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The map label for this gene is alr2 [H]

Identifier: 146299078

GI number: 146299078

Start: 1508552

End: 1511020

Strand: Direct

Name: alr2 [H]

Synonym: Fjoh_1318

Alternate gene names: 146299078

Gene position: 1508552-1511020 (Clockwise)

Preceding gene: 146299076

Following gene: 146299079

Centisome position: 24.74

GC content: 34.31

Gene sequence:

>2469_bases
ATGAGCATAAATTTAAAAAGCCTGATTCCGGTTTTAAATGCCGAGTGGACAGGCTCAGATACTGATATTTTTGTAGATCA
TATTTCGATCGACAGCCGTTCTTTACAAAACGGACCTCAAACATTGTTTATTGCTCTTTCGGGCGCGAATAATGACGCTC
ATTTATATATTGCCGAATTAATAGAAAAAGGCGTTCAGAATTTTGCAGTTCAGTATATACCAGAAAATGTAAAAGGAAAA
GCCAATTTTTTTGTTGTAAAAAATACGCTGAAAGCATTACAGGAATTAGCAGCCTATTATCGTGATTTATTCGATTTCCC
TATTATTGGTTTAACCGGAAGCAACGGAAAAACCATCGTAAAAGAATGGCTTAATTTTCTTTTAAGCCCTGATTATAATA
TTATCCGAAGCCCAAAAAGTTATAACTCACAAGTTGGTGTTCCGCTTTCTGTTATTGCTATAAATGAAAAACACAATTTA
GGAATTTTTGAAGCCGGAATTTCAACGGTTAACGAAATGGTTAATCTTGAGAAAATTATCAAACCAAATATTGGAGTTTT
AACCAATATAGGTTCTGCACACGATGAAGGATTTGAAAATCTGACTCAGAAAATCAACGAGAAATTACTGCTTTTCAAAA
AGTCAGCAGTAATTATTTATCAAAAAAATGAATTGGTAGATAAATGTCTTTTAGACTTTTCTGCTCAATATCCGCTAGAA
AACAGAGCCTTATTTTCATGGAGTTTTGCAGATGCCTCTGCAGATGTTTTTATTCTGAAAAAAGAAACCAAAAACGATTC
AACCACAATAAAATATCAATATAAAGACGAAATTTTTAATTTAGAAATTCCGTTCAGCGATTCTGCTTCTATCGAAAATG
CCATTTCATGTTTATTGGTTTTACTGCATTTTGAATATGATTTTACCATTATTCAAAACAGAATGGAAATGCTTTATCCA
GTTGAAATGCGTCTTGAAGTTAAAAACGGAATCCACAATTGCAGTTTAATAGACGATAGTTACAGCTCCGATTTTCAATC
GCTGAAAATCGCTTTAGATTTTCTGGAAAGCCAGAAAAAAAATGCTTCAAAAGCCGTTATACTATCAGATATTTTTCAAA
GCGGATTTTCAAATGAAGAACTGTATTCAAAAGTAGCGCAGTTAATTTCAGATAATAAAATAAACCGTGTCATTGGAATT
GGAACTACAATTTCATCTTTTCAAGATAAGTTTCCAAACAGTACGATGTTTCAAAACACGGCTGCATTTATCGCCGAAAT
TGAAAATTTGAATTTCAATAATGAAACCATATTGATAAAAGGCGCAAGATCATTTCAGTTTGAAGAAATTGTTTCACTGC
TTGAAGAAAAAACGCATGAAACAGTTCTCGAAATCAATCTGGATGCTATAAATCACAATCTGAATTATTTTAAATCAAAA
CTGGCCGATGATGTAAAAATCATGGTTATGGTCAAGGCTTTTGGTTATGGAAACGGCGGACTCGAAATTGCAAAACTGCT
CGAACATAATAAAGTAAATTATTTAGGTGTGGCTTTCGCCGATGAAGGAATTTCGCTGAAAAATGGCGGCATCAAACTGC
CTATTATGGTTTTGAATCCAGAATCGACCAGCTTTCCTTCGATAATTCAATACAAACTTGAACCCGAAATTTACAGCATA
AAAGGTTTAAATGCCTTTTTGAAAATAGCCAGAGAAAAGAACTTAAAAGATTTTCCTATTCATATAAAAGTCGATACAGG
AATGCACCGTTTAGGTTTTGAGGATAATACGATCGACGAATTAATTGCGACTTTAAAAGGAAACTCAACCGTTCGTGTTC
AAAGTATTTTATCGCATTTGGCAACGAGCGATGATCCGAAGCATTTTGATTTTGTAGAAAAACAAATAAGTTTATTCGAA
AGGTTATCTTCAAAATTAATCTCAGAATTAAATATAAATCCAATCCGCCATATTTTAAACACTTCCGGAATCAGTAATTT
CCCAGATGCACAATACAATATGGTGCGTTTAGGGATTGGTTTGTATGGCGTTTCCAACGATCCGGCCGAACAGAAATATC
TGGAAAACGTAGGCACCTTAAAATCGATTATTTCGCAGGTTCGAACTATTCCGGCAGGTGACAGCGTTGGTTACGGACGC
CGTTTTATGGCAGATAAAGAAACAAAAATTGCAACCATTCCAATTGGTTATGCAGACGGAATTTCGAGATTATGGGGCAA
TCAGATTGGTTTTGTAACCATCAAAAATCAAAAAGCCTATATCGTAGGAAGTGTTTGTATGGATATGTTAATGGTTGATG
TAAGTCATATAGACTGCAAAGAAGGCGATTCGGTAATTATTTTCGGCGAAAGCCCAACGGTTATAGAAATGGCTGAAGCA
TTAAAAACCATTCCGTATGAAATAATGACCAGTATTTCGCAGCGTGTAAAACGAGTATTTTTTAGATAG

Upstream 100 bases:

>100_bases
AATTTGTGGAAATTTGTGTAATTCGCGGCAAACTCTTTTTTATATCTAAAAATGAATTCGTGGCAAACCTTTTTTTAAAT
TTGACAAAAAGAATTTCTAA

Downstream 100 bases:

>100_bases
AGTACCGAACTTTCAGGAAAATTGCGTATTTTCGATATTCAATTATTATAAACAAAAACAGATCAGATATGGGATTTTTT
TCAGAATTTAAGGAATTTGC

Product: putative bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 822; Mature: 821

Protein sequence:

>822_residues
MSINLKSLIPVLNAEWTGSDTDIFVDHISIDSRSLQNGPQTLFIALSGANNDAHLYIAELIEKGVQNFAVQYIPENVKGK
ANFFVVKNTLKALQELAAYYRDLFDFPIIGLTGSNGKTIVKEWLNFLLSPDYNIIRSPKSYNSQVGVPLSVIAINEKHNL
GIFEAGISTVNEMVNLEKIIKPNIGVLTNIGSAHDEGFENLTQKINEKLLLFKKSAVIIYQKNELVDKCLLDFSAQYPLE
NRALFSWSFADASADVFILKKETKNDSTTIKYQYKDEIFNLEIPFSDSASIENAISCLLVLLHFEYDFTIIQNRMEMLYP
VEMRLEVKNGIHNCSLIDDSYSSDFQSLKIALDFLESQKKNASKAVILSDIFQSGFSNEELYSKVAQLISDNKINRVIGI
GTTISSFQDKFPNSTMFQNTAAFIAEIENLNFNNETILIKGARSFQFEEIVSLLEEKTHETVLEINLDAINHNLNYFKSK
LADDVKIMVMVKAFGYGNGGLEIAKLLEHNKVNYLGVAFADEGISLKNGGIKLPIMVLNPESTSFPSIIQYKLEPEIYSI
KGLNAFLKIAREKNLKDFPIHIKVDTGMHRLGFEDNTIDELIATLKGNSTVRVQSILSHLATSDDPKHFDFVEKQISLFE
RLSSKLISELNINPIRHILNTSGISNFPDAQYNMVRLGIGLYGVSNDPAEQKYLENVGTLKSIISQVRTIPAGDSVGYGR
RFMADKETKIATIPIGYADGISRLWGNQIGFVTIKNQKAYIVGSVCMDMLMVDVSHIDCKEGDSVIIFGESPTVIEMAEA
LKTIPYEIMTSISQRVKRVFFR

Sequences:

>Translated_822_residues
MSINLKSLIPVLNAEWTGSDTDIFVDHISIDSRSLQNGPQTLFIALSGANNDAHLYIAELIEKGVQNFAVQYIPENVKGK
ANFFVVKNTLKALQELAAYYRDLFDFPIIGLTGSNGKTIVKEWLNFLLSPDYNIIRSPKSYNSQVGVPLSVIAINEKHNL
GIFEAGISTVNEMVNLEKIIKPNIGVLTNIGSAHDEGFENLTQKINEKLLLFKKSAVIIYQKNELVDKCLLDFSAQYPLE
NRALFSWSFADASADVFILKKETKNDSTTIKYQYKDEIFNLEIPFSDSASIENAISCLLVLLHFEYDFTIIQNRMEMLYP
VEMRLEVKNGIHNCSLIDDSYSSDFQSLKIALDFLESQKKNASKAVILSDIFQSGFSNEELYSKVAQLISDNKINRVIGI
GTTISSFQDKFPNSTMFQNTAAFIAEIENLNFNNETILIKGARSFQFEEIVSLLEEKTHETVLEINLDAINHNLNYFKSK
LADDVKIMVMVKAFGYGNGGLEIAKLLEHNKVNYLGVAFADEGISLKNGGIKLPIMVLNPESTSFPSIIQYKLEPEIYSI
KGLNAFLKIAREKNLKDFPIHIKVDTGMHRLGFEDNTIDELIATLKGNSTVRVQSILSHLATSDDPKHFDFVEKQISLFE
RLSSKLISELNINPIRHILNTSGISNFPDAQYNMVRLGIGLYGVSNDPAEQKYLENVGTLKSIISQVRTIPAGDSVGYGR
RFMADKETKIATIPIGYADGISRLWGNQIGFVTIKNQKAYIVGSVCMDMLMVDVSHIDCKEGDSVIIFGESPTVIEMAEA
LKTIPYEIMTSISQRVKRVFFR
>Mature_821_residues
SINLKSLIPVLNAEWTGSDTDIFVDHISIDSRSLQNGPQTLFIALSGANNDAHLYIAELIEKGVQNFAVQYIPENVKGKA
NFFVVKNTLKALQELAAYYRDLFDFPIIGLTGSNGKTIVKEWLNFLLSPDYNIIRSPKSYNSQVGVPLSVIAINEKHNLG
IFEAGISTVNEMVNLEKIIKPNIGVLTNIGSAHDEGFENLTQKINEKLLLFKKSAVIIYQKNELVDKCLLDFSAQYPLEN
RALFSWSFADASADVFILKKETKNDSTTIKYQYKDEIFNLEIPFSDSASIENAISCLLVLLHFEYDFTIIQNRMEMLYPV
EMRLEVKNGIHNCSLIDDSYSSDFQSLKIALDFLESQKKNASKAVILSDIFQSGFSNEELYSKVAQLISDNKINRVIGIG
TTISSFQDKFPNSTMFQNTAAFIAEIENLNFNNETILIKGARSFQFEEIVSLLEEKTHETVLEINLDAINHNLNYFKSKL
ADDVKIMVMVKAFGYGNGGLEIAKLLEHNKVNYLGVAFADEGISLKNGGIKLPIMVLNPESTSFPSIIQYKLEPEIYSIK
GLNAFLKIAREKNLKDFPIHIKVDTGMHRLGFEDNTIDELIATLKGNSTVRVQSILSHLATSDDPKHFDFVEKQISLFER
LSSKLISELNINPIRHILNTSGISNFPDAQYNMVRLGIGLYGVSNDPAEQKYLENVGTLKSIISQVRTIPAGDSVGYGRR
FMADKETKIATIPIGYADGISRLWGNQIGFVTIKNQKAYIVGSVCMDMLMVDVSHIDCKEGDSVIIFGESPTVIEMAEAL
KTIPYEIMTSISQRVKRVFFR

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=364, Percent_Identity=32.4175824175824, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI1787439, Length=366, Percent_Identity=29.5081967213115, Blast_Score=130, Evalue=5e-31,
Organism=Escherichia coli, GI1786274, Length=468, Percent_Identity=24.5726495726496, Blast_Score=121, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 92128; Mature: 91997

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSINLKSLIPVLNAEWTGSDTDIFVDHISIDSRSLQNGPQTLFIALSGANNDAHLYIAEL
CCCCHHHHHHHHCCCCCCCCCEEEEEEEECCCHHCCCCCCEEEEEEECCCCCCEEEHHHH
IEKGVQNFAVQYIPENVKGKANFFVVKNTLKALQELAAYYRDLFDFPIIGLTGSNGKTIV
HHHHHHHHEEHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHH
KEWLNFLLSPDYNIIRSPKSYNSQVGVPLSVIAINEKHNLGIFEAGISTVNEMVNLEKII
HHHHHHHCCCCCCEEECCCCCCCCCCCCEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHH
KPNIGVLTNIGSAHDEGFENLTQKINEKLLLFKKSAVIIYQKNELVDKCLLDFSAQYPLE
CCCCCEEECCCCCCHHHHHHHHHHHCHHEEEEEECEEEEEECHHHHHHHHHHCCCCCCCC
NRALFSWSFADASADVFILKKETKNDSTTIKYQYKDEIFNLEIPFSDSASIENAISCLLV
CCEEEEEEECCCCCCEEEEEECCCCCCCEEEEEEECCEEEEEECCCCCCCHHHHHHHHHH
LLHFEYDFTIIQNRMEMLYPVEMRLEVKNGIHNCSLIDDSYSSDFQSLKIALDFLESQKK
HHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCC
NASKAVILSDIFQSGFSNEELYSKVAQLISDNKINRVIGIGTTISSFQDKFPNSTMFQNT
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHCCCCCHHHHH
AAFIAEIENLNFNNETILIKGARSFQFEEIVSLLEEKTHETVLEINLDAINHNLNYFKSK
HHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEEHHHHCCHHHHHHH
LADDVKIMVMVKAFGYGNGGLEIAKLLEHNKVNYLGVAFADEGISLKNGGIKLPIMVLNP
HCCCEEEEEEEEECCCCCCCHHHHHHHHCCCCCEEEEEEECCCCEECCCCEEEEEEEECC
ESTSFPSIIQYKLEPEIYSIKGLNAFLKIAREKNLKDFPIHIKVDTGMHRLGFEDNTIDE
CCCCCCCEEEEEECCCEEEECCHHHHHHHHHHCCCCCCCEEEEECCCCEECCCCCCCHHH
LIATLKGNSTVRVQSILSHLATSDDPKHFDFVEKQISLFERLSSKLISELNINPIRHILN
HHHHHCCCCEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TSGISNFPDAQYNMVRLGIGLYGVSNDPAEQKYLENVGTLKSIISQVRTIPAGDSVGYGR
CCCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
RFMADKETKIATIPIGYADGISRLWGNQIGFVTIKNQKAYIVGSVCMDMLMVDVSHIDCK
CCCCCCCCEEEEEECCHHHHHHHHHCCCEEEEEEECCCEEEEHHHHHHHHHHHHHCCCCC
EGDSVIIFGESPTVIEMAEALKTIPYEIMTSISQRVKRVFFR
CCCEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SINLKSLIPVLNAEWTGSDTDIFVDHISIDSRSLQNGPQTLFIALSGANNDAHLYIAEL
CCCHHHHHHHHCCCCCCCCCEEEEEEEECCCHHCCCCCCEEEEEEECCCCCCEEEHHHH
IEKGVQNFAVQYIPENVKGKANFFVVKNTLKALQELAAYYRDLFDFPIIGLTGSNGKTIV
HHHHHHHHEEHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHH
KEWLNFLLSPDYNIIRSPKSYNSQVGVPLSVIAINEKHNLGIFEAGISTVNEMVNLEKII
HHHHHHHCCCCCCEEECCCCCCCCCCCCEEEEEECCCCCCCEEHHHHHHHHHHHHHHHHH
KPNIGVLTNIGSAHDEGFENLTQKINEKLLLFKKSAVIIYQKNELVDKCLLDFSAQYPLE
CCCCCEEECCCCCCHHHHHHHHHHHCHHEEEEEECEEEEEECHHHHHHHHHHCCCCCCCC
NRALFSWSFADASADVFILKKETKNDSTTIKYQYKDEIFNLEIPFSDSASIENAISCLLV
CCEEEEEEECCCCCCEEEEEECCCCCCCEEEEEEECCEEEEEECCCCCCCHHHHHHHHHH
LLHFEYDFTIIQNRMEMLYPVEMRLEVKNGIHNCSLIDDSYSSDFQSLKIALDFLESQKK
HHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCC
NASKAVILSDIFQSGFSNEELYSKVAQLISDNKINRVIGIGTTISSFQDKFPNSTMFQNT
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHCCCCCHHHHH
AAFIAEIENLNFNNETILIKGARSFQFEEIVSLLEEKTHETVLEINLDAINHNLNYFKSK
HHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEEHHHHCCHHHHHHH
LADDVKIMVMVKAFGYGNGGLEIAKLLEHNKVNYLGVAFADEGISLKNGGIKLPIMVLNP
HCCCEEEEEEEEECCCCCCCHHHHHHHHCCCCCEEEEEEECCCCEECCCCEEEEEEEECC
ESTSFPSIIQYKLEPEIYSIKGLNAFLKIAREKNLKDFPIHIKVDTGMHRLGFEDNTIDE
CCCCCCCEEEEEECCCEEEECCHHHHHHHHHHCCCCCCCEEEEECCCCEECCCCCCCHHH
LIATLKGNSTVRVQSILSHLATSDDPKHFDFVEKQISLFERLSSKLISELNINPIRHILN
HHHHHCCCCEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TSGISNFPDAQYNMVRLGIGLYGVSNDPAEQKYLENVGTLKSIISQVRTIPAGDSVGYGR
CCCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
RFMADKETKIATIPIGYADGISRLWGNQIGFVTIKNQKAYIVGSVCMDMLMVDVSHIDCK
CCCCCCCCEEEEEECCHHHHHHHHHCCCEEEEEEECCCEEEEHHHHHHHHHHHHHCCCCC
EGDSVIIFGESPTVIEMAEALKTIPYEIMTSISQRVKRVFFR
CCCEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]