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The map label for this gene is lutB [H]

Identifier: 146283656

GI number: 146283656

Start: 3612556

End: 3614016

Strand: Direct

Name: lutB [H]

Synonym: PST_3338

Alternate gene names: 146283656

Gene position: 3612556-3614016 (Clockwise)

Preceding gene: 146283655

Following gene: 146283657

Centisome position: 79.09

GC content: 64.41

Gene sequence:

>1461_bases
ATGAACGCCGAACAGCGCATCCCAGCGATCCAGATCGAGAACGCCGGTGACCCGGACTTCCGCGCCCGCGCCCGCAAGTC
CCTGAAGGACGACCAGCTGCGACGCAACTTCCGAACCGCCATGGATTCGCTGATGACCAAGCGCGCCGCGGCCTTCAGCG
ATGCCGACGAGCGCGAGCGGCTGCGCGAGATGGGTAACCATATCCGCGCCCGCGCCTTGTCCAAGCTGCCCGAACTGCTG
GAGCGACTGGAAGCCAACCTGACCCGCAACGGTGTGAAAGTGCACTGGGCGGAGACGGTCGAGGAGGCCAACAACATCGT
CCTCGCGATCGCCCAGGCACGTCAGGCGAAACAGGTGATCAAGGGCAAATCGATGGTCAGCGAAGAAATGGAGATGAACC
ATTTCCTCGAAGGCCACGGGATCGAGAGCCTGGAATCAGACATGGGCGAGTACATCGTCCAGCTCGACCACGAAAAGCCG
TCCCACATCATCATGCCGGCGATCCACAAGAATGCCGGCCAGGTCGCCTCGCTGTTCCATGACAAGCTCGGCGTGGAATA
CACCAAGGATGTCGACCAGCTCATCCAGATCGGCCGCCGTACGCTGCGGCAGAAATTCTTCGAGGCCGATATCGGCGTCT
CCGGTGTGAACTTCGCGGTAGCCGAAACCGGCACCCTGCTGCTGGTGGAAAACGAAGGCAACGGCCGCATGAGCACCACA
GTGCCACCGGTGCACATCGCCGTCACCGGTATCGAGAAGGTGGTGGAGAATCTGCGCGACGTGGTCCCGCTGCTCTCCTT
GCTGACCCGCTCCGCGCTGGGCCAGCCCATCACTACCTACGTCAACATGATCTCCGGCCCGCGCAAGGCGCATGAGCTGG
ACGGTCCGCAGGAAGTGCACCTGATCCTGCTGGACAACGGCCGCAGCCAGGCCTTCGCCGACAGCGAGCTGCGCCAGACG
CTCAACTGCATCCGTTGCGGCGCCTGCATGAACCACTGCCCGGTGTACACCCGCGTCGGCGGCCACACCTACGGCGAGGT
CTATCCCGGGCCGATCGGCAAGATCATCACTCCGCACATGGTCGGTCTGGACAAGGTGCCGGACCACCCTAGCGCCTCGT
CGCTGTGTGGCGCCTGCGGCGAAGTCTGCCCGGTGAAGATTCCGATTCCGACCATCCTGCGGCGCCTGCGCGAGGAGAAC
GTCAAGGCACCGGACGACCCGCACAAGGTCATGCGCGGCCAGGGCAGCAAGTACTCTCGCAAGGAGCGGCTGATCTGGGC
CGGCTGGCGCCTGCTCAACACCAGCCCGACGCTGTACCGCGTATTCGGCTTCTTCGCCACACGCCTGCGCGGCCTGACGC
CATCGAACATCGGCCCCTGGACGCAGAACCACAGCGCACCGAAACCTGCCGCCCGCTCGCTGCACGAGCTGGCTCGCGAG
CACCTGGAGGGCAAGCGATGA

Upstream 100 bases:

>100_bases
GCTGCCTGATGAACATCAACGGCTCGCTGGAAAAGCAGCGCGAATCCCTGCGCGGCCAGCATCTGGCGAGCTTCCTCTGG
CAACGCACCGGAGGTGCCCG

Downstream 100 bases:

>100_bases
GCGCCAAGGCCAATATCCTCGCCAAGCTGAAGAAAAGCCTGGAAGGCACCACGCCGGTGGTCGATGACTACGACGCGTCG
CTGGTCACCCAGCCCTGGAG

Product: iron-sulphur protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MNAEQRIPAIQIENAGDPDFRARARKSLKDDQLRRNFRTAMDSLMTKRAAAFSDADERERLREMGNHIRARALSKLPELL
ERLEANLTRNGVKVHWAETVEEANNIVLAIAQARQAKQVIKGKSMVSEEMEMNHFLEGHGIESLESDMGEYIVQLDHEKP
SHIIMPAIHKNAGQVASLFHDKLGVEYTKDVDQLIQIGRRTLRQKFFEADIGVSGVNFAVAETGTLLLVENEGNGRMSTT
VPPVHIAVTGIEKVVENLRDVVPLLSLLTRSALGQPITTYVNMISGPRKAHELDGPQEVHLILLDNGRSQAFADSELRQT
LNCIRCGACMNHCPVYTRVGGHTYGEVYPGPIGKIITPHMVGLDKVPDHPSASSLCGACGEVCPVKIPIPTILRRLREEN
VKAPDDPHKVMRGQGSKYSRKERLIWAGWRLLNTSPTLYRVFGFFATRLRGLTPSNIGPWTQNHSAPKPAARSLHELARE
HLEGKR

Sequences:

>Translated_486_residues
MNAEQRIPAIQIENAGDPDFRARARKSLKDDQLRRNFRTAMDSLMTKRAAAFSDADERERLREMGNHIRARALSKLPELL
ERLEANLTRNGVKVHWAETVEEANNIVLAIAQARQAKQVIKGKSMVSEEMEMNHFLEGHGIESLESDMGEYIVQLDHEKP
SHIIMPAIHKNAGQVASLFHDKLGVEYTKDVDQLIQIGRRTLRQKFFEADIGVSGVNFAVAETGTLLLVENEGNGRMSTT
VPPVHIAVTGIEKVVENLRDVVPLLSLLTRSALGQPITTYVNMISGPRKAHELDGPQEVHLILLDNGRSQAFADSELRQT
LNCIRCGACMNHCPVYTRVGGHTYGEVYPGPIGKIITPHMVGLDKVPDHPSASSLCGACGEVCPVKIPIPTILRRLREEN
VKAPDDPHKVMRGQGSKYSRKERLIWAGWRLLNTSPTLYRVFGFFATRLRGLTPSNIGPWTQNHSAPKPAARSLHELARE
HLEGKR
>Mature_486_residues
MNAEQRIPAIQIENAGDPDFRARARKSLKDDQLRRNFRTAMDSLMTKRAAAFSDADERERLREMGNHIRARALSKLPELL
ERLEANLTRNGVKVHWAETVEEANNIVLAIAQARQAKQVIKGKSMVSEEMEMNHFLEGHGIESLESDMGEYIVQLDHEKP
SHIIMPAIHKNAGQVASLFHDKLGVEYTKDVDQLIQIGRRTLRQKFFEADIGVSGVNFAVAETGTLLLVENEGNGRMSTT
VPPVHIAVTGIEKVVENLRDVVPLLSLLTRSALGQPITTYVNMISGPRKAHELDGPQEVHLILLDNGRSQAFADSELRQT
LNCIRCGACMNHCPVYTRVGGHTYGEVYPGPIGKIITPHMVGLDKVPDHPSASSLCGACGEVCPVKIPIPTILRRLREEN
VKAPDDPHKVMRGQGSKYSRKERLIWAGWRLLNTSPTLYRVFGFFATRLRGLTPSNIGPWTQNHSAPKPAARSLHELARE
HLEGKR

Specific function: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate [H]

COG id: COG1139

COG function: function code C; Uncharacterized conserved protein containing a ferredoxin-like domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1786498, Length=475, Percent_Identity=39.1578947368421, Blast_Score=361, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017900
- InterPro:   IPR003741
- InterPro:   IPR004452
- InterPro:   IPR002698
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR022825 [H]

Pfam domain/function: PF02589 DUF162 [H]

EC number: NA

Molecular weight: Translated: 54174; Mature: 54174

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAEQRIPAIQIENAGDPDFRARARKSLKDDQLRRNFRTAMDSLMTKRAAAFSDADERER
CCCCCCCCEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LREMGNHIRARALSKLPELLERLEANLTRNGVKVHWAETVEEANNIVLAIAQARQAKQVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCEEEEHHHHHHHHHHH
KGKSMVSEEMEMNHFLEGHGIESLESDMGEYIVQLDHEKPSHIIMPAIHKNAGQVASLFH
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEECCCCCCCEECHHHHCCHHHHHHHHH
DKLGVEYTKDVDQLIQIGRRTLRQKFFEADIGVSGVNFAVAETGTLLLVENEGNGRMSTT
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEEECCCCEEECC
VPPVHIAVTGIEKVVENLRDVVPLLSLLTRSALGQPITTYVNMISGPRKAHELDGPQEVH
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHCCCCCEEE
LILLDNGRSQAFADSELRQTLNCIRCGACMNHCPVYTRVGGHTYGEVYPGPIGKIITPHM
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCHH
VGLDKVPDHPSASSLCGACGEVCPVKIPIPTILRRLREENVKAPDDPHKVMRGQGSKYSR
CCCCCCCCCCCHHHHHHHCCCCCEEEECHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCHH
KERLIWAGWRLLNTSPTLYRVFGFFATRLRGLTPSNIGPWTQNHSAPKPAARSLHELARE
HHCEEEECEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
HLEGKR
HCCCCC
>Mature Secondary Structure
MNAEQRIPAIQIENAGDPDFRARARKSLKDDQLRRNFRTAMDSLMTKRAAAFSDADERER
CCCCCCCCEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LREMGNHIRARALSKLPELLERLEANLTRNGVKVHWAETVEEANNIVLAIAQARQAKQVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCEEEEHHHHHHHHHHH
KGKSMVSEEMEMNHFLEGHGIESLESDMGEYIVQLDHEKPSHIIMPAIHKNAGQVASLFH
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEECCCCCCCEECHHHHCCHHHHHHHHH
DKLGVEYTKDVDQLIQIGRRTLRQKFFEADIGVSGVNFAVAETGTLLLVENEGNGRMSTT
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEEECCCCEEECC
VPPVHIAVTGIEKVVENLRDVVPLLSLLTRSALGQPITTYVNMISGPRKAHELDGPQEVH
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHCCCCCEEE
LILLDNGRSQAFADSELRQTLNCIRCGACMNHCPVYTRVGGHTYGEVYPGPIGKIITPHM
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCHH
VGLDKVPDHPSASSLCGACGEVCPVKIPIPTILRRLREENVKAPDDPHKVMRGQGSKYSR
CCCCCCCCCCCHHHHHHHCCCCCEEEECHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCHH
KERLIWAGWRLLNTSPTLYRVFGFFATRLRGLTPSNIGPWTQNHSAPKPAARSLHELARE
HHCEEEECEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
HLEGKR
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA