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The map label for this gene is spoVD [H]

Identifier: 146299565

GI number: 146299565

Start: 2084832

End: 2086841

Strand: Direct

Name: spoVD [H]

Synonym: Fjoh_1805

Alternate gene names: 146299565

Gene position: 2084832-2086841 (Clockwise)

Preceding gene: 146299564

Following gene: 146299566

Centisome position: 34.2

GC content: 35.82

Gene sequence:

>2010_bases
ATGGCAGTAGACGATAAACATATATCCTACAGAATTTACCTCGTAGCAGTTTTCATCTTTTTGATGGCAATTGCTATTGT
CGTTAAATTAACCAATATTCAATGGGTTGAAGGAGATTATTACAGAAAACTGGCGAAACAGCGTACAGTAAGAAATTTTG
TAATTCCGGCAAATAAAGGAAATATTTATTCTGCCGACGGAAGTTTACTGGCAACATCAATTCCAAATTATGAAATTCGT
TTTGATGCAAAAGCGCCAAAAACAGAAACTTTTGAGAAATATGTAAAACAATTGTCAGATTCTCTGGAAACTGTTTTAGA
CAGACCATCAGGTTATTACGAAAAAGAATTAAGAAAAGCGAGAGCCAATAAAAACCGTTATTATTTAATTGCCCGCAACC
TAAGTTATACCGAATATGTGAAAATTAAAGGATTTCCATTATTCAATTTAGGTGCTTTTAAAGGCGGAATTATCGTAGAG
CAGGAAACCGTTAGAAAACATCCGATAGGTAAAATTGCCGAAAGAACAATTGGTTATGACCGAATTGACCCGGCAACCGG
AGTTGAAGTTGGAAAAGGAATCGAATGGGCTTTTAAAAACTATCTAAACGGAAAAGACGGAAAAATTCTAAAACAAAAAA
TTGCAAAAGGACAGTGGAAACCGATTCGTGATGTAAACGAAGTAGATCCAATTGACGGCTACGATGTAATTTCGACTATA
GATGTTTTTATTCAGGATATTGCACATCACGCTTTATTAAAACAATTAGAAGATTACGAAGCAGATCACGGTTGTGTTGT
GGTTATGGAAACACAAACAGGTCATGTAAAAGCAATTTCAAATTTAGGAAGAGCAGAAGACGGATCGTATTACGAAACAA
CAAATTATGCTATTGCTGAATCTCAGGAACCCGGATCGACTTTTAAACTAGTTGATTTAATGGCGATTTTAGAAGATAAA
GTGGCAGATACAAGTAAGGTTTATGATAGTCAGGGTGGTGTAGTTAAATATTATGGAAAATCAGTCCGCGATTCGCATCA
TGGCGGTTATGGAAAAGTTTCATTAGCCCGCGGATTTGAGCTTTCGTCAAACACCGTAATGGTTCAGGCTGTTTATGAAA
ATTACAAAAATAATCCATCGAAGTTTGTAAATCATATCAAAAGCTGGGGATTAAATAAAACTTTGGGCTTGCATTTTAAA
GGAGAAGGAAGACCTTATATTCCGCAGCCGGGAGACAAACATTGGTCAGGAACTACACTTCCGTGGATGGCTTTTGGATA
TAATGTTTCGGTTACACCAATGCAGACACTGGCATTTTACAATTCAGTTGCAAATGATGGTGTAATGGTTAAACCGCAGT
TTGTATCTGAAATTAAAGAATGGAATAAAACGATTAAAAAGTTTGATGTCGAAGTAATAAACCCAAGAGTCTGCTCGCCT
GAGACTTTGAAGAAAGTAAGAGCGGTTTTGCAAAATGTGGTTAAAAAAGGAACGGGTTCTAAACTGTATTCGAAAGATTT
TTCAATGGCAGGAAAAACAGGAACAGCTCAGGTTAATTACGGCGGGAAAGAAGGAAAATCAGCATTGTATTATGCGTCTT
CTTTCGTTGGATATTTTCCGGCAGATCATCCAAAATATTCTTGTATTGTAGTGGTTCACAAACCCAATACTGCTAGAAAT
AATTATTATGGAGCAGACGTTGCAGGACCGGTTTTTAAAAGAATCGCTCAAAAAATATTTACAGATGCGCCATCAACCAA
TAAAATAAAACAACTGGATTCTAAGATTGCAAAACAGGAAGTCAGTTATGAAAAATATGAAAAGGAGGCTAATAAAAAAT
TAAGCCAGATTCCTGATTTAAAAGGAATGCCGGGAATGGATGCGATTGCTTTGCTGGAAAATTTAGGTTTGAAAGTAAAA
GTAAATGGAATGGGGAAAGTAAAAAATCAATCGATTCAAGCTGGAACCAGTATTAGCAAAAACACAACAATTGTATTAGA
ATTATCGTGA

Upstream 100 bases:

>100_bases
TATCAGATAAAATGCTCGAAAAGCAGATTTTTCCATCAACGGTGCCTCCTGTAAAAATAGAAGTTAAAAAAGAAGAAGAA
AAAAGTTTCTTTAAAAGAAT

Downstream 100 bases:

>100_bases
AAGTATTAAAAGACATATTATATAAAGTAACTATTGAATCTGTAACAGGTTCAACAGATATTGATATTCAGAAAATCGAA
TTTGATTCACGCAAAGTAGA

Product: peptidoglycan glycosyltransferase

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 669; Mature: 668

Protein sequence:

>669_residues
MAVDDKHISYRIYLVAVFIFLMAIAIVVKLTNIQWVEGDYYRKLAKQRTVRNFVIPANKGNIYSADGSLLATSIPNYEIR
FDAKAPKTETFEKYVKQLSDSLETVLDRPSGYYEKELRKARANKNRYYLIARNLSYTEYVKIKGFPLFNLGAFKGGIIVE
QETVRKHPIGKIAERTIGYDRIDPATGVEVGKGIEWAFKNYLNGKDGKILKQKIAKGQWKPIRDVNEVDPIDGYDVISTI
DVFIQDIAHHALLKQLEDYEADHGCVVVMETQTGHVKAISNLGRAEDGSYYETTNYAIAESQEPGSTFKLVDLMAILEDK
VADTSKVYDSQGGVVKYYGKSVRDSHHGGYGKVSLARGFELSSNTVMVQAVYENYKNNPSKFVNHIKSWGLNKTLGLHFK
GEGRPYIPQPGDKHWSGTTLPWMAFGYNVSVTPMQTLAFYNSVANDGVMVKPQFVSEIKEWNKTIKKFDVEVINPRVCSP
ETLKKVRAVLQNVVKKGTGSKLYSKDFSMAGKTGTAQVNYGGKEGKSALYYASSFVGYFPADHPKYSCIVVVHKPNTARN
NYYGADVAGPVFKRIAQKIFTDAPSTNKIKQLDSKIAKQEVSYEKYEKEANKKLSQIPDLKGMPGMDAIALLENLGLKVK
VNGMGKVKNQSIQAGTSISKNTTIVLELS

Sequences:

>Translated_669_residues
MAVDDKHISYRIYLVAVFIFLMAIAIVVKLTNIQWVEGDYYRKLAKQRTVRNFVIPANKGNIYSADGSLLATSIPNYEIR
FDAKAPKTETFEKYVKQLSDSLETVLDRPSGYYEKELRKARANKNRYYLIARNLSYTEYVKIKGFPLFNLGAFKGGIIVE
QETVRKHPIGKIAERTIGYDRIDPATGVEVGKGIEWAFKNYLNGKDGKILKQKIAKGQWKPIRDVNEVDPIDGYDVISTI
DVFIQDIAHHALLKQLEDYEADHGCVVVMETQTGHVKAISNLGRAEDGSYYETTNYAIAESQEPGSTFKLVDLMAILEDK
VADTSKVYDSQGGVVKYYGKSVRDSHHGGYGKVSLARGFELSSNTVMVQAVYENYKNNPSKFVNHIKSWGLNKTLGLHFK
GEGRPYIPQPGDKHWSGTTLPWMAFGYNVSVTPMQTLAFYNSVANDGVMVKPQFVSEIKEWNKTIKKFDVEVINPRVCSP
ETLKKVRAVLQNVVKKGTGSKLYSKDFSMAGKTGTAQVNYGGKEGKSALYYASSFVGYFPADHPKYSCIVVVHKPNTARN
NYYGADVAGPVFKRIAQKIFTDAPSTNKIKQLDSKIAKQEVSYEKYEKEANKKLSQIPDLKGMPGMDAIALLENLGLKVK
VNGMGKVKNQSIQAGTSISKNTTIVLELS
>Mature_668_residues
AVDDKHISYRIYLVAVFIFLMAIAIVVKLTNIQWVEGDYYRKLAKQRTVRNFVIPANKGNIYSADGSLLATSIPNYEIRF
DAKAPKTETFEKYVKQLSDSLETVLDRPSGYYEKELRKARANKNRYYLIARNLSYTEYVKIKGFPLFNLGAFKGGIIVEQ
ETVRKHPIGKIAERTIGYDRIDPATGVEVGKGIEWAFKNYLNGKDGKILKQKIAKGQWKPIRDVNEVDPIDGYDVISTID
VFIQDIAHHALLKQLEDYEADHGCVVVMETQTGHVKAISNLGRAEDGSYYETTNYAIAESQEPGSTFKLVDLMAILEDKV
ADTSKVYDSQGGVVKYYGKSVRDSHHGGYGKVSLARGFELSSNTVMVQAVYENYKNNPSKFVNHIKSWGLNKTLGLHFKG
EGRPYIPQPGDKHWSGTTLPWMAFGYNVSVTPMQTLAFYNSVANDGVMVKPQFVSEIKEWNKTIKKFDVEVINPRVCSPE
TLKKVRAVLQNVVKKGTGSKLYSKDFSMAGKTGTAQVNYGGKEGKSALYYASSFVGYFPADHPKYSCIVVVHKPNTARNN
YYGADVAGPVFKRIAQKIFTDAPSTNKIKQLDSKIAKQEVSYEKYEKEANKKLSQIPDLKGMPGMDAIALLENLGLKVKV
NGMGKVKNQSIQAGTSISKNTTIVLELS

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=585, Percent_Identity=25.982905982906, Blast_Score=145, Evalue=9e-36,
Organism=Escherichia coli, GI1786854, Length=635, Percent_Identity=22.8346456692913, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 74752; Mature: 74621

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVDDKHISYRIYLVAVFIFLMAIAIVVKLTNIQWVEGDYYRKLAKQRTVRNFVIPANKG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHEEEECCCC
NIYSADGSLLATSIPNYEIRFDAKAPKTETFEKYVKQLSDSLETVLDRPSGYYEKELRKA
CEEECCCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RANKNRYYLIARNLSYTEYVKIKGFPLFNLGAFKGGIIVEQETVRKHPIGKIAERTIGYD
HCCCCEEEEEEECCCCEEEEEEECCCEEECCCCCCCEEEEHHHHHHCCCHHHHHHHCCCC
RIDPATGVEVGKGIEWAFKNYLNGKDGKILKQKIAKGQWKPIRDVNEVDPIDGYDVISTI
CCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHH
DVFIQDIAHHALLKQLEDYEADHGCVVVMETQTGHVKAISNLGRAEDGSYYETTNYAIAE
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHCCCCCCCCEEEECCEEEEC
SQEPGSTFKLVDLMAILEDKVADTSKVYDSQGGVVKYYGKSVRDSHHGGYGKVSLARGFE
CCCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEECCCHHCCCCCCCCCEEEEECCEE
LSSNTVMVQAVYENYKNNPSKFVNHIKSWGLNKTLGLHFKGEGRPYIPQPGDKHWSGTTL
ECCCCEEEEEEHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCC
PWMAFGYNVSVTPMQTLAFYNSVANDGVMVKPQFVSEIKEWNKTIKKFDVEVINPRVCSP
CCEEECCCEECCHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHCCEEECCCCCCH
ETLKKVRAVLQNVVKKGTGSKLYSKDFSMAGKTGTAQVNYGGKEGKSALYYASSFVGYFP
HHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCCEEEEHHHHHHCCC
ADHPKYSCIVVVHKPNTARNNYYGADVAGPVFKRIAQKIFTDAPSTNKIKQLDSKIAKQE
CCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VSYEKYEKEANKKLSQIPDLKGMPGMDAIALLENLGLKVKVNGMGKVKNQSIQAGTSISK
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCC
NTTIVLELS
CEEEEEEEC
>Mature Secondary Structure 
AVDDKHISYRIYLVAVFIFLMAIAIVVKLTNIQWVEGDYYRKLAKQRTVRNFVIPANKG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHEEEECCCC
NIYSADGSLLATSIPNYEIRFDAKAPKTETFEKYVKQLSDSLETVLDRPSGYYEKELRKA
CEEECCCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RANKNRYYLIARNLSYTEYVKIKGFPLFNLGAFKGGIIVEQETVRKHPIGKIAERTIGYD
HCCCCEEEEEEECCCCEEEEEEECCCEEECCCCCCCEEEEHHHHHHCCCHHHHHHHCCCC
RIDPATGVEVGKGIEWAFKNYLNGKDGKILKQKIAKGQWKPIRDVNEVDPIDGYDVISTI
CCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHH
DVFIQDIAHHALLKQLEDYEADHGCVVVMETQTGHVKAISNLGRAEDGSYYETTNYAIAE
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHCCCCCCCCEEEECCEEEEC
SQEPGSTFKLVDLMAILEDKVADTSKVYDSQGGVVKYYGKSVRDSHHGGYGKVSLARGFE
CCCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEECCCHHCCCCCCCCCEEEEECCEE
LSSNTVMVQAVYENYKNNPSKFVNHIKSWGLNKTLGLHFKGEGRPYIPQPGDKHWSGTTL
ECCCCEEEEEEHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCC
PWMAFGYNVSVTPMQTLAFYNSVANDGVMVKPQFVSEIKEWNKTIKKFDVEVINPRVCSP
CCEEECCCEECCHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHCCEEECCCCCCH
ETLKKVRAVLQNVVKKGTGSKLYSKDFSMAGKTGTAQVNYGGKEGKSALYYASSFVGYFP
HHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCCEEEEHHHHHHCCC
ADHPKYSCIVVVHKPNTARNNYYGADVAGPVFKRIAQKIFTDAPSTNKIKQLDSKIAKQE
CCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VSYEKYEKEANKKLSQIPDLKGMPGMDAIALLENLGLKVKVNGMGKVKNQSIQAGTSISK
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCC
NTTIVLELS
CEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]