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The map label for this gene is ruvB

Identifier: 146299402

GI number: 146299402

Start: 1897995

End: 1899017

Strand: Direct

Name: ruvB

Synonym: Fjoh_1642

Alternate gene names: 146299402

Gene position: 1897995-1899017 (Clockwise)

Preceding gene: 146299401

Following gene: 146299403

Centisome position: 31.13

GC content: 36.36

Gene sequence:

>1023_bases
ATGAATGAAAATCTAGATCCTACAACTAAAGGATATAACTCAGAAGAATTAGATCTTGAAAAAAGATTACGTCCGCTGTC
ATTTGACGATTTTGCCGGACAAGATCAAGTTTTGGAAAATTTAAAAGTCTTTGTTGCCGCTGCTAACCAACGTGGAGAGG
CACTTGATCATGCTTTGTTTCATGGACCTCCCGGACTTGGGAAAACGACTTTGGCAAATATTTTGGCAAATGAGCTGGAG
GTTGGAATCAAAATTACTTCTGGACCTGTTTTAGATAAACCTGGAGATTTAGCCGGATTGTTAACCAATCTAGATGAAAG
AGATGTTTTATTTATAGATGAAATTCATCGTTTGAGTCCAATTGTTGAAGAATACTTATACTCAGCAATGGAAGATTTTA
AAATTGATATTATGATTGAATCTGGTCCAAATGCCAGAACCGTTCAAATCAATTTAAATCCATTTACATTAATAGGAGCG
ACAACTCGTTCCGGATTATTAACAGCTCCAATGCGGGCTCGTTTTGGAATTTCATCACGTTTACAATATTATTCTACCGA
ACTTTTAACCACAATTGTAGAAAGAAGTGCTGGAATATTAAAAATGCCAATTGATCTTGAAGCTGCAATTGAAATTGCTG
GCCGAAGCAGAGGAACTCCTCGTATTGCAAATGCATTGTTGCGAAGAGTTAGAGATTTTGCTCAAATAAAAGGCAACGGT
ACGATTGATCTAGAGATTTCTAAATATGCATTGAAGGCATTGAATGTTGATGCTCATGGACTTGATGAAATGGATAATAA
GATATTATTGACCATTATTAATAAGTTTAAAGGCGGGCCAGTTGGTCTTTCTACCTTGGCGACAGCAGTTTCTGAAAGCA
GTGAAACTATTGAAGAAGTTTATGAACCTTTCTTGATTCAGGAAGGATTTATTATGCGTACACCCCGCGGGCGTGAAGTT
ACCGAGAAAGCATATAAACATTTAGGAAAGATAAACACAAATATACAAGGAGGTTTATTTTAA

Upstream 100 bases:

>100_bases
TATCAAAGGCTGTCAGAAATGACAGCCTTTTTTGTTTGGTTAAGGTTTAAACCTTAAGCTTACTGTTTTACAAACTAATT
AGTTTCTATATCTTTGCAGG

Downstream 100 bases:

>100_bases
ATTTTTATGTCTGAAAAACAAAAACATACTTATCCTGAAAAATTATCTATACTAAGATTTTTCAGAGATGCTGAAGGTGT
TCGCAGAAATCCGATTCCTT

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MNENLDPTTKGYNSEELDLEKRLRPLSFDDFAGQDQVLENLKVFVAAANQRGEALDHALFHGPPGLGKTTLANILANELE
VGIKITSGPVLDKPGDLAGLLTNLDERDVLFIDEIHRLSPIVEEYLYSAMEDFKIDIMIESGPNARTVQINLNPFTLIGA
TTRSGLLTAPMRARFGISSRLQYYSTELLTTIVERSAGILKMPIDLEAAIEIAGRSRGTPRIANALLRRVRDFAQIKGNG
TIDLEISKYALKALNVDAHGLDEMDNKILLTIINKFKGGPVGLSTLATAVSESSETIEEVYEPFLIQEGFIMRTPRGREV
TEKAYKHLGKINTNIQGGLF

Sequences:

>Translated_340_residues
MNENLDPTTKGYNSEELDLEKRLRPLSFDDFAGQDQVLENLKVFVAAANQRGEALDHALFHGPPGLGKTTLANILANELE
VGIKITSGPVLDKPGDLAGLLTNLDERDVLFIDEIHRLSPIVEEYLYSAMEDFKIDIMIESGPNARTVQINLNPFTLIGA
TTRSGLLTAPMRARFGISSRLQYYSTELLTTIVERSAGILKMPIDLEAAIEIAGRSRGTPRIANALLRRVRDFAQIKGNG
TIDLEISKYALKALNVDAHGLDEMDNKILLTIINKFKGGPVGLSTLATAVSESSETIEEVYEPFLIQEGFIMRTPRGREV
TEKAYKHLGKINTNIQGGLF
>Mature_340_residues
MNENLDPTTKGYNSEELDLEKRLRPLSFDDFAGQDQVLENLKVFVAAANQRGEALDHALFHGPPGLGKTTLANILANELE
VGIKITSGPVLDKPGDLAGLLTNLDERDVLFIDEIHRLSPIVEEYLYSAMEDFKIDIMIESGPNARTVQINLNPFTLIGA
TTRSGLLTAPMRARFGISSRLQYYSTELLTTIVERSAGILKMPIDLEAAIEIAGRSRGTPRIANALLRRVRDFAQIKGNG
TIDLEISKYALKALNVDAHGLDEMDNKILLTIINKFKGGPVGLSTLATAVSESSETIEEVYEPFLIQEGFIMRTPRGREV
TEKAYKHLGKINTNIQGGLF

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=310, Percent_Identity=59.0322580645161, Blast_Score=382, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_FLAJ1 (A5FJE5)

Other databases:

- EMBL:   CP000685
- RefSeq:   YP_001193993.1
- ProteinModelPortal:   A5FJE5
- SMR:   A5FJE5
- STRING:   A5FJE5
- GeneID:   5090993
- GenomeReviews:   CP000685_GR
- KEGG:   fjo:Fjoh_1642
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- BioCyc:   FJOH376686:FJOH_1642-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 37438; Mature: 37438

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNENLDPTTKGYNSEELDLEKRLRPLSFDDFAGQDQVLENLKVFVAAANQRGEALDHALF
CCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHEEEEECCCCCHHHHHHHH
HGPPGLGKTTLANILANELEVGIKITSGPVLDKPGDLAGLLTNLDERDVLFIDEIHRLSP
CCCCCCCHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHCCCCCCEEHHHHHHHHHH
IVEEYLYSAMEDFKIDIMIESGPNARTVQINLNPFTLIGATTRSGLLTAPMRARFGISSR
HHHHHHHHHHHCCEEEEEEECCCCCEEEEEECCCEEEEECCCCCCCEECCHHHHCCHHHH
LQYYSTELLTTIVERSAGILKMPIDLEAAIEIAGRSRGTPRIANALLRRVRDFAQIKGNG
HHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCC
TIDLEISKYALKALNVDAHGLDEMDNKILLTIINKFKGGPVGLSTLATAVSESSETIEEV
EEEEEEHHHHHHHHCCCCCCCHHHCCCEEEEEHHHCCCCCCCHHHHHHHHHCCHHHHHHH
YEPFLIQEGFIMRTPRGREVTEKAYKHLGKINTNIQGGLF
HHHHHHCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNENLDPTTKGYNSEELDLEKRLRPLSFDDFAGQDQVLENLKVFVAAANQRGEALDHALF
CCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHEEEEECCCCCHHHHHHHH
HGPPGLGKTTLANILANELEVGIKITSGPVLDKPGDLAGLLTNLDERDVLFIDEIHRLSP
CCCCCCCHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHCCCCCCEEHHHHHHHHHH
IVEEYLYSAMEDFKIDIMIESGPNARTVQINLNPFTLIGATTRSGLLTAPMRARFGISSR
HHHHHHHHHHHCCEEEEEEECCCCCEEEEEECCCEEEEECCCCCCCEECCHHHHCCHHHH
LQYYSTELLTTIVERSAGILKMPIDLEAAIEIAGRSRGTPRIANALLRRVRDFAQIKGNG
HHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCC
TIDLEISKYALKALNVDAHGLDEMDNKILLTIINKFKGGPVGLSTLATAVSESSETIEEV
EEEEEEHHHHHHHHCCCCCCCHHHCCCEEEEEHHHCCCCCCCHHHHHHHHHCCHHHHHHH
YEPFLIQEGFIMRTPRGREVTEKAYKHLGKINTNIQGGLF
HHHHHHCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA