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The map label for this gene is bepF [H]

Identifier: 146300982

GI number: 146300982

Start: 3856755

End: 3857861

Strand: Direct

Name: bepF [H]

Synonym: Fjoh_3238

Alternate gene names: 146300982

Gene position: 3856755-3857861 (Clockwise)

Preceding gene: 146300981

Following gene: 146300983

Centisome position: 63.26

GC content: 36.5

Gene sequence:

>1107_bases
ATGAGCATTAAAAACAATTCATTTTTCATCTCTATTTTATCACTGTTCGTTCTGGTCTCGTGCGGTGATAAAGCCAAAAA
AAATTCAGATAAAATCAAAACACTGCCCGTTTATAAGGTGACTTTGAGAGATACCGTGGTTTCTAACCGATTTGTTGCCG
ATGTTCACGCCAAAAACAATGTCGAAATTCACGCTCGTATTCCCGGATTACTCGATAAAGTATATGTAAGCGAAGGACAA
AAAGTAAAAAAAGGACAAGTCCTGTTTAAAATAAGCGATGTAGAACTCCAAATACAACTTTTAAAAGCCGAAGCTGTTTA
TAAAAGCAGTATGGCCGATTTAAGAATCGCAACCGTTGAACTGGAACAAGCCCAGACCCTTTTTAATAAAAAAGTAATTG
CCGATAAGGAATTAGAATTATCTAAAGCAAAACACGATGCAGCTTCTGCTAAAGTGGCTCACGCATCTGCAGAAAGAAAA
GCGATCAATCAGCAGATTAGTTTTACCACAATCCGCGCTCCATTTGACGGAACGGTTGACCGAATTCCGTTTAAAGAAGG
AAGTCTGGTAGAAAACGGTTCTCTTTTAACCAACGTGTCACAGCTTGATTATATTTACGCTTATTTCTCAATTCCTGAAA
ATATTTATTTCCAGATGATGACAGATAAAAGCCTGAATACTCATGAAGATATTCAACTGGTTTTGCCAAACGGAATTGTC
TATAACCAAAAAGGAGAACTTAGAACTGCCGACGGAGATATCGACCGACAAACTGGTTCTATTCAATATAAAGCAAAATT
TGAAAATCCGCAGGGATTTATCAAACACGGAACATCTGGAAAACTTATTATTTCAGAACCCAAAACCAATGCGATCATAA
TTCCGCAAAAAGCAGTTTTTTCTATTCAGGACAAACAATTCGTATTTCTGGTAAATAAGGAAGGCAAAGTAAAAATGACC
AACGTTACTATTGGAAGTACTCTTGATGATGTATACATTCTAAACAAAGGTTTAAAAAACAACGATTTAATTGTTCAGGA
AGGCATTCAGTCTTTACGCGACGGCGATAAAATCAATATTAAAGAAACCCAGAACGTAAGCCTGTAA

Upstream 100 bases:

>100_bases
CGCAGCATTTCCATTTTATTTTCTAAACCCAATTAAAAACTCCCTGTAGGCTGTCTATAAGGGAGAGAATCTATTTATTT
ATTATTATAACAAATTAATC

Downstream 100 bases:

>100_bases
TTATACATTATTAAAAAGATTTCGAAATGATAGAAATGTTTATCAAAAGAAAAATATTATCATTAATCATCTCGGTTATG
ATAGTACTTTTAGGATTACT

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MSIKNNSFFISILSLFVLVSCGDKAKKNSDKIKTLPVYKVTLRDTVVSNRFVADVHAKNNVEIHARIPGLLDKVYVSEGQ
KVKKGQVLFKISDVELQIQLLKAEAVYKSSMADLRIATVELEQAQTLFNKKVIADKELELSKAKHDAASAKVAHASAERK
AINQQISFTTIRAPFDGTVDRIPFKEGSLVENGSLLTNVSQLDYIYAYFSIPENIYFQMMTDKSLNTHEDIQLVLPNGIV
YNQKGELRTADGDIDRQTGSIQYKAKFENPQGFIKHGTSGKLIISEPKTNAIIIPQKAVFSIQDKQFVFLVNKEGKVKMT
NVTIGSTLDDVYILNKGLKNNDLIVQEGIQSLRDGDKINIKETQNVSL

Sequences:

>Translated_368_residues
MSIKNNSFFISILSLFVLVSCGDKAKKNSDKIKTLPVYKVTLRDTVVSNRFVADVHAKNNVEIHARIPGLLDKVYVSEGQ
KVKKGQVLFKISDVELQIQLLKAEAVYKSSMADLRIATVELEQAQTLFNKKVIADKELELSKAKHDAASAKVAHASAERK
AINQQISFTTIRAPFDGTVDRIPFKEGSLVENGSLLTNVSQLDYIYAYFSIPENIYFQMMTDKSLNTHEDIQLVLPNGIV
YNQKGELRTADGDIDRQTGSIQYKAKFENPQGFIKHGTSGKLIISEPKTNAIIIPQKAVFSIQDKQFVFLVNKEGKVKMT
NVTIGSTLDDVYILNKGLKNNDLIVQEGIQSLRDGDKINIKETQNVSL
>Mature_367_residues
SIKNNSFFISILSLFVLVSCGDKAKKNSDKIKTLPVYKVTLRDTVVSNRFVADVHAKNNVEIHARIPGLLDKVYVSEGQK
VKKGQVLFKISDVELQIQLLKAEAVYKSSMADLRIATVELEQAQTLFNKKVIADKELELSKAKHDAASAKVAHASAERKA
INQQISFTTIRAPFDGTVDRIPFKEGSLVENGSLLTNVSQLDYIYAYFSIPENIYFQMMTDKSLNTHEDIQLVLPNGIVY
NQKGELRTADGDIDRQTGSIQYKAKFENPQGFIKHGTSGKLIISEPKTNAIIIPQKAVFSIQDKQFVFLVNKEGKVKMTN
VTIGSTLDDVYILNKGLKNNDLIVQEGIQSLRDGDKINIKETQNVSL

Specific function: May contribute to resistance to some drugs, such as deoxycholate, sodium dodecyl sulfate and nalidixic acid, in the absence of BepD and BepE [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789665, Length=374, Percent_Identity=27.2727272727273, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1789929, Length=356, Percent_Identity=25.2808988764045, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786668, Length=367, Percent_Identity=25.6130790190736, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI87082036, Length=325, Percent_Identity=25.2307692307692, Blast_Score=96, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41041; Mature: 40910

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKNNSFFISILSLFVLVSCGDKAKKNSDKIKTLPVYKVTLRDTVVSNRFVADVHAKNN
CCCCCCCHHHHHHHHHHEEECCCCCCCCCCCEEEEEEEEEEEEHHHHCCCEEEEEECCCC
VEIHARIPGLLDKVYVSEGQKVKKGQVLFKISDVELQIQLLKAEAVYKSSMADLRIATVE
EEEEEECCCHHHHHHHCCCCEEECCEEEEEEECCEEEEEEEEHHHHHHHCCCCEEEEEEE
LEQAQTLFNKKVIADKELELSKAKHDAASAKVAHASAERKAINQQISFTTIRAPFDGTVD
HHHHHHHHHHHEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCC
RIPFKEGSLVENGSLLTNVSQLDYIYAYFSIPENIYFQMMTDKSLNTHEDIQLVLPNGIV
CCCCCCCCEEECCCCEEEHHHHEEEEEEEECCCCEEEEEEECCCCCCCCCEEEEECCCEE
YNQKGELRTADGDIDRQTGSIQYKAKFENPQGFIKHGTSGKLIISEPKTNAIIIPQKAVF
ECCCCCEEECCCCCCCCCCCEEEEEEECCCCHHEEECCCCCEEEECCCCCEEEEECHHEE
SIQDKQFVFLVNKEGKVKMTNVTIGSTLDDVYILNKGLKNNDLIVQEGIQSLRDGDKINI
EECCCEEEEEECCCCCEEEEEEEECCCCCEEEEECCCCCCCCEEHHHHHHHHHCCCEEEE
KETQNVSL
ECCCCCCC
>Mature Secondary Structure 
SIKNNSFFISILSLFVLVSCGDKAKKNSDKIKTLPVYKVTLRDTVVSNRFVADVHAKNN
CCCCCCHHHHHHHHHHEEECCCCCCCCCCCEEEEEEEEEEEEHHHHCCCEEEEEECCCC
VEIHARIPGLLDKVYVSEGQKVKKGQVLFKISDVELQIQLLKAEAVYKSSMADLRIATVE
EEEEEECCCHHHHHHHCCCCEEECCEEEEEEECCEEEEEEEEHHHHHHHCCCCEEEEEEE
LEQAQTLFNKKVIADKELELSKAKHDAASAKVAHASAERKAINQQISFTTIRAPFDGTVD
HHHHHHHHHHHEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCC
RIPFKEGSLVENGSLLTNVSQLDYIYAYFSIPENIYFQMMTDKSLNTHEDIQLVLPNGIV
CCCCCCCCEEECCCCEEEHHHHEEEEEEEECCCCEEEEEEECCCCCCCCCEEEEECCCEE
YNQKGELRTADGDIDRQTGSIQYKAKFENPQGFIKHGTSGKLIISEPKTNAIIIPQKAVF
ECCCCCEEECCCCCCCCCCCEEEEEEECCCCHHEEECCCCCEEEECCCCCEEEEECHHEE
SIQDKQFVFLVNKEGKVKMTNVTIGSTLDDVYILNKGLKNNDLIVQEGIQSLRDGDKINI
EECCCEEEEEECCCCCEEEEEEEECCCCCEEEEECCCCCCCCEEHHHHHHHHHCCCEEEE
KETQNVSL
ECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]