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The map label for this gene is namA [H]

Identifier: 146298926

GI number: 146298926

Start: 1315618

End: 1316688

Strand: Direct

Name: namA [H]

Synonym: Fjoh_1165

Alternate gene names: 146298926

Gene position: 1315618-1316688 (Clockwise)

Preceding gene: 146298925

Following gene: 146298927

Centisome position: 21.58

GC content: 40.9

Gene sequence:

>1071_bases
ATGGCTTCACAATTATTTTCTCCCTTAACTTTAAAAAGCATCACCTTAAAAAATAGAATCGTTATTTCGCCAATGTGCCA
ATATTCAGCCGTTGACGGATTTGCAAACGACTGGCATCTGGTTCACTTAGGAAGCCGTGCAAGCGGTGGCGTTGGTTTAA
TTATTCAGGAAGCGACTGCCGTTTCTCCCGAAGCCAGAATTTCTCCTTCAGACCTTGGGATCTGGAAAGACGAACATATC
GAAAAACTCAAACAAATCAATGCTTTTATTGTTTCTCAAAATTCAGTTCCCGGAATCCAGCTGGCACATGCCGGAAGAAA
AGCAAGTGTTTCGGCTCCGTGGCTCGGAAATAAAAAATTAGATTTTGCTCAGGGCGGATGGCAGACAGTTGCACCAAGTG
CGGTTCCGTATCACGAAGGAGAACCTTTTCTTCCCGAAGCTTTAGACCAAAACGGAATCCAAAAAATAATCTCCGATTTT
AAAGCAGCAACAAAAAGAGCCGTTGAAGCCGGATACAAAGTGTTAGAAATTCACGGTGCGCACGGTTATTTACTGCACCA
GTTTTTATCGCCTTTAACAAATATCAGAACCGACGAATATGGCGGAAGTTTCGAAAACCGAATCCGTTTTACACTCGAAA
TTGTAGAAGCAGTTCAAACCGAATGGCCTTCAGATTTACCTTTAATTGTTAGAATTTCAGCAACAGACTGGGCAGAAGGC
GGGTGGAATCCTGAAGAATCTGTACAGCTTTCGAAAATTCTAAAAGAAAAAGGAGTAGATTTAATCGATGTTTCGTCTGG
CGGATTAGTTTCACATCAAAAAATTGCAATTGGTCCGGGTTATCAGGTTCCTTTTGCAGAAAAAATCAAGAAAGAAGCCA
ATATTCTTACAGGCGCTGTAGGTTTGATTACCGAAGCGAAACAAGCCGAGGAAATTTTAAATAAAGGTCAGGCCGATTTA
ATCTTGTTTGCCAGAGAATCACTTAGAAATCCTAACCTGCCATTAGATTTCGCCAAAGAGTTAAACGACGATATTCAATG
GCCAAAACAATACGAAAGAGCTAAAATTTAA

Upstream 100 bases:

>100_bases
AAACATTTCAATTTCTCGTTTTAGCAAGATGCCGTAACTTTACTTTTTATAAAGGCTACTATTTTTAATTGGCAGCACTA
ATCTATTAAAAGTTACAAGT

Downstream 100 bases:

>100_bases
ATTTTTATTGGCCGCAGATTGCACAGATTAAAGTGATTTTATTTAGTTTTATTTGCCACAAATTTCACTAATTTGCACAA
ATCGGTACGTTTAAAAAGGC

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MASQLFSPLTLKSITLKNRIVISPMCQYSAVDGFANDWHLVHLGSRASGGVGLIIQEATAVSPEARISPSDLGIWKDEHI
EKLKQINAFIVSQNSVPGIQLAHAGRKASVSAPWLGNKKLDFAQGGWQTVAPSAVPYHEGEPFLPEALDQNGIQKIISDF
KAATKRAVEAGYKVLEIHGAHGYLLHQFLSPLTNIRTDEYGGSFENRIRFTLEIVEAVQTEWPSDLPLIVRISATDWAEG
GWNPEESVQLSKILKEKGVDLIDVSSGGLVSHQKIAIGPGYQVPFAEKIKKEANILTGAVGLITEAKQAEEILNKGQADL
ILFARESLRNPNLPLDFAKELNDDIQWPKQYERAKI

Sequences:

>Translated_356_residues
MASQLFSPLTLKSITLKNRIVISPMCQYSAVDGFANDWHLVHLGSRASGGVGLIIQEATAVSPEARISPSDLGIWKDEHI
EKLKQINAFIVSQNSVPGIQLAHAGRKASVSAPWLGNKKLDFAQGGWQTVAPSAVPYHEGEPFLPEALDQNGIQKIISDF
KAATKRAVEAGYKVLEIHGAHGYLLHQFLSPLTNIRTDEYGGSFENRIRFTLEIVEAVQTEWPSDLPLIVRISATDWAEG
GWNPEESVQLSKILKEKGVDLIDVSSGGLVSHQKIAIGPGYQVPFAEKIKKEANILTGAVGLITEAKQAEEILNKGQADL
ILFARESLRNPNLPLDFAKELNDDIQWPKQYERAKI
>Mature_355_residues
ASQLFSPLTLKSITLKNRIVISPMCQYSAVDGFANDWHLVHLGSRASGGVGLIIQEATAVSPEARISPSDLGIWKDEHIE
KLKQINAFIVSQNSVPGIQLAHAGRKASVSAPWLGNKKLDFAQGGWQTVAPSAVPYHEGEPFLPEALDQNGIQKIISDFK
AATKRAVEAGYKVLEIHGAHGYLLHQFLSPLTNIRTDEYGGSFENRIRFTLEIVEAVQTEWPSDLPLIVRISATDWAEGG
WNPEESVQLSKILKEKGVDLIDVSSGGLVSHQKIAIGPGYQVPFAEKIKKEANILTGAVGLITEAKQAEEILNKGQADLI
LFARESLRNPNLPLDFAKELNDDIQWPKQYERAKI

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=349, Percent_Identity=32.9512893982808, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1789463, Length=338, Percent_Identity=27.5147928994083, Blast_Score=119, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17559802, Length=254, Percent_Identity=31.8897637795276, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17540738, Length=359, Percent_Identity=28.9693593314763, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI72001454, Length=267, Percent_Identity=29.9625468164794, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17559804, Length=230, Percent_Identity=29.5652173913043, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17564188, Length=229, Percent_Identity=27.5109170305677, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17565138, Length=312, Percent_Identity=25.6410256410256, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17566914, Length=306, Percent_Identity=27.7777777777778, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6325086, Length=261, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6321973, Length=220, Percent_Identity=33.1818181818182, Blast_Score=102, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 39084; Mature: 38953

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASQLFSPLTLKSITLKNRIVISPMCQYSAVDGFANDWHLVHLGSRASGGVGLIIQEATA
CCCHHCCCCCEEEEEECCEEEECCCHHHHHCCCCCCCEEEEEECCCCCCCEEEEEECCCC
VSPEARISPSDLGIWKDEHIEKLKQINAFIVSQNSVPGIQLAHAGRKASVSAPWLGNKKL
CCCCCCCCHHHCCCCCHHHHHHHHHHHEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCC
DFAQGGWQTVAPSAVPYHEGEPFLPEALDQNGIQKIISDFKAATKRAVEAGYKVLEIHGA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
HGYLLHQFLSPLTNIRTDEYGGSFENRIRFTLEIVEAVQTEWPSDLPLIVRISATDWAEG
CHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCC
GWNPEESVQLSKILKEKGVDLIDVSSGGLVSHQKIAIGPGYQVPFAEKIKKEANILTGAV
CCCHHHHHHHHHHHHHCCCCEEEECCCCCEECCEEEECCCCCCCHHHHHHHHHHHHHHHH
GLITEAKQAEEILNKGQADLILFARESLRNPNLPLDFAKELNDDIQWPKQYERAKI
HHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCCCCHHHHHHCCCCCCCCHHHHHCCC
>Mature Secondary Structure 
ASQLFSPLTLKSITLKNRIVISPMCQYSAVDGFANDWHLVHLGSRASGGVGLIIQEATA
CCHHCCCCCEEEEEECCEEEECCCHHHHHCCCCCCCEEEEEECCCCCCCEEEEEECCCC
VSPEARISPSDLGIWKDEHIEKLKQINAFIVSQNSVPGIQLAHAGRKASVSAPWLGNKKL
CCCCCCCCHHHCCCCCHHHHHHHHHHHEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCC
DFAQGGWQTVAPSAVPYHEGEPFLPEALDQNGIQKIISDFKAATKRAVEAGYKVLEIHGA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
HGYLLHQFLSPLTNIRTDEYGGSFENRIRFTLEIVEAVQTEWPSDLPLIVRISATDWAEG
CHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCC
GWNPEESVQLSKILKEKGVDLIDVSSGGLVSHQKIAIGPGYQVPFAEKIKKEANILTGAV
CCCHHHHHHHHHHHHHCCCCEEEECCCCCEECCEEEECCCCCCCHHHHHHHHHHHHHHHH
GLITEAKQAEEILNKGQADLILFARESLRNPNLPLDFAKELNDDIQWPKQYERAKI
HHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCCCCHHHHHHCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA