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The map label for this gene is uxuA [H]

Identifier: 146299755

GI number: 146299755

Start: 2328556

End: 2329719

Strand: Direct

Name: uxuA [H]

Synonym: Fjoh_1995

Alternate gene names: 146299755

Gene position: 2328556-2329719 (Clockwise)

Preceding gene: 146299754

Following gene: 146299756

Centisome position: 38.19

GC content: 36.0

Gene sequence:

>1164_bases
ATGCAGCAAACCATGAGATGGTTCGGACCAAACGACAATGTCAAATTAATTGACATTCGGCAAGCTGGCGCAGCGGGAAT
TGTAACCGCATTGCATCAAATTCCGGTTGGCGATGTCTGGACAGTTGATGCAATAAAAGAAAGACAGGAAATTATTCGTA
ATTCCGGCTTGGAATGGACTGTGGTTGAAAGTCTTCCTGTTCATGAAGAAATTAAACGAGCTTCTGGAAATTATCTGCAA
TACATCGAGAATTATAAAATCAGTTTGCAAAATCTGGCAGAATGCGGTATCAAAATCATTACCTATAATTTTATGCCGAT
TTTGGATTGGGTTCGAACGAATCATAATTTTATCAATGAAGATGGAAGCAGAGCTTTGCTTTACAATCAGGATGCATTTA
CTTATTTTGATGTTTTTCTTTTAAAAAGACCAAATTCAGAAAACGATTATTCAGATGCTGAAAAAGAAAAAGCTTTGCAG
TTTGGGAATCAATTGTCTGAAGATGAAAAAGCACTTTTGTTTAAAAATGTTTTATTAGGACTGCCGGGAAGTAAAATCAA
TTTTACGGCCGAACAGATTTTGTCTCTTTTAGAAAATTATGCCGAAATCGACAATCAAAAACTAAGAGAAAATCTGATTT
ATTTTTTATCAGAAGTAACTCCGATTGCGGAGAAAAACCAACAAAAATTAGCGATTCATCCAGATGATCCGCCGTTTTCG
GTTTTAGGACTTCCGAGAATTGTTTCAACCGAAGCCGATTTAAAAGCTATTTTTAATGCCGTTCCTTCAACTGCCAATGG
TTTATGTTATTGTACAGGTTCGTTAAGTGCAGACCCAAAAAACAATCTTGAAAAAATTATAGCCGATTTTGGAGATAGAA
TTCACTTTTTACATCTTCGAAATACCATCCGCGAAAGCGAAACTATTTTTAGAGAATCAGAGCATTTAAACGGTGACGTT
AAAATGGAAATTATCGTTGAGAAATTATTGCTGTTGATGAACAAAACCCAAATAAGCCTGCCAATGCGTCCCGATCATGG
TTTCCTTCACAGAGTTGATGAAGCAATAGAAACCTATCCGGGTTATTCTTTGACAGGAAGACTAAAAGGGCTTGCTGAAT
TAAGAGGTTTAGAAATGGGAATTGCTTATAAACTGAATTTGTAA

Upstream 100 bases:

>100_bases
TGTGTTAGGAACTTGTTTCTTTTAAGTCTTTTTTCGAGTTAATATAAATCTATGTTTCTATGTGTTTAATTAATTTTTAC
AAAAGTTAAGTATGATAAAA

Downstream 100 bases:

>100_bases
TTTTTTTTCGTGTTAAACTGACTGGTTTTAAAAACCTGATAGTTCTGCGATGAGAAAAAAAAGTCCTGTTTATCATTTCG
AGAATAAAAAGTAAGTATTA

Product: mannonate dehydratase

Products: NA

Alternate protein names: D-mannonate hydrolase [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MQQTMRWFGPNDNVKLIDIRQAGAAGIVTALHQIPVGDVWTVDAIKERQEIIRNSGLEWTVVESLPVHEEIKRASGNYLQ
YIENYKISLQNLAECGIKIITYNFMPILDWVRTNHNFINEDGSRALLYNQDAFTYFDVFLLKRPNSENDYSDAEKEKALQ
FGNQLSEDEKALLFKNVLLGLPGSKINFTAEQILSLLENYAEIDNQKLRENLIYFLSEVTPIAEKNQQKLAIHPDDPPFS
VLGLPRIVSTEADLKAIFNAVPSTANGLCYCTGSLSADPKNNLEKIIADFGDRIHFLHLRNTIRESETIFRESEHLNGDV
KMEIIVEKLLLLMNKTQISLPMRPDHGFLHRVDEAIETYPGYSLTGRLKGLAELRGLEMGIAYKLNL

Sequences:

>Translated_387_residues
MQQTMRWFGPNDNVKLIDIRQAGAAGIVTALHQIPVGDVWTVDAIKERQEIIRNSGLEWTVVESLPVHEEIKRASGNYLQ
YIENYKISLQNLAECGIKIITYNFMPILDWVRTNHNFINEDGSRALLYNQDAFTYFDVFLLKRPNSENDYSDAEKEKALQ
FGNQLSEDEKALLFKNVLLGLPGSKINFTAEQILSLLENYAEIDNQKLRENLIYFLSEVTPIAEKNQQKLAIHPDDPPFS
VLGLPRIVSTEADLKAIFNAVPSTANGLCYCTGSLSADPKNNLEKIIADFGDRIHFLHLRNTIRESETIFRESEHLNGDV
KMEIIVEKLLLLMNKTQISLPMRPDHGFLHRVDEAIETYPGYSLTGRLKGLAELRGLEMGIAYKLNL
>Mature_387_residues
MQQTMRWFGPNDNVKLIDIRQAGAAGIVTALHQIPVGDVWTVDAIKERQEIIRNSGLEWTVVESLPVHEEIKRASGNYLQ
YIENYKISLQNLAECGIKIITYNFMPILDWVRTNHNFINEDGSRALLYNQDAFTYFDVFLLKRPNSENDYSDAEKEKALQ
FGNQLSEDEKALLFKNVLLGLPGSKINFTAEQILSLLENYAEIDNQKLRENLIYFLSEVTPIAEKNQQKLAIHPDDPPFS
VLGLPRIVSTEADLKAIFNAVPSTANGLCYCTGSLSADPKNNLEKIIADFGDRIHFLHLRNTIRESETIFRESEHLNGDV
KMEIIVEKLLLLMNKTQISLPMRPDHGFLHRVDEAIETYPGYSLTGRLKGLAELRGLEMGIAYKLNL

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1312

COG function: function code G; D-mannonate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannonate dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1790778, Length=387, Percent_Identity=48.3204134366925, Blast_Score=393, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004628
- InterPro:   IPR013022 [H]

Pfam domain/function: PF03786 UxuA [H]

EC number: =4.2.1.8 [H]

Molecular weight: Translated: 43995; Mature: 43995

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQTMRWFGPNDNVKLIDIRQAGAAGIVTALHQIPVGDVWTVDAIKERQEIIRNSGLEWT
CCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCEE
VVESLPVHEEIKRASGNYLQYIENYKISLQNLAECGIKIITYNFMPILDWVRTNHNFINE
EECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHCCCCCCCC
DGSRALLYNQDAFTYFDVFLLKRPNSENDYSDAEKEKALQFGNQLSEDEKALLFKNVLLG
CCCEEEEECCCCHHEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
LPGSKINFTAEQILSLLENYAEIDNQKLRENLIYFLSEVTPIAEKNQQKLAIHPDDPPFS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEECCCCCCCH
VLGLPRIVSTEADLKAIFNAVPSTANGLCYCTGSLSADPKNNLEKIIADFGDRIHFLHLR
HCCCCHHHCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCEEEEHHH
NTIRESETIFRESEHLNGDVKMEIIVEKLLLLMNKTQISLPMRPDHGFLHRVDEAIETYP
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHCC
GYSLTGRLKGLAELRGLEMGIAYKLNL
CCEEHHHHHHHHHHCCCEECEEEEECC
>Mature Secondary Structure
MQQTMRWFGPNDNVKLIDIRQAGAAGIVTALHQIPVGDVWTVDAIKERQEIIRNSGLEWT
CCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCEE
VVESLPVHEEIKRASGNYLQYIENYKISLQNLAECGIKIITYNFMPILDWVRTNHNFINE
EECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHCCCCCCCC
DGSRALLYNQDAFTYFDVFLLKRPNSENDYSDAEKEKALQFGNQLSEDEKALLFKNVLLG
CCCEEEEECCCCHHEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
LPGSKINFTAEQILSLLENYAEIDNQKLRENLIYFLSEVTPIAEKNQQKLAIHPDDPPFS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEECCCCCCCH
VLGLPRIVSTEADLKAIFNAVPSTANGLCYCTGSLSADPKNNLEKIIADFGDRIHFLHLR
HCCCCHHHCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCEEEEHHH
NTIRESETIFRESEHLNGDVKMEIIVEKLLLLMNKTQISLPMRPDHGFLHRVDEAIETYP
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHCC
GYSLTGRLKGLAELRGLEMGIAYKLNL
CCEEHHHHHHHHHHCCCEECEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]