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The map label for this gene is pabB [H]

Identifier: 146299893

GI number: 146299893

Start: 2586400

End: 2587686

Strand: Direct

Name: pabB [H]

Synonym: Fjoh_2137

Alternate gene names: 146299893

Gene position: 2586400-2587686 (Clockwise)

Preceding gene: 146299890

Following gene: 146299894

Centisome position: 42.42

GC content: 33.64

Gene sequence:

>1287_bases
TTGAGAGTTTCTATTCATAAACATATTTCAAATCCTTTTGATTTTAAACAACAGCTATTAAGCTGGTCACAGCAGTTTCG
AGAGGTTGTTTTTCTGGAAGGCAATGGCTATCCTGAGCAATATTCAAGTTTTGACTGTATTCTTGCTGTTGATGCTTTTA
CATCAATTAAAACTGATTTTCATAATGCATTCGAAGATTTAAAACAATACCAGCAAACCACTAAGGACTGGTTGTTTGGC
TATTTGTCGTATGACTTAAAAAATGATATTGAAGATTTAAAATCCAACAATTTTGACGGATTAGAATTTCCGGATTTGTT
TTTCTTTCAGCCCAAAAAAGTATTTCTGCTTAAAGGAAATGAACTGGAAATACAATATCTGCTTTTTTGTAATGATGAAT
TTGAAGATGATTTTAATGAGATAGTCGAAAATCAAAAGTCAAAAGCTGAAAGTTCTGCGTCTATAAAAATTGAACAGCGT
ATTTCAAAAGATTTATACGTAGAAAAAGTAAACCAAATGCTTCATCATATTCATATTGGTGATATGTATGAAGCCAATTT
CTGTATGGAATTTTATGCTGAAAATGTTGTTATAGATCCTCAGGAAAAATTCAGAAAACTAAATGAAATTTCGCAGGCGC
CATTTTCGGTTTTCTTTAAAAATCATAAACATTTTCTGCTTTCGGCATCGCCGGAACGCTATTTAAAAAAAGTTGGAGAA
ACTATTATTTCCCAGCCCATAAAAGGAACTTCAAAAAGAGCTGCAGACCCTGTAGAAGATGAAAAATCAAAAGTCATGCT
GGCTTCAGATGAAAAAGAACGTGCAGAGAATATTATGATAACTGATTTGGTACGTAATGATCTTTCACATACAGCTCAAA
AAGGTTCTGTTGAGGTAAAAGAACTCTGCGGTATTTATTCATTTCTGCAGGTGCATCAAATGATTTCGACCGTTGTTTCA
AAATTAGACAAACAATATTCGGCTGTAGATGTTTTAAAATCTACTTTTCCAATGGGAAGCATGACTGGAGCACCAAAAAT
TTCGGTAATGAAAATCATCGAAAATCTGGAAGAAACTAAACGCGGACTTTACAGTGGTGCTGTAGGATATTTTACGCCGG
AAGGGGATTTTGATTTTAATGTGGTAATTAGAAGCATATTATACAATCAGGAAAAACAATATGTTTCGTTTTCGGTAGGA
AGCGCTATAACATCTAAGTCGATCCCTGAAAAAGAATATGAAGAATGTTTGCTGAAAGCCAGAGCAATGCACGAAGTTTT
GCGATAA

Upstream 100 bases:

>100_bases
TCAAAAACGATATACTAAAAAGCGTGCCAATAATTTTAAGATATTCTTTTTATTGAAGGATTTTTTTTGTTGTAATTTTG
AAGTTTAAAAAATATCATTT

Downstream 100 bases:

>100_bases
TTTTTTTCGCTGTTAATGTCACGAATTTGCACGAATTACTTTTTTTGCCACAGATTAAAAGATTTACACAGATTTTTTTA
ATCCTTTAATCTGCGACTAA

Product: anthranilate synthase component I/chorismate-binding protein

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MRVSIHKHISNPFDFKQQLLSWSQQFREVVFLEGNGYPEQYSSFDCILAVDAFTSIKTDFHNAFEDLKQYQQTTKDWLFG
YLSYDLKNDIEDLKSNNFDGLEFPDLFFFQPKKVFLLKGNELEIQYLLFCNDEFEDDFNEIVENQKSKAESSASIKIEQR
ISKDLYVEKVNQMLHHIHIGDMYEANFCMEFYAENVVIDPQEKFRKLNEISQAPFSVFFKNHKHFLLSASPERYLKKVGE
TIISQPIKGTSKRAADPVEDEKSKVMLASDEKERAENIMITDLVRNDLSHTAQKGSVEVKELCGIYSFLQVHQMISTVVS
KLDKQYSAVDVLKSTFPMGSMTGAPKISVMKIIENLEETKRGLYSGAVGYFTPEGDFDFNVVIRSILYNQEKQYVSFSVG
SAITSKSIPEKEYEECLLKARAMHEVLR

Sequences:

>Translated_428_residues
MRVSIHKHISNPFDFKQQLLSWSQQFREVVFLEGNGYPEQYSSFDCILAVDAFTSIKTDFHNAFEDLKQYQQTTKDWLFG
YLSYDLKNDIEDLKSNNFDGLEFPDLFFFQPKKVFLLKGNELEIQYLLFCNDEFEDDFNEIVENQKSKAESSASIKIEQR
ISKDLYVEKVNQMLHHIHIGDMYEANFCMEFYAENVVIDPQEKFRKLNEISQAPFSVFFKNHKHFLLSASPERYLKKVGE
TIISQPIKGTSKRAADPVEDEKSKVMLASDEKERAENIMITDLVRNDLSHTAQKGSVEVKELCGIYSFLQVHQMISTVVS
KLDKQYSAVDVLKSTFPMGSMTGAPKISVMKIIENLEETKRGLYSGAVGYFTPEGDFDFNVVIRSILYNQEKQYVSFSVG
SAITSKSIPEKEYEECLLKARAMHEVLR
>Mature_428_residues
MRVSIHKHISNPFDFKQQLLSWSQQFREVVFLEGNGYPEQYSSFDCILAVDAFTSIKTDFHNAFEDLKQYQQTTKDWLFG
YLSYDLKNDIEDLKSNNFDGLEFPDLFFFQPKKVFLLKGNELEIQYLLFCNDEFEDDFNEIVENQKSKAESSASIKIEQR
ISKDLYVEKVNQMLHHIHIGDMYEANFCMEFYAENVVIDPQEKFRKLNEISQAPFSVFFKNHKHFLLSASPERYLKKVGE
TIISQPIKGTSKRAADPVEDEKSKVMLASDEKERAENIMITDLVRNDLSHTAQKGSVEVKELCGIYSFLQVHQMISTVVS
KLDKQYSAVDVLKSTFPMGSMTGAPKISVMKIIENLEETKRGLYSGAVGYFTPEGDFDFNVVIRSILYNQEKQYVSFSVG
SAITSKSIPEKEYEECLLKARAMHEVLR

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=349, Percent_Identity=33.5243553008596, Blast_Score=198, Evalue=7e-52,
Organism=Escherichia coli, GI1787518, Length=401, Percent_Identity=27.930174563591, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786809, Length=220, Percent_Identity=26.8181818181818, Blast_Score=76, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6320935, Length=272, Percent_Identity=29.7794117647059, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6324361, Length=280, Percent_Identity=32.8571428571429, Blast_Score=123, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 49451; Mature: 49451

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVSIHKHISNPFDFKQQLLSWSQQFREVVFLEGNGYPEQYSSFDCILAVDAFTSIKTDF
CCEEEHHHHCCHHHHHHHHHHHHHHHHEEEEECCCCCCHHHCCCCEEEEEHHHHHHHHHH
HNAFEDLKQYQQTTKDWLFGYLSYDLKNDIEDLKSNNFDGLEFPDLFFFQPKKVFLLKGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCEEEEEECC
ELEIQYLLFCNDEFEDDFNEIVENQKSKAESSASIKIEQRISKDLYVEKVNQMLHHIHIG
CEEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCC
DMYEANFCMEFYAENVVIDPQEKFRKLNEISQAPFSVFFKNHKHFLLSASPERYLKKVGE
CCHHHHHHHHHHHCCCEECCHHHHHHHHHHHHCCHHHHHHCCCEEEEECCHHHHHHHHHH
TIISQPIKGTSKRAADPVEDEKSKVMLASDEKERAENIMITDLVRNDLSHTAQKGSVEVK
HHHHCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHCCHHHHHHHHHHHHHHHCCCCHHH
ELCGIYSFLQVHQMISTVVSKLDKQYSAVDVLKSTFPMGSMTGAPKISVMKIIENLEETK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
RGLYSGAVGYFTPEGDFDFNVVIRSILYNQEKQYVSFSVGSAITSKSIPEKEYEECLLKA
HHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHEEEEEHHHHHHHCCCCHHHHHHHHHHH
RAMHEVLR
HHHHHHHC
>Mature Secondary Structure
MRVSIHKHISNPFDFKQQLLSWSQQFREVVFLEGNGYPEQYSSFDCILAVDAFTSIKTDF
CCEEEHHHHCCHHHHHHHHHHHHHHHHEEEEECCCCCCHHHCCCCEEEEEHHHHHHHHHH
HNAFEDLKQYQQTTKDWLFGYLSYDLKNDIEDLKSNNFDGLEFPDLFFFQPKKVFLLKGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCEEEEEECC
ELEIQYLLFCNDEFEDDFNEIVENQKSKAESSASIKIEQRISKDLYVEKVNQMLHHIHIG
CEEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCC
DMYEANFCMEFYAENVVIDPQEKFRKLNEISQAPFSVFFKNHKHFLLSASPERYLKKVGE
CCHHHHHHHHHHHCCCEECCHHHHHHHHHHHHCCHHHHHHCCCEEEEECCHHHHHHHHHH
TIISQPIKGTSKRAADPVEDEKSKVMLASDEKERAENIMITDLVRNDLSHTAQKGSVEVK
HHHHCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHCCHHHHHHHHHHHHHHHCCCCHHH
ELCGIYSFLQVHQMISTVVSKLDKQYSAVDVLKSTFPMGSMTGAPKISVMKIIENLEETK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
RGLYSGAVGYFTPEGDFDFNVVIRSILYNQEKQYVSFSVGSAITSKSIPEKEYEECLLKA
HHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHEEEEEHHHHHHHCCCCHHHHHHHHHHH
RAMHEVLR
HHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]