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The map label for this gene is crp [C]

Identifier: 146283586

GI number: 146283586

Start: 3532738

End: 3533622

Strand: Direct

Name: crp [C]

Synonym: PST_3266

Alternate gene names: 146283586

Gene position: 3532738-3533622 (Clockwise)

Preceding gene: 146283585

Following gene: 146283590

Centisome position: 77.35

GC content: 61.13

Gene sequence:

>885_bases
GTGATTTACTCGCTCGCCCGACCAGGCCTATTGTGCGCCGACGTGACCCTGCCAATCGTCTGCCCGTTTCGTTCAAGGAT
TACCGACATGTATTTACTCGGGGAGCAACCGGCGTACGCCGATCGCCTGATCACTCGCCTGCAAACCATTCCCACCCAGC
TGCTGGAAGGTCTGCAGCCATCGGGCCCCAACCTTGAACTCAAACACACCGACGACCTGTGCGCGGAGCTGCCTGCACAG
CAGCTGTTCATTATCGAGACCGGGCTGCTGCATGCGCTGATCGATGGCAAACCACTGTTCTACCTCCAGGAAGGCGATCT
GGTCGGCCTGCGCCAGCCGAGCGATCTGCCCGAATGTCGCTATTGCAGCGACGAGCCCATCAGCCTGGTGCCCTACTCGC
GCAACGCCGTGTTCCAGCACATCCATGCCGATGAACAGCGCCAGGAGTTGTTCACTCAGTACCTGATCGGTCACACCGCA
TTGCTGGGCGACGCCCTGGCGCGCCTCAAGCAGCCGGAGATCCGCCCCGCTACCGGCTTCAAGCATTTCGCCGTAGGTGA
GGAGCTCATTCGCCAGGGCGACGAAGCGGACAATGTATTCATCATCATCGAAGGCCACGCCGAAGCCATCGTCGACGGAC
AAAAGGTTGGCGACGTACAGAAGGACGAGATCTTCGGGGCCATGGCGGTGTTCACCCGCGAGCGGCGCAGCGCAACCGTG
GTCGCCAGCGAGCCATGCACTGTCATGGTCATTCCCAAGGAACAGTTCCTCGGCCTGACGCAAAGCAACCCGCGCATCGC
CCACAGCCTGATCGAGAGCATGGCCCGACGCATCGACCTGCTGAACAAGGAAGTCACTCACCTGCGGGTCAACGTCGCCG
TCTAG

Upstream 100 bases:

>100_bases
GTGCCCTGGCAGCAACTGCCGGCCCCGCTGAAGGAAGAACTTAATCGGAACCTGGGCAGCGAACTCGACAACTAGAGCTA
GCTCACAACCTCTGCGCGGC

Downstream 100 bases:

>100_bases
CGATCCGCTCGTCGCGGCCGCACATATATTTTTACGAATGCCTGTTGACGCAGAAATGAGAATTGTTATTATTATCGCAA
CTGATCGCGAGGTCAGCCGA

Product: cAMP-dependent protein kinase

Products: NA

Alternate protein names: Transcriptional Regulatory Protein Crp Family; Crp/Fnr Family Transcriptional Regulator

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MIYSLARPGLLCADVTLPIVCPFRSRITDMYLLGEQPAYADRLITRLQTIPTQLLEGLQPSGPNLELKHTDDLCAELPAQ
QLFIIETGLLHALIDGKPLFYLQEGDLVGLRQPSDLPECRYCSDEPISLVPYSRNAVFQHIHADEQRQELFTQYLIGHTA
LLGDALARLKQPEIRPATGFKHFAVGEELIRQGDEADNVFIIIEGHAEAIVDGQKVGDVQKDEIFGAMAVFTRERRSATV
VASEPCTVMVIPKEQFLGLTQSNPRIAHSLIESMARRIDLLNKEVTHLRVNVAV

Sequences:

>Translated_294_residues
MIYSLARPGLLCADVTLPIVCPFRSRITDMYLLGEQPAYADRLITRLQTIPTQLLEGLQPSGPNLELKHTDDLCAELPAQ
QLFIIETGLLHALIDGKPLFYLQEGDLVGLRQPSDLPECRYCSDEPISLVPYSRNAVFQHIHADEQRQELFTQYLIGHTA
LLGDALARLKQPEIRPATGFKHFAVGEELIRQGDEADNVFIIIEGHAEAIVDGQKVGDVQKDEIFGAMAVFTRERRSATV
VASEPCTVMVIPKEQFLGLTQSNPRIAHSLIESMARRIDLLNKEVTHLRVNVAV
>Mature_294_residues
MIYSLARPGLLCADVTLPIVCPFRSRITDMYLLGEQPAYADRLITRLQTIPTQLLEGLQPSGPNLELKHTDDLCAELPAQ
QLFIIETGLLHALIDGKPLFYLQEGDLVGLRQPSDLPECRYCSDEPISLVPYSRNAVFQHIHADEQRQELFTQYLIGHTA
LLGDALARLKQPEIRPATGFKHFAVGEELIRQGDEADNVFIIIEGHAEAIVDGQKVGDVQKDEIFGAMAVFTRERRSATV
VASEPCTVMVIPKEQFLGLTQSNPRIAHSLIESMARRIDLLNKEVTHLRVNVAV

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 32785; Mature: 32785

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00888 CNMP_BINDING_1 ; PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYSLARPGLLCADVTLPIVCPFRSRITDMYLLGEQPAYADRLITRLQTIPTQLLEGLQP
CCCCCCCCCEEEECCCEEEECCHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
SGPNLELKHTDDLCAELPAQQLFIIETGLLHALIDGKPLFYLQEGDLVGLRQPSDLPECR
CCCCEEEECCHHHHHHCCCCEEEEEEHHHHHHHCCCCEEEEEECCCEEECCCCCCCCCCC
YCSDEPISLVPYSRNAVFQHIHADEQRQELFTQYLIGHTALLGDALARLKQPEIRPATGF
CCCCCCCEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
KHFAVGEELIRQGDEADNVFIIIEGHAEAIVDGQKVGDVQKDEIFGAMAVFTRERRSATV
HHHHHHHHHHHCCCCCCCEEEEEECCHHEEECCHHHCCCCHHHHHHHHHHHHHHCCCEEE
VASEPCTVMVIPKEQFLGLTQSNPRIAHSLIESMARRIDLLNKEVTHLRVNVAV
EECCCEEEEEECHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEC
>Mature Secondary Structure
MIYSLARPGLLCADVTLPIVCPFRSRITDMYLLGEQPAYADRLITRLQTIPTQLLEGLQP
CCCCCCCCCEEEECCCEEEECCHHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
SGPNLELKHTDDLCAELPAQQLFIIETGLLHALIDGKPLFYLQEGDLVGLRQPSDLPECR
CCCCEEEECCHHHHHHCCCCEEEEEEHHHHHHHCCCCEEEEEECCCEEECCCCCCCCCCC
YCSDEPISLVPYSRNAVFQHIHADEQRQELFTQYLIGHTALLGDALARLKQPEIRPATGF
CCCCCCCEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
KHFAVGEELIRQGDEADNVFIIIEGHAEAIVDGQKVGDVQKDEIFGAMAVFTRERRSATV
HHHHHHHHHHHCCCCCCCEEEEEECCHHEEECCHHHCCCCHHHHHHHHHHHHHHCCCEEE
VASEPCTVMVIPKEQFLGLTQSNPRIAHSLIESMARRIDLLNKEVTHLRVNVAV
EECCCEEEEEECHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA