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The map label for this gene is 146301047

Identifier: 146301047

GI number: 146301047

Start: 3945432

End: 3947999

Strand: Direct

Name: 146301047

Synonym: Fjoh_3303

Alternate gene names: NA

Gene position: 3945432-3947999 (Clockwise)

Preceding gene: 146301046

Following gene: 146301054

Centisome position: 64.71

GC content: 34.81

Gene sequence:

>2568_bases
ATGCCTATGTCACTGTCTAAATACAACGAAAAGAGAGATTTTAAGCAAACACGCGAGCCAAAAGGCAAGGTTGAAAAATC
GGCCAATGAATTGATTTTTGTCGTTCAAAAACATGCTGCATCGCATTTGCATTATGATTTTAGACTGGAAATGAACGGCG
TTCTCAAAAGCTGGGCAGTTCCAAAAGGTCCTTCAATGGATCCCGAAGTAAAACGTCTTGCTATGATGGTCGAAGATCAT
CCTTACAGTTATAAAGATTTTGAAGGAACAATTCCGGCCGGAAACTATGGCGCCGGAAATGTAATTGTATGGGATAACGG
TACGTATACTTCTGACGAAAAAACAGCTTCTGATGAAAAACAGCTTTTAGCCGATCTTAAAAAAGGCCGTCTGAGTTTTG
TCTTAAAAGGAAAAAAACTTAAAGGCGAATTTTCATTGGTAAAACTTCATGGAAAACAGGAAAATGCCTGGCTTTTAATC
AAAAAACAGGATAAATATGCTTCAGAATCAGATATATTAGAAAAAGACAAATCGGTTATTTCTAAAAGAAGTCTGGAAGA
ACTGGAGAAAAAATCAGATAAGATGACCGCCAAATCTGAAGAAAAAGAAACCAAACTAAAAGCCATAAAAAAAAAGCCTA
AAGCAAAAACTATAAAAGCCGAATTCATCAAACCGATGCTTGCCAATACTACAGAAAAACCTTTTGATGACGAGGAATGG
ATTTTTGAAAATAAATACGACGGTTACCGTACGATTGCTGTTGTTAACTCTGATAAAACAGCATTATTCAGCAGAAATAA
AATTTCTTTTGATATCAATTTTAAACCCATTGCAGACGAATTAAAAAAAATAGATCATACCGTAGTTCTCGATGGCGAAA
TTGTAGTGGAAAATAAATCTGGACGAGCCGATTTTCAACTGCTTCAAAACTATTTAAAAACCGGAATTGGAAATTTAAAA
TATTATGTTTTTGATTTACTCAATTTAGACGGAAATGAGGTGACAGAATTGTCTCTCCTCGATCGAAAAGAACTTCTTAA
AATTTTATTTAATAAATATTCTTTTTCGAATATTTTCTATTCTGAACATACAATTGCAAATGGAATTGAGCAATTTGAAA
AAGCGCGAAAAAATAACAGCGAAGGAATAATTGCCAAAAAAGCAGACAGTTCTTATACCGCTGGCGGAAGAAGCAATAAC
TGGCTGAAAATAAAGATTTCTAACGAAGAAGAAGCCATTATTATCGGGATTACAGAACCCAAAAATTCCCGAAAATATTT
TGGCGCAATTTTGCTGGGTCAATACAACGGTAAAAATCTGCAATATATAGGGAAATGCGGCACTGGATTTACCGAAGCTG
TTTTAAAAGAACTTTATACTAAATTAAAACCTCTTTTTACAGATCAATCACCATTGCAGGAAAAAGTTCCTTTACGGGAT
ACTATTCAATGGGTAAAGCCCAAATTAGTCTGTCAGGTAAAATACTCTGAATGGACGCAGGATAACAATTTAAGACATCC
GGTTTATCTGGGATTACGAATTGACAAAAAAGCCCAAGAGGTTGTTTTTAATGGAAATGACAACACTAAAACTATAAATC
ACAATCAGGAAAAAATGGAAAATTTAAAAGAACATACAACTGAAAATGATTACGATTTAAAAATTGGAAAAACGATACTC
CATTTAACCAATCAAAATAAAATTTATTTCCCGCAGGACGGAATTACAAAAGGCGATATTATTCAATATTATAATGAAGC
CGCACCGTTAATGCTGCCCTATTTAAAAGACCGTCCAGAATCGATGAACCGTTTTCCTAACGGAATTGATTCGCCTGGTT
TTTACCAAAAAGATATTGATGCCGACAAAACTCCAAAATGGCTGAAAACCAAAAAAATCTTTTCAGAATCAAACGATGCC
GATGTTAATTATCTTATTTGTAATGATAAAGAAACGCTGCTTTATATGGCAAATTTGGGCTGTATTGAAATCAATCCGTG
GAATTCCACTATAAAAAACATTTCGAATCCGGATTGGCTGGTAATCGATTTAGATCCTGCGAAAGAAGATGATTTTAAAT
CTGTAATCGAAACAGCATTAGTAGTTAAAGAAGTTATGGATGAATTGCAAACCGAGTGTTTGTGCAAAACTTCCGGAGCT
TCAGGACTGCATATTTATATACCGCTTGGCGCACAATACGACTATGATTCTATTAAAATCCTGGCCGAATTAATTGCAAA
AGAAGTACATACAAGACTGCCTAAAACTACTTCAATTGAACGAAGCATCAAGAAAAGAAAAAATAAATTGTATATCGATT
TTCTTCAAAACCGAAGAGGACAAACTTTGGCCGCGCCCTACTCTGTCCGCCCGCAACCAGGCGCAACAGTTTCGACTCCG
TTAGAATGGAATGAAGTAAATGAAAAACTTCATCCGTCGCAGTTTACGATAAAAAATGTATTGCAGCGTTTTGAGAAAAA
GGGTGATTTATGGAAACCTGTTTTGTCAAAAGGTGCCAATATCAAAAAGATTATCAAGAAATTAGAGGAAAAACAACTGG
AAAATTAA

Upstream 100 bases:

>100_bases
TTTAAAGGTTATTATATTCAGCTGTTCTTTGCTCATATAATTTTTGCTATTGTCGCAACAGTTCTCTACTCTATTACAAT
GACAATTTTAATATTAACAA

Downstream 100 bases:

>100_bases
AATCTAAGACTAAGAAGATTTTTTCTTCTTAGTCTCTAAACTGGCTTTTAACATTGACATTAAATCGTCGCCTTGTTTAT
GAACCACTTTCATTTTAGGA

Product: ATP dependent DNA ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 855; Mature: 854

Protein sequence:

>855_residues
MPMSLSKYNEKRDFKQTREPKGKVEKSANELIFVVQKHAASHLHYDFRLEMNGVLKSWAVPKGPSMDPEVKRLAMMVEDH
PYSYKDFEGTIPAGNYGAGNVIVWDNGTYTSDEKTASDEKQLLADLKKGRLSFVLKGKKLKGEFSLVKLHGKQENAWLLI
KKQDKYASESDILEKDKSVISKRSLEELEKKSDKMTAKSEEKETKLKAIKKKPKAKTIKAEFIKPMLANTTEKPFDDEEW
IFENKYDGYRTIAVVNSDKTALFSRNKISFDINFKPIADELKKIDHTVVLDGEIVVENKSGRADFQLLQNYLKTGIGNLK
YYVFDLLNLDGNEVTELSLLDRKELLKILFNKYSFSNIFYSEHTIANGIEQFEKARKNNSEGIIAKKADSSYTAGGRSNN
WLKIKISNEEEAIIIGITEPKNSRKYFGAILLGQYNGKNLQYIGKCGTGFTEAVLKELYTKLKPLFTDQSPLQEKVPLRD
TIQWVKPKLVCQVKYSEWTQDNNLRHPVYLGLRIDKKAQEVVFNGNDNTKTINHNQEKMENLKEHTTENDYDLKIGKTIL
HLTNQNKIYFPQDGITKGDIIQYYNEAAPLMLPYLKDRPESMNRFPNGIDSPGFYQKDIDADKTPKWLKTKKIFSESNDA
DVNYLICNDKETLLYMANLGCIEINPWNSTIKNISNPDWLVIDLDPAKEDDFKSVIETALVVKEVMDELQTECLCKTSGA
SGLHIYIPLGAQYDYDSIKILAELIAKEVHTRLPKTTSIERSIKKRKNKLYIDFLQNRRGQTLAAPYSVRPQPGATVSTP
LEWNEVNEKLHPSQFTIKNVLQRFEKKGDLWKPVLSKGANIKKIIKKLEEKQLEN

Sequences:

>Translated_855_residues
MPMSLSKYNEKRDFKQTREPKGKVEKSANELIFVVQKHAASHLHYDFRLEMNGVLKSWAVPKGPSMDPEVKRLAMMVEDH
PYSYKDFEGTIPAGNYGAGNVIVWDNGTYTSDEKTASDEKQLLADLKKGRLSFVLKGKKLKGEFSLVKLHGKQENAWLLI
KKQDKYASESDILEKDKSVISKRSLEELEKKSDKMTAKSEEKETKLKAIKKKPKAKTIKAEFIKPMLANTTEKPFDDEEW
IFENKYDGYRTIAVVNSDKTALFSRNKISFDINFKPIADELKKIDHTVVLDGEIVVENKSGRADFQLLQNYLKTGIGNLK
YYVFDLLNLDGNEVTELSLLDRKELLKILFNKYSFSNIFYSEHTIANGIEQFEKARKNNSEGIIAKKADSSYTAGGRSNN
WLKIKISNEEEAIIIGITEPKNSRKYFGAILLGQYNGKNLQYIGKCGTGFTEAVLKELYTKLKPLFTDQSPLQEKVPLRD
TIQWVKPKLVCQVKYSEWTQDNNLRHPVYLGLRIDKKAQEVVFNGNDNTKTINHNQEKMENLKEHTTENDYDLKIGKTIL
HLTNQNKIYFPQDGITKGDIIQYYNEAAPLMLPYLKDRPESMNRFPNGIDSPGFYQKDIDADKTPKWLKTKKIFSESNDA
DVNYLICNDKETLLYMANLGCIEINPWNSTIKNISNPDWLVIDLDPAKEDDFKSVIETALVVKEVMDELQTECLCKTSGA
SGLHIYIPLGAQYDYDSIKILAELIAKEVHTRLPKTTSIERSIKKRKNKLYIDFLQNRRGQTLAAPYSVRPQPGATVSTP
LEWNEVNEKLHPSQFTIKNVLQRFEKKGDLWKPVLSKGANIKKIIKKLEEKQLEN
>Mature_854_residues
PMSLSKYNEKRDFKQTREPKGKVEKSANELIFVVQKHAASHLHYDFRLEMNGVLKSWAVPKGPSMDPEVKRLAMMVEDHP
YSYKDFEGTIPAGNYGAGNVIVWDNGTYTSDEKTASDEKQLLADLKKGRLSFVLKGKKLKGEFSLVKLHGKQENAWLLIK
KQDKYASESDILEKDKSVISKRSLEELEKKSDKMTAKSEEKETKLKAIKKKPKAKTIKAEFIKPMLANTTEKPFDDEEWI
FENKYDGYRTIAVVNSDKTALFSRNKISFDINFKPIADELKKIDHTVVLDGEIVVENKSGRADFQLLQNYLKTGIGNLKY
YVFDLLNLDGNEVTELSLLDRKELLKILFNKYSFSNIFYSEHTIANGIEQFEKARKNNSEGIIAKKADSSYTAGGRSNNW
LKIKISNEEEAIIIGITEPKNSRKYFGAILLGQYNGKNLQYIGKCGTGFTEAVLKELYTKLKPLFTDQSPLQEKVPLRDT
IQWVKPKLVCQVKYSEWTQDNNLRHPVYLGLRIDKKAQEVVFNGNDNTKTINHNQEKMENLKEHTTENDYDLKIGKTILH
LTNQNKIYFPQDGITKGDIIQYYNEAAPLMLPYLKDRPESMNRFPNGIDSPGFYQKDIDADKTPKWLKTKKIFSESNDAD
VNYLICNDKETLLYMANLGCIEINPWNSTIKNISNPDWLVIDLDPAKEDDFKSVIETALVVKEVMDELQTECLCKTSGAS
GLHIYIPLGAQYDYDSIKILAELIAKEVHTRLPKTTSIERSIKKRKNKLYIDFLQNRRGQTLAAPYSVRPQPGATVSTPL
EWNEVNEKLHPSQFTIKNVLQRFEKKGDLWKPVLSKGANIKKIIKKLEEKQLEN

Specific function: Unknown

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

Organism=Homo sapiens, GI4557719, Length=380, Percent_Identity=25, Blast_Score=91, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71985269, Length=375, Percent_Identity=26.1333333333333, Blast_Score=85, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320038, Length=369, Percent_Identity=25.2032520325203, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24762424, Length=380, Percent_Identity=25, Blast_Score=74, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR002755
- InterPro:   IPR014144
- InterPro:   IPR014145
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF01896 DNA_primase_S [H]

EC number: NA

Molecular weight: Translated: 98006; Mature: 97875

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMSLSKYNEKRDFKQTREPKGKVEKSANELIFVVQKHAASHLHYDFRLEMNGVLKSWAV
CCCCCHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEEHHHHHHCEEEEEEEECHHHHHCCC
PKGPSMDPEVKRLAMMVEDHPYSYKDFEGTIPAGNYGAGNVIVWDNGTYTSDEKTASDEK
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHH
QLLADLKKGRLSFVLKGKKLKGEFSLVKLHGKQENAWLLIKKQDKYASESDILEKDKSVI
HHHHHHHCCCEEEEEECCCCCCCEEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHH
SKRSLEELEKKSDKMTAKSEEKETKLKAIKKKPKAKTIKAEFIKPMLANTTEKPFDDEEW
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
IFENKYDGYRTIAVVNSDKTALFSRNKISFDINFKPIADELKKIDHTVVLDGEIVVENKS
EECCCCCCEEEEEEEECCCEEEEECCEEEEEECCCHHHHHHHHCCCEEEECCEEEEECCC
GRADFQLLQNYLKTGIGNLKYYVFDLLNLDGNEVTELSLLDRKELLKILFNKYSFSNIFY
CCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEHHHHHCHHHHHHHHHHHCCCCCEEE
SEHTIANGIEQFEKARKNNSEGIIAKKADSSYTAGGRSNNWLKIKISNEEEAIIIGITEP
CHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCEEEEEEECC
KNSRKYFGAILLGQYNGKNLQYIGKCGTGFTEAVLKELYTKLKPLFTDQSPLQEKVPLRD
CCCCEEEEEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHH
TIQWVKPKLVCQVKYSEWTQDNNLRHPVYLGLRIDKKAQEVVFNGNDNTKTINHNQEKME
HHHHCCCEEEEEEECCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCEECCCCHHHHH
NLKEHTTENDYDLKIGKTILHLTNQNKIYFPQDGITKGDIIQYYNEAAPLMLPYLKDRPE
HHHHHCCCCCCEEEECCEEEEEECCCEEEECCCCCCCCHHHHHHHCCCCEEEHHHHCCCH
SMNRFPNGIDSPGFYQKDIDADKTPKWLKTKKIFSESNDADVNYLICNDKETLLYMANLG
HHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCC
CIEINPWNSTIKNISNPDWLVIDLDPAKEDDFKSVIETALVVKEVMDELQTECLCKTSGA
EEEECCCCHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCC
SGLHIYIPLGAQYDYDSIKILAELIAKEVHTRLPKTTSIERSIKKRKNKLYIDFLQNRRG
CCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEHHHCCCC
QTLAAPYSVRPQPGATVSTPLEWNEVNEKLHPSQFTIKNVLQRFEKKGDLWKPVLSKGAN
CEEECCCCCCCCCCCEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCC
IKKIIKKLEEKQLEN
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
PMSLSKYNEKRDFKQTREPKGKVEKSANELIFVVQKHAASHLHYDFRLEMNGVLKSWAV
CCCCHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEEHHHHHHCEEEEEEEECHHHHHCCC
PKGPSMDPEVKRLAMMVEDHPYSYKDFEGTIPAGNYGAGNVIVWDNGTYTSDEKTASDEK
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHH
QLLADLKKGRLSFVLKGKKLKGEFSLVKLHGKQENAWLLIKKQDKYASESDILEKDKSVI
HHHHHHHCCCEEEEEECCCCCCCEEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHH
SKRSLEELEKKSDKMTAKSEEKETKLKAIKKKPKAKTIKAEFIKPMLANTTEKPFDDEEW
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
IFENKYDGYRTIAVVNSDKTALFSRNKISFDINFKPIADELKKIDHTVVLDGEIVVENKS
EECCCCCCEEEEEEEECCCEEEEECCEEEEEECCCHHHHHHHHCCCEEEECCEEEEECCC
GRADFQLLQNYLKTGIGNLKYYVFDLLNLDGNEVTELSLLDRKELLKILFNKYSFSNIFY
CCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEHHHHHCHHHHHHHHHHHCCCCCEEE
SEHTIANGIEQFEKARKNNSEGIIAKKADSSYTAGGRSNNWLKIKISNEEEAIIIGITEP
CHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCEEEEEEECC
KNSRKYFGAILLGQYNGKNLQYIGKCGTGFTEAVLKELYTKLKPLFTDQSPLQEKVPLRD
CCCCEEEEEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHH
TIQWVKPKLVCQVKYSEWTQDNNLRHPVYLGLRIDKKAQEVVFNGNDNTKTINHNQEKME
HHHHCCCEEEEEEECCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCEECCCCHHHHH
NLKEHTTENDYDLKIGKTILHLTNQNKIYFPQDGITKGDIIQYYNEAAPLMLPYLKDRPE
HHHHHCCCCCCEEEECCEEEEEECCCEEEECCCCCCCCHHHHHHHCCCCEEEHHHHCCCH
SMNRFPNGIDSPGFYQKDIDADKTPKWLKTKKIFSESNDADVNYLICNDKETLLYMANLG
HHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCC
CIEINPWNSTIKNISNPDWLVIDLDPAKEDDFKSVIETALVVKEVMDELQTECLCKTSGA
EEEECCCCHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCC
SGLHIYIPLGAQYDYDSIKILAELIAKEVHTRLPKTTSIERSIKKRKNKLYIDFLQNRRG
CCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEHHHCCCC
QTLAAPYSVRPQPGATVSTPLEWNEVNEKLHPSQFTIKNVLQRFEKKGDLWKPVLSKGAN
CEEECCCCCCCCCCCEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCC
IKKIIKKLEEKQLEN
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]