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The map label for this gene is zraS [C]

Identifier: 146284495

GI number: 146284495

Start: 4537784

End: 4540189

Strand: Direct

Name: zraS [C]

Synonym: PST_4184

Alternate gene names: 146284495

Gene position: 4537784-4540189 (Clockwise)

Preceding gene: 146284494

Following gene: 146284496

Centisome position: 99.35

GC content: 66.33

Gene sequence:

>2406_bases
ATGCCAGCGTCAAAGAACATCAGTGTCCTGTTCATCGAGGACAGCCGGCATGATGCCGAACTGGCCCAGCTGGCGCTGGA
GCGCAGTGGCTACACCTTGCAGACGGAGCTGGTCTACAACCACGCCGGGGTGGTCGAAGCGTTACAGCGACGCCGCTTCG
ATCTGATCCTGGCGGATTTCATCCTGCCCGGTTTCTCCGGCAGCCAGGCGCTGCAGGAGGCCCGAAGGCTCGCCCCGCAG
ACCCCCTTCATTTTCCTTTCCGGCGTATTCGGCGAAGAGCACGCGGTAAACATGATGCGCTCCGGCGCCGTCGACTACGT
GCTAAAGCAGAACCTCGGCTTTCTGCCCAAGGCCGTGGAACGAGCGTTGGGCGAGGTCAACGAGCGCCGCCGGCGCCTGC
AGGCCGAACAGGCGCTGCGCGAGGTGGAAGTGCGCGCGCGCCTGGCGATCGATGCCGCGCGGCTGGGCATGTGGGACTAC
GAGCCGCAGAGCGGCACCCTGATCTGGGACGAACGCTGTCGCAGCATGCTCGGCCTCGATACGGAGGCGCCGGTGAGCAT
GGGGCTGTTCGAGCAACTCCTGCACCCCGAGGATCGCGAGCGGATTCACGACGAAGTGATCCGCGCCATCTCCGGCGAGG
ATGCCGGCGAGTTCTGCACCTGTTATCGCGTGGTGTTCGGCGACGGCAGCATTCGCTGGATGGAGACCCGCGGCCAGGCC
TTCTTCGAGAGCGGTCAGTGCACGCGCTTCGTCGGTGTGGTCATGGACATCACCGAGCAGCAGCTGACTACCCAGAGTCT
GCGACAGATCAACGAAACCCTGGGCGAGCGGGTCGAGGAGCGCACCCGCGAACGCGACCGGACCTGGGAGCTCTCCCGCG
ACCTGCTCGCCGTCACCGAGCTGGACATGCTGCCGGTGGCGCTCAATCCGTTCTGGGAGAACGCGCTCGGCTGGTCATAC
AGCGAACTGATGCAACGGCCTTTGACCCAGCTGGTGCATCCCGACGATCTGCAGGCGACGCTGGAAGAGAACGCCAATGT
CGGCCGCGGCAAGGTCACCAACCGCTTCGTCAACCGCATGCGCCACCGCGACGGCAGCTACCGCTGGCTGTCGTGGTCGG
CCGTGGCCGATGGCGGACGCATCTATTCGGCGGCGCGTGACATCACCAGCGAAATCGCCGCGGTGGACAAGCTGGCCGAG
GCCAACCGCGAGCTGCGTGCGCAGATTCAGGAGCGCGAGCGGGTCGAAGCCACCCTGCAGCAGATGCAGCGCCTGGAAGC
GGTGGGTCAGCTGACCGCCGGGGTCGCCCACGATTTCAACAACCTGCTCACCGTCATTCTCACCAGTGCCAGCTTCCTGA
AGAACGATCTGGAGCAGGGCGCACCGCTTGAACGCAGCCTGCGTCGATTGCAGTACATCCGCGAGTCCGGCGAACGCGGC
GCCACCCTCACCGGCCAGCTGCTTGCCTTCGCCCGCCGCCAGCAGCTGGCACCCACCGCCATCGACCTCAACGACACCCT
GGTCAGCCTGCTCAGCCTGCTGAAGAGCACGCTCGGCGGCAGCGTCAGCATCGAGACCGATACCCAGGCGGACATCTGGC
ATGCGCTGGTCGACCCGACCCAGATCGAGATGATCATTCTCAACCTGGCGATCAACGCCCGCGATGCCATGGGCGACGGT
GGCCGGCTGACGCTGGGTACGCGCAACGTGGTGGTCACCGAGCCGGCGCTGCGGGCTGAAGATCCGGCGCCGGGCGAGTA
CGTGGTGCTCTCGGTCACCGACACCGGTACCGGCATGAGCGAGGAAGTGCTGAGCAAGGCGTTCGAACCTTTCTTCACCA
CCAAGGAAGTCGGCAAGGGCTCCGGCCTCGGCCTGGCGCAGGTGTTCGGCTTCGCCAAGCAGTCCGGTGGCGGCGCGCGC
ATCGAAAGCCGTGTGGGGGTCGGCACCACCGTGAAGGTGTTCCTGCCACGCACCGCGGCGCCGGAGCAGCCGGAACAGGC
CACGGCGCTGAGTGCGGGCAGCCACGACGAGAACAGCCAACACCGCATCCTGCTGGTGGACGATGACCACAGCGTGCGCG
AGGTGACGGCGCAGATGCTGGAAAACCTCGGCTTCGCCGTCACCGAGGCGGAAAGCGGCGACCATGCGCTGCAGCTGCTC
CGCGACGGAGCGGCGGTGGACCTGCTGCTGGCGGATTTCGCCATGCCGGGGATGAACGGCGGTGAACTGGCCCGCGCGGT
GCGCGTTCGCCGCCCGCAGCTGCCGGTGGTTTTCGTCACCGGCTATGCCGAGCTCTGCGAGCTTGGCCTGGACGGCTATT
CGATCATCCAGAAGCCGTTTCGCGAGGAACAGCTGGCCAACAAGATCCACCTCGCGCTGCGCGAAGGCAGCCTGGCCGAT
GGCTGA

Upstream 100 bases:

>100_bases
CAAGCGTGCGCGCAACAAAGAAGAAAAGAGCTCATAACGAAACGGTCCGCCTTGCCTGGCGGACCGTTTCGACGATCCCT
GCTCCCTCGACAGGACGGAT

Downstream 100 bases:

>100_bases
ATTGCGCATGCGCCTGCGGCAGGCTACGGCGCCGCTGCACGATCGGGTCGACAGCGCCTTCTCGGGCTTCGATCTGCAGG
ACCCGGACGATTACCGCCGC

Product: sensory box histidine kinase/response regulator

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 801; Mature: 800

Protein sequence:

>801_residues
MPASKNISVLFIEDSRHDAELAQLALERSGYTLQTELVYNHAGVVEALQRRRFDLILADFILPGFSGSQALQEARRLAPQ
TPFIFLSGVFGEEHAVNMMRSGAVDYVLKQNLGFLPKAVERALGEVNERRRRLQAEQALREVEVRARLAIDAARLGMWDY
EPQSGTLIWDERCRSMLGLDTEAPVSMGLFEQLLHPEDRERIHDEVIRAISGEDAGEFCTCYRVVFGDGSIRWMETRGQA
FFESGQCTRFVGVVMDITEQQLTTQSLRQINETLGERVEERTRERDRTWELSRDLLAVTELDMLPVALNPFWENALGWSY
SELMQRPLTQLVHPDDLQATLEENANVGRGKVTNRFVNRMRHRDGSYRWLSWSAVADGGRIYSAARDITSEIAAVDKLAE
ANRELRAQIQERERVEATLQQMQRLEAVGQLTAGVAHDFNNLLTVILTSASFLKNDLEQGAPLERSLRRLQYIRESGERG
ATLTGQLLAFARRQQLAPTAIDLNDTLVSLLSLLKSTLGGSVSIETDTQADIWHALVDPTQIEMIILNLAINARDAMGDG
GRLTLGTRNVVVTEPALRAEDPAPGEYVVLSVTDTGTGMSEEVLSKAFEPFFTTKEVGKGSGLGLAQVFGFAKQSGGGAR
IESRVGVGTTVKVFLPRTAAPEQPEQATALSAGSHDENSQHRILLVDDDHSVREVTAQMLENLGFAVTEAESGDHALQLL
RDGAAVDLLLADFAMPGMNGGELARAVRVRRPQLPVVFVTGYAELCELGLDGYSIIQKPFREEQLANKIHLALREGSLAD
G

Sequences:

>Translated_801_residues
MPASKNISVLFIEDSRHDAELAQLALERSGYTLQTELVYNHAGVVEALQRRRFDLILADFILPGFSGSQALQEARRLAPQ
TPFIFLSGVFGEEHAVNMMRSGAVDYVLKQNLGFLPKAVERALGEVNERRRRLQAEQALREVEVRARLAIDAARLGMWDY
EPQSGTLIWDERCRSMLGLDTEAPVSMGLFEQLLHPEDRERIHDEVIRAISGEDAGEFCTCYRVVFGDGSIRWMETRGQA
FFESGQCTRFVGVVMDITEQQLTTQSLRQINETLGERVEERTRERDRTWELSRDLLAVTELDMLPVALNPFWENALGWSY
SELMQRPLTQLVHPDDLQATLEENANVGRGKVTNRFVNRMRHRDGSYRWLSWSAVADGGRIYSAARDITSEIAAVDKLAE
ANRELRAQIQERERVEATLQQMQRLEAVGQLTAGVAHDFNNLLTVILTSASFLKNDLEQGAPLERSLRRLQYIRESGERG
ATLTGQLLAFARRQQLAPTAIDLNDTLVSLLSLLKSTLGGSVSIETDTQADIWHALVDPTQIEMIILNLAINARDAMGDG
GRLTLGTRNVVVTEPALRAEDPAPGEYVVLSVTDTGTGMSEEVLSKAFEPFFTTKEVGKGSGLGLAQVFGFAKQSGGGAR
IESRVGVGTTVKVFLPRTAAPEQPEQATALSAGSHDENSQHRILLVDDDHSVREVTAQMLENLGFAVTEAESGDHALQLL
RDGAAVDLLLADFAMPGMNGGELARAVRVRRPQLPVVFVTGYAELCELGLDGYSIIQKPFREEQLANKIHLALREGSLAD
G
>Mature_800_residues
PASKNISVLFIEDSRHDAELAQLALERSGYTLQTELVYNHAGVVEALQRRRFDLILADFILPGFSGSQALQEARRLAPQT
PFIFLSGVFGEEHAVNMMRSGAVDYVLKQNLGFLPKAVERALGEVNERRRRLQAEQALREVEVRARLAIDAARLGMWDYE
PQSGTLIWDERCRSMLGLDTEAPVSMGLFEQLLHPEDRERIHDEVIRAISGEDAGEFCTCYRVVFGDGSIRWMETRGQAF
FESGQCTRFVGVVMDITEQQLTTQSLRQINETLGERVEERTRERDRTWELSRDLLAVTELDMLPVALNPFWENALGWSYS
ELMQRPLTQLVHPDDLQATLEENANVGRGKVTNRFVNRMRHRDGSYRWLSWSAVADGGRIYSAARDITSEIAAVDKLAEA
NRELRAQIQERERVEATLQQMQRLEAVGQLTAGVAHDFNNLLTVILTSASFLKNDLEQGAPLERSLRRLQYIRESGERGA
TLTGQLLAFARRQQLAPTAIDLNDTLVSLLSLLKSTLGGSVSIETDTQADIWHALVDPTQIEMIILNLAINARDAMGDGG
RLTLGTRNVVVTEPALRAEDPAPGEYVVLSVTDTGTGMSEEVLSKAFEPFFTTKEVGKGSGLGLAQVFGFAKQSGGGARI
ESRVGVGTTVKVFLPRTAAPEQPEQATALSAGSHDENSQHRILLVDDDHSVREVTAQMLENLGFAVTEAESGDHALQLLR
DGAAVDLLLADFAMPGMNGGELARAVRVRRPQLPVVFVTGYAELCELGLDGYSIIQKPFREEQLANKIHLALREGSLADG

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=265, Percent_Identity=29.811320754717, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI87081816, Length=406, Percent_Identity=24.8768472906404, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1788549, Length=246, Percent_Identity=26.8292682926829, Blast_Score=76, Evalue=9e-15,
Organism=Escherichia coli, GI1788713, Length=373, Percent_Identity=24.9329758713137, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI48994928, Length=309, Percent_Identity=26.537216828479, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788381, Length=213, Percent_Identity=27.2300469483568, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 88705; Mature: 88573

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPASKNISVLFIEDSRHDAELAQLALERSGYTLQTELVYNHAGVVEALQRRRFDLILADF
CCCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
ILPGFSGSQALQEARRLAPQTPFIFLSGVFGEEHAVNMMRSGAVDYVLKQNLGFLPKAVE
HCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCHHHHHHHCCCCCHHHHH
RALGEVNERRRRLQAEQALREVEVRARLAIDAARLGMWDYEPQSGTLIWDERCRSMLGLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHCCC
TEAPVSMGLFEQLLHPEDRERIHDEVIRAISGEDAGEFCTCYRVVFGDGSIRWMETRGQA
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHEEEEEEECCCCEEEEECCCCH
FFESGQCTRFVGVVMDITEQQLTTQSLRQINETLGERVEERTRERDRTWELSRDLLAVTE
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDMLPVALNPFWENALGWSYSELMQRPLTQLVHPDDLQATLEENANVGRGKVTNRFVNRM
HHHCCEECCHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHH
RHRDGSYRWLSWSAVADGGRIYSAARDITSEIAAVDKLAEANRELRAQIQERERVEATLQ
HCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QMQRLEAVGQLTAGVAHDFNNLLTVILTSASFLKNDLEQGAPLERSLRRLQYIRESGERG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC
ATLTGQLLAFARRQQLAPTAIDLNDTLVSLLSLLKSTLGGSVSIETDTQADIWHALVDPT
CCHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHCCCC
QIEMIILNLAINARDAMGDGGRLTLGTRNVVVTEPALRAEDPAPGEYVVLSVTDTGTGMS
CEEEEEEEEEEECCCCCCCCCEEEEECCCEEEECCCCCCCCCCCCCEEEEEEECCCCCCH
EEVLSKAFEPFFTTKEVGKGSGLGLAQVFGFAKQSGGGARIESRVGVGTTVKVFLPRTAA
HHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHCCCCCCEEECCCCCCCEEEEEEECCCC
PEQPEQATALSAGSHDENSQHRILLVDDDHSVREVTAQMLENLGFAVTEAESGDHALQLL
CCCCCHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEECCCCHHHHHHH
RDGAAVDLLLADFAMPGMNGGELARAVRVRRPQLPVVFVTGYAELCELGLDGYSIIQKPF
HCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEECCHHHHHHHCCCCHHHHHHHH
REEQLANKIHLALREGSLADG
HHHHHHHHHHHHEECCCCCCC
>Mature Secondary Structure 
PASKNISVLFIEDSRHDAELAQLALERSGYTLQTELVYNHAGVVEALQRRRFDLILADF
CCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
ILPGFSGSQALQEARRLAPQTPFIFLSGVFGEEHAVNMMRSGAVDYVLKQNLGFLPKAVE
HCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCHHHHHHHCCCCCHHHHH
RALGEVNERRRRLQAEQALREVEVRARLAIDAARLGMWDYEPQSGTLIWDERCRSMLGLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHCCC
TEAPVSMGLFEQLLHPEDRERIHDEVIRAISGEDAGEFCTCYRVVFGDGSIRWMETRGQA
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHEEEEEEECCCCEEEEECCCCH
FFESGQCTRFVGVVMDITEQQLTTQSLRQINETLGERVEERTRERDRTWELSRDLLAVTE
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDMLPVALNPFWENALGWSYSELMQRPLTQLVHPDDLQATLEENANVGRGKVTNRFVNRM
HHHCCEECCHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHH
RHRDGSYRWLSWSAVADGGRIYSAARDITSEIAAVDKLAEANRELRAQIQERERVEATLQ
HCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QMQRLEAVGQLTAGVAHDFNNLLTVILTSASFLKNDLEQGAPLERSLRRLQYIRESGERG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC
ATLTGQLLAFARRQQLAPTAIDLNDTLVSLLSLLKSTLGGSVSIETDTQADIWHALVDPT
CCHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHCCCC
QIEMIILNLAINARDAMGDGGRLTLGTRNVVVTEPALRAEDPAPGEYVVLSVTDTGTGMS
CEEEEEEEEEEECCCCCCCCCEEEEECCCEEEECCCCCCCCCCCCCEEEEEEECCCCCCH
EEVLSKAFEPFFTTKEVGKGSGLGLAQVFGFAKQSGGGARIESRVGVGTTVKVFLPRTAA
HHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHCCCCCCEEECCCCCCCEEEEEEECCCC
PEQPEQATALSAGSHDENSQHRILLVDDDHSVREVTAQMLENLGFAVTEAESGDHALQLL
CCCCCHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEECCCCHHHHHHH
RDGAAVDLLLADFAMPGMNGGELARAVRVRRPQLPVVFVTGYAELCELGLDGYSIIQKPF
HCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEECCHHHHHHHCCCCHHHHHHHH
REEQLANKIHLALREGSLADG
HHHHHHHHHHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA