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The map label for this gene is eryC1 [H]

Identifier: 146299993

GI number: 146299993

Start: 2691892

End: 2692992

Strand: Direct

Name: eryC1 [H]

Synonym: Fjoh_2237

Alternate gene names: 146299993

Gene position: 2691892-2692992 (Clockwise)

Preceding gene: 146299992

Following gene: 146299994

Centisome position: 44.15

GC content: 32.15

Gene sequence:

>1101_bases
ATGATTTCATTTCTGGATCTAAAAAAAATAAATCAGCCATACGAAACTGCTTTTCAGGAAAAACTGAAAACGGTTTTAGA
CAACGGCTGGTATATTTTAGGAAATGAAGTTGAAAATTTTGAAAAGGCTTTCGCTGAATATTGCCACTCTGAATATTGTA
TTGGAGTAGGGAATGGTTTTGATGCTTTGGTTTTAATTTTTAAAGGCTATATCGAACTCGGAATACTCAAAAAAGGTGAT
GAAGTTATAGTTCCGGCAAATACTTATATTGCCAGTATTCTGGCCATTCTGCAAGCCGATTTGATTCCTGTTTTGGTTGA
ACCAAGATTAGAAACCTACAATATAAATCCGGATTTAATTCCCGAAAAAATCACATCAAAAACAAAAGCCATTTTAGCCG
TTCATTTATACGGACAATTAGCTGAAATGGAGAAAATAAATGAAATTGCACAAAAACATAATCTTGTTGTTGTAGAAGAT
TGTGCACAATCTCATGGAGCAATTAACAATCAACAATCAACAATTAATAATTCAAAATCAGCATCTGCATACAGTTTTTA
TCCGGGGAAAAATTTAGGCTGTCTGGGCGATGGAGGAGCTGTAACAACAAATGATGCTGAATTGGCAAAAATGCTTTTTT
CACTTCGCAATTATGGATCCCAAAAAAAATATTATAATGATTATGTTGGTGTAAATTCGAGATTAGATGAATTACAGGCG
GGTTTCTTAAACCTAAAATTACCCAATTTAGACGCCGATAATCAGAAAAGAAGAAACATTGCAAAACGATATTCAGCTGA
AATAAAAAACGAAAAAATTATACTTCCTAATTGGGATTTTTCTAATAATCATGTTTTTCATTTGTTTGTTATTCGAACAA
AAAACAGAGATGATTTACAGAATTATTTAGCTCAAAATAATATTCAAACTGTTATTCATTATCCGGTTCCTCCGCACAAA
CAAAATGCTTTTCCAGAATGGAATACTTTGTCTTTTCCTATAACAGAGAAAATTCATAACGAAATTTTAAGTCTGCCTAT
GAGCCCGGTTCTGGAAGATCAAGAAGTTGATTTTATTGTGGAAGTTTTAAATAGGTATTAA

Upstream 100 bases:

>100_bases
AGAAAGTTTTGGAGCAGGCACGATAATTCATGATTTTTATGAAATCGAAACTTCAAATTATACTAAGTTAAATGGTATTT
TTGTCTAAAAACCAAAACCA

Downstream 100 bases:

>100_bases
TTTTAATTTGATAAAATGAAAAAATTAAAATTAACACTTAAAAAATACGTTCCTGAAACAATATGGATTTCGCTTATCAG
AGTTTATAATTTTACAAAGC

Product: DegT/DnrJ/EryC1/StrS aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MISFLDLKKINQPYETAFQEKLKTVLDNGWYILGNEVENFEKAFAEYCHSEYCIGVGNGFDALVLIFKGYIELGILKKGD
EVIVPANTYIASILAILQADLIPVLVEPRLETYNINPDLIPEKITSKTKAILAVHLYGQLAEMEKINEIAQKHNLVVVED
CAQSHGAINNQQSTINNSKSASAYSFYPGKNLGCLGDGGAVTTNDAELAKMLFSLRNYGSQKKYYNDYVGVNSRLDELQA
GFLNLKLPNLDADNQKRRNIAKRYSAEIKNEKIILPNWDFSNNHVFHLFVIRTKNRDDLQNYLAQNNIQTVIHYPVPPHK
QNAFPEWNTLSFPITEKIHNEILSLPMSPVLEDQEVDFIVEVLNRY

Sequences:

>Translated_366_residues
MISFLDLKKINQPYETAFQEKLKTVLDNGWYILGNEVENFEKAFAEYCHSEYCIGVGNGFDALVLIFKGYIELGILKKGD
EVIVPANTYIASILAILQADLIPVLVEPRLETYNINPDLIPEKITSKTKAILAVHLYGQLAEMEKINEIAQKHNLVVVED
CAQSHGAINNQQSTINNSKSASAYSFYPGKNLGCLGDGGAVTTNDAELAKMLFSLRNYGSQKKYYNDYVGVNSRLDELQA
GFLNLKLPNLDADNQKRRNIAKRYSAEIKNEKIILPNWDFSNNHVFHLFVIRTKNRDDLQNYLAQNNIQTVIHYPVPPHK
QNAFPEWNTLSFPITEKIHNEILSLPMSPVLEDQEVDFIVEVLNRY
>Mature_366_residues
MISFLDLKKINQPYETAFQEKLKTVLDNGWYILGNEVENFEKAFAEYCHSEYCIGVGNGFDALVLIFKGYIELGILKKGD
EVIVPANTYIASILAILQADLIPVLVEPRLETYNINPDLIPEKITSKTKAILAVHLYGQLAEMEKINEIAQKHNLVVVED
CAQSHGAINNQQSTINNSKSASAYSFYPGKNLGCLGDGGAVTTNDAELAKMLFSLRNYGSQKKYYNDYVGVNSRLDELQA
GFLNLKLPNLDADNQKRRNIAKRYSAEIKNEKIILPNWDFSNNHVFHLFVIRTKNRDDLQNYLAQNNIQTVIHYPVPPHK
QNAFPEWNTLSFPITEKIHNEILSLPMSPVLEDQEVDFIVEVLNRY

Specific function: Sensor protein that transfers the signal of environmental stimuli to the regulatory region of target genes to activate or repress transcription of erythromycin biosynthesis genes (Potential) [H]

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family [H]

Homologues:

Organism=Escherichia coli, GI145693159, Length=368, Percent_Identity=28.5326086956522, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI2367285, Length=299, Percent_Identity=31.438127090301, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01041 DegT_DnrJ_EryC1 [H]

EC number: NA

Molecular weight: Translated: 41545; Mature: 41545

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISFLDLKKINQPYETAFQEKLKTVLDNGWYILGNEVENFEKAFAEYCHSEYCIGVGNGF
CCCCCCHHHCCCHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHCCCCEEEECCCCH
DALVLIFKGYIELGILKKGDEVIVPANTYIASILAILQADLIPVLVEPRLETYNINPDLI
HHHHHHHHHHHHEEEEECCCEEEECCHHHHHHHHHHHHHCCHHEEECCCCEEECCCCCCC
PEKITSKTKAILAVHLYGQLAEMEKINEIAQKHNLVVVEDCAQSHGAINNQQSTINNSKS
CHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHCCCCCCCHHHCCCCCC
ASAYSFYPGKNLGCLGDGGAVTTNDAELAKMLFSLRNYGSQKKYYNDYVGVNSRLDELQA
CCEEEECCCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHC
GFLNLKLPNLDADNQKRRNIAKRYSAEIKNEKIILPNWDFSNNHVFHLFVIRTKNRDDLQ
CEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEEEEECCHHHHH
NYLAQNNIQTVIHYPVPPHKQNAFPEWNTLSFPITEKIHNEILSLPMSPVLEDQEVDFIV
HHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHH
EVLNRY
HHHHCC
>Mature Secondary Structure
MISFLDLKKINQPYETAFQEKLKTVLDNGWYILGNEVENFEKAFAEYCHSEYCIGVGNGF
CCCCCCHHHCCCHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHCCCCEEEECCCCH
DALVLIFKGYIELGILKKGDEVIVPANTYIASILAILQADLIPVLVEPRLETYNINPDLI
HHHHHHHHHHHHEEEEECCCEEEECCHHHHHHHHHHHHHCCHHEEECCCCEEECCCCCCC
PEKITSKTKAILAVHLYGQLAEMEKINEIAQKHNLVVVEDCAQSHGAINNQQSTINNSKS
CHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHCCCCCCCHHHCCCCCC
ASAYSFYPGKNLGCLGDGGAVTTNDAELAKMLFSLRNYGSQKKYYNDYVGVNSRLDELQA
CCEEEECCCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHC
GFLNLKLPNLDADNQKRRNIAKRYSAEIKNEKIILPNWDFSNNHVFHLFVIRTKNRDDLQ
CEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEEEEECCHHHHH
NYLAQNNIQTVIHYPVPPHKQNAFPEWNTLSFPITEKIHNEILSLPMSPVLEDQEVDFIV
HHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHH
EVLNRY
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2575703 [H]