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The map label for this gene is macB [H]

Identifier: 146299220

GI number: 146299220

Start: 1673609

End: 1674856

Strand: Direct

Name: macB [H]

Synonym: Fjoh_1460

Alternate gene names: 146299220

Gene position: 1673609-1674856 (Clockwise)

Preceding gene: 146299213

Following gene: 146299225

Centisome position: 27.45

GC content: 33.97

Gene sequence:

>1248_bases
ATGCTTCTTTATCTAAGATTATTAAAAGAAAGTCTAAGCTTTGCCATAAACGCTTTACGAAATAATAAACTTCGTACTTT
GTTGTCGTTATTGGGTGTTACAATTGGTATTTTTTCAATAATTGCCGTCTTGGCTGCAGTTGATTCTTTAGACAAAAAAA
TCTCTAAAGATTTGAGCAGTTTAGATAAAAATACGATTTATTTAATGAAATTCAGTTTTGGGCCTTCAGAAATTCCACAA
TGGAAGAGAGAACAGTTTCCAAATGTGAAATATGATGAATATGTTAACTTAAAAAATTCTCTTAATAATACAGATCAGGT
TGGGTATCAGCTTTGGGTTAATAAAGAAACTTTAAAATATGATTCTAAAACTGTAGCCGATGTAAGGATTAATCCATCTT
CATTTGAAATGGGGGATATTGATGGTTTAAGTTTTGAAAAAGGACGATTTTATAATGAATCTGAATCGAACTCAGGAACT
GCTGTAATTGTTTTGGGATACGAAATTGCTCAGGGACTTTTTGGGGATATTGATCCAATTGGTAAAAATATCCGATTGTA
TGGCCAGCGTTTTACTGTAATTGGTGTAATTGCCAAACAAGGTGCGGGTTTTTTTGGAGACAGTAATGATACATCAGTTT
ATCTGCCGGCTAATTTTTTACGCCGAATGTATGGCGACAGCGATGCAATGACTCCAATGATTATTTTAAAACCTACTAAA
GGTGTTGATATGGAAGCTTATAAAGCTGAAGTTTCCCAAAAATTAAGAGCAATTCGCGGAATGAAAGCAGGAGAAATGGA
TAACTTTTTCATAAATGTGCTTTCTGGTTTTACTGATTTTATCGACGGAATTTTAGGCCAGATGAATGTAGTAGGGTGGA
TTATCAGCGGATTTTCTCTTTTGGTCGGCGGTTTCGGAATTGCCAATATTATGTTTGTATCGGTTAAAGAAAGAACCAAT
TTAATTGGTATTCAAAAATCATTGGGAGCCAAAAACAGATTTATATTATTTCAGTTTTTATTTGAAGCTATAATTCTCTC
TGTAATTGGCGGAATTATTGGTTTATTGATGGTTTGGGGAATTGCAGTTATTTTAACCAAAGCACTGGATTTTGAATTTG
TATTGAGCTTTGGAAATATAATTTTGGGAACAACTTTAGCGGCGCTTATTGGATTGATTTCGGGTATTCTGCCGGCTATT
TCTGCAGCAAATCTTGATCCTGTAGAAGCAATTAGAACAGGGATGTAG

Upstream 100 bases:

>100_bases
GTAACAATCTCGTAAAAAAATCTACTGATGAGTAAGTTAACTTTTATTAGGTTTTTGTTTTTAAATTATTGAATTTTACT
TTATTGAAAAATACTACTAT

Downstream 100 bases:

>100_bases
TTTTTTTGGAAGATTAAAAGGGGCTTGGATAATAAGGTTCTGAGTTTTTTGTAAATGAAAAATATTTTAAAGTGCCATAA
AGTTTTTCCCTGCTTTGTCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MLLYLRLLKESLSFAINALRNNKLRTLLSLLGVTIGIFSIIAVLAAVDSLDKKISKDLSSLDKNTIYLMKFSFGPSEIPQ
WKREQFPNVKYDEYVNLKNSLNNTDQVGYQLWVNKETLKYDSKTVADVRINPSSFEMGDIDGLSFEKGRFYNESESNSGT
AVIVLGYEIAQGLFGDIDPIGKNIRLYGQRFTVIGVIAKQGAGFFGDSNDTSVYLPANFLRRMYGDSDAMTPMIILKPTK
GVDMEAYKAEVSQKLRAIRGMKAGEMDNFFINVLSGFTDFIDGILGQMNVVGWIISGFSLLVGGFGIANIMFVSVKERTN
LIGIQKSLGAKNRFILFQFLFEAIILSVIGGIIGLLMVWGIAVILTKALDFEFVLSFGNIILGTTLAALIGLISGILPAI
SAANLDPVEAIRTGM

Sequences:

>Translated_415_residues
MLLYLRLLKESLSFAINALRNNKLRTLLSLLGVTIGIFSIIAVLAAVDSLDKKISKDLSSLDKNTIYLMKFSFGPSEIPQ
WKREQFPNVKYDEYVNLKNSLNNTDQVGYQLWVNKETLKYDSKTVADVRINPSSFEMGDIDGLSFEKGRFYNESESNSGT
AVIVLGYEIAQGLFGDIDPIGKNIRLYGQRFTVIGVIAKQGAGFFGDSNDTSVYLPANFLRRMYGDSDAMTPMIILKPTK
GVDMEAYKAEVSQKLRAIRGMKAGEMDNFFINVLSGFTDFIDGILGQMNVVGWIISGFSLLVGGFGIANIMFVSVKERTN
LIGIQKSLGAKNRFILFQFLFEAIILSVIGGIIGLLMVWGIAVILTKALDFEFVLSFGNIILGTTLAALIGLISGILPAI
SAANLDPVEAIRTGM
>Mature_415_residues
MLLYLRLLKESLSFAINALRNNKLRTLLSLLGVTIGIFSIIAVLAAVDSLDKKISKDLSSLDKNTIYLMKFSFGPSEIPQ
WKREQFPNVKYDEYVNLKNSLNNTDQVGYQLWVNKETLKYDSKTVADVRINPSSFEMGDIDGLSFEKGRFYNESESNSGT
AVIVLGYEIAQGLFGDIDPIGKNIRLYGQRFTVIGVIAKQGAGFFGDSNDTSVYLPANFLRRMYGDSDAMTPMIILKPTK
GVDMEAYKAEVSQKLRAIRGMKAGEMDNFFINVLSGFTDFIDGILGQMNVVGWIISGFSLLVGGFGIANIMFVSVKERTN
LIGIQKSLGAKNRFILFQFLFEAIILSVIGGIIGLLMVWGIAVILTKALDFEFVLSFGNIILGTTLAALIGLISGILPAI
SAANLDPVEAIRTGM

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=415, Percent_Identity=31.0843373493976, Blast_Score=144, Evalue=8e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45614; Mature: 45614

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLYLRLLKESLSFAINALRNNKLRTLLSLLGVTIGIFSIIAVLAAVDSLDKKISKDLSS
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDKNTIYLMKFSFGPSEIPQWKREQFPNVKYDEYVNLKNSLNNTDQVGYQLWVNKETLKY
CCCCEEEEEEECCCCCCCCCHHHHHCCCCCHHHHCCHHHHCCCCHHCCEEEEECCHHHHC
DSKTVADVRINPSSFEMGDIDGLSFEKGRFYNESESNSGTAVIVLGYEIAQGLFGDIDPI
CCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHCCCCCCC
GKNIRLYGQRFTVIGVIAKQGAGFFGDSNDTSVYLPANFLRRMYGDSDAMTPMIILKPTK
CCCEEEECCEEEEEEEEHHCCCCCCCCCCCCEEEECHHHHHHHHCCCCCCCCEEEEECCC
GVDMEAYKAEVSQKLRAIRGMKAGEMDNFFINVLSGFTDFIDGILGQMNVVGWIISGFSL
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVGGFGIANIMFVSVKERTNLIGIQKSLGAKNRFILFQFLFEAIILSVIGGIIGLLMVWG
HHHCCCHHHEEEEEEHHHCCCEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAVILTKALDFEFVLSFGNIILGTTLAALIGLISGILPAISAANLDPVEAIRTGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCC
>Mature Secondary Structure
MLLYLRLLKESLSFAINALRNNKLRTLLSLLGVTIGIFSIIAVLAAVDSLDKKISKDLSS
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDKNTIYLMKFSFGPSEIPQWKREQFPNVKYDEYVNLKNSLNNTDQVGYQLWVNKETLKY
CCCCEEEEEEECCCCCCCCCHHHHHCCCCCHHHHCCHHHHCCCCHHCCEEEEECCHHHHC
DSKTVADVRINPSSFEMGDIDGLSFEKGRFYNESESNSGTAVIVLGYEIAQGLFGDIDPI
CCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHCCCCCCC
GKNIRLYGQRFTVIGVIAKQGAGFFGDSNDTSVYLPANFLRRMYGDSDAMTPMIILKPTK
CCCEEEECCEEEEEEEEHHCCCCCCCCCCCCEEEECHHHHHHHHCCCCCCCCEEEEECCC
GVDMEAYKAEVSQKLRAIRGMKAGEMDNFFINVLSGFTDFIDGILGQMNVVGWIISGFSL
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVGGFGIANIMFVSVKERTNLIGIQKSLGAKNRFILFQFLFEAIILSVIGGIIGLLMVWG
HHHCCCHHHEEEEEEHHHCCCEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAVILTKALDFEFVLSFGNIILGTTLAALIGLISGILPAISAANLDPVEAIRTGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA