Click here to switch to the map view.

The map label for this gene is yafC [H]

Identifier: 146284460

GI number: 146284460

Start: 4501658

End: 4502575

Strand: Direct

Name: yafC [H]

Synonym: PST_4149

Alternate gene names: 146284460

Gene position: 4501658-4502575 (Clockwise)

Preceding gene: 146284459

Following gene: 146284463

Centisome position: 98.56

GC content: 67.65

Gene sequence:

>918_bases
ATGCGATTCCCACCGATGAAAACCAACCTCGACGAAATGCTCGCCTTTGTCAGCGTGGTCGACAGTGGCTCGATCAGCGC
TGCGGCCGAGCAGCTGGAACAGACCGCCTCGGGCGTTAGCCGGGCGTTGAGTCGGCTGGAGGACAAGCTGGCGGTGACAC
TGTTGCGCCGCACCACGCGGCGCCTCGAGCTGACCGAGGAAGGCGAGGCGTTCCTGGCGCAGGCGCGGCGGATTCTGGCC
AGCGTCGAGGAAGCCGAGGAGCAGATGGCGCTGCGGCGGCAGGCGCCGGCCGGGCGCTTGCGGGTCAATACCGCGTCGCC
GTTCATGCTGCATGTGATCGTCCCGCTGATCGGCGATTTCCGCGCGCGCTATCCGCTGATCGAGCTGGAGCTGCATAGCG
ATGACCGTATCGTCGATTTGTTGGAGCGGCGCATCGATCTGGCCATCCGCATCGGCCCCCTGCCCGATTCCAGCCTGCAT
GCACGGCCGCTGTGCCATACCACGCGCCGGGTGCTGGCGAGCCCGGCCTATCTGGCGCGGCATGGCACACCGCAAAAGGT
TGAGGACCTGGCGGAGCACAGCCTGATTGGCTTTACCGAGCCGGATCGCCTCAACGACTGGCCGCTGCGCCACGCGCTCG
GCGAGAGCTGGCGGATCAACCCGGCGCTACGCGCATCCAGCGGCGACACGGTGCGCGAGCTGGCGCTGGCCGGCGAAGGG
ATCGCCAGCCTGTCGGACTTCATGACTGGCCGGGACCGCCAGCGCGGCGAGCTGGTGGAGGTGCTGGCGGCACAGCGGGT
CGACGTGCGCCAGCCGATCAACGCGGTGTACTACCGCAACACCGCGCTGGCTTCGCGCATCACCTGTTTTCTGGATTATC
TGAGTGAGCGCCTGGGAGCCGGCGCCCCGCACGACTGA

Upstream 100 bases:

>100_bases
TTTCGCCAGCGGCTGATCGACGGATCCGCCGCCGGGGGCCCGCGCCGGTCCGGTTGCCGCCGCGCGGCGCTGCCGCCAGA
CTCGTTGTTCCCGCCCTTCG

Downstream 100 bases:

>100_bases
GCAGGGATCGCGCGTCCGGGTATCCACGGCGGTGGCGCCGGTCGAACGCCAGGAAGTGAAACGGCCCTGTCCATCGGGTC
ACCGATGGCAGGGCCGTTTC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MRFPPMKTNLDEMLAFVSVVDSGSISAAAEQLEQTASGVSRALSRLEDKLAVTLLRRTTRRLELTEEGEAFLAQARRILA
SVEEAEEQMALRRQAPAGRLRVNTASPFMLHVIVPLIGDFRARYPLIELELHSDDRIVDLLERRIDLAIRIGPLPDSSLH
ARPLCHTTRRVLASPAYLARHGTPQKVEDLAEHSLIGFTEPDRLNDWPLRHALGESWRINPALRASSGDTVRELALAGEG
IASLSDFMTGRDRQRGELVEVLAAQRVDVRQPINAVYYRNTALASRITCFLDYLSERLGAGAPHD

Sequences:

>Translated_305_residues
MRFPPMKTNLDEMLAFVSVVDSGSISAAAEQLEQTASGVSRALSRLEDKLAVTLLRRTTRRLELTEEGEAFLAQARRILA
SVEEAEEQMALRRQAPAGRLRVNTASPFMLHVIVPLIGDFRARYPLIELELHSDDRIVDLLERRIDLAIRIGPLPDSSLH
ARPLCHTTRRVLASPAYLARHGTPQKVEDLAEHSLIGFTEPDRLNDWPLRHALGESWRINPALRASSGDTVRELALAGEG
IASLSDFMTGRDRQRGELVEVLAAQRVDVRQPINAVYYRNTALASRITCFLDYLSERLGAGAPHD
>Mature_305_residues
MRFPPMKTNLDEMLAFVSVVDSGSISAAAEQLEQTASGVSRALSRLEDKLAVTLLRRTTRRLELTEEGEAFLAQARRILA
SVEEAEEQMALRRQAPAGRLRVNTASPFMLHVIVPLIGDFRARYPLIELELHSDDRIVDLLERRIDLAIRIGPLPDSSLH
ARPLCHTTRRVLASPAYLARHGTPQKVEDLAEHSLIGFTEPDRLNDWPLRHALGESWRINPALRASSGDTVRELALAGEG
IASLSDFMTGRDRQRGELVEVLAAQRVDVRQPINAVYYRNTALASRITCFLDYLSERLGAGAPHD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=293, Percent_Identity=47.4402730375427, Blast_Score=287, Evalue=7e-79,
Organism=Escherichia coli, GI1789639, Length=290, Percent_Identity=33.448275862069, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI87081978, Length=299, Percent_Identity=32.4414715719064, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI145693193, Length=292, Percent_Identity=31.5068493150685, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1789440, Length=293, Percent_Identity=30.3754266211604, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787128, Length=294, Percent_Identity=26.8707482993197, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787589, Length=291, Percent_Identity=27.1477663230241, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1789173, Length=263, Percent_Identity=30.0380228136882, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788706, Length=305, Percent_Identity=25.9016393442623, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790262, Length=276, Percent_Identity=26.4492753623188, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788481, Length=298, Percent_Identity=27.8523489932886, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI157672245, Length=152, Percent_Identity=32.8947368421053, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786448, Length=300, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693105, Length=166, Percent_Identity=30.7228915662651, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87082132, Length=317, Percent_Identity=23.9747634069401, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787879, Length=162, Percent_Identity=30.8641975308642, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790399, Length=286, Percent_Identity=23.7762237762238, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1787806, Length=159, Percent_Identity=28.3018867924528, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788748, Length=179, Percent_Identity=27.9329608938547, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33982; Mature: 33982

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFPPMKTNLDEMLAFVSVVDSGSISAAAEQLEQTASGVSRALSRLEDKLAVTLLRRTTR
CCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLELTEEGEAFLAQARRILASVEEAEEQMALRRQAPAGRLRVNTASPFMLHVIVPLIGDF
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHH
RARYPLIELELHSDDRIVDLLERRIDLAIRIGPLPDSSLHARPLCHTTRRVLASPAYLAR
HHCCCEEEEEECCCCHHHHHHHHHHCEEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHH
HGTPQKVEDLAEHSLIGFTEPDRLNDWPLRHALGESWRINPALRASSGDTVRELALAGEG
CCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCC
IASLSDFMTGRDRQRGELVEVLAAQRVDVRQPINAVYYRNTALASRITCFLDYLSERLGA
HHHHHHHHCCCCCHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GAPHD
CCCCC
>Mature Secondary Structure
MRFPPMKTNLDEMLAFVSVVDSGSISAAAEQLEQTASGVSRALSRLEDKLAVTLLRRTTR
CCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLELTEEGEAFLAQARRILASVEEAEEQMALRRQAPAGRLRVNTASPFMLHVIVPLIGDF
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHH
RARYPLIELELHSDDRIVDLLERRIDLAIRIGPLPDSSLHARPLCHTTRRVLASPAYLAR
HHCCCEEEEEECCCCHHHHHHHHHHCEEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHH
HGTPQKVEDLAEHSLIGFTEPDRLNDWPLRHALGESWRINPALRASSGDTVRELALAGEG
CCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCC
IASLSDFMTGRDRQRGELVEVLAAQRVDVRQPINAVYYRNTALASRITCFLDYLSERLGA
HHHHHHHHCCCCCHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GAPHD
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]