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The map label for this gene is barA [H]

Identifier: 146301095

GI number: 146301095

Start: 4010603

End: 4010968

Strand: Reverse

Name: barA [H]

Synonym: Fjoh_3353

Alternate gene names: 146301095

Gene position: 4010968-4010603 (Counterclockwise)

Preceding gene: 146301096

Following gene: 146301094

Centisome position: 65.79

GC content: 38.25

Gene sequence:

>366_bases
ATGAGTAAAAAACGACTTTTAATTGTAGATGACGATTCCAGAAATATATTCGCATTAACGCATACTTTGCGCGTCAAATC
ATACGATTGTTTGTCTTGCACAAGTGCCGAAGAAGCTTTAAAACTGCTGAAATCTGATGAAGAGATCGACGCTGTTTTAC
TGGATATGATGATGCCCGAAATGGACGGTTACGATGCAATTCCGTTAATAAAAGCAATTCCGTCCAGAAAATCGGTATTT
GTTATTGCAGTTACTGCCCAGGCTATGACAGGCGATAAAGAAAAGTGTTTAGAGGCTGGAGCCGATGATTACATCTCTAA
ACCAGTTGATGTTGATAAGTTACTGCTTATACTAAGCAAAATTTGA

Upstream 100 bases:

>100_bases
GGATTCTGAAATTCGGCTATAGTAAAGAAAAGATAAATGCTGCAGATTTTAATAGATTAAAAATCCCTTTAATCTGCGGC
ACAAAAAATATAAAACAAAT

Downstream 100 bases:

>100_bases
TGAATTATGATTGAGGATATTGAGCTTGAAACACTTATCAATGAGGTTTATGAATATTATGGTTTTGATTTTAGCAGTTA
TTCGAGAGCATCGCTAAAAA

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 121; Mature: 120

Protein sequence:

>121_residues
MSKKRLLIVDDDSRNIFALTHTLRVKSYDCLSCTSAEEALKLLKSDEEIDAVLLDMMMPEMDGYDAIPLIKAIPSRKSVF
VIAVTAQAMTGDKEKCLEAGADDYISKPVDVDKLLLILSKI

Sequences:

>Translated_121_residues
MSKKRLLIVDDDSRNIFALTHTLRVKSYDCLSCTSAEEALKLLKSDEEIDAVLLDMMMPEMDGYDAIPLIKAIPSRKSVF
VIAVTAQAMTGDKEKCLEAGADDYISKPVDVDKLLLILSKI
>Mature_120_residues
SKKRLLIVDDDSRNIFALTHTLRVKSYDCLSCTSAEEALKLLKSDEEIDAVLLDMMMPEMDGYDAIPLIKAIPSRKSVFV
IAVTAQAMTGDKEKCLEAGADDYISKPVDVDKLLLILSKI

Specific function: Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. Phosphorylates UvrY, probably via a four-step phosphorelay [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=109, Percent_Identity=37.6146788990826, Blast_Score=72, Evalue=1e-14,
Organism=Escherichia coli, GI145693157, Length=107, Percent_Identity=39.2523364485981, Blast_Score=67, Evalue=2e-13,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=34.4827586206897, Blast_Score=61, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR019247
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF09984 DUF2222; PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 13409; Mature: 13278

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKRLLIVDDDSRNIFALTHTLRVKSYDCLSCTSAEEALKLLKSDEEIDAVLLDMMMPE
CCCCCEEEEECCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCC
MDGYDAIPLIKAIPSRKSVFVIAVTAQAMTGDKEKCLEAGADDYISKPVDVDKLLLILSK
CCCCCCCHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHCCCCHHHCCCCCHHHHHHHHHC
I
C
>Mature Secondary Structure 
SKKRLLIVDDDSRNIFALTHTLRVKSYDCLSCTSAEEALKLLKSDEEIDAVLLDMMMPE
CCCCEEEEECCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCC
MDGYDAIPLIKAIPSRKSVFVIAVTAQAMTGDKEKCLEAGADDYISKPVDVDKLLLILSK
CCCCCCCHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHCCCCHHHCCCCCHHHHHHHHHC
I
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]