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The map label for this gene is steT [H]

Identifier: 146299721

GI number: 146299721

Start: 2274818

End: 2276227

Strand: Direct

Name: steT [H]

Synonym: Fjoh_1961

Alternate gene names: 146299721

Gene position: 2274818-2276227 (Clockwise)

Preceding gene: 146299714

Following gene: 146299728

Centisome position: 37.31

GC content: 35.74

Gene sequence:

>1410_bases
ATGCAAGAAGAGAACCAAGAACATTTTAAAAGAGAACTCGGATTATTAGACGGAACCATGCTTGTGGTTGGTTCAATGAT
TGGGTCTGGAATATTTATTGTAAGTGCCGATATTGCCAGGCAGGTAGGATCTGCAGGATGGCTTACTCTAATTTGGCTGA
TATCAGGATTAATTACCATTATTGCTGCTGTAAGCTATGGAGAATTGAGCGCCATGTTTCCAAAAGCCGGAGGACAATAT
GTCTACTTAAAAGAAGCGTATAACAAGTTAATAGCTTTTTTGTATGGCTGGAGCTTTTTTGCAGTAATTCAAACTGGAAC
TATTGCTGCAGTGGGAGTAGCTTTCTCAAAATTTGCTGCTTATTTATACGAACCATTGAGTGATGAAAATATACTTTATG
AAATAGGTTCATTTAAACTAAATGCGGCCCAGTTAGTATCGATTTTTACTATTATTTTATTGACTTATATCAATAGCCGT
GGTGTTAAAAACGGTAAAATTCTTCAAACTGTTCTTACGATTATCAAAATTTTATCATTACTGGGGTTAATTGTTTTCGG
GCTAACATTGGCAGCAAAAGCTTCGGTTTGGGATGCGAACTGGGCCGATGCATGGAATACTCGTGTATTTGATAAAGAAA
GCGGCTCATGGATGCCAATAGGAGGGACTGGATTAATAACCGGAATTTCAGCTGCAATGGTTGGATCTTTATTTTCGAGT
GATGCCTGGAATGGTGTTACTTTTATTGCTGGAGAAATTAAAAATCCGCAGCGAAATGTTGGTTTAAGTTTGTTTCTGGG
AACTTTTATTGTAACCATTATTTATGTTTTAACGAATATTATGTATTTAGCCGTAATTCCGTTAGAAGAAATTGCAACAG
CAAAATCAGATCGTGTTGCCGTTGTGGCATCACAATATATTTTTGGAAATATAGGAACGCTGATTATTGCAATTATGATT
ATGATTTCGACTTTTGCCTGCAACAACGGATTAATTATGGCTGGAGCAAGAGTGTATTATACAATGGCAAAGGATGGTTT
ATTCTTTAAAAAAGCAGCTGTTTTAAACGAATCAAGTGTTCCTGCATGGGCGCTTTGGGCACAATGTTTTTGGGCTTCGG
CTTTGTGCCTTACAGGAAAATATGGTGATTTGTTAGACTTTGTAATTATCATTGTCTTGATTTTCTATATTTTAACGATA
TACGGAATCTTTATTTTGAGAAGAAAAATGCCAAATACCGAAAGACCTTATAAAGCTTTTGGATATCCGTTTTTACCAAT
GCTTTATATAATTACAGCTGCAGCAATATGTGTTTCGTTACTTATTACAAAATTCTCAACCTGTGGATGGGGAGTTTTAA
TTATGCTGACAGGAATTCCGGTTTATTATTTTACTAAACCAAAAGAGTAA

Upstream 100 bases:

>100_bases
GGGATACGCCCAGAATATTTTTCGATAATCTAAAAACTATGATCTAAAATCTAAATTTTCTAAAAAAAGTATATCTTTAA
CCAACCTAAAACCAAAAACA

Downstream 100 bases:

>100_bases
ACTTTTATTTGATCTGAAATTTTTAAGTTAAATTATAAAAAAGCGTCTTTATATAAAGGCGCTTTTTTAGTACAAACAAA
TTTATAATCGAGAATCTGCG

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MQEENQEHFKRELGLLDGTMLVVGSMIGSGIFIVSADIARQVGSAGWLTLIWLISGLITIIAAVSYGELSAMFPKAGGQY
VYLKEAYNKLIAFLYGWSFFAVIQTGTIAAVGVAFSKFAAYLYEPLSDENILYEIGSFKLNAAQLVSIFTIILLTYINSR
GVKNGKILQTVLTIIKILSLLGLIVFGLTLAAKASVWDANWADAWNTRVFDKESGSWMPIGGTGLITGISAAMVGSLFSS
DAWNGVTFIAGEIKNPQRNVGLSLFLGTFIVTIIYVLTNIMYLAVIPLEEIATAKSDRVAVVASQYIFGNIGTLIIAIMI
MISTFACNNGLIMAGARVYYTMAKDGLFFKKAAVLNESSVPAWALWAQCFWASALCLTGKYGDLLDFVIIIVLIFYILTI
YGIFILRRKMPNTERPYKAFGYPFLPMLYIITAAAICVSLLITKFSTCGWGVLIMLTGIPVYYFTKPKE

Sequences:

>Translated_469_residues
MQEENQEHFKRELGLLDGTMLVVGSMIGSGIFIVSADIARQVGSAGWLTLIWLISGLITIIAAVSYGELSAMFPKAGGQY
VYLKEAYNKLIAFLYGWSFFAVIQTGTIAAVGVAFSKFAAYLYEPLSDENILYEIGSFKLNAAQLVSIFTIILLTYINSR
GVKNGKILQTVLTIIKILSLLGLIVFGLTLAAKASVWDANWADAWNTRVFDKESGSWMPIGGTGLITGISAAMVGSLFSS
DAWNGVTFIAGEIKNPQRNVGLSLFLGTFIVTIIYVLTNIMYLAVIPLEEIATAKSDRVAVVASQYIFGNIGTLIIAIMI
MISTFACNNGLIMAGARVYYTMAKDGLFFKKAAVLNESSVPAWALWAQCFWASALCLTGKYGDLLDFVIIIVLIFYILTI
YGIFILRRKMPNTERPYKAFGYPFLPMLYIITAAAICVSLLITKFSTCGWGVLIMLTGIPVYYFTKPKE
>Mature_469_residues
MQEENQEHFKRELGLLDGTMLVVGSMIGSGIFIVSADIARQVGSAGWLTLIWLISGLITIIAAVSYGELSAMFPKAGGQY
VYLKEAYNKLIAFLYGWSFFAVIQTGTIAAVGVAFSKFAAYLYEPLSDENILYEIGSFKLNAAQLVSIFTIILLTYINSR
GVKNGKILQTVLTIIKILSLLGLIVFGLTLAAKASVWDANWADAWNTRVFDKESGSWMPIGGTGLITGISAAMVGSLFSS
DAWNGVTFIAGEIKNPQRNVGLSLFLGTFIVTIIYVLTNIMYLAVIPLEEIATAKSDRVAVVASQYIFGNIGTLIIAIMI
MISTFACNNGLIMAGARVYYTMAKDGLFFKKAAVLNESSVPAWALWAQCFWASALCLTGKYGDLLDFVIIIVLIFYILTI
YGIFILRRKMPNTERPYKAFGYPFLPMLYIITAAAICVSLLITKFSTCGWGVLIMLTGIPVYYFTKPKE

Specific function: Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family [H]

Homologues:

Organism=Homo sapiens, GI115648063, Length=457, Percent_Identity=29.3216630196937, Blast_Score=182, Evalue=7e-46,
Organism=Homo sapiens, GI115648022, Length=457, Percent_Identity=29.3216630196937, Blast_Score=182, Evalue=7e-46,
Organism=Homo sapiens, GI186910308, Length=461, Percent_Identity=29.7180043383948, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI186910306, Length=461, Percent_Identity=29.7180043383948, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI186910304, Length=461, Percent_Identity=29.7180043383948, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI33286428, Length=465, Percent_Identity=28.1720430107527, Blast_Score=172, Evalue=9e-43,
Organism=Homo sapiens, GI187423910, Length=474, Percent_Identity=27.4261603375527, Blast_Score=166, Evalue=6e-41,
Organism=Homo sapiens, GI7657591, Length=474, Percent_Identity=27.4261603375527, Blast_Score=166, Evalue=6e-41,
Organism=Homo sapiens, GI7657683, Length=465, Percent_Identity=29.6774193548387, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI71979932, Length=472, Percent_Identity=29.2372881355932, Blast_Score=155, Evalue=9e-38,
Organism=Homo sapiens, GI9790235, Length=465, Percent_Identity=26.8817204301075, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI33286430, Length=246, Percent_Identity=28.0487804878049, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI71999149, Length=426, Percent_Identity=25.3521126760563, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI4507047, Length=431, Percent_Identity=23.8979118329466, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI258614003, Length=427, Percent_Identity=25.0585480093677, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI258614005, Length=429, Percent_Identity=24.9417249417249, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI258645169, Length=426, Percent_Identity=23.7089201877934, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI110347453, Length=364, Percent_Identity=24.1758241758242, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI181337167, Length=416, Percent_Identity=22.3557692307692, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI114326544, Length=422, Percent_Identity=22.7488151658768, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI114326550, Length=422, Percent_Identity=22.7488151658768, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87082250, Length=471, Percent_Identity=26.7515923566879, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI2367353, Length=433, Percent_Identity=22.1709006928406, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788480, Length=476, Percent_Identity=23.7394957983193, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790584, Length=341, Percent_Identity=26.3929618768328, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1790653, Length=394, Percent_Identity=22.5888324873096, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87081708, Length=504, Percent_Identity=23.2142857142857, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1787890, Length=425, Percent_Identity=24.7058823529412, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786302, Length=460, Percent_Identity=20.8695652173913, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17540018, Length=476, Percent_Identity=29.4117647058824, Blast_Score=179, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17568033, Length=477, Percent_Identity=28.0922431865828, Blast_Score=154, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI32566699, Length=483, Percent_Identity=26.5010351966874, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71982612, Length=465, Percent_Identity=27.5268817204301, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI71982608, Length=465, Percent_Identity=27.5268817204301, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17532491, Length=410, Percent_Identity=26.5853658536585, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71982623, Length=298, Percent_Identity=30.5369127516779, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI71995382, Length=468, Percent_Identity=26.2820512820513, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71995388, Length=468, Percent_Identity=26.2820512820513, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI193208714, Length=447, Percent_Identity=24.8322147651007, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI32566695, Length=447, Percent_Identity=24.8322147651007, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17533459, Length=415, Percent_Identity=25.3012048192771, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71990446, Length=459, Percent_Identity=23.9651416122004, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17531343, Length=414, Percent_Identity=24.8792270531401, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71993915, Length=468, Percent_Identity=25.6410256410256, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6321751, Length=343, Percent_Identity=26.530612244898, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6321492, Length=388, Percent_Identity=23.7113402061856, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357367, Length=478, Percent_Identity=32.2175732217573, Blast_Score=194, Evalue=8e-50,
Organism=Drosophila melanogaster, GI221331183, Length=468, Percent_Identity=30.5555555555556, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI17647653, Length=468, Percent_Identity=30.5555555555556, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI24664379, Length=468, Percent_Identity=30.5555555555556, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI45550968, Length=463, Percent_Identity=28.2937365010799, Blast_Score=175, Evalue=5e-44,
Organism=Drosophila melanogaster, GI19921172, Length=463, Percent_Identity=28.2937365010799, Blast_Score=175, Evalue=5e-44,
Organism=Drosophila melanogaster, GI24641993, Length=417, Percent_Identity=28.7769784172662, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24641995, Length=417, Percent_Identity=28.7769784172662, Blast_Score=172, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24651635, Length=459, Percent_Identity=26.5795206971678, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24651633, Length=459, Percent_Identity=26.5795206971678, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24667468, Length=431, Percent_Identity=26.2180974477958, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24668806, Length=421, Percent_Identity=23.9904988123515, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21356285, Length=421, Percent_Identity=23.9904988123515, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24668802, Length=421, Percent_Identity=23.9904988123515, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI221512776, Length=362, Percent_Identity=21.8232044198895, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24666159, Length=362, Percent_Identity=21.8232044198895, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI161077963, Length=414, Percent_Identity=20.7729468599034, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281366235, Length=360, Percent_Identity=23.8888888888889, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI116007820, Length=360, Percent_Identity=23.8888888888889, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51355; Mature: 51355

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEENQEHFKRELGLLDGTMLVVGSMIGSGIFIVSADIARQVGSAGWLTLIWLISGLITI
CCCCCHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEHHHHHHHCCCHHHHHHHHHHHHHHH
IAAVSYGELSAMFPKAGGQYVYLKEAYNKLIAFLYGWSFFAVIQTGTIAAVGVAFSKFAA
HHHHCCCHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
YLYEPLSDENILYEIGSFKLNAAQLVSIFTIILLTYINSRGVKNGKILQTVLTIIKILSL
HHHCCCCCCCEEEEECCCEECHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LGLIVFGLTLAAKASVWDANWADAWNTRVFDKESGSWMPIGGTGLITGISAAMVGSLFSS
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCEEECCCCHHHHHHHHHHHHHHHCC
DAWNGVTFIAGEIKNPQRNVGLSLFLGTFIVTIIYVLTNIMYLAVIPLEEIATAKSDRVA
CCCCCEEEEEECCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCEE
VVASQYIFGNIGTLIIAIMIMISTFACNNGLIMAGARVYYTMAKDGLFFKKAAVLNESSV
EEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEECCCCCHHHHHHHHCCCCC
PAWALWAQCFWASALCLTGKYGDLLDFVIIIVLIFYILTIYGIFILRRKMPNTERPYKAF
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHC
GYPFLPMLYIITAAAICVSLLITKFSTCGWGVLIMLTGIPVYYFTKPKE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEECCCC
>Mature Secondary Structure
MQEENQEHFKRELGLLDGTMLVVGSMIGSGIFIVSADIARQVGSAGWLTLIWLISGLITI
CCCCCHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEHHHHHHHCCCHHHHHHHHHHHHHHH
IAAVSYGELSAMFPKAGGQYVYLKEAYNKLIAFLYGWSFFAVIQTGTIAAVGVAFSKFAA
HHHHCCCHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
YLYEPLSDENILYEIGSFKLNAAQLVSIFTIILLTYINSRGVKNGKILQTVLTIIKILSL
HHHCCCCCCCEEEEECCCEECHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LGLIVFGLTLAAKASVWDANWADAWNTRVFDKESGSWMPIGGTGLITGISAAMVGSLFSS
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCEEECCCCHHHHHHHHHHHHHHHCC
DAWNGVTFIAGEIKNPQRNVGLSLFLGTFIVTIIYVLTNIMYLAVIPLEEIATAKSDRVA
CCCCCEEEEEECCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCEE
VVASQYIFGNIGTLIIAIMIMISTFACNNGLIMAGARVYYTMAKDGLFFKKAAVLNESSV
EEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEECCCCCHHHHHHHHCCCCC
PAWALWAQCFWASALCLTGKYGDLLDFVIIIVLIFYILTIYGIFILRRKMPNTERPYKAF
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHC
GYPFLPMLYIITAAAICVSLLITKFSTCGWGVLIMLTGIPVYYFTKPKE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]