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The map label for this gene is ribF [H]

Identifier: 146298561

GI number: 146298561

Start: 892273

End: 893205

Strand: Direct

Name: ribF [H]

Synonym: Fjoh_0799

Alternate gene names: 146298561

Gene position: 892273-893205 (Clockwise)

Preceding gene: 146298559

Following gene: 146298562

Centisome position: 14.63

GC content: 31.51

Gene sequence:

>933_bases
TTGAAGCTCTTTCATTCTATAAACGATTTCCATACGACCAAGAAAACAATTTTAACTCTTGGAACTTTTGACGGCGTACA
TATTGGTCATAAAAAAATTCTGGAAAGAATTACTGAAAATACCGAAAATGGAAAGTATGAAAGTTTAGTGCTTACTTTTT
TTCCGCATCCAAGAATGGTTCTGCAGGAAAAATCAGAAATAAAACTTCTAAATACAATTTCTGAAAAAACAAAACTTTTA
GAAGCAACCGGAATTGAAAATCTGGTTATACATCCGTTCAACGAAAGTTTTTCAAGACTTACTGCCGAAGAATTTGTGCA
CTCTATTTTAGTAGATCAATTTCATATTCAAAAAATAATTATTGGACACGATCATCGTTTTGGAAGAAACAGAACAGCAA
ATATTGAGAATTTAATTGCTTTTGGAATTGAATACGGTTTTGAAGTCGAACAAATATCAGCCGAGGAAATTCAGGATGTT
TCAGTAAGTTCAACTAAAATTAGAAAAGCTCTTACTGAAGGAAATATGATTTTGGCCAATGAATATTTGGGATATGACTA
TTTCTTAACTGGCGAAGTTGTTCAAGGAAAGCAATTAGGAAGAACAATTGGCTTTCCTACTGCTAACATACAAATTGAAG
AAGAATACAAATTGATTCCTAAAAACGGAGTTTATGTAGTTCGCGCTTTAATTGATGAAAAGGAAGTTTTTGGAATGATG
AATATTGGTTTTAATCCAACTGTTAATGGACAAAAACAAACTATAGAAGTCAATCTTTTTGATTTCGATGCCGATATTTA
TGGTAAAAAAATCGAAGTTTCGTTACTTCAATATCTTCGTGACGAACAAAAATTCGGCTCTATTGATTTATTAAAAGCCC
AATTAAATCAAGACAAACAAAATGCTTTGGCCTTTGTGAGCAAACTTCAATAA

Upstream 100 bases:

>100_bases
TTTTCGGCAAAAGAAAGCGAATCTTCTTAAAAAATCAATTCAGCGAAGCACAAAATTTAAAATAGATAGTATAAATTTGC
AGCATCTTAAATAATTTGTT

Downstream 100 bases:

>100_bases
AATTTCAAAAAACACTTTTAACTCTTTTTAGATCATCGTAGTTATTTTTTTAGTAAATTTGATATAGAACTGTTTTTCAA
ATATTTACTATTAACTTCTT

Product: riboflavin biosynthesis protein RibF

Products: NA

Alternate protein names: Riboflavin kinase; Flavokinase; FMN adenylyltransferase; FAD pyrophosphorylase; FAD synthase [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MKLFHSINDFHTTKKTILTLGTFDGVHIGHKKILERITENTENGKYESLVLTFFPHPRMVLQEKSEIKLLNTISEKTKLL
EATGIENLVIHPFNESFSRLTAEEFVHSILVDQFHIQKIIIGHDHRFGRNRTANIENLIAFGIEYGFEVEQISAEEIQDV
SVSSTKIRKALTEGNMILANEYLGYDYFLTGEVVQGKQLGRTIGFPTANIQIEEEYKLIPKNGVYVVRALIDEKEVFGMM
NIGFNPTVNGQKQTIEVNLFDFDADIYGKKIEVSLLQYLRDEQKFGSIDLLKAQLNQDKQNALAFVSKLQ

Sequences:

>Translated_310_residues
MKLFHSINDFHTTKKTILTLGTFDGVHIGHKKILERITENTENGKYESLVLTFFPHPRMVLQEKSEIKLLNTISEKTKLL
EATGIENLVIHPFNESFSRLTAEEFVHSILVDQFHIQKIIIGHDHRFGRNRTANIENLIAFGIEYGFEVEQISAEEIQDV
SVSSTKIRKALTEGNMILANEYLGYDYFLTGEVVQGKQLGRTIGFPTANIQIEEEYKLIPKNGVYVVRALIDEKEVFGMM
NIGFNPTVNGQKQTIEVNLFDFDADIYGKKIEVSLLQYLRDEQKFGSIDLLKAQLNQDKQNALAFVSKLQ
>Mature_310_residues
MKLFHSINDFHTTKKTILTLGTFDGVHIGHKKILERITENTENGKYESLVLTFFPHPRMVLQEKSEIKLLNTISEKTKLL
EATGIENLVIHPFNESFSRLTAEEFVHSILVDQFHIQKIIIGHDHRFGRNRTANIENLIAFGIEYGFEVEQISAEEIQDV
SVSSTKIRKALTEGNMILANEYLGYDYFLTGEVVQGKQLGRTIGFPTANIQIEEEYKLIPKNGVYVVRALIDEKEVFGMM
NIGFNPTVNGQKQTIEVNLFDFDADIYGKKIEVSLLQYLRDEQKFGSIDLLKAQLNQDKQNALAFVSKLQ

Specific function: Unknown

COG id: COG0196

COG function: function code H; FAD synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribF family [H]

Homologues:

Organism=Escherichia coli, GI1786208, Length=308, Percent_Identity=36.3636363636364, Blast_Score=211, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI17541882, Length=117, Percent_Identity=34.1880341880342, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24644927, Length=125, Percent_Identity=34.4, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015864
- InterPro:   IPR015865
- InterPro:   IPR002606
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06574 FAD_syn; PF01687 Flavokinase [H]

EC number: =2.7.1.26; =2.7.7.2 [H]

Molecular weight: Translated: 35400; Mature: 35400

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFHSINDFHTTKKTILTLGTFDGVHIGHKKILERITENTENGKYESLVLTFFPHPRMV
CCCHHCHHHHHCCCEEEEEEECCCCEECCHHHHHHHHHCCCCCCCEEEEEEEECCCCCHH
LQEKSEIKLLNTISEKTKLLEATGIENLVIHPFNESFSRLTAEEFVHSILVDQFHIQKII
HCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHEEEEE
IGHDHRFGRNRTANIENLIAFGIEYGFEVEQISAEEIQDVSVSSTKIRKALTEGNMILAN
EECCCCCCCCCCCCHHHHHHHHHHCCCCHHHCCHHHHHCCCCCHHHHHHHHHCCCEEEEE
EYLGYDYFLTGEVVQGKQLGRTIGFPTANIQIEEEYKLIPKNGVYVVRALIDEKEVFGMM
CCCCEEEEEECCEECCHHHCCCCCCCCCEEEECCCEEECCCCCEEEEEEHHCHHHHEEEE
NIGFNPTVNGQKQTIEVNLFDFDADIYGKKIEVSLLQYLRDEQKFGSIDLLKAQLNQDKQ
ECCCCCCCCCCCEEEEEEEEEECCCCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHCCCHH
NALAFVSKLQ
HHHHHHHHCC
>Mature Secondary Structure
MKLFHSINDFHTTKKTILTLGTFDGVHIGHKKILERITENTENGKYESLVLTFFPHPRMV
CCCHHCHHHHHCCCEEEEEEECCCCEECCHHHHHHHHHCCCCCCCEEEEEEEECCCCCHH
LQEKSEIKLLNTISEKTKLLEATGIENLVIHPFNESFSRLTAEEFVHSILVDQFHIQKII
HCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHEEEEE
IGHDHRFGRNRTANIENLIAFGIEYGFEVEQISAEEIQDVSVSSTKIRKALTEGNMILAN
EECCCCCCCCCCCCHHHHHHHHHHCCCCHHHCCHHHHHCCCCCHHHHHHHHHCCCEEEEE
EYLGYDYFLTGEVVQGKQLGRTIGFPTANIQIEEEYKLIPKNGVYVVRALIDEKEVFGMM
CCCCEEEEEECCEECCHHHCCCCCCCCCEEEECCCEEECCCCCEEEEEEHHCHHHHEEEE
NIGFNPTVNGQKQTIEVNLFDFDADIYGKKIEVSLLQYLRDEQKFGSIDLLKAQLNQDKQ
ECCCCCCCCCCCEEEEEEEEEECCCCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHCCCHH
NALAFVSKLQ
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]