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The map label for this gene is macB [H]

Identifier: 146299428

GI number: 146299428

Start: 1936324

End: 1937568

Strand: Direct

Name: macB [H]

Synonym: Fjoh_1668

Alternate gene names: 146299428

Gene position: 1936324-1937568 (Clockwise)

Preceding gene: 146299427

Following gene: 146299429

Centisome position: 31.76

GC content: 35.82

Gene sequence:

>1245_bases
ATGTTTAATATTGAGCGCTGGCAGGAAATATTTGAAGCCATTTCTAAAAACCGACTGCGAACATTTCTAACAGGAATTTC
GGTAGCATCGGGGATTTTTATTTTGGTGATTTTGCTTGGAGCCGGAAAAGGGCTTCAAAATGGCATTGAAAAACAATTTG
AAAGAGATGCTGCCGGAATTATCGAAGTCTGGTCTGGTACAACTACAAAAGAATATAAAGGATTGAATCCAGGAAGACAG
GTTCAGTTTCGAAATAGTGATTACAATCAATCTACTCAAAAATTTGAAGATAAATTAGATTTAAGAGCGTCAACACAAAA
TTATTGGGGGCAATCTTTTTCTTATGGAAAAGAATCAGGAAGTTATCAGTTTAGAGGTGTAGATCCTGATTATGGCGGCA
TCGAAAACCTAACAATAGTTCAGGGGCGTTATGTAAATAGTAAAGATTTGCAGAACAACGAAAAGGTTGCGGTTATTGGA
ATGAAATTAAAGAATGATTTGCTTAAGGATAAAGATGCGATAGGCGAAGAAATCTTAATTAACAATATCAGTTTTAAAGT
CATCGGTGTTTTTACAGATCCGGGAGGAGAAAGAGAAGAAACCAGAGCGTACCTGCCTTTAACAACAGTGCAGAGAACTT
TTGGAGGCGGAGATAAAATCAGCAATTTGTTTTTTACTTTAAAAAAGACAAGCAATTATGATGAAGCTTTGGCACAATCA
GAAAAATTTACACAGGATTTAAAAGATTTATTAAAGAGCAAAAATATGGTTGCTCCTGATGATGATGGCGGAGTAGGAGT
TTATAATTCTGTTAAAGATGCAAAGCAGTTTTATGATTTAAATCTTTACATCAGGTTATTTTTCTGGTGGGTTGGTATTT
GTACCATTATTGCCGGAGTTGTAGGTGTAAGTAACATCATGCTGATTATTGTAAAAGAAAGAACAAAAGAAATTGGAATT
CGTAAAGCTTTAGGAGCTTCTCCGTTTTCGATTATAGCCATGATACTTCACGAATCAATTTTTATTACCACTATTGCAGG
ATTTGTCGGGCTTTTGGCAAGTCTGCTGTTATTAGAATTTGTTGGACCGATGGTTCAGAGTGAATATTTTAGAAATCCAG
AAGTAGATTTCAGCGTGGCATTAACAACACTATTTTTACTTGTGTTTGCAGGTGCTCTGGCGGGATTTTTCCCAGCATAC
AGAGCAGCCAAAATTAAACCTATTGTAGCACTTAGAGACGAATAA

Upstream 100 bases:

>100_bases
CACGAACCAGATATTGCCGCAATGTGCAAAAGAAATGTGGTCCTGAAAGACGGATTAATTATCGATGATAAATTAGTAGA
ACAAGTTAGAGCTTCATCTT

Downstream 100 bases:

>100_bases
TTATGTTTAAAAAAGATAATTGGGACGAGATTTTACAGGCCTTAACGGCTAACCCATTCAGAACTATTCTGACGGCTTTT
GGTGTTTTTTGGGGAATTTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MFNIERWQEIFEAISKNRLRTFLTGISVASGIFILVILLGAGKGLQNGIEKQFERDAAGIIEVWSGTTTKEYKGLNPGRQ
VQFRNSDYNQSTQKFEDKLDLRASTQNYWGQSFSYGKESGSYQFRGVDPDYGGIENLTIVQGRYVNSKDLQNNEKVAVIG
MKLKNDLLKDKDAIGEEILINNISFKVIGVFTDPGGEREETRAYLPLTTVQRTFGGGDKISNLFFTLKKTSNYDEALAQS
EKFTQDLKDLLKSKNMVAPDDDGGVGVYNSVKDAKQFYDLNLYIRLFFWWVGICTIIAGVVGVSNIMLIIVKERTKEIGI
RKALGASPFSIIAMILHESIFITTIAGFVGLLASLLLLEFVGPMVQSEYFRNPEVDFSVALTTLFLLVFAGALAGFFPAY
RAAKIKPIVALRDE

Sequences:

>Translated_414_residues
MFNIERWQEIFEAISKNRLRTFLTGISVASGIFILVILLGAGKGLQNGIEKQFERDAAGIIEVWSGTTTKEYKGLNPGRQ
VQFRNSDYNQSTQKFEDKLDLRASTQNYWGQSFSYGKESGSYQFRGVDPDYGGIENLTIVQGRYVNSKDLQNNEKVAVIG
MKLKNDLLKDKDAIGEEILINNISFKVIGVFTDPGGEREETRAYLPLTTVQRTFGGGDKISNLFFTLKKTSNYDEALAQS
EKFTQDLKDLLKSKNMVAPDDDGGVGVYNSVKDAKQFYDLNLYIRLFFWWVGICTIIAGVVGVSNIMLIIVKERTKEIGI
RKALGASPFSIIAMILHESIFITTIAGFVGLLASLLLLEFVGPMVQSEYFRNPEVDFSVALTTLFLLVFAGALAGFFPAY
RAAKIKPIVALRDE
>Mature_414_residues
MFNIERWQEIFEAISKNRLRTFLTGISVASGIFILVILLGAGKGLQNGIEKQFERDAAGIIEVWSGTTTKEYKGLNPGRQ
VQFRNSDYNQSTQKFEDKLDLRASTQNYWGQSFSYGKESGSYQFRGVDPDYGGIENLTIVQGRYVNSKDLQNNEKVAVIG
MKLKNDLLKDKDAIGEEILINNISFKVIGVFTDPGGEREETRAYLPLTTVQRTFGGGDKISNLFFTLKKTSNYDEALAQS
EKFTQDLKDLLKSKNMVAPDDDGGVGVYNSVKDAKQFYDLNLYIRLFFWWVGICTIIAGVVGVSNIMLIIVKERTKEIGI
RKALGASPFSIIAMILHESIFITTIAGFVGLLASLLLLEFVGPMVQSEYFRNPEVDFSVALTTLFLLVFAGALAGFFPAY
RAAKIKPIVALRDE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=410, Percent_Identity=26.0975609756098, Blast_Score=111, Evalue=9e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46194; Mature: 46194

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNIERWQEIFEAISKNRLRTFLTGISVASGIFILVILLGAGKGLQNGIEKQFERDAAGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
IEVWSGTTTKEYKGLNPGRQVQFRNSDYNQSTQKFEDKLDLRASTQNYWGQSFSYGKESG
EEECCCCCHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCC
SYQFRGVDPDYGGIENLTIVQGRYVNSKDLQNNEKVAVIGMKLKNDLLKDKDAIGEEILI
CEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHCCCHHEE
NNISFKVIGVFTDPGGEREETRAYLPLTTVQRTFGGGDKISNLFFTLKKTSNYDEALAQS
ECCCEEEEEEEECCCCCHHHCEEECCHHHHHHHCCCCHHHHHHHEEEECCCCHHHHHHHH
EKFTQDLKDLLKSKNMVAPDDDGGVGVYNSVKDAKQFYDLNLYIRLFFWWVGICTIIAGV
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGVSNIMLIIVKERTKEIGIRKALGASPFSIIAMILHESIFITTIAGFVGLLASLLLLEF
HHHCCEEEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGPMVQSEYFRNPEVDFSVALTTLFLLVFAGALAGFFPAYRAAKIKPIVALRDE
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
>Mature Secondary Structure
MFNIERWQEIFEAISKNRLRTFLTGISVASGIFILVILLGAGKGLQNGIEKQFERDAAGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
IEVWSGTTTKEYKGLNPGRQVQFRNSDYNQSTQKFEDKLDLRASTQNYWGQSFSYGKESG
EEECCCCCHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCC
SYQFRGVDPDYGGIENLTIVQGRYVNSKDLQNNEKVAVIGMKLKNDLLKDKDAIGEEILI
CEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHCCCHHEE
NNISFKVIGVFTDPGGEREETRAYLPLTTVQRTFGGGDKISNLFFTLKKTSNYDEALAQS
ECCCEEEEEEEECCCCCHHHCEEECCHHHHHHHCCCCHHHHHHHEEEECCCCHHHHHHHH
EKFTQDLKDLLKSKNMVAPDDDGGVGVYNSVKDAKQFYDLNLYIRLFFWWVGICTIIAGV
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGVSNIMLIIVKERTKEIGIRKALGASPFSIIAMILHESIFITTIAGFVGLLASLLLLEF
HHHCCEEEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGPMVQSEYFRNPEVDFSVALTTLFLLVFAGALAGFFPAYRAAKIKPIVALRDE
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA