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The map label for this gene is ape2 [H]

Identifier: 146300616

GI number: 146300616

Start: 3403235

End: 3404890

Strand: Reverse

Name: ape2 [H]

Synonym: Fjoh_2867

Alternate gene names: 146300616

Gene position: 3404890-3403235 (Counterclockwise)

Preceding gene: 146300617

Following gene: 146300614

Centisome position: 55.85

GC content: 34.36

Gene sequence:

>1656_bases
ATGAAAAATTACTTTGGAAGCATTTTAACTGCTTTTCTAATTGGTTTTACTGCCAATGCTCAGGGACTTTTAAATAAGTC
AGAAACCGTTTTTACACATCAGGATACTTTACGCGGAAGCATCACAAAAGAAAGAGCTTGGTGGGATTTGAAATATTATC
ACCTTGATGTAAAAGTGAATCCAAAAGAAAAATCAATCTCAGGTTCTAATACAGTTCGTTATACTGTTTTAACAGAAAAT
AACCGTATGCAGATTGATTTGCAGGAACCAATGAACATTACTAAAGTAACGCAGAACGGAAAAGAATTAAAATTTGAAAG
AGACGGAAACGCATTTTTCATCACTTTAAACGAAAAACAAAAAGTTGGCGATACAAAAGAAATTGTAGTATCATTTAACG
GAAAACCTAAAGAAGCGGTAAGAGCACCATGGGACGGCGGTTTTTCTTGGAAAAAAGATAAAAACGGAAAAGATTTTATT
GCTACATCTTGCCAGGGTTTAGGAGCGAGCGTTTGGTGGCCGTGTAAAGACCATATGTATGATGAAGTAGAAAATATGCT
TATCAGCGTTAATGTTCCGGGAGATTTAACAGAGGTTTCTAACGGAAGATTACAAAGCGTTAAAAAAGAAAAAGACGGAA
CGAAAACTTTCAATTGGTATGTTGCCAATCCTATCAATAATTACGGTGTAAACATCAATATTGGTGATTACGTTAATTTT
TCAGAAGTTTTTAAAGGCGAAAAAGGAAATTTAGACTGTAATTATTATGTTTTAAGAGACAATCTGGCTTTGGCGAAAGA
GCAGTTTAAAGATGCGCCAAAAATGCTGAAAGCTTTTGAAAACTGGTTCGGGCCTTATCCGTTCTACGAAGACAGTTATA
AATTGGTTGAAGTTCCGTATTTAGGAATGGAGCACCAAAGTTCTGTTACATACGGAAATCAATATAAAAACGGTTATTTA
GGGCGTGATTTAAGCGGAACGGGCTGGGGATTAAAGTTTGATTTTATCATCATTCACGAATCGGGTCACGAATGGTACGC
TAACAATATTACTTACAAAGATATTGCTGATATGTGGGTTCACGAGAGTTTTACAAACTATTCTGAAAGTCTTTTTGTGG
AGTATTATTATGGAAAAGATGCCGGAGCAGAATATGTAATTGGATGTAGAAAAAATATTAAAAATGATACTCCAATCATC
GGACATTATGATGTAAACAATGAAGGTTCTGGCGATATGTATCCAAAAGGAGCTACAATGCTTCATATGATTCGTCAGGT
AATAAATGATGATGCTAAATGGAAATCGATTTTAAGAGGCATGAACAAAACGTTTTACCATCAAACGGTTACTGGTAAAC
AAATTCAGGATTATATTAACGAACAATCCGGAATTAACTTCAACAGAGTTTTTGCTCAATATTTAACTACAACTCAAATT
CCGGTTTTTGAATATATGTTTAAAAACGGAACTTTCGGGTACCACTGGACAAACTGTGTTTCTAAATTTGATATGCCGGT
AAGAGTAAAATTAAACGGTGTTGAAACCTGGCTGAAACCAACAACAGAATGGCAGTCAGTAAAAACAGATAATGAAGACA
GAAAAATAGAAGTTGATAAAGATTTTTATGTTACGACTTCTAATATTGTAGAATAA

Upstream 100 bases:

>100_bases
TTTTATGAAGAAATCATAAAATTTTAGAATTCTTAATCCGAATGTTTACATTTGTGACAGATTAAGTTCGAATACTTTAT
TTATTTTATAATTCTAACCA

Downstream 100 bases:

>100_bases
ATTCTTTTAATTTTCAATATACAAAATCCCAAATTCCATCCCGATAGTTATCAGGAGGAATTTGGGATTTTTACGTTAGT
AAACCCGACAGGTTTTTAAA

Product: peptidase M1, membrane alanine aminopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MKNYFGSILTAFLIGFTANAQGLLNKSETVFTHQDTLRGSITKERAWWDLKYYHLDVKVNPKEKSISGSNTVRYTVLTEN
NRMQIDLQEPMNITKVTQNGKELKFERDGNAFFITLNEKQKVGDTKEIVVSFNGKPKEAVRAPWDGGFSWKKDKNGKDFI
ATSCQGLGASVWWPCKDHMYDEVENMLISVNVPGDLTEVSNGRLQSVKKEKDGTKTFNWYVANPINNYGVNINIGDYVNF
SEVFKGEKGNLDCNYYVLRDNLALAKEQFKDAPKMLKAFENWFGPYPFYEDSYKLVEVPYLGMEHQSSVTYGNQYKNGYL
GRDLSGTGWGLKFDFIIIHESGHEWYANNITYKDIADMWVHESFTNYSESLFVEYYYGKDAGAEYVIGCRKNIKNDTPII
GHYDVNNEGSGDMYPKGATMLHMIRQVINDDAKWKSILRGMNKTFYHQTVTGKQIQDYINEQSGINFNRVFAQYLTTTQI
PVFEYMFKNGTFGYHWTNCVSKFDMPVRVKLNGVETWLKPTTEWQSVKTDNEDRKIEVDKDFYVTTSNIVE

Sequences:

>Translated_551_residues
MKNYFGSILTAFLIGFTANAQGLLNKSETVFTHQDTLRGSITKERAWWDLKYYHLDVKVNPKEKSISGSNTVRYTVLTEN
NRMQIDLQEPMNITKVTQNGKELKFERDGNAFFITLNEKQKVGDTKEIVVSFNGKPKEAVRAPWDGGFSWKKDKNGKDFI
ATSCQGLGASVWWPCKDHMYDEVENMLISVNVPGDLTEVSNGRLQSVKKEKDGTKTFNWYVANPINNYGVNINIGDYVNF
SEVFKGEKGNLDCNYYVLRDNLALAKEQFKDAPKMLKAFENWFGPYPFYEDSYKLVEVPYLGMEHQSSVTYGNQYKNGYL
GRDLSGTGWGLKFDFIIIHESGHEWYANNITYKDIADMWVHESFTNYSESLFVEYYYGKDAGAEYVIGCRKNIKNDTPII
GHYDVNNEGSGDMYPKGATMLHMIRQVINDDAKWKSILRGMNKTFYHQTVTGKQIQDYINEQSGINFNRVFAQYLTTTQI
PVFEYMFKNGTFGYHWTNCVSKFDMPVRVKLNGVETWLKPTTEWQSVKTDNEDRKIEVDKDFYVTTSNIVE
>Mature_551_residues
MKNYFGSILTAFLIGFTANAQGLLNKSETVFTHQDTLRGSITKERAWWDLKYYHLDVKVNPKEKSISGSNTVRYTVLTEN
NRMQIDLQEPMNITKVTQNGKELKFERDGNAFFITLNEKQKVGDTKEIVVSFNGKPKEAVRAPWDGGFSWKKDKNGKDFI
ATSCQGLGASVWWPCKDHMYDEVENMLISVNVPGDLTEVSNGRLQSVKKEKDGTKTFNWYVANPINNYGVNINIGDYVNF
SEVFKGEKGNLDCNYYVLRDNLALAKEQFKDAPKMLKAFENWFGPYPFYEDSYKLVEVPYLGMEHQSSVTYGNQYKNGYL
GRDLSGTGWGLKFDFIIIHESGHEWYANNITYKDIADMWVHESFTNYSESLFVEYYYGKDAGAEYVIGCRKNIKNDTPII
GHYDVNNEGSGDMYPKGATMLHMIRQVINDDAKWKSILRGMNKTFYHQTVTGKQIQDYINEQSGINFNRVFAQYLTTTQI
PVFEYMFKNGTFGYHWTNCVSKFDMPVRVKLNGVETWLKPTTEWQSVKTDNEDRKIEVDKDFYVTTSNIVE

Specific function: Unknown

COG id: COG0308

COG function: function code E; Aminopeptidase N

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M1 family [H]

Homologues:

Organism=Homo sapiens, GI94818891, Length=348, Percent_Identity=22.9885057471264, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI94818901, Length=348, Percent_Identity=22.9885057471264, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001930
- InterPro:   IPR014782 [H]

Pfam domain/function: PF01433 Peptidase_M1 [H]

EC number: NA

Molecular weight: Translated: 63561; Mature: 63561

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNYFGSILTAFLIGFTANAQGLLNKSETVFTHQDTLRGSITKERAWWDLKYYHLDVKVN
CCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHCCCCCCCCEEEEEEEEEEEEEEC
PKEKSISGSNTVRYTVLTENNRMQIDLQEPMNITKVTQNGKELKFERDGNAFFITLNEKQ
CCCCCCCCCCEEEEEEEECCCEEEEEECCCCCEEEECCCCCEEEEEECCCEEEEEECCCH
KVGDTKEIVVSFNGKPKEAVRAPWDGGFSWKKDKNGKDFIATSCQGLGASVWWPCKDHMY
HCCCCEEEEEEECCCCHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEECCCHHHHH
DEVENMLISVNVPGDLTEVSNGRLQSVKKEKDGTKTFNWYVANPINNYGVNINIGDYVNF
HHHCCEEEEEECCCCCHHCCCCHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEECCCCCH
SEVFKGEKGNLDCNYYVLRDNLALAKEQFKDAPKMLKAFENWFGPYPFYEDSYKLVEVPY
HHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECC
LGMEHQSSVTYGNQYKNGYLGRDLSGTGWGLKFDFIIIHESGHEWYANNITYKDIADMWV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEEECCCCHHHHHHHHH
HESFTNYSESLFVEYYYGKDAGAEYVIGCRKNIKNDTPIIGHYDVNNEGSGDMYPKGATM
HHHHCCCCCEEEEEEEECCCCCCEEEEEEHHCCCCCCCEEEEEECCCCCCCCCCCCCHHH
LHMIRQVINDDAKWKSILRGMNKTFYHQTVTGKQIQDYINEQSGINFNRVFAQYLTTTQI
HHHHHHHHCCCHHHHHHHHHCCHHHEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
PVFEYMFKNGTFGYHWTNCVSKFDMPVRVKLNGVETWLKPTTEWQSVKTDNEDRKIEVDK
HHHHHHHCCCCCCCHHHHHHHHCCCCEEEEECCCHHCCCCCCCHHHCCCCCCCCEEEECC
DFYVTTSNIVE
CEEEECHHHCC
>Mature Secondary Structure
MKNYFGSILTAFLIGFTANAQGLLNKSETVFTHQDTLRGSITKERAWWDLKYYHLDVKVN
CCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHCCCCCCCCEEEEEEEEEEEEEEC
PKEKSISGSNTVRYTVLTENNRMQIDLQEPMNITKVTQNGKELKFERDGNAFFITLNEKQ
CCCCCCCCCCEEEEEEEECCCEEEEEECCCCCEEEECCCCCEEEEEECCCEEEEEECCCH
KVGDTKEIVVSFNGKPKEAVRAPWDGGFSWKKDKNGKDFIATSCQGLGASVWWPCKDHMY
HCCCCEEEEEEECCCCHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEECCCHHHHH
DEVENMLISVNVPGDLTEVSNGRLQSVKKEKDGTKTFNWYVANPINNYGVNINIGDYVNF
HHHCCEEEEEECCCCCHHCCCCHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEECCCCCH
SEVFKGEKGNLDCNYYVLRDNLALAKEQFKDAPKMLKAFENWFGPYPFYEDSYKLVEVPY
HHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECC
LGMEHQSSVTYGNQYKNGYLGRDLSGTGWGLKFDFIIIHESGHEWYANNITYKDIADMWV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEEECCCCHHHHHHHHH
HESFTNYSESLFVEYYYGKDAGAEYVIGCRKNIKNDTPIIGHYDVNNEGSGDMYPKGATM
HHHHCCCCCEEEEEEEECCCCCCEEEEEEHHCCCCCCCEEEEEECCCCCCCCCCCCCHHH
LHMIRQVINDDAKWKSILRGMNKTFYHQTVTGKQIQDYINEQSGINFNRVFAQYLTTTQI
HHHHHHHHCCCHHHHHHHHHCCHHHEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
PVFEYMFKNGTFGYHWTNCVSKFDMPVRVKLNGVETWLKPTTEWQSVKTDNEDRKIEVDK
HHHHHHHCCCCCCCHHHHHHHHCCCCEEEEECCCHHCCCCCCCHHHCCCCCCCCEEEECC
DFYVTTSNIVE
CEEEECHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]