| Definition | Flavobacterium johnsoniae UW101 chromosome, complete genome. |
|---|---|
| Accession | NC_009441 |
| Length | 6,096,872 |
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The map label for this gene is pbpC [H]
Identifier: 146299290
GI number: 146299290
Start: 1768494
End: 1770788
Strand: Direct
Name: pbpC [H]
Synonym: Fjoh_1530
Alternate gene names: 146299290
Gene position: 1768494-1770788 (Clockwise)
Preceding gene: 146299289
Following gene: 146299295
Centisome position: 29.01
GC content: 37.25
Gene sequence:
>2295_bases GTGCTCTTGCTGATTTACTATTTTTCAATACCTCGAACTTTGTTCAAAGAACCGTATTCAACCGTTATTGAAAGTAAAGA AGGAGAACTTCTTGGCGCTAAAATTGCGCGCGACGGACAATGGCGTTTTCCGGCGCAGGACAGTGTTCCAGATAAATTCA AGAAATGTATCGTTTATTTTGAAGATGAATACTTCTACAAACATCCCGGCTTCAATCCCGGCGCGATGATTAATGCTTTT AAGCAAAACAGAAAAGCAGGTAAAGTTGTTCGAGGCGGAAGTACGTTAACACAACAAGTTATTCGATTATCAAGAAAAGG AAAAAACAGGACCTACTTTGAAAAACTAATAGAAATTATTCTCGCTACAAGATTAGAATTAGGTTATTCTAAGAATGAAA TTCTCGAAATGTATGCAGCGCACGCTCCTTTTGGAGGAAATGTTGTGGGATTGGAAATGGCTTCATGGCGTTATTTTGGA GTACAATCGAATCAATTATCTTGGGCAGAAAATGCAGTTTTGGCTGTTTTACCCAATGCACCAAGTTTAATTTATCCTGG AAAAAATCAGATAAAATTACTCAACAAACGAAATCGTCTTTTATTAAAACTGCATCAGGAAGGCATAATCGATAAACAGA CGTACGAACTTTCGATAGAAGAACCATTGCCTCAAAAACCGTATGATCTGCCTCAAATAGCGCCTCATTTATTACAGAGA GTGGCAAAAAATGAAGAAGGAACAAGAGTAAAAACTACAATTGATTATGCGTTGCAAAATCGTGTCAACCAAATCGCGAG ATATTATTACAATCAGTATAAGCAGAATGAAGTGCATAATCTGGCTATTTTGGTAATCGATGTTCAGAATCGAAATGTAA TAAGTTATGTAGGGAATTCTCCAACAGATAAAGACCATCAAAAAGATGTTGATATTATTGATGCGCCACGAAGTACAGGC AGTATTTTAAAACCGCTTTTGTACGGAGCAATGTTGGATGACGGCGAATTATTGCCCAATACTTTAGTGGCTGATATTCC AACGCAGATTTCAGGATATACGCCTCAAAATTTCAACCTAACATTTGATGGGGCAGTTCCAGCTCATCGTGCATTGTCGC GTTCGTTGAATATTCCTGCGGTTTTAATGCTTCAGGAATTTACGGTAAACAAGTTTTACGAAGAGCTTCAAAAATTCAAG TTAAAGAATATTAATAAAACGCCGGATCATTATGGTTTGTCGCTTATTTTGGGTGGTGCAGAAAGTAATTTATGGGATTT ATGCCGAACATACGCAAATCTTTCATCTACGGTCAATTATTATACTAAAAATAAAGGGCAATATAGAACCAACGAGTTCA CAGAGCTGAATTACAAAAACGATTTTAAGCCTGATTTTGGTTCTGAAACTGATCAAAAGAATATTTTGGGCGCAGGATCA ATTTGGTTAACCTACAACGCAATGGAAGAGGTTAATAGGCCTGAAGGAGACGAAGCTTGGAAGTTTTATGACAGTTCTTT AAAAATTGCATGGAAAACGGGAACAAGTTTTGGAAATCGAGATGCATGGGCTATTGGAACAAATTCAAGATATGTAGTTG GAATTTGGGTTGGAAATGCGACGGGAGAGGGAAGGCCAACTTTGACAGGAGTAACCAGTGCTGCGCCAATTTTATTTGAT GTTTTTAATTTACTGCCAAGACAACGATGGTTTGATACGCCGTATAATGATTTGTCCGAAGTTGAGGTTTGTCGTTTAAG CGGTTATTTGGCAAAAGACAACTGTCCGAAAATTAAACAATGGGTTACTAAAAAAGGTAAATCGACCAAGGTCTGTCCGT ATCACAGAACAATTCATTTAGATAAAACAGAGCAGTTTCAGGTAAACAGCAGCTGCGAGAACATCGATAATATTGTTACT AAAAACTGGTTTGTACTACCTCCAGTTATGGCTTGGTATTACAAAAGCCAGCATATCGAATATTTGCCGTTACCGCCATT CAAAGAAGGATGCGAAGGAACACAGACTACTACAATGGACTTTATTTATCCGAAAGCGAATAGTAAAATCTATTTGACAA AGGACTTTAACAGCAACGTACAGCCCGTAATTTTAAAAGTAGCGTATTCTGAAAGAGATAAAGAATTATTCTGGTATGTT GATGATGTTTATAAAGCAACGACAAAAACATTTCATGAACTGCCTATTACGCCAACAACAGGAATACATTATATCACGGT TGTAGATGCTTCTGGAAATGAAATTAGACGCAGAATCGAGATTGTAAGAGAATAA
Upstream 100 bases:
>100_bases GCTAAAACCTTTAAATGTTTTGAAAAATAAACTTATAGCGTTTTTCCAACGCGTCATAAACTGGATTAAAAGAAATAAAA TAAAATCAGCAATTGCATTT
Downstream 100 bases:
>100_bases AATCTATTACATAACTTTGAGTTGGTTGTATGCATTTTTATTATTTGTGATTCGAAAAGTAATTGAAGTTGTGAATCCTT GATAAGTTGGAATTTTTTCT
Product: penicillin-binding protein 1C
Products: NA
Alternate protein names: PBP-1c; PBP1c; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Transpeptidase-like module [H]
Number of amino acids: Translated: 764; Mature: 764
Protein sequence:
>764_residues MLLLIYYFSIPRTLFKEPYSTVIESKEGELLGAKIARDGQWRFPAQDSVPDKFKKCIVYFEDEYFYKHPGFNPGAMINAF KQNRKAGKVVRGGSTLTQQVIRLSRKGKNRTYFEKLIEIILATRLELGYSKNEILEMYAAHAPFGGNVVGLEMASWRYFG VQSNQLSWAENAVLAVLPNAPSLIYPGKNQIKLLNKRNRLLLKLHQEGIIDKQTYELSIEEPLPQKPYDLPQIAPHLLQR VAKNEEGTRVKTTIDYALQNRVNQIARYYYNQYKQNEVHNLAILVIDVQNRNVISYVGNSPTDKDHQKDVDIIDAPRSTG SILKPLLYGAMLDDGELLPNTLVADIPTQISGYTPQNFNLTFDGAVPAHRALSRSLNIPAVLMLQEFTVNKFYEELQKFK LKNINKTPDHYGLSLILGGAESNLWDLCRTYANLSSTVNYYTKNKGQYRTNEFTELNYKNDFKPDFGSETDQKNILGAGS IWLTYNAMEEVNRPEGDEAWKFYDSSLKIAWKTGTSFGNRDAWAIGTNSRYVVGIWVGNATGEGRPTLTGVTSAAPILFD VFNLLPRQRWFDTPYNDLSEVEVCRLSGYLAKDNCPKIKQWVTKKGKSTKVCPYHRTIHLDKTEQFQVNSSCENIDNIVT KNWFVLPPVMAWYYKSQHIEYLPLPPFKEGCEGTQTTTMDFIYPKANSKIYLTKDFNSNVQPVILKVAYSERDKELFWYV DDVYKATTKTFHELPITPTTGIHYITVVDASGNEIRRRIEIVRE
Sequences:
>Translated_764_residues MLLLIYYFSIPRTLFKEPYSTVIESKEGELLGAKIARDGQWRFPAQDSVPDKFKKCIVYFEDEYFYKHPGFNPGAMINAF KQNRKAGKVVRGGSTLTQQVIRLSRKGKNRTYFEKLIEIILATRLELGYSKNEILEMYAAHAPFGGNVVGLEMASWRYFG VQSNQLSWAENAVLAVLPNAPSLIYPGKNQIKLLNKRNRLLLKLHQEGIIDKQTYELSIEEPLPQKPYDLPQIAPHLLQR VAKNEEGTRVKTTIDYALQNRVNQIARYYYNQYKQNEVHNLAILVIDVQNRNVISYVGNSPTDKDHQKDVDIIDAPRSTG SILKPLLYGAMLDDGELLPNTLVADIPTQISGYTPQNFNLTFDGAVPAHRALSRSLNIPAVLMLQEFTVNKFYEELQKFK LKNINKTPDHYGLSLILGGAESNLWDLCRTYANLSSTVNYYTKNKGQYRTNEFTELNYKNDFKPDFGSETDQKNILGAGS IWLTYNAMEEVNRPEGDEAWKFYDSSLKIAWKTGTSFGNRDAWAIGTNSRYVVGIWVGNATGEGRPTLTGVTSAAPILFD VFNLLPRQRWFDTPYNDLSEVEVCRLSGYLAKDNCPKIKQWVTKKGKSTKVCPYHRTIHLDKTEQFQVNSSCENIDNIVT KNWFVLPPVMAWYYKSQHIEYLPLPPFKEGCEGTQTTTMDFIYPKANSKIYLTKDFNSNVQPVILKVAYSERDKELFWYV DDVYKATTKTFHELPITPTTGIHYITVVDASGNEIRRRIEIVRE >Mature_764_residues MLLLIYYFSIPRTLFKEPYSTVIESKEGELLGAKIARDGQWRFPAQDSVPDKFKKCIVYFEDEYFYKHPGFNPGAMINAF KQNRKAGKVVRGGSTLTQQVIRLSRKGKNRTYFEKLIEIILATRLELGYSKNEILEMYAAHAPFGGNVVGLEMASWRYFG VQSNQLSWAENAVLAVLPNAPSLIYPGKNQIKLLNKRNRLLLKLHQEGIIDKQTYELSIEEPLPQKPYDLPQIAPHLLQR VAKNEEGTRVKTTIDYALQNRVNQIARYYYNQYKQNEVHNLAILVIDVQNRNVISYVGNSPTDKDHQKDVDIIDAPRSTG SILKPLLYGAMLDDGELLPNTLVADIPTQISGYTPQNFNLTFDGAVPAHRALSRSLNIPAVLMLQEFTVNKFYEELQKFK LKNINKTPDHYGLSLILGGAESNLWDLCRTYANLSSTVNYYTKNKGQYRTNEFTELNYKNDFKPDFGSETDQKNILGAGS IWLTYNAMEEVNRPEGDEAWKFYDSSLKIAWKTGTSFGNRDAWAIGTNSRYVVGIWVGNATGEGRPTLTGVTSAAPILFD VFNLLPRQRWFDTPYNDLSEVEVCRLSGYLAKDNCPKIKQWVTKKGKSTKVCPYHRTIHLDKTEQFQVNSSCENIDNIVT KNWFVLPPVMAWYYKSQHIEYLPLPPFKEGCEGTQTTTMDFIYPKANSKIYLTKDFNSNVQPVILKVAYSERDKELFWYV DDVYKATTKTFHELPITPTTGIHYITVVDASGNEIRRRIEIVRE
Specific function: Cell wall formation. The enzyme has a penicillin- insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a transpeptidase C-terminal domain which may not be functional [H]
COG id: COG4953
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein PbpC
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1788867, Length=552, Percent_Identity=34.2391304347826, Blast_Score=309, Evalue=4e-85, Organism=Escherichia coli, GI1786343, Length=569, Percent_Identity=27.4165202108963, Blast_Score=124, Evalue=2e-29, Organism=Escherichia coli, GI87082258, Length=338, Percent_Identity=30.4733727810651, Blast_Score=112, Evalue=7e-26, Organism=Escherichia coli, GI1789601, Length=124, Percent_Identity=34.6774193548387, Blast_Score=72, Evalue=2e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011815 - InterPro: IPR009647 - InterPro: IPR001460 [H]
Pfam domain/function: PF06832 BiPBP_C; PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-
Molecular weight: Translated: 87461; Mature: 87461
Theoretical pI: Translated: 8.91; Mature: 8.91
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 1.2 %Met (Translated Protein) 2.1 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 2.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLLLIYYFSIPRTLFKEPYSTVIESKEGELLGAKIARDGQWRFPAQDSVPDKFKKCIVYF CEEEEEEHHCCHHHHHCHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHEEEEE EDEYFYKHPGFNPGAMINAFKQNRKAGKVVRGGSTLTQQVIRLSRKGKNRTYFEKLIEII ECCEEEECCCCCCHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHH LATRLELGYSKNEILEMYAAHAPFGGNVVGLEMASWRYFGVQSNQLSWAENAVLAVLPNA HHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEEECEEEECCCCCCCCCCCCEEEEEECCC PSLIYPGKNQIKLLNKRNRLLLKLHQEGIIDKQTYELSIEEPLPQKPYDLPQIAPHLLQR CCEEECCCCCEEEECCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHH VAKNEEGTRVKTTIDYALQNRVNQIARYYYNQYKQNEVHNLAILVIDVQNRNVISYVGNS HHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCEEEECCCC PTDKDHQKDVDIIDAPRSTGSILKPLLYGAMLDDGELLPNTLVADIPTQISGYTPQNFNL CCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHCCCCCCCCCE TFDGAVPAHRALSRSLNIPAVLMLQEFTVNKFYEELQKFKLKNINKTPDHYGLSLILGGA EECCCCCHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECC ESNLWDLCRTYANLSSTVNYYTKNKGQYRTNEFTELNYKNDFKPDFGSETDQKNILGAGS CCCHHHHHHHHHHHHHHEEEEECCCCCEECCCEEECCCCCCCCCCCCCCCCCCCCEECCE IWLTYNAMEEVNRPEGDEAWKFYDSSLKIAWKTGTSFGNRDAWAIGTNSRYVVGIWVGNA EEEEEECHHHCCCCCCCCHHEEECCCEEEEEECCCCCCCCCEEEEECCCEEEEEEEEECC TGEGRPTLTGVTSAAPILFDVFNLLPRQRWFDTPYNDLSEVEVCRLSGYLAKDNCPKIKQ CCCCCCCEEECCHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHHCCEECCCCCHHHHH WVTKKGKSTKVCPYHRTIHLDKTEQFQVNSSCENIDNIVTKNWFVLPPVMAWYYKSQHIE HHHCCCCCCCCCCCEEEEEECCCCCEEECCCHHHHHHHHHCCEEECCHHHHHHHHCCCCE YLPLPPFKEGCEGTQTTTMDFIYPKANSKIYLTKDFNSNVQPVILKVAYSERDKELFWYV ECCCCCCHHCCCCCCCEEEEEEEECCCCEEEEEECCCCCCCEEEEEEEECCCCCEEEEEE DDVYKATTKTFHELPITPTTGIHYITVVDASGNEIRRRIEIVRE HHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCHHHHHHHHHHCC >Mature Secondary Structure MLLLIYYFSIPRTLFKEPYSTVIESKEGELLGAKIARDGQWRFPAQDSVPDKFKKCIVYF CEEEEEEHHCCHHHHHCHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHEEEEE EDEYFYKHPGFNPGAMINAFKQNRKAGKVVRGGSTLTQQVIRLSRKGKNRTYFEKLIEII ECCEEEECCCCCCHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHH LATRLELGYSKNEILEMYAAHAPFGGNVVGLEMASWRYFGVQSNQLSWAENAVLAVLPNA HHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEEECEEEECCCCCCCCCCCCEEEEEECCC PSLIYPGKNQIKLLNKRNRLLLKLHQEGIIDKQTYELSIEEPLPQKPYDLPQIAPHLLQR CCEEECCCCCEEEECCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHH VAKNEEGTRVKTTIDYALQNRVNQIARYYYNQYKQNEVHNLAILVIDVQNRNVISYVGNS HHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCEEEECCCC PTDKDHQKDVDIIDAPRSTGSILKPLLYGAMLDDGELLPNTLVADIPTQISGYTPQNFNL CCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHCCCCCCCCCE TFDGAVPAHRALSRSLNIPAVLMLQEFTVNKFYEELQKFKLKNINKTPDHYGLSLILGGA EECCCCCHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECC ESNLWDLCRTYANLSSTVNYYTKNKGQYRTNEFTELNYKNDFKPDFGSETDQKNILGAGS CCCHHHHHHHHHHHHHHEEEEECCCCCEECCCEEECCCCCCCCCCCCCCCCCCCCEECCE IWLTYNAMEEVNRPEGDEAWKFYDSSLKIAWKTGTSFGNRDAWAIGTNSRYVVGIWVGNA EEEEEECHHHCCCCCCCCHHEEECCCEEEEEECCCCCCCCCEEEEECCCEEEEEEEEECC TGEGRPTLTGVTSAAPILFDVFNLLPRQRWFDTPYNDLSEVEVCRLSGYLAKDNCPKIKQ CCCCCCCEEECCHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHHCCEECCCCCHHHHH WVTKKGKSTKVCPYHRTIHLDKTEQFQVNSSCENIDNIVTKNWFVLPPVMAWYYKSQHIE HHHCCCCCCCCCCCEEEEEECCCCCEEECCCHHHHHHHHHCCEEECCHHHHHHHHCCCCE YLPLPPFKEGCEGTQTTTMDFIYPKANSKIYLTKDFNSNVQPVILKVAYSERDKELFWYV ECCCCCCHHCCCCCCCEEEEEEEECCCCEEEEEECCCCCCCEEEEEEEECCCCCEEEEEE DDVYKATTKTFHELPITPTTGIHYITVVDASGNEIRRRIEIVRE HHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 10542235; 9205837; 9278503; 9841666 [H]