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The map label for this gene is dsbD [H]

Identifier: 146299895

GI number: 146299895

Start: 2589197

End: 2591284

Strand: Direct

Name: dsbD [H]

Synonym: Fjoh_2139

Alternate gene names: 146299895

Gene position: 2589197-2591284 (Clockwise)

Preceding gene: 146299894

Following gene: 146299897

Centisome position: 42.47

GC content: 34.48

Gene sequence:

>2088_bases
ATGAACTTTAATCAAAATCATCGAGCGATACTTTCAAGAAGTATCTGGAATAAAATAACCGCCTTTTTACTGCTGTTCTT
TTTTACTTTAGCAGGAAATGCTCAAATTTTAGAGCCTGTAAAATGGACTTCTAAAATTGAGAAAAAAGGAAACAATGCCG
TCTTAATTTTTGATGGAACAATCGAAAAAGACTGGCACATGTATTCGCAGTTTACACCAGACGGCGGACCTCTTGCACTT
GAAATTTCTTTTAAAAACCAAAAAGGAAACTACGAATTAGTTGGAAAAGCAAAAGAAGGTAAAACGAGAACGGCTTATAA
TGACGTTTTTGGAGTAGATGAAACTTTTTTTGAAGGAAAAGCACATATTGAACAGGAAATAAAAATCATTAATCCGAATT
TAAAAACGGTAGATGTAGATTTTGATTTTCAGGTTTGTAAAGAAGTTTGTATCAATTCAAGCAAGAAATTCTCGATTGCT
GTTCCTTCAACTTTTAAAATAGATGAAGCCCTTCCTGTTGTATCAGAAGCAAAATTAGACGAAACAAAAACGGCTGCTTT
AGCAGTTGATACTATTAAAAAAGAAACAGCTGCAGCTGAAGATCAAACTGTAAAAGCTGAAAATGAAGCTAAAGAAGATA
TTCCGGCTCCTGCACCAGCAAGAAGTTTGTGGTCAATCTTTTTTATTGCATTTTTATCTGGATTTGCAGCATTGTTAACA
CCTTGCGTTTTCCCAATGATTCCTATGACGGTTAGTTTCTTTACGAAACAAAGTAAAAGTCGTGCAAAAGGGATTAGAAA
TGCTATTATTTATGGACTTTCTATTATTGCAATTTATGTGATTTTAGGACTTATAGTAACTAAAATATTTGGTGCCGATG
CCTTAAATGCTTTGTCTACAGATGTTTGGTTTAATCTGATTTTCTTTGTAATCTTAATCATTTTTGCTACTTCATTTTTG
GGTGCTTTCGAAATTATGCTTCCAAACTCATGGGCAAATAAAGCAGATCAGCAGGCAGATAAAGGAGGATTGATTGGGAT
ATTATTCATGGCTCTGGCTTTGGCAATTGTATCATTCTCTTGCACAGGACCAATTGTTGGGACTTTATTGGTTGAAGCTG
CTTCAAACGGAGGAATTGCTCCTGTAGTTGGAATGCTTGGTTTTTCATCGGCATTAGCGCTTCCATTTATGTTATTTGCG
ATGTTCCCGGGCTGGTTAAATTCACTGCCAAAATCTGGCGGATGGTTAAATACTGTAAAGGTAGTTTTAGGGTTTTTAGA
ATTAGCTTTAGCATTTAAATTTTTATCAAATGCTGATTTAGTTCTTCAATTGCATTTTTTAGAAAGAGAAGTTTTCATCG
CAATCTGGATTGCAATTTTTGGAGCTTTGACTTTATATTTATTCGGGAAAATTACCTTGCCTCATGATAGTCCAACGCAC
CATATTTCGGTTGGAAGATTGTATTTAGGATTACTTACTTTAGTGTTTACAATGTATTTAATTCCTGGACTTTGGGGAGC
ACCGTTAAAATTAATCAGCGCATTTCCGCCGCCGCCGCAATATAGCGAAAGTCCTTTTGGAGTAGGAGGTTCTGGTAACG
GAGCTGTTTCTTCAGAATCAATAAAAGGACTTCCTGAAGGTGCAGAATTAGGTCCGCATGGTATAATGGTTTTTCATGAT
TATGAAGATGGATTAGCTTATGCAAAAGAAATCAAAAAGCCAATTATGCTCGATTTTACAGGTTATGCCTGTGTAAACTG
TAGAAAAATGGAAAACAATGTTTGGTCAGAACCAACAATTCTTCCAATTCTAAAAAATGACGTGGTATTGATTTCGCTTT
ATGTAGATGATAAACGTGAATTGCCAAAAGAAGAACAATTTGTTACTAAATCCGCAGATAAAATCATTACAGTTGGAGAT
AAATGGACTGATTTCATGATTTCTAAATATAAAACAAATACACAGCCTTTATATGTGATTACAGATTTAGAAGGAAACAA
TTTAAATGCTTCTAAGCCAACAATAAGTTATGTAAGCGCAGATGAATATTTACATTGGCTGAAAGAAGGAATTTCTAACT
TTAAATAA

Upstream 100 bases:

>100_bases
CTTCTGATGATCAAATAGTCTGGATTGTTGGAATTAGACAGGACGAACGTTTTAAAATAAATAATACCACAAATAAAATA
CTTAAAATAGAATTGCAATA

Downstream 100 bases:

>100_bases
TCATTTAAGAATTAAGAATTAAGAATTAAGAATTAAGAATTAAGAATTAAGAATTAAGAATTAAGAATTAAGAATTAAGA
ATTAAGAATTAAGAATTAAG

Product: cytochrome c biogenesis protein, transmembrane region

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 695; Mature: 695

Protein sequence:

>695_residues
MNFNQNHRAILSRSIWNKITAFLLLFFFTLAGNAQILEPVKWTSKIEKKGNNAVLIFDGTIEKDWHMYSQFTPDGGPLAL
EISFKNQKGNYELVGKAKEGKTRTAYNDVFGVDETFFEGKAHIEQEIKIINPNLKTVDVDFDFQVCKEVCINSSKKFSIA
VPSTFKIDEALPVVSEAKLDETKTAALAVDTIKKETAAAEDQTVKAENEAKEDIPAPAPARSLWSIFFIAFLSGFAALLT
PCVFPMIPMTVSFFTKQSKSRAKGIRNAIIYGLSIIAIYVILGLIVTKIFGADALNALSTDVWFNLIFFVILIIFATSFL
GAFEIMLPNSWANKADQQADKGGLIGILFMALALAIVSFSCTGPIVGTLLVEAASNGGIAPVVGMLGFSSALALPFMLFA
MFPGWLNSLPKSGGWLNTVKVVLGFLELALAFKFLSNADLVLQLHFLEREVFIAIWIAIFGALTLYLFGKITLPHDSPTH
HISVGRLYLGLLTLVFTMYLIPGLWGAPLKLISAFPPPPQYSESPFGVGGSGNGAVSSESIKGLPEGAELGPHGIMVFHD
YEDGLAYAKEIKKPIMLDFTGYACVNCRKMENNVWSEPTILPILKNDVVLISLYVDDKRELPKEEQFVTKSADKIITVGD
KWTDFMISKYKTNTQPLYVITDLEGNNLNASKPTISYVSADEYLHWLKEGISNFK

Sequences:

>Translated_695_residues
MNFNQNHRAILSRSIWNKITAFLLLFFFTLAGNAQILEPVKWTSKIEKKGNNAVLIFDGTIEKDWHMYSQFTPDGGPLAL
EISFKNQKGNYELVGKAKEGKTRTAYNDVFGVDETFFEGKAHIEQEIKIINPNLKTVDVDFDFQVCKEVCINSSKKFSIA
VPSTFKIDEALPVVSEAKLDETKTAALAVDTIKKETAAAEDQTVKAENEAKEDIPAPAPARSLWSIFFIAFLSGFAALLT
PCVFPMIPMTVSFFTKQSKSRAKGIRNAIIYGLSIIAIYVILGLIVTKIFGADALNALSTDVWFNLIFFVILIIFATSFL
GAFEIMLPNSWANKADQQADKGGLIGILFMALALAIVSFSCTGPIVGTLLVEAASNGGIAPVVGMLGFSSALALPFMLFA
MFPGWLNSLPKSGGWLNTVKVVLGFLELALAFKFLSNADLVLQLHFLEREVFIAIWIAIFGALTLYLFGKITLPHDSPTH
HISVGRLYLGLLTLVFTMYLIPGLWGAPLKLISAFPPPPQYSESPFGVGGSGNGAVSSESIKGLPEGAELGPHGIMVFHD
YEDGLAYAKEIKKPIMLDFTGYACVNCRKMENNVWSEPTILPILKNDVVLISLYVDDKRELPKEEQFVTKSADKIITVGD
KWTDFMISKYKTNTQPLYVITDLEGNNLNASKPTISYVSADEYLHWLKEGISNFK
>Mature_695_residues
MNFNQNHRAILSRSIWNKITAFLLLFFFTLAGNAQILEPVKWTSKIEKKGNNAVLIFDGTIEKDWHMYSQFTPDGGPLAL
EISFKNQKGNYELVGKAKEGKTRTAYNDVFGVDETFFEGKAHIEQEIKIINPNLKTVDVDFDFQVCKEVCINSSKKFSIA
VPSTFKIDEALPVVSEAKLDETKTAALAVDTIKKETAAAEDQTVKAENEAKEDIPAPAPARSLWSIFFIAFLSGFAALLT
PCVFPMIPMTVSFFTKQSKSRAKGIRNAIIYGLSIIAIYVILGLIVTKIFGADALNALSTDVWFNLIFFVILIIFATSFL
GAFEIMLPNSWANKADQQADKGGLIGILFMALALAIVSFSCTGPIVGTLLVEAASNGGIAPVVGMLGFSSALALPFMLFA
MFPGWLNSLPKSGGWLNTVKVVLGFLELALAFKFLSNADLVLQLHFLEREVFIAIWIAIFGALTLYLFGKITLPHDSPTH
HISVGRLYLGLLTLVFTMYLIPGLWGAPLKLISAFPPPPQYSESPFGVGGSGNGAVSSESIKGLPEGAELGPHGIMVFHD
YEDGLAYAKEIKKPIMLDFTGYACVNCRKMENNVWSEPTILPILKNDVVLISLYVDDKRELPKEEQFVTKSADKIITVGD
KWTDFMISKYKTNTQPLYVITDLEGNNLNASKPTISYVSADEYLHWLKEGISNFK

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=256, Percent_Identity=28.515625, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 76530; Mature: 76530

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFNQNHRAILSRSIWNKITAFLLLFFFTLAGNAQILEPVKWTSKIEKKGNNAVLIFDGT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHCCCCEEEEECCC
IEKDWHMYSQFTPDGGPLALEISFKNQKGNYELVGKAKEGKTRTAYNDVFGVDETFFEGK
CCCCHHHHHCCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCCCHHHHHCCCCHHHHCCH
AHIEQEIKIINPNLKTVDVDFDFQVCKEVCINSSKKFSIAVPSTFKIDEALPVVSEAKLD
HHHCCCEEEECCCCEEEEECCCHHHHHHHHCCCCCEEEEECCCCEECHHCCCCHHHCCCC
ETKTAALAVDTIKKETAAAEDQTVKAENEAKEDIPAPAPARSLWSIFFIAFLSGFAALLT
CHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
PCVFPMIPMTVSFFTKQSKSRAKGIRNAIIYGLSIIAIYVILGLIVTKIFGADALNALST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
DVWFNLIFFVILIIFATSFLGAFEIMLPNSWANKADQQADKGGLIGILFMALALAIVSFS
HHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHC
CTGPIVGTLLVEAASNGGIAPVVGMLGFSSALALPFMLFAMFPGWLNSLPKSGGWLNTVK
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
VVLGFLELALAFKFLSNADLVLQLHFLEREVFIAIWIAIFGALTLYLFGKITLPHDSPTH
HHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCC
HISVGRLYLGLLTLVFTMYLIPGLWGAPLKLISAFPPPPQYSESPFGVGGSGNGAVSSES
EEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHH
IKGLPEGAELGPHGIMVFHDYEDGLAYAKEIKKPIMLDFTGYACVNCRKMENNVWSEPTI
HCCCCCCCCCCCCEEEEEEECCHHHHHHHHCCCCEEEEECCCEEEEEEHHCCCCCCCCCE
LPILKNDVVLISLYVDDKRELPKEEQFVTKSADKIITVGDKWTDFMISKYKTNTQPLYVI
EEEECCCEEEEEEEECCCCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCCCCEEEE
TDLEGNNLNASKPTISYVSADEYLHWLKEGISNFK
EECCCCCCCCCCCEEEEECHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNFNQNHRAILSRSIWNKITAFLLLFFFTLAGNAQILEPVKWTSKIEKKGNNAVLIFDGT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHCCCCEEEEECCC
IEKDWHMYSQFTPDGGPLALEISFKNQKGNYELVGKAKEGKTRTAYNDVFGVDETFFEGK
CCCCHHHHHCCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCCCHHHHHCCCCHHHHCCH
AHIEQEIKIINPNLKTVDVDFDFQVCKEVCINSSKKFSIAVPSTFKIDEALPVVSEAKLD
HHHCCCEEEECCCCEEEEECCCHHHHHHHHCCCCCEEEEECCCCEECHHCCCCHHHCCCC
ETKTAALAVDTIKKETAAAEDQTVKAENEAKEDIPAPAPARSLWSIFFIAFLSGFAALLT
CHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
PCVFPMIPMTVSFFTKQSKSRAKGIRNAIIYGLSIIAIYVILGLIVTKIFGADALNALST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
DVWFNLIFFVILIIFATSFLGAFEIMLPNSWANKADQQADKGGLIGILFMALALAIVSFS
HHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHC
CTGPIVGTLLVEAASNGGIAPVVGMLGFSSALALPFMLFAMFPGWLNSLPKSGGWLNTVK
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
VVLGFLELALAFKFLSNADLVLQLHFLEREVFIAIWIAIFGALTLYLFGKITLPHDSPTH
HHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCC
HISVGRLYLGLLTLVFTMYLIPGLWGAPLKLISAFPPPPQYSESPFGVGGSGNGAVSSES
EEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHH
IKGLPEGAELGPHGIMVFHDYEDGLAYAKEIKKPIMLDFTGYACVNCRKMENNVWSEPTI
HCCCCCCCCCCCCEEEEEEECCHHHHHHHHCCCCEEEEECCCEEEEEEHHCCCCCCCCCE
LPILKNDVVLISLYVDDKRELPKEEQFVTKSADKIITVGDKWTDFMISKYKTNTQPLYVI
EEEECCCEEEEEEEECCCCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCCCCEEEE
TDLEGNNLNASKPTISYVSADEYLHWLKEGISNFK
EECCCCCCCCCCCEEEEECHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA