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The map label for this gene is steT [H]

Identifier: 146300034

GI number: 146300034

Start: 2749059

End: 2750207

Strand: Reverse

Name: steT [H]

Synonym: Fjoh_2279

Alternate gene names: 146300034

Gene position: 2750207-2749059 (Counterclockwise)

Preceding gene: 146300035

Following gene: 146300032

Centisome position: 45.11

GC content: 34.2

Gene sequence:

>1149_bases
TTGCCTGAAAATATCATCCTAAAAAACAAATTCAAGAAATGTCAGATTCTCCAAAAAATCAATGGCGGATCTTATAATTA
TATTAAAAGAGCTTTGGGTGATTATGCCGGATTTCTTTCAGGATGGTACGATTATATTGTAAATGCCATCCCTCCTGCTT
TTTACTGTATTGTAATCAGCGAATACACCATTATTTTATTTCCGCAATTAGCACATTATTCTACCGTATTATCTATTTCT
TTATTGGTTGCATTTGTATTATTGCATTTAAGCGGCGTAAAAAACGGAAGCGTCATTCAGCAGATTACCAGTTTCTTAAA
AGTAATTTGCTTTGTAGCTTTGGTTACGGCTTGTTTTATGTATTCTGGAGTTGAAGTTCCGCCAATCAAAACAGATAATT
CAATTTTTCAAATCGGACTTATTTTCGGATTCTTCAAATCTTTACAGCTTATTATTGGGACTTACAACGGCTGGAACGGT
GTTTGTTTTTTTGCTGAAGAAAATGAAAATCCAAGCAAAAATATTCCGAAATCTTTGTACAGCGGCGTTCTGCTTGTTGT
AGCCATTTATATTTTGGTAAATGCAGCTTTTTTTCACGTTCTCCCAATCGAAACTATAGCAAAATCGAATCTGGCTGCTG
CCGATGTTGCAAAAATTCTTTTCGGTGACAGCGGAGCTAAAATCGTTACCATAATTTCTATTTTCTCCTTAATTAGTATT
TTGAATGCGTTTATGATGATTCCGCCAAGAATTTTGTACGGATTAAGTCGTGACGGATTTTTTATCGAAAAAGGAACTCA
AGTCAATAAAGGCGGAACACCAATTGTTGCGCTTTTGGTTTCATCATTTTTCAGTTTGTTTTTAATCTGCATTGGTTCTT
TTGAAGTCTTATTTTCTTTTGCAGCTTTTATCTCGATAATCGTTTGGGGACTGGCCTATTATTCACTTTTAAAACTAAGA
ACTACAGAACCGGATCTACCAAGACCCTATCGTTCTTTTTGGTATCCGTGGACAACTATAATAGCGATTATATTTTCTAT
CGCATTACTTGCTGGATTCATTTACAGCGACCCTAAAAGCTTTATTATTATTGTTGGAATTGCAATTGTTTCTTATCCTT
TGTTTTTGGTTTTGAAGAAACAAAAATAA

Upstream 100 bases:

>100_bases
ATTGAATTAGAGTTTTGATTTTATCCCAAGATTTTCAGTTTCACTAGAAAATCTTGGGATTTTTATTTTAAGCTCAATTA
TAATTCAATTAACACTATTT

Downstream 100 bases:

>100_bases
CATAATTTTGTCATTCCGAGGAACGAGGAATCACACATAAAACTCTGTACAGTGATTCTCCAATCTTTGTCGATTTCCGA
GTGTGATTCCTCGTTCCTCG

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MPENIILKNKFKKCQILQKINGGSYNYIKRALGDYAGFLSGWYDYIVNAIPPAFYCIVISEYTIILFPQLAHYSTVLSIS
LLVAFVLLHLSGVKNGSVIQQITSFLKVICFVALVTACFMYSGVEVPPIKTDNSIFQIGLIFGFFKSLQLIIGTYNGWNG
VCFFAEENENPSKNIPKSLYSGVLLVVAIYILVNAAFFHVLPIETIAKSNLAAADVAKILFGDSGAKIVTIISIFSLISI
LNAFMMIPPRILYGLSRDGFFIEKGTQVNKGGTPIVALLVSSFFSLFLICIGSFEVLFSFAAFISIIVWGLAYYSLLKLR
TTEPDLPRPYRSFWYPWTTIIAIIFSIALLAGFIYSDPKSFIIIVGIAIVSYPLFLVLKKQK

Sequences:

>Translated_382_residues
MPENIILKNKFKKCQILQKINGGSYNYIKRALGDYAGFLSGWYDYIVNAIPPAFYCIVISEYTIILFPQLAHYSTVLSIS
LLVAFVLLHLSGVKNGSVIQQITSFLKVICFVALVTACFMYSGVEVPPIKTDNSIFQIGLIFGFFKSLQLIIGTYNGWNG
VCFFAEENENPSKNIPKSLYSGVLLVVAIYILVNAAFFHVLPIETIAKSNLAAADVAKILFGDSGAKIVTIISIFSLISI
LNAFMMIPPRILYGLSRDGFFIEKGTQVNKGGTPIVALLVSSFFSLFLICIGSFEVLFSFAAFISIIVWGLAYYSLLKLR
TTEPDLPRPYRSFWYPWTTIIAIIFSIALLAGFIYSDPKSFIIIVGIAIVSYPLFLVLKKQK
>Mature_381_residues
PENIILKNKFKKCQILQKINGGSYNYIKRALGDYAGFLSGWYDYIVNAIPPAFYCIVISEYTIILFPQLAHYSTVLSISL
LVAFVLLHLSGVKNGSVIQQITSFLKVICFVALVTACFMYSGVEVPPIKTDNSIFQIGLIFGFFKSLQLIIGTYNGWNGV
CFFAEENENPSKNIPKSLYSGVLLVVAIYILVNAAFFHVLPIETIAKSNLAAADVAKILFGDSGAKIVTIISIFSLISIL
NAFMMIPPRILYGLSRDGFFIEKGTQVNKGGTPIVALLVSSFFSLFLICIGSFEVLFSFAAFISIIVWGLAYYSLLKLRT
TEPDLPRPYRSFWYPWTTIIAIIFSIALLAGFIYSDPKSFIIIVGIAIVSYPLFLVLKKQK

Specific function: Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family [H]

Homologues:

Organism=Homo sapiens, GI186910308, Length=376, Percent_Identity=27.9255319148936, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI186910306, Length=376, Percent_Identity=27.9255319148936, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI186910304, Length=376, Percent_Identity=27.9255319148936, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI115648063, Length=374, Percent_Identity=26.4705882352941, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI115648022, Length=374, Percent_Identity=26.4705882352941, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI7657683, Length=390, Percent_Identity=25.1282051282051, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI187423910, Length=341, Percent_Identity=26.099706744868, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI7657591, Length=341, Percent_Identity=26.099706744868, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI33286428, Length=370, Percent_Identity=25.1351351351351, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI33286430, Length=225, Percent_Identity=25.7777777777778, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI71999149, Length=349, Percent_Identity=25.214899713467, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI87082250, Length=367, Percent_Identity=23.1607629427793, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI2367353, Length=281, Percent_Identity=25.2669039145907, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1786302, Length=368, Percent_Identity=20.6521739130435, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790653, Length=319, Percent_Identity=21.3166144200627, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17540018, Length=331, Percent_Identity=28.0966767371601, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71982608, Length=165, Percent_Identity=30.9090909090909, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71982612, Length=165, Percent_Identity=30.9090909090909, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI32566699, Length=378, Percent_Identity=23.015873015873, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71995388, Length=259, Percent_Identity=25.4826254826255, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71995382, Length=259, Percent_Identity=25.4826254826255, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193208714, Length=169, Percent_Identity=33.1360946745562, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32566695, Length=169, Percent_Identity=33.1360946745562, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24651635, Length=342, Percent_Identity=25.1461988304094, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24651633, Length=342, Percent_Identity=25.1461988304094, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI21357367, Length=379, Percent_Identity=26.1213720316623, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641993, Length=178, Percent_Identity=27.5280898876405, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24641995, Length=178, Percent_Identity=27.5280898876405, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI45550968, Length=383, Percent_Identity=24.8041775456919, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19921172, Length=383, Percent_Identity=24.8041775456919, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221331183, Length=325, Percent_Identity=24.3076923076923, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI17647653, Length=325, Percent_Identity=24.3076923076923, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24664379, Length=325, Percent_Identity=24.3076923076923, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 42431; Mature: 42300

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPENIILKNKFKKCQILQKINGGSYNYIKRALGDYAGFLSGWYDYIVNAIPPAFYCIVIS
CCCCCEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
EYTIILFPQLAHYSTVLSISLLVAFVLLHLSGVKNGSVIQQITSFLKVICFVALVTACFM
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YSGVEVPPIKTDNSIFQIGLIFGFFKSLQLIIGTYNGWNGVCFFAEENENPSKNIPKSLY
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEECCCCCCCCCCHHHH
SGVLLVVAIYILVNAAFFHVLPIETIAKSNLAAADVAKILFGDSGAKIVTIISIFSLISI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LNAFMMIPPRILYGLSRDGFFIEKGTQVNKGGTPIVALLVSSFFSLFLICIGSFEVLFSF
HHHHHHCCHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAFISIIVWGLAYYSLLKLRTTEPDLPRPYRSFWYPWTTIIAIIFSIALLAGFIYSDPKS
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCC
FIIIVGIAIVSYPLFLVLKKQK
EEHHHHHHHHHHHHHHEEECCC
>Mature Secondary Structure 
PENIILKNKFKKCQILQKINGGSYNYIKRALGDYAGFLSGWYDYIVNAIPPAFYCIVIS
CCCCEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
EYTIILFPQLAHYSTVLSISLLVAFVLLHLSGVKNGSVIQQITSFLKVICFVALVTACFM
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YSGVEVPPIKTDNSIFQIGLIFGFFKSLQLIIGTYNGWNGVCFFAEENENPSKNIPKSLY
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEECCCCCCCCCCHHHH
SGVLLVVAIYILVNAAFFHVLPIETIAKSNLAAADVAKILFGDSGAKIVTIISIFSLISI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LNAFMMIPPRILYGLSRDGFFIEKGTQVNKGGTPIVALLVSSFFSLFLICIGSFEVLFSF
HHHHHHCCHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAFISIIVWGLAYYSLLKLRTTEPDLPRPYRSFWYPWTTIIAIIFSIALLAGFIYSDPKS
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCC
FIIIVGIAIVSYPLFLVLKKQK
EEHHHHHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]