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The map label for this gene is add [C]

Identifier: 146301235

GI number: 146301235

Start: 4169697

End: 4171112

Strand: Direct

Name: add [C]

Synonym: Fjoh_3493

Alternate gene names: 146301235

Gene position: 4169697-4171112 (Clockwise)

Preceding gene: 146301234

Following gene: 146301236

Centisome position: 68.39

GC content: 32.98

Gene sequence:

>1416_bases
ATGACAAGGATAATTACGCTTTTCTGTATTTTTATAGCACAAATCGGCTTTTCTCAATCAGCTGAGAGTTATTTAGAAAA
AATCAGAAATAATGAAGCTCTCTTAACAGCTTTTTTTCAACAAATGCCAAAAGGAGGCGATTTACACCACCATTTTTCAG
GATCCGTTTATGCAGAACCTCTTTTAGAAAGAGCGATTGCAGAAGACTTTTATTTGAATTTAGAAACTATGGCAGTTTCT
AAAACCAAACCTGCAAACGGAAACTGGGAAAATTTCTCATCTCTTAAAAACAAAGGAAAATTAGACTATTACGAACAGCA
GATTATGCAGACTTGGTCGGTAAAAGACTATAATGGTTCTGTACCTTCTGACGATCAGTTTTTTGATTCTTTTATGAAAT
TCGAGCCGACTATTCAAGGTCATTTTGCAGAAGGAATGCTCGAATTAAAAAAACGTGCCATTGCCGAAAATGTAAGTTAT
ATCGAAACACAATTATCGACAATTCCATGCGATATGAATGTTTCAGATTTAGCTGATTTCAACACAAAACTTCGCCAATC
TGCTGATCAAAAAGACGAAAAAGCAGTTCTAAAACTTTTAGATGATTTGTATAAATCGCTTCAGAAAAAAGACGCTAAAA
AATATGCTGAAGATTTCAATACTAATTTCATAACAAAACTGCACAAGGATTTAAAAATGGATGACGATAAATTCACCATG
CGTTATCAAAACTTTGTACTTCGTTTTATGGAACCTGTAGATTTATTCAAAAACCTGGTTATCGCTTTTATTTCATCAAA
CGAAAATAAACTGACTGCCGGTGTAAACATCGTTTCTCCAGAACACGGACAGACTTCTATGAAAGATTACTGGCTTCACA
TGGTAATGTTTAAATACTGTCATTCTAAATTTCCAGACGTAAAATATACGCTTCATGCGGGTGAATTAACTTTAGGATTG
GTTCAGCCAGAAGAATTAACGTGGCACATTAACGATGCGATTTATGTTGCCGGTGCAAACAGAATTGGTCACGGAGTTGA
TATCGCTTACGAAGCCAATTCGTATGATTTATTAAAATATATGGCTCAAAAAAATATTCCAATTGAAATCAATTTAGTGA
GCAACGAATTCATTTTGAAGGTAAAAGAAAACAGACATCCGTTTACGCTTTACAAAGAATTTAATGTGCCAATTGTGATC
AGTACAGACGATGCAGGAATTTTAAGAAGCAATATGACAGAACAATATGTTTTACTGGCAAAAAGATATCCTGACGTAAA
TTATGAAACGATTAAAAAATACGTTTACAACAGCATCAATTACAGTTTTATTCAGGATGCATCGGTAAAAAAACAATTAA
TTAAAGATTTAGATAATCGTTTTAAAACTTTTGAATCGAAATTTTCTAAAAACTAA

Upstream 100 bases:

>100_bases
AAAACTTTGCGAACTTTGCGGTAAAACCCACAACAACAAAAAACAAATTTTCAAAATTCTCCGAAAACTCGTATATTTGC
ATGTAATTTAAACTTAGAGT

Downstream 100 bases:

>100_bases
TATTTAATTTCACGCAGATTTTACAGATTTAAGCTGATTTGTCCAGATTTTTATCTAAAAAATTAAATCTGCTCAAATCT
GTAAAATCTGCGTGCAAAAA

Product: adenosine/AMP deaminase

Products: Inosine; ammonia [C]

Alternate protein names: Adenosine/AMP Deaminase; Adenosine/AMP Deaminase Family Protein

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MTRIITLFCIFIAQIGFSQSAESYLEKIRNNEALLTAFFQQMPKGGDLHHHFSGSVYAEPLLERAIAEDFYLNLETMAVS
KTKPANGNWENFSSLKNKGKLDYYEQQIMQTWSVKDYNGSVPSDDQFFDSFMKFEPTIQGHFAEGMLELKKRAIAENVSY
IETQLSTIPCDMNVSDLADFNTKLRQSADQKDEKAVLKLLDDLYKSLQKKDAKKYAEDFNTNFITKLHKDLKMDDDKFTM
RYQNFVLRFMEPVDLFKNLVIAFISSNENKLTAGVNIVSPEHGQTSMKDYWLHMVMFKYCHSKFPDVKYTLHAGELTLGL
VQPEELTWHINDAIYVAGANRIGHGVDIAYEANSYDLLKYMAQKNIPIEINLVSNEFILKVKENRHPFTLYKEFNVPIVI
STDDAGILRSNMTEQYVLLAKRYPDVNYETIKKYVYNSINYSFIQDASVKKQLIKDLDNRFKTFESKFSKN

Sequences:

>Translated_471_residues
MTRIITLFCIFIAQIGFSQSAESYLEKIRNNEALLTAFFQQMPKGGDLHHHFSGSVYAEPLLERAIAEDFYLNLETMAVS
KTKPANGNWENFSSLKNKGKLDYYEQQIMQTWSVKDYNGSVPSDDQFFDSFMKFEPTIQGHFAEGMLELKKRAIAENVSY
IETQLSTIPCDMNVSDLADFNTKLRQSADQKDEKAVLKLLDDLYKSLQKKDAKKYAEDFNTNFITKLHKDLKMDDDKFTM
RYQNFVLRFMEPVDLFKNLVIAFISSNENKLTAGVNIVSPEHGQTSMKDYWLHMVMFKYCHSKFPDVKYTLHAGELTLGL
VQPEELTWHINDAIYVAGANRIGHGVDIAYEANSYDLLKYMAQKNIPIEINLVSNEFILKVKENRHPFTLYKEFNVPIVI
STDDAGILRSNMTEQYVLLAKRYPDVNYETIKKYVYNSINYSFIQDASVKKQLIKDLDNRFKTFESKFSKN
>Mature_470_residues
TRIITLFCIFIAQIGFSQSAESYLEKIRNNEALLTAFFQQMPKGGDLHHHFSGSVYAEPLLERAIAEDFYLNLETMAVSK
TKPANGNWENFSSLKNKGKLDYYEQQIMQTWSVKDYNGSVPSDDQFFDSFMKFEPTIQGHFAEGMLELKKRAIAENVSYI
ETQLSTIPCDMNVSDLADFNTKLRQSADQKDEKAVLKLLDDLYKSLQKKDAKKYAEDFNTNFITKLHKDLKMDDDKFTMR
YQNFVLRFMEPVDLFKNLVIAFISSNENKLTAGVNIVSPEHGQTSMKDYWLHMVMFKYCHSKFPDVKYTLHAGELTLGLV
QPEELTWHINDAIYVAGANRIGHGVDIAYEANSYDLLKYMAQKNIPIEINLVSNEFILKVKENRHPFTLYKEFNVPIVIS
TDDAGILRSNMTEQYVLLAKRYPDVNYETIKKYVYNSINYSFIQDASVKKQLIKDLDNRFKTFESKFSKN

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.5.4.4 [C]

Molecular weight: Translated: 54570; Mature: 54439

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCCHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TRIITLFCIFIAQIGFSQSAESYLEKIRNNEALLTAFFQQMPKGGDLHHHFSGSVYAEP
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
LLERAIAEDFYLNLETMAVSKTKPANGNWENFSSLKNKGKLDYYEQQIMQTWSVKDYNGS
HHHHHHHHHHHEEEEHEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCC
VPSDDQFFDSFMKFEPTIQGHFAEGMLELKKRAIAENVSYIETQLSTIPCDMNVSDLADF
CCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
NTKLRQSADQKDEKAVLKLLDDLYKSLQKKDAKKYAEDFNTNFITKLHKDLKMDDDKFTM
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHH
RYQNFVLRFMEPVDLFKNLVIAFISSNENKLTAGVNIVSPEHGQTSMKDYWLHMVMFKYC
HHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEECEEEECCCCCCCHHHHHHHHHHHHHHH
HSKFPDVKYTLHAGELTLGLVQPEELTWHINDAIYVAGANRIGHGVDIAYEANSYDLLKY
HCCCCCCEEEEEECCEEEEEECCCCEEEEECCEEEEECCCCCCCCEEEEEECCCHHHHHH
MAQKNIPIEINLVSNEFILKVKENRHPFTLYKEFNVPIVISTDDAGILRSNMTEQYVLLA
HHHCCCCEEEEEECCEEEEEEECCCCCEEEEEECCCEEEEECCCCHHHHHCCCHHHHHHH
KRYPDVNYETIKKYVYNSINYSFIQDASVKKQLIKDLDNRFKTFESKFSKN
HHCCCCCHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.06 {adenosine}} [C]

Substrates: Adenosine; H+; H2O [C]

Specific reaction: Adenosine + H+ + H2O --> Inosine + ammonia [C]

General reaction: Amidine hydrolysis [C]

Inhibitor: 1, 6-Dihydro-6-(hydroxy methyl) purineriboside; 2, 6-Diaminopurine sulfate; 4-Amino-5-imidazolecarboxamide HCl; 4-Amino-5-imidazolecarboxamide ribonucleoside; 6-Chloropurine; Adenine; Deoxyc of ormycin; Erythro-9-(-2-hydroxy -3-nonyl) adenine; Iodopurine;

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA