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The map label for this gene is tlpA [H]

Identifier: 146299009

GI number: 146299009

Start: 1422285

End: 1423280

Strand: Direct

Name: tlpA [H]

Synonym: Fjoh_1249

Alternate gene names: 146299009

Gene position: 1422285-1423280 (Clockwise)

Preceding gene: 146298990

Following gene: 146299010

Centisome position: 23.33

GC content: 31.33

Gene sequence:

>996_bases
ATGAAAAAACTTTTTGTTACGGGTCTGTTGATTTTTAGTGCTTTGAATGTTATAGGTCAAGCCAAAAATCAAATAAAATT
TACAGCTAAAATCGATAATAGAAACAGCGATACTTTAGTTATTAAAGGAAGAAATAATTTTAAACAAGTTATTCCAATTG
ACAAAAAGGGAATTTTTGCTGCAACTTTTGAAGCTCCAAAAGGATTTTATATGTTTTCTGACGGAACTGAATCTTCAAAC
ATTTACTTAAAACCAGATTCTGAAGTTAATTTAACGATGAATGCCAAAGAATTTGATGAAACAATTGTTTATAAAGGTAA
AGGTGTAAACGAAAGTAATTTCCTTGCACAGCAATCTTTAAAAGATGAAAAATTTCAGAATGAAGCATTTGCTAAAGAAG
CAGCTGAATTTACATCGCTTTTAGAAAACAAGAAAAAAACTGATTTTGAGAATCTGGAAAAAAGTGATCTTGATCCGGAA
TTTAAAACTGCTTTAAAAATGAGTTTTGAAAGTTTTAATCAATATGCAGTTCAGGAATATGAAAGAACTGCAAATGCAAG
AAAAATGGTTGGAAAACCTTCTCCTCAATTTGATTACGAAAACTTTAAAGGAGGAAAAACAAAACTTTCAGATCTAAAAG
GAAAATACGTTTATATTGATCTTTGGGCAACCTGGTGCGCGCCTTGCAGAGCAGAGATTCCATATTTGCAAAAAATTGAA
GAAAAGTATCACGGAAAAAACATCGAGTTCGTGAGTATTTCTATTGATAAAGCAAAAGACAATGAAAAATGGAAAAAGTT
TGTGACTGATAAAAAATTAGGAGGCGTTCAGTTATTTGCAGATAAAGACTGGGAATCTGAATTCGTAGTCAATTATGGTG
TAATGGGAATTCCAAGATTTATTCTTTTAGACCCAAATGGCAACATTGTAAGTTCTGATGCTACAAGACCCTCTGATCCA
AAGCTTCAGGATCAGTTAAACACTTTATTGAACTAA

Upstream 100 bases:

>100_bases
GTAAACTTGATACGTATAATTTTAAATATTTTGTTAATTCTGAAATTTCGAAGCTGTTATTTCTTTAGATTTGAATCACT
AAAAACAAACTTTAAATAGT

Downstream 100 bases:

>100_bases
TTTATTTACGAAATTTATAACGTTATCGTAATTTTAGTTTTTAACTAAAATACCAGTAAAACCAGTGCCTGAGCGCTGGT
TTTTTTGTTTTTAGGAAATT

Product: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: NA

Alternate protein names: Cytochrome c biogenesis protein tlpA [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MKKLFVTGLLIFSALNVIGQAKNQIKFTAKIDNRNSDTLVIKGRNNFKQVIPIDKKGIFAATFEAPKGFYMFSDGTESSN
IYLKPDSEVNLTMNAKEFDETIVYKGKGVNESNFLAQQSLKDEKFQNEAFAKEAAEFTSLLENKKKTDFENLEKSDLDPE
FKTALKMSFESFNQYAVQEYERTANARKMVGKPSPQFDYENFKGGKTKLSDLKGKYVYIDLWATWCAPCRAEIPYLQKIE
EKYHGKNIEFVSISIDKAKDNEKWKKFVTDKKLGGVQLFADKDWESEFVVNYGVMGIPRFILLDPNGNIVSSDATRPSDP
KLQDQLNTLLN

Sequences:

>Translated_331_residues
MKKLFVTGLLIFSALNVIGQAKNQIKFTAKIDNRNSDTLVIKGRNNFKQVIPIDKKGIFAATFEAPKGFYMFSDGTESSN
IYLKPDSEVNLTMNAKEFDETIVYKGKGVNESNFLAQQSLKDEKFQNEAFAKEAAEFTSLLENKKKTDFENLEKSDLDPE
FKTALKMSFESFNQYAVQEYERTANARKMVGKPSPQFDYENFKGGKTKLSDLKGKYVYIDLWATWCAPCRAEIPYLQKIE
EKYHGKNIEFVSISIDKAKDNEKWKKFVTDKKLGGVQLFADKDWESEFVVNYGVMGIPRFILLDPNGNIVSSDATRPSDP
KLQDQLNTLLN
>Mature_331_residues
MKKLFVTGLLIFSALNVIGQAKNQIKFTAKIDNRNSDTLVIKGRNNFKQVIPIDKKGIFAATFEAPKGFYMFSDGTESSN
IYLKPDSEVNLTMNAKEFDETIVYKGKGVNESNFLAQQSLKDEKFQNEAFAKEAAEFTSLLENKKKTDFENLEKSDLDPE
FKTALKMSFESFNQYAVQEYERTANARKMVGKPSPQFDYENFKGGKTKLSDLKGKYVYIDLWATWCAPCRAEIPYLQKIE
EKYHGKNIEFVSISIDKAKDNEKWKKFVTDKKLGGVQLFADKDWESEFVVNYGVMGIPRFILLDPNGNIVSSDATRPSDP
KLQDQLNTLLN

Specific function: Involved in cytochrome aa3 assembly [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 37754; Mature: 37754

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLFVTGLLIFSALNVIGQAKNQIKFTAKIDNRNSDTLVIKGRNNFKQVIPIDKKGIFA
CCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEECCCCCCEECCCCCCCEEE
ATFEAPKGFYMFSDGTESSNIYLKPDSEVNLTMNAKEFDETIVYKGKGVNESNFLAQQSL
EEECCCCCEEEEECCCCCCEEEECCCCCEEEEECHHHHCCEEEEECCCCCHHHHHHHHHH
KDEKFQNEAFAKEAAEFTSLLENKKKTDFENLEKSDLDPEFKTALKMSFESFNQYAVQEY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ERTANARKMVGKPSPQFDYENFKGGKTKLSDLKGKYVYIDLWATWCAPCRAEIPYLQKIE
HHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCEEEEEEEHHHCCCCCCCCHHHHHHH
EKYHGKNIEFVSISIDKAKDNEKWKKFVTDKKLGGVQLFADKDWESEFVVNYGVMGIPRF
HHHCCCCEEEEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCCCCCCEE
ILLDPNGNIVSSDATRPSDPKLQDQLNTLLN
EEECCCCCEEECCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MKKLFVTGLLIFSALNVIGQAKNQIKFTAKIDNRNSDTLVIKGRNNFKQVIPIDKKGIFA
CCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEECCCCCCEECCCCCCCEEE
ATFEAPKGFYMFSDGTESSNIYLKPDSEVNLTMNAKEFDETIVYKGKGVNESNFLAQQSL
EEECCCCCEEEEECCCCCCEEEECCCCCEEEEECHHHHCCEEEEECCCCCHHHHHHHHHH
KDEKFQNEAFAKEAAEFTSLLENKKKTDFENLEKSDLDPEFKTALKMSFESFNQYAVQEY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ERTANARKMVGKPSPQFDYENFKGGKTKLSDLKGKYVYIDLWATWCAPCRAEIPYLQKIE
HHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCEEEEEEEHHHCCCCCCCCHHHHHHH
EKYHGKNIEFVSISIDKAKDNEKWKKFVTDKKLGGVQLFADKDWESEFVVNYGVMGIPRF
HHHCCCCEEEEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCCCCCCEE
ILLDPNGNIVSSDATRPSDPKLQDQLNTLLN
EEECCCCCEEECCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8253065; 12597275 [H]