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The map label for this gene is 146283904

Identifier: 146283904

GI number: 146283904

Start: 3877369

End: 3878664

Strand: Direct

Name: 146283904

Synonym: PST_3587

Alternate gene names: NA

Gene position: 3877369-3878664 (Clockwise)

Preceding gene: 146283903

Following gene: 146283906

Centisome position: 84.89

GC content: 66.59

Gene sequence:

>1296_bases
ATGAAGCACTCGAGCGCATTGACCACCCTGGCCATGGCTGCCCTGCTCAGCGGCTGCGGCGGTGAAGAGCAGAACGCTGC
CCAGCATTACGGACCCGATCCCAAGCTGCCCGAACCGGAGCGTGGGCTGCTGCCGAGCATGAAGATCGCCGAGCCAACCC
CCTGGGGCGATCAGCTACCCACCGTGCCGGACGGTTTCAGCGTGACGGCAATTGCCACCGATCTGAAGATCCCCCGCCAG
ACGCTGGTGCTGCCCAACGGCGACATCCTGGTGGCCGAAGGCCGCGGCGGCAATGCACCCAAGCTCAAGCCCAAGGACGT
GATCGCCGACGTGATCAAGGCACGCGGCACCACCTCGGTGGAGAGCGGCGACCGTGTCACTCTGCTACGCGACGCCGATG
GCGATGGCGAGTACGAGCTGCAGACGGTGTTCGCCGAGGATCTCAACGCCCCCTACGGGCTGGCGTTCCACGACGGTAAC
CTCTACGTTGCCAATCAGGACGCGCTGGTGCGCTTCGACTATCAGGACGGCCAGACCGAGGCCAGCGGCCCGCCGACCCA
GGTGGCCGAACTGCCCTCCGAGATCAATCACCACTGGACCAAGGCGCTGACCATCAGCCCCGATGGTCAGTACCTCTATG
TCGGCATCGGCTCCAACAGCAACATCACCGAGCGCGGCATGGAAGCCGAGATCGACCGCGCCATGGTCTGGCAGATCAAC
GCGGAAACCGGCGCCTACAAGCCCTACGCCACCGGCCTGCGCAACCCGACCGCGCTGGCGATCCAGCCAGGCTCGGGGCA
GCTCTGGGCGGTGGTCAACGAGCGCGACGAACTGGGAGAAGACCTGGTGCCGGATTATCTGACGTCGGTCAAGGAAGGCG
GCTTCTACGGCTGGCCTTACGCCTACTGGGGCCAGAACGTCGATGACCGCGTGCGCCCGCAGGACCCGGACAAGGTCGCC
GCCAGCATCACGCCGGACTACGCCCTGGGCTCGCACGTCGCCGCACTGGGCCTGGATTTTTCGTCCGACGTGATGGGCGA
GCGCTTCGCCGAGGGTGTGTTCATCGGCGAGCACGGCAGCTGGAACCGCAAGGAACCGGTCGGCTACAAGGTGATCTTCG
TCCCCTTCCAGAACGGCCGCCCCGCCGGCCAGCCGATCGACTTCGTCACCGGCTTTCGTACCGACGACGGCAAGACCCGC
GGCCGCCCCGTCGGCGTGACGGTAGACCCACGCGGCGCGCTGATCGTCGCCGATGACCTGGCCAACGTGGTGTGGCGAGT
GACGCGGGAGCAGTGA

Upstream 100 bases:

>100_bases
CGACCATGCCCCAAGGGCTGGTGCTCTCGGTGATCGTCACCCTGCTGGCCTGCGCGGCCAGCTGGATCGGCCTGAGCAAC
CTGCGCTCGGGAGGTGAAGC

Downstream 100 bases:

>100_bases
TGGACAGCCGGCCGGTGGCCCGGGTCACCGGCCGGTCTCATGCACCCTGAGCTCAGCCTGTCGCTGTGCCAAGCAGGCTC
TTCAGCCGCTGCAGATCGGC

Product: L-sorbosone dehydrogenase

Products: NA

Alternate protein names: SNDH [H]

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MKHSSALTTLAMAALLSGCGGEEQNAAQHYGPDPKLPEPERGLLPSMKIAEPTPWGDQLPTVPDGFSVTAIATDLKIPRQ
TLVLPNGDILVAEGRGGNAPKLKPKDVIADVIKARGTTSVESGDRVTLLRDADGDGEYELQTVFAEDLNAPYGLAFHDGN
LYVANQDALVRFDYQDGQTEASGPPTQVAELPSEINHHWTKALTISPDGQYLYVGIGSNSNITERGMEAEIDRAMVWQIN
AETGAYKPYATGLRNPTALAIQPGSGQLWAVVNERDELGEDLVPDYLTSVKEGGFYGWPYAYWGQNVDDRVRPQDPDKVA
ASITPDYALGSHVAALGLDFSSDVMGERFAEGVFIGEHGSWNRKEPVGYKVIFVPFQNGRPAGQPIDFVTGFRTDDGKTR
GRPVGVTVDPRGALIVADDLANVVWRVTREQ

Sequences:

>Translated_431_residues
MKHSSALTTLAMAALLSGCGGEEQNAAQHYGPDPKLPEPERGLLPSMKIAEPTPWGDQLPTVPDGFSVTAIATDLKIPRQ
TLVLPNGDILVAEGRGGNAPKLKPKDVIADVIKARGTTSVESGDRVTLLRDADGDGEYELQTVFAEDLNAPYGLAFHDGN
LYVANQDALVRFDYQDGQTEASGPPTQVAELPSEINHHWTKALTISPDGQYLYVGIGSNSNITERGMEAEIDRAMVWQIN
AETGAYKPYATGLRNPTALAIQPGSGQLWAVVNERDELGEDLVPDYLTSVKEGGFYGWPYAYWGQNVDDRVRPQDPDKVA
ASITPDYALGSHVAALGLDFSSDVMGERFAEGVFIGEHGSWNRKEPVGYKVIFVPFQNGRPAGQPIDFVTGFRTDDGKTR
GRPVGVTVDPRGALIVADDLANVVWRVTREQ
>Mature_431_residues
MKHSSALTTLAMAALLSGCGGEEQNAAQHYGPDPKLPEPERGLLPSMKIAEPTPWGDQLPTVPDGFSVTAIATDLKIPRQ
TLVLPNGDILVAEGRGGNAPKLKPKDVIADVIKARGTTSVESGDRVTLLRDADGDGEYELQTVFAEDLNAPYGLAFHDGN
LYVANQDALVRFDYQDGQTEASGPPTQVAELPSEINHHWTKALTISPDGQYLYVGIGSNSNITERGMEAEIDRAMVWQIN
AETGAYKPYATGLRNPTALAIQPGSGQLWAVVNERDELGEDLVPDYLTSVKEGGFYGWPYAYWGQNVDDRVRPQDPDKVA
ASITPDYALGSHVAALGLDFSSDVMGERFAEGVFIGEHGSWNRKEPVGYKVIFVPFQNGRPAGQPIDFVTGFRTDDGKTR
GRPVGVTVDPRGALIVADDLANVVWRVTREQ

Specific function: Converts L-sorbosone into 2-keto-L-gulonic acid (2KGA) [H]

COG id: COG2133

COG function: function code G; Glucose/sorbosone dehydrogenases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.burgdorferi BB024 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR012938
- InterPro:   IPR011041 [H]

Pfam domain/function: PF07995 GSDH [H]

EC number: NA

Molecular weight: Translated: 46616; Mature: 46616

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHSSALTTLAMAALLSGCGGEEQNAAQHYGPDPKLPEPERGLLPSMKIAEPTPWGDQLP
CCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TVPDGFSVTAIATDLKIPRQTLVLPNGDILVAEGRGGNAPKLKPKDVIADVIKARGTTSV
CCCCCCEEEEEEECCCCCCEEEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCC
ESGDRVTLLRDADGDGEYELQTVFAEDLNAPYGLAFHDGNLYVANQDALVRFDYQDGQTE
CCCCEEEEEEECCCCCCEEEEEEEHHHCCCCEEEEEECCEEEEECCCEEEEEECCCCCCC
ASGPPTQVAELPSEINHHWTKALTISPDGQYLYVGIGSNSNITERGMEAEIDRAMVWQIN
CCCCCHHHHHHHHHHCCCEEEEEEECCCCCEEEEEECCCCCHHHCCCHHCCCEEEEEEEE
AETGAYKPYATGLRNPTALAIQPGSGQLWAVVNERDELGEDLVPDYLTSVKEGGFYGWPY
CCCCCCCCHHHCCCCCEEEEEECCCCCEEEEECCHHHCCHHHHHHHHHHHHCCCCCCCCH
AYWGQNVDDRVRPQDPDKVAASITPDYALGSHVAALGLDFSSDVMGERFAEGVFIGEHGS
HHCCCCCCCCCCCCCCCCEEEECCCCHHHCCCEEEEECCCCHHHHHHHHHCCEEEECCCC
WNRKEPVGYKVIFVPFQNGRPAGQPIDFVTGFRTDDGKTRGRPVGVTVDPRGALIVADDL
CCCCCCCCEEEEEEECCCCCCCCCCCCCEECEECCCCCCCCCEEEEEECCCCCEEEHHHH
ANVVWRVTREQ
HHHHHEEECCC
>Mature Secondary Structure
MKHSSALTTLAMAALLSGCGGEEQNAAQHYGPDPKLPEPERGLLPSMKIAEPTPWGDQLP
CCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TVPDGFSVTAIATDLKIPRQTLVLPNGDILVAEGRGGNAPKLKPKDVIADVIKARGTTSV
CCCCCCEEEEEEECCCCCCEEEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCC
ESGDRVTLLRDADGDGEYELQTVFAEDLNAPYGLAFHDGNLYVANQDALVRFDYQDGQTE
CCCCEEEEEEECCCCCCEEEEEEEHHHCCCCEEEEEECCEEEEECCCEEEEEECCCCCCC
ASGPPTQVAELPSEINHHWTKALTISPDGQYLYVGIGSNSNITERGMEAEIDRAMVWQIN
CCCCCHHHHHHHHHHCCCEEEEEEECCCCCEEEEEECCCCCHHHCCCHHCCCEEEEEEEE
AETGAYKPYATGLRNPTALAIQPGSGQLWAVVNERDELGEDLVPDYLTSVKEGGFYGWPY
CCCCCCCCHHHCCCCCEEEEEECCCCCEEEEECCHHHCCHHHHHHHHHHHHCCCCCCCCH
AYWGQNVDDRVRPQDPDKVAASITPDYALGSHVAALGLDFSSDVMGERFAEGVFIGEHGS
HHCCCCCCCCCCCCCCCCEEEECCCCHHHCCCEEEEECCCCHHHHHHHHHCCEEEECCCC
WNRKEPVGYKVIFVPFQNGRPAGQPIDFVTGFRTDDGKTRGRPVGVTVDPRGALIVADDL
CCCCCCCCEEEEEEECCCCCCCCCCCCCEECEECCCCCCCCCEEEEEECCCCCEEEHHHH
ANVVWRVTREQ
HHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7574579 [H]