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The map label for this gene is recQ [H]

Identifier: 146300558

GI number: 146300558

Start: 3341092

End: 3343209

Strand: Reverse

Name: recQ [H]

Synonym: Fjoh_2808

Alternate gene names: 146300558

Gene position: 3343209-3341092 (Counterclockwise)

Preceding gene: 146300559

Following gene: 146300553

Centisome position: 54.83

GC content: 34.84

Gene sequence:

>2118_bases
ATGAATTCAGAACTACTACACGCCAAACTAAAGGAAAATTTTGGATTTGAAAAATTCAGACCCAATCAGGAGACTATCAT
TACTACAGTATTGTCTGGTAATGATGCACTGGCAATTATGCCAACCGGAGGAGGAAAATCAATATGTTTTCAATTGCCAG
CCCTTGTACTGCCAGGAATAACGATTGTAATTTCACCTCTGATCGCTTTAATGAAAGATCAGGTTGACAGTTTAAAATCA
AATGGTATTTCAGCTTGTTACATCAACAGTAGCCAATCTTCAGAAGAACAGCAGTATTATATAGACAATTTAAAAACGAA
TACTTTTAAACTTGTTTACATTGCGCCTGAAAGTTTATCGTATTTAGACACCATTTTTAGCGAATTAACTATTAGTTTAA
TCGCAATCGACGAAGCACATTGTATTTCATCCTGGGGACACGATTTCAGGCCGGCTTATACCAATTTGGGTTATTTAAAA
AACCGCTTCCCTTCTACTCCTGTTTTGGCTTTAACAGCAACTGCCGATAAAGCGACACGTGTTGATATTACAAAACAGCT
CAATTTAAAAAATCCGAAAACTTTTGTAGCTTCTTTTGACCGAAAAAATTTAAGTCTTGAAGTACGCCCTGCATTAGACC
GTGTAAAACAAATTATTGACTTTGTAGAAAATAAGCCAAATGAATCCGGAATAATCTATTGTTTAAGCCGAAAAACAACC
GAAGAACTTGCTGAAAAATTAGCAAAAAACGGAATTGCAGCAAAAGCCTATCATGCAGGCTTAGACAATACAACCCGTGC
CAAAACACAAGATGAATTTATAAACGACGATTGTCAGGTTGTATGTGCCACGATTGCATTTGGGATGGGAATTGATAAAT
CAAATGTACGATGGGTAATTCATTATAATCTTCCTAAAAACATAGAAGGGTATTATCAGGAAATTGGCCGTGCGGGTCGT
GACGGCCTTCCGGCTGAAACGGTTTTGTTTGAAAGTTATGCAGATGTAATTCAACTTCAAAAATTTGCTTCGGATGGATT
GAATGCAGATGTGCAGCTTGCCAAATTAGACCGAATGAAACAATATGCCGATGCTGTAAGCTGCAGACGAAAGATTCTGC
TTTCTTATTTCGGTGAATTGGTGACAGAGAATTGCGGTAATTGTGATATTTGCAAAAATCCGCCAACTTTTTTCGATGGG
ACGATTCTCGCACAAAAAGCCCTTTCTGCAATTACAAGATTACAGGAGTCTGAGCCTTTGGCAGTAATTGTTGATTTTTT
AAGAGGCTCGAGAAACGCGTATATCTACGAAAAAAATTATCAGGAGCTAAAAACGTACGGAATTGGCGCTGACATTTCGT
GGTACGACTGGAATCAATATTTAATTCAGCTTATTAATTTAGGATATTGCGAAATTGCCTTTCATCAGCATAATAAAATT
TTATTGACGCCTTTTGCTAAAAAAGTTTTATTTGAAGGCGAAAAAGTAAAGCTTACAACAGTTGTCAAGAAAGTAATTGA
TAAAAATGAAATAAAACAAGAGAAAGCAAAAGCTGTTAAAAATTCTCTTTTTGAAACCCTTAGAAAATTACGTTATGAAA
TTGCTAAAGAAGAAGAAGTTCCGGCATATGTAATTTTCAGCGATGCATCTTTGAGACAAATGGAAATCTTAAGACCAATG
AGCGATGAAGAATTTCTGGCTGTTGAAGGTGTTGGAAAAGCAAAACTTGAAAAATACGGTGCAGAATTTATCAATGCAAT
TATTGAGTTTCAAAGAAATAAATCGGTTGTTAAAAAAGAAAAAAAAGACAGCACTTATAAAAAAACGCTAGAATTATTTC
AAAGCGGTAGTTCTGTCGAAGAAATTGCAGAAAGAAGAAGCATCAGCCAGACAACTGTAGTTTCTCATATTGCAAAATTA
TATGTAGACGGATACGATTTAGATTTAAGTCAGTTTGTTTCTGATGAAGAAATTGCTGCAATAGAAAAAGCACAAATTGA
ATTAGAAAAGCCAAGTGCATTAAAGCCTTATTTCGATTATTTTGAAGAAAAAATGTCTTATGATAAAATTAGATTTGGTT
TAGCAGTTGTTGAAAGAAAATATCAAACAATTCAATAA

Upstream 100 bases:

>100_bases
TTTTTTTATGAAATTAGATTGGTAAATAAAATTATTTAAATTATAAGAAAAATACTATATTTATATTTTGGATTTAGTTC
CAGATATAAATATTCGCCGC

Downstream 100 bases:

>100_bases
ATGCCCTTTTGATCATAAAAAAAATCCTGTGAATATTCACAGGATTTTTTTATGTATAAGCTTTACAAATATCTTTCTTT
AAAAACTTTTTGATGATGTT

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 705; Mature: 705

Protein sequence:

>705_residues
MNSELLHAKLKENFGFEKFRPNQETIITTVLSGNDALAIMPTGGGKSICFQLPALVLPGITIVISPLIALMKDQVDSLKS
NGISACYINSSQSSEEQQYYIDNLKTNTFKLVYIAPESLSYLDTIFSELTISLIAIDEAHCISSWGHDFRPAYTNLGYLK
NRFPSTPVLALTATADKATRVDITKQLNLKNPKTFVASFDRKNLSLEVRPALDRVKQIIDFVENKPNESGIIYCLSRKTT
EELAEKLAKNGIAAKAYHAGLDNTTRAKTQDEFINDDCQVVCATIAFGMGIDKSNVRWVIHYNLPKNIEGYYQEIGRAGR
DGLPAETVLFESYADVIQLQKFASDGLNADVQLAKLDRMKQYADAVSCRRKILLSYFGELVTENCGNCDICKNPPTFFDG
TILAQKALSAITRLQESEPLAVIVDFLRGSRNAYIYEKNYQELKTYGIGADISWYDWNQYLIQLINLGYCEIAFHQHNKI
LLTPFAKKVLFEGEKVKLTTVVKKVIDKNEIKQEKAKAVKNSLFETLRKLRYEIAKEEEVPAYVIFSDASLRQMEILRPM
SDEEFLAVEGVGKAKLEKYGAEFINAIIEFQRNKSVVKKEKKDSTYKKTLELFQSGSSVEEIAERRSISQTTVVSHIAKL
YVDGYDLDLSQFVSDEEIAAIEKAQIELEKPSALKPYFDYFEEKMSYDKIRFGLAVVERKYQTIQ

Sequences:

>Translated_705_residues
MNSELLHAKLKENFGFEKFRPNQETIITTVLSGNDALAIMPTGGGKSICFQLPALVLPGITIVISPLIALMKDQVDSLKS
NGISACYINSSQSSEEQQYYIDNLKTNTFKLVYIAPESLSYLDTIFSELTISLIAIDEAHCISSWGHDFRPAYTNLGYLK
NRFPSTPVLALTATADKATRVDITKQLNLKNPKTFVASFDRKNLSLEVRPALDRVKQIIDFVENKPNESGIIYCLSRKTT
EELAEKLAKNGIAAKAYHAGLDNTTRAKTQDEFINDDCQVVCATIAFGMGIDKSNVRWVIHYNLPKNIEGYYQEIGRAGR
DGLPAETVLFESYADVIQLQKFASDGLNADVQLAKLDRMKQYADAVSCRRKILLSYFGELVTENCGNCDICKNPPTFFDG
TILAQKALSAITRLQESEPLAVIVDFLRGSRNAYIYEKNYQELKTYGIGADISWYDWNQYLIQLINLGYCEIAFHQHNKI
LLTPFAKKVLFEGEKVKLTTVVKKVIDKNEIKQEKAKAVKNSLFETLRKLRYEIAKEEEVPAYVIFSDASLRQMEILRPM
SDEEFLAVEGVGKAKLEKYGAEFINAIIEFQRNKSVVKKEKKDSTYKKTLELFQSGSSVEEIAERRSISQTTVVSHIAKL
YVDGYDLDLSQFVSDEEIAAIEKAQIELEKPSALKPYFDYFEEKMSYDKIRFGLAVVERKYQTIQ
>Mature_705_residues
MNSELLHAKLKENFGFEKFRPNQETIITTVLSGNDALAIMPTGGGKSICFQLPALVLPGITIVISPLIALMKDQVDSLKS
NGISACYINSSQSSEEQQYYIDNLKTNTFKLVYIAPESLSYLDTIFSELTISLIAIDEAHCISSWGHDFRPAYTNLGYLK
NRFPSTPVLALTATADKATRVDITKQLNLKNPKTFVASFDRKNLSLEVRPALDRVKQIIDFVENKPNESGIIYCLSRKTT
EELAEKLAKNGIAAKAYHAGLDNTTRAKTQDEFINDDCQVVCATIAFGMGIDKSNVRWVIHYNLPKNIEGYYQEIGRAGR
DGLPAETVLFESYADVIQLQKFASDGLNADVQLAKLDRMKQYADAVSCRRKILLSYFGELVTENCGNCDICKNPPTFFDG
TILAQKALSAITRLQESEPLAVIVDFLRGSRNAYIYEKNYQELKTYGIGADISWYDWNQYLIQLINLGYCEIAFHQHNKI
LLTPFAKKVLFEGEKVKLTTVVKKVIDKNEIKQEKAKAVKNSLFETLRKLRYEIAKEEEVPAYVIFSDASLRQMEILRPM
SDEEFLAVEGVGKAKLEKYGAEFINAIIEFQRNKSVVKKEKKDSTYKKTLELFQSGSSVEEIAERRSISQTTVVSHIAKL
YVDGYDLDLSQFVSDEEIAAIEKAQIELEKPSALKPYFDYFEEKMSYDKIRFGLAVVERKYQTIQ

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=643, Percent_Identity=36.3919129082426, Blast_Score=347, Evalue=2e-95,
Organism=Homo sapiens, GI110735439, Length=507, Percent_Identity=38.2642998027613, Blast_Score=331, Evalue=2e-90,
Organism=Homo sapiens, GI169218196, Length=507, Percent_Identity=38.2642998027613, Blast_Score=331, Evalue=2e-90,
Organism=Homo sapiens, GI14591902, Length=405, Percent_Identity=40.2469135802469, Blast_Score=300, Evalue=4e-81,
Organism=Homo sapiens, GI14591904, Length=405, Percent_Identity=40.2469135802469, Blast_Score=300, Evalue=4e-81,
Organism=Homo sapiens, GI148612816, Length=422, Percent_Identity=38.3886255924171, Blast_Score=286, Evalue=6e-77,
Organism=Homo sapiens, GI51242943, Length=357, Percent_Identity=42.296918767507, Blast_Score=269, Evalue=6e-72,
Organism=Homo sapiens, GI51242947, Length=357, Percent_Identity=42.296918767507, Blast_Score=269, Evalue=7e-72,
Organism=Homo sapiens, GI284005309, Length=345, Percent_Identity=36.231884057971, Blast_Score=214, Evalue=3e-55,
Organism=Homo sapiens, GI164664518, Length=349, Percent_Identity=26.3610315186246, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI222352149, Length=333, Percent_Identity=24.9249249249249, Blast_Score=70, Evalue=8e-12,
Organism=Escherichia coli, GI48994977, Length=584, Percent_Identity=46.4041095890411, Blast_Score=549, Evalue=1e-157,
Organism=Escherichia coli, GI87082221, Length=344, Percent_Identity=24.1279069767442, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787016, Length=343, Percent_Identity=25.0728862973761, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25145561, Length=690, Percent_Identity=33.4782608695652, Blast_Score=348, Evalue=7e-96,
Organism=Caenorhabditis elegans, GI71987997, Length=465, Percent_Identity=38.494623655914, Blast_Score=307, Evalue=1e-83,
Organism=Caenorhabditis elegans, GI32564293, Length=801, Percent_Identity=29.5880149812734, Blast_Score=306, Evalue=2e-83,
Organism=Caenorhabditis elegans, GI71987993, Length=465, Percent_Identity=38.494623655914, Blast_Score=306, Evalue=2e-83,
Organism=Caenorhabditis elegans, GI17552866, Length=431, Percent_Identity=36.6589327146172, Blast_Score=266, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI17537549, Length=368, Percent_Identity=23.9130434782609, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71987143, Length=357, Percent_Identity=24.3697478991597, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17552114, Length=347, Percent_Identity=24.207492795389, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115533224, Length=343, Percent_Identity=23.6151603498542, Blast_Score=69, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=523, Percent_Identity=37.2848948374761, Blast_Score=343, Evalue=8e-95,
Organism=Saccharomyces cerevisiae, GI6320224, Length=374, Percent_Identity=22.4598930481283, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321360, Length=343, Percent_Identity=25.9475218658892, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320041, Length=330, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6324217, Length=346, Percent_Identity=21.9653179190751, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24646066, Length=635, Percent_Identity=36.3779527559055, Blast_Score=380, Evalue=1e-105,
Organism=Drosophila melanogaster, GI24664226, Length=451, Percent_Identity=36.8070953436807, Blast_Score=285, Evalue=8e-77,
Organism=Drosophila melanogaster, GI62472181, Length=451, Percent_Identity=36.8070953436807, Blast_Score=282, Evalue=5e-76,
Organism=Drosophila melanogaster, GI24664230, Length=451, Percent_Identity=36.8070953436807, Blast_Score=282, Evalue=5e-76,
Organism=Drosophila melanogaster, GI21358123, Length=353, Percent_Identity=35.4107648725212, Blast_Score=205, Evalue=1e-52,
Organism=Drosophila melanogaster, GI21355075, Length=347, Percent_Identity=23.9193083573487, Blast_Score=78, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 79694; Mature: 79694

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSELLHAKLKENFGFEKFRPNQETIITTVLSGNDALAIMPTGGGKSICFQLPALVLPGI
CCCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCH
TIVISPLIALMKDQVDSLKSNGISACYINSSQSSEEQQYYIDNLKTNTFKLVYIAPESLS
HHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHCCCCCEEEEEEECCCHHH
YLDTIFSELTISLIAIDEAHCISSWGHDFRPAYTNLGYLKNRFPSTPVLALTATADKATR
HHHHHHHHHHEEEEEECHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCE
VDITKQLNLKNPKTFVASFDRKNLSLEVRPALDRVKQIIDFVENKPNESGIIYCLSRKTT
EEHHHCCCCCCCHHHHEECCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCH
EELAEKLAKNGIAAKAYHAGLDNTTRAKTQDEFINDDCQVVCATIAFGMGIDKSNVRWVI
HHHHHHHHHCCCEEHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEE
HYNLPKNIEGYYQEIGRAGRDGLPAETVLFESYADVIQLQKFASDGLNADVQLAKLDRMK
EECCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
QYADAVSCRRKILLSYFGELVTENCGNCDICKNPPTFFDGTILAQKALSAITRLQESEPL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCH
AVIVDFLRGSRNAYIYEKNYQELKTYGIGADISWYDWNQYLIQLINLGYCEIAFHQHNKI
HHHHHHHHCCCCEEEEECCHHHHHHHCCCCCCEEECHHHHHHHHHHCCCEEEEEECCCEE
LLTPFAKKVLFEGEKVKLTTVVKKVIDKNEIKQEKAKAVKNSLFETLRKLRYEIAKEEEV
EECHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PAYVIFSDASLRQMEILRPMSDEEFLAVEGVGKAKLEKYGAEFINAIIEFQRNKSVVKKE
CEEEEECCCCHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH
KKDSTYKKTLELFQSGSSVEEIAERRSISQTTVVSHIAKLYVDGYDLDLSQFVSDEEIAA
HCCHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHH
IEKAQIELEKPSALKPYFDYFEEKMSYDKIRFGLAVVERKYQTIQ
HHHHHEEECCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNSELLHAKLKENFGFEKFRPNQETIITTVLSGNDALAIMPTGGGKSICFQLPALVLPGI
CCCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCH
TIVISPLIALMKDQVDSLKSNGISACYINSSQSSEEQQYYIDNLKTNTFKLVYIAPESLS
HHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHCCCCCEEEEEEECCCHHH
YLDTIFSELTISLIAIDEAHCISSWGHDFRPAYTNLGYLKNRFPSTPVLALTATADKATR
HHHHHHHHHHEEEEEECHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCE
VDITKQLNLKNPKTFVASFDRKNLSLEVRPALDRVKQIIDFVENKPNESGIIYCLSRKTT
EEHHHCCCCCCCHHHHEECCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCH
EELAEKLAKNGIAAKAYHAGLDNTTRAKTQDEFINDDCQVVCATIAFGMGIDKSNVRWVI
HHHHHHHHHCCCEEHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEE
HYNLPKNIEGYYQEIGRAGRDGLPAETVLFESYADVIQLQKFASDGLNADVQLAKLDRMK
EECCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
QYADAVSCRRKILLSYFGELVTENCGNCDICKNPPTFFDGTILAQKALSAITRLQESEPL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCH
AVIVDFLRGSRNAYIYEKNYQELKTYGIGADISWYDWNQYLIQLINLGYCEIAFHQHNKI
HHHHHHHHCCCCEEEEECCHHHHHHHCCCCCCEEECHHHHHHHHHHCCCEEEEEECCCEE
LLTPFAKKVLFEGEKVKLTTVVKKVIDKNEIKQEKAKAVKNSLFETLRKLRYEIAKEEEV
EECHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PAYVIFSDASLRQMEILRPMSDEEFLAVEGVGKAKLEKYGAEFINAIIEFQRNKSVVKKE
CEEEEECCCCHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH
KKDSTYKKTLELFQSGSSVEEIAERRSISQTTVVSHIAKLYVDGYDLDLSQFVSDEEIAA
HCCHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHH
IEKAQIELEKPSALKPYFDYFEEKMSYDKIRFGLAVVERKYQTIQ
HHHHHEEECCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]