCFDYTKNNWLNVHGLNDINLLKTIGTH
FKFDDFLLADILNTTKRTKLEEQQNVLFFNIKSLLPSEYSDNISVEQISFILKEGILISFQEKRSDFFTHIRERLRTHAG
IVRTKKVDYLLYLLLDAVMENFYITLEDEEDKIEELINLTKKDAKPVILEKIENHRDNLNFLKRSIIPLRDSLYYLKTIK
DDDENNGLIQRETFNFFVRLHQKSLELLEQIESDMSALESASNFYFSEQSRKMNEIMKTLTIISAIFIPLTFIVGVYGMN
FENMPELKTQNGYFVVMGIMFLLVIALIVYFKKRRWF

Sequences:

>Translated_357_residues
MRKIKYKKGRKLQHITLEYTGSHKEHETEMQLFVYDDADVVEYDKFTVLALNSCFDYTKNNWLNVHGLNDINLLKTIGTH
FKFDDFLLADILNTTKRTKLEEQQNVLFFNIKSLLPSEYSDNISVEQISFILKEGILISFQEKRSDFFTHIRERLRTHAG
IVRTKKVDYLLYLLLDAVMENFYITLEDEEDKIEELINLTKKDAKPVILEKIENHRDNLNFLKRSIIPLRDSLYYLKTIK
DDDENNGLIQRETFNFFVRLHQKSLELLEQIESDMSALESASNFYFSEQSRKMNEIMKTLTIISAIFIPLTFIVGVYGMN
FENMPELKTQNGYFVVMGIMFLLVIALIVYFKKRRWF
>Mature_357_residues
MRKIKYKKGRKLQHITLEYTGSHKEHETEMQLFVYDDADVVEYDKFTVLALNSCFDYTKNNWLNVHGLNDINLLKTIGTH
FKFDDFLLADILNTTKRTKLEEQQNVLFFNIKSLLPSEYSDNISVEQISFILKEGILISFQEKRSDFFTHIRERLRTHAG
IVRTKKVDYLLYLLLDAVMENFYITLEDEEDKIEELINLTKKDAKPVILEKIENHRDNLNFLKRSIIPLRDSLYYLKTIK
DDDENNGLIQRETFNFFVRLHQKSLELLEQIESDMSALESASNFYFSEQSRKMNEIMKTLTIISAIFIPLTFIVGVYGMN
FENMPELKTQNGYFVVMGIMFLLVIALIVYFKKRRWF

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=254, Percent_Identity=26.3779527559055, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 42326; Mature: 42326

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIKYKKGRKLQHITLEYTGSHKEHETEMQLFVYDDADVVEYDKFTVLALNSCFDYTKN
CCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEECCCCEEEECCEEEEEEHHHHHHCCC
NWLNVHGLNDINLLKTIGTHFKFDDFLLADILNTTKRTKLEEQQNVLFFNIKSLLPSEYS
CEEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCCC
DNISVEQISFILKEGILISFQEKRSDFFTHIRERLRTHAGIVRTKKVDYLLYLLLDAVME
CCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NFYITLEDEEDKIEELINLTKKDAKPVILEKIENHRDNLNFLKRSIIPLRDSLYYLKTIK
CEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCHHHCEEEEEEEC
DDDENNGLIQRETFNFFVRLHQKSLELLEQIESDMSALESASNFYFSEQSRKMNEIMKTL
CCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
TIISAIFIPLTFIVGVYGMNFENMPELKTQNGYFVVMGIMFLLVIALIVYFKKRRWF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRKIKYKKGRKLQHITLEYTGSHKEHETEMQLFVYDDADVVEYDKFTVLALNSCFDYTKN
CCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEECCCCEEEECCEEEEEEHHHHHHCCC
NWLNVHGLNDINLLKTIGTHFKFDDFLLADILNTTKRTKLEEQQNVLFFNIKSLLPSEYS
CEEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCCC
DNISVEQISFILKEGILISFQEKRSDFFTHIRERLRTHAGIVRTKKVDYLLYLLLDAVME
CCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NFYITLEDEEDKIEELINLTKKDAKPVILEKIENHRDNLNFLKRSIIPLRDSLYYLKTIK
CEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCHHHCEEEEEEEC
DDDENNGLIQRETFNFFVRLHQKSLELLEQIESDMSALESASNFYFSEQSRKMNEIMKTL
CCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
TIISAIFIPLTFIVGVYGMNFENMPELKTQNGYFVVMGIMFLLVIALIVYFKKRRWF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]