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The map label for this gene is dipZ [H]

Identifier: 146283591

GI number: 146283591

Start: 3537045

End: 3538841

Strand: Direct

Name: dipZ [H]

Synonym: PST_3271

Alternate gene names: 146283591

Gene position: 3537045-3538841 (Clockwise)

Preceding gene: 146283590

Following gene: 146283592

Centisome position: 77.44

GC content: 65.39

Gene sequence:

>1797_bases
ATGCCGGCACAGCTTTACCGTGAGATCGCCATGCTTCGCCTCCTGAGCCTGCTGCTCCTGCTATTCGTGCTCCCCGCCAA
CGCCGGCCTGTTCGACAACAAGCCCAGCGCCACCTTCGGCAGTGCGCTGAACAACAGCGGTGACTTCCTGCCGGTGCGCG
AGGCGTTCAGACTCAGCCTTGTCGATGCAAAGCCCGAGCAGATCACTCTGCGCTTCGTCGCAGCAGAGGGCTACTACCTC
TATCGGCACCGTTTTGCGTTCCAGACCGACGAGCCGGGCGTAGAAATCGGCGAGGCGCAACTGCCCGACGGAGTTGCCAA
GGTCGACGACTATTTCGGCGAGATCGAGGCCTATTACGGCATCCTCGACATCGAAATCCCCATAACCAACCCTGACAATC
GCCCCTTCGTCCTTCAGGTTTCCTACCAGGGCTGTGCCGACAAAGGCCTGTGTTACCCGCCGGAAACCGAATCGCTTTCC
ATTGGTGACGGAGCCACACCAAGCACTGCAGAGGGTAGCGAAACAGGTAGCCGCGATCTTTCCTGGCGCTCCATCGCACT
GTTCTTCCTCGCCGGCCTGGGCCTGACCTTCACGCCTTGCGTGCTACCGATGCTGCCAATCCTCACCGGGGTGGTTTTGC
GCGACCAGCCCGGAGGCATGCGCAGCTTCCTGCTGTCGGTGACCTATGTACTGCCGATGGCCGGCGGTTTCGCCGTACTC
GGCGCACTGATGGGCGTGTTCGGTGCCGAGCTGAATCTGCAGGCACGCCTGCAGTCGGCGTGGATTCTCGTGCCCTTCGC
ACTGTTCTTCGTGGTCTTCGCGCTGGCCATGTTCGGCCTGTTCGAGCTGCGCCTGCCGCAGGCCTTGAGCGGCCGCCTCG
ACCGTCTGGCCGGCAGCGCCCGCGGCGGTTCGTTCACTGGCGCCGCGATGCTGGGGGCGGTGTCCAGCCTGCTGGTATCG
CCGTGCGTCTCCGCACCGCTGGCCGGTGCACTGCTCTATATCAGCGCCAGCGGCGACGCCGTGGGCGGCGGGCTGAAGCT
GTTCGCCCTGGGCCTGGGCATGGGCGCGCCTCTGGTGTTGTTCGCCACCGGTGGTGGAGCCCTGTTGCCCAAGAGTGGGC
CCTGGATGGTCGGCGTGCGCAACCTCTTCGGCGTGCTGCTGCTGGCCGTTGCGATCTGGATGCTCGAGCGCGTCCTGCCA
GGCCCCATCGCCCTGGCACTCTGGGGATTGTTGGCGGCGGGCAGCGCGCTGTTCCTCGGCACCCTGGAGCTCACCAGCAA
GACGCCTCGTCAGAAGCTTGCCCAGCTGCTCGGCCTGGCCCTGCTGGTCTACGCTCTTGCCGCCTGGGTCGGCGCTTTGC
AAGGCGGCTCCGATCCGCTGCGGCCGCTGCCGATGGCCAGCGGCAGCGCGCCGGGCAGCCAGGCGGGCGAAGGTTGGCAT
ACGGTTTCCACGCCTGCGGAACTGGACGCGCAACTGGCCGCTGCCCGTGCCGCCGGCCAGCCGCTGATGCTGGACTGGTA
TGCCGATTGGTGCATCAGCTGCAAGGTCATCGAACGCGAGGTCTTCGCCAATCCGCAAGTGGCTCCGCGCCTGACCGACT
ATCGTCTAATCCGCTTCGATATCACCGAGAGCAATGCCGCCCAGCGCAGCCTGCTGGACCGCTACAAGCTGTTCGGCCCG
CCCGCCATCCTGTTCTTCGGTGGCGACGGAAAAGAGCTCAACGAGGTCCGCGTAGTCGGCGAGATAGACGCCTCCGGCTT
CGCCGAGCGACTGGATCGAGCAGCAGCTCTTCGCTAG

Upstream 100 bases:

>100_bases
CGTCAGCTCCGTGGAATCGAAAAGCACGACAGCATCTGGTTGCAAACTGATCGGCAGAGCGACAGTTGAGCGCGGGCGCC
GGACGCCGGCCGCGGTTATC

Downstream 100 bases:

>100_bases
GTGCGGAACGCAATCCCCACGCTTTGTCGCAAATACTCGAGACATCCCTACGGCCGACGAATGATTGCCGGAATCTTCAG
ACATAATGCGGGCATTTCCT

Product: thiol:disulfide interchange protein precursor

Products: NA

Alternate protein names: Protein-disulfide reductase 1; Disulfide reductase 1 [H]

Number of amino acids: Translated: 598; Mature: 597

Protein sequence:

>598_residues
MPAQLYREIAMLRLLSLLLLLFVLPANAGLFDNKPSATFGSALNNSGDFLPVREAFRLSLVDAKPEQITLRFVAAEGYYL
YRHRFAFQTDEPGVEIGEAQLPDGVAKVDDYFGEIEAYYGILDIEIPITNPDNRPFVLQVSYQGCADKGLCYPPETESLS
IGDGATPSTAEGSETGSRDLSWRSIALFFLAGLGLTFTPCVLPMLPILTGVVLRDQPGGMRSFLLSVTYVLPMAGGFAVL
GALMGVFGAELNLQARLQSAWILVPFALFFVVFALAMFGLFELRLPQALSGRLDRLAGSARGGSFTGAAMLGAVSSLLVS
PCVSAPLAGALLYISASGDAVGGGLKLFALGLGMGAPLVLFATGGGALLPKSGPWMVGVRNLFGVLLLAVAIWMLERVLP
GPIALALWGLLAAGSALFLGTLELTSKTPRQKLAQLLGLALLVYALAAWVGALQGGSDPLRPLPMASGSAPGSQAGEGWH
TVSTPAELDAQLAAARAAGQPLMLDWYADWCISCKVIEREVFANPQVAPRLTDYRLIRFDITESNAAQRSLLDRYKLFGP
PAILFFGGDGKELNEVRVVGEIDASGFAERLDRAAALR

Sequences:

>Translated_598_residues
MPAQLYREIAMLRLLSLLLLLFVLPANAGLFDNKPSATFGSALNNSGDFLPVREAFRLSLVDAKPEQITLRFVAAEGYYL
YRHRFAFQTDEPGVEIGEAQLPDGVAKVDDYFGEIEAYYGILDIEIPITNPDNRPFVLQVSYQGCADKGLCYPPETESLS
IGDGATPSTAEGSETGSRDLSWRSIALFFLAGLGLTFTPCVLPMLPILTGVVLRDQPGGMRSFLLSVTYVLPMAGGFAVL
GALMGVFGAELNLQARLQSAWILVPFALFFVVFALAMFGLFELRLPQALSGRLDRLAGSARGGSFTGAAMLGAVSSLLVS
PCVSAPLAGALLYISASGDAVGGGLKLFALGLGMGAPLVLFATGGGALLPKSGPWMVGVRNLFGVLLLAVAIWMLERVLP
GPIALALWGLLAAGSALFLGTLELTSKTPRQKLAQLLGLALLVYALAAWVGALQGGSDPLRPLPMASGSAPGSQAGEGWH
TVSTPAELDAQLAAARAAGQPLMLDWYADWCISCKVIEREVFANPQVAPRLTDYRLIRFDITESNAAQRSLLDRYKLFGP
PAILFFGGDGKELNEVRVVGEIDASGFAERLDRAAALR
>Mature_597_residues
PAQLYREIAMLRLLSLLLLLFVLPANAGLFDNKPSATFGSALNNSGDFLPVREAFRLSLVDAKPEQITLRFVAAEGYYLY
RHRFAFQTDEPGVEIGEAQLPDGVAKVDDYFGEIEAYYGILDIEIPITNPDNRPFVLQVSYQGCADKGLCYPPETESLSI
GDGATPSTAEGSETGSRDLSWRSIALFFLAGLGLTFTPCVLPMLPILTGVVLRDQPGGMRSFLLSVTYVLPMAGGFAVLG
ALMGVFGAELNLQARLQSAWILVPFALFFVVFALAMFGLFELRLPQALSGRLDRLAGSARGGSFTGAAMLGAVSSLLVSP
CVSAPLAGALLYISASGDAVGGGLKLFALGLGMGAPLVLFATGGGALLPKSGPWMVGVRNLFGVLLLAVAIWMLERVLPG
PIALALWGLLAAGSALFLGTLELTSKTPRQKLAQLLGLALLVYALAAWVGALQGGSDPLRPLPMASGSAPGSQAGEGWHT
VSTPAELDAQLAAARAAGQPLMLDWYADWCISCKVIEREVFANPQVAPRLTDYRLIRFDITESNAAQRSLLDRYKLFGPP
AILFFGGDGKELNEVRVVGEIDASGFAERLDRAAALR

Specific function: Involved in the formation of correct disulfide bonds in some periplasmic proteins and in the assembly of the periplasmic C-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=590, Percent_Identity=35.0847457627119, Blast_Score=336, Evalue=3e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 63494; Mature: 63362

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAQLYREIAMLRLLSLLLLLFVLPANAGLFDNKPSATFGSALNNSGDFLPVREAFRLSL
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCEEEHHHHHEEEE
VDAKPEQITLRFVAAEGYYLYRHRFAFQTDEPGVEIGEAQLPDGVAKVDDYFGEIEAYYG
ECCCCCEEEEEEEEECCEEEEEEEEEECCCCCCCEECCCCCCCCHHHHHHHHHHHHHEEE
ILDIEIPITNPDNRPFVLQVSYQGCADKGLCYPPETESLSIGDGATPSTAEGSETGSRDL
EEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCC
SWRSIALFFLAGLGLTFTPCVLPMLPILTGVVLRDQPGGMRSFLLSVTYVLPMAGGFAVL
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHHCCCHHHHH
GALMGVFGAELNLQARLQSAWILVPFALFFVVFALAMFGLFELRLPQALSGRLDRLAGSA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
RGGSFTGAAMLGAVSSLLVSPCVSAPLAGALLYISASGDAVGGGLKLFALGLGMGAPLVL
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEHHHHCCCCCCEEE
FATGGGALLPKSGPWMVGVRNLFGVLLLAVAIWMLERVLPGPIALALWGLLAAGSALFLG
EECCCCEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEE
TLELTSKTPRQKLAQLLGLALLVYALAAWVGALQGGSDPLRPLPMASGSAPGSQAGEGWH
EEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCE
TVSTPAELDAQLAAARAAGQPLMLDWYADWCISCKVIEREVFANPQVAPRLTDYRLIRFD
ECCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEE
ITESNAAQRSLLDRYKLFGPPAILFFGGDGKELNEVRVVGEIDASGFAERLDRAAALR
ECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEECCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PAQLYREIAMLRLLSLLLLLFVLPANAGLFDNKPSATFGSALNNSGDFLPVREAFRLSL
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCEEEHHHHHEEEE
VDAKPEQITLRFVAAEGYYLYRHRFAFQTDEPGVEIGEAQLPDGVAKVDDYFGEIEAYYG
ECCCCCEEEEEEEEECCEEEEEEEEEECCCCCCCEECCCCCCCCHHHHHHHHHHHHHEEE
ILDIEIPITNPDNRPFVLQVSYQGCADKGLCYPPETESLSIGDGATPSTAEGSETGSRDL
EEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCC
SWRSIALFFLAGLGLTFTPCVLPMLPILTGVVLRDQPGGMRSFLLSVTYVLPMAGGFAVL
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHHCCCHHHHH
GALMGVFGAELNLQARLQSAWILVPFALFFVVFALAMFGLFELRLPQALSGRLDRLAGSA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
RGGSFTGAAMLGAVSSLLVSPCVSAPLAGALLYISASGDAVGGGLKLFALGLGMGAPLVL
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEHHHHCCCCCCEEE
FATGGGALLPKSGPWMVGVRNLFGVLLLAVAIWMLERVLPGPIALALWGLLAAGSALFLG
EECCCCEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEE
TLELTSKTPRQKLAQLLGLALLVYALAAWVGALQGGSDPLRPLPMASGSAPGSQAGEGWH
EEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCE
TVSTPAELDAQLAAARAAGQPLMLDWYADWCISCKVIEREVFANPQVAPRLTDYRLIRFD
ECCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEE
ITESNAAQRSLLDRYKLFGPPAILFFGGDGKELNEVRVVGEIDASGFAERLDRAAALR
ECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEECCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353916; 10984043 [H]