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The map label for this gene is 146283391

Identifier: 146283391

GI number: 146283391

Start: 3292505

End: 3293887

Strand: Direct

Name: 146283391

Synonym: PST_3062

Alternate gene names: NA

Gene position: 3292505-3293887 (Clockwise)

Preceding gene: 162139459

Following gene: 146283392

Centisome position: 72.09

GC content: 64.35

Gene sequence:

>1383_bases
ATGTATGCACTCATGGCTGTCGTGTTCGTCATAGGCTATCTATGCATAGCCTTCGAGCATCCCCTGAAGATCGACAAGGC
CGCTGCGGCGATTCTCACCGCGGTGCTCACCTGGACCATTCTGGTACTGGGTGCCGACCATATCCTCCCGCTGCTGCAAC
ACGGCAGCCACGATCCGGCGGATTCGTCGGCCGTGGTGGTCGAGGCGCTGCGCCACCACCTCGGTGAAGTGTCGGAGATC
CTGTTCTTCCTGCTCGGGGCGATGACCATCGTCGAGCTGATCGACTCCCACGAGGGCTTCAAGGCCATCACCGACCGCAT
CCAGACCCGCAAGCGCGTGCACCTGCTGTGGATCGTCGGCTTCCTCACCTTCTTCCTCTCCGCGGCACTGGACAACCTGA
CCACCACCATCGTCATGGTCTCGCTGCTGCGCAAGCTGATCCGCGGTCGCCCGGAGCGCTGGCTGTTCGTCGGCGTCGTG
GTGATCGCCGCCAACTCCGGCGGTGCCTGGTCGCCCATCGGTGACGTGACCACCACCATGCTCTGGATCGGCAATCAGAT
CACCGCCTCGGGCGTGATCGTCAACCTGTTCCTGCCGAGCCTGGTCTGCCTGCTGGTGCCGCTGATCATCCTCAGCTTCA
CCCTGCGCGGCGAAGCTCCACGGCCGCGGCCGCGTGCCCACCTGGCCGAGAAGCACCCGCCGACCACCACCGTTTTCGAG
CGCAACCTGGTGCTGGGTCTCGGCCTCGCCGCCCTGCTGTTCGTGCCGATCTTCAAGACCGTGACCCACCTGCCACCGTA
CATGGGCATTCTCTTCGGCCTCGGCGTGCTCTGGGTGACCACCGAATTCATCCACCGCAACAAGAATGCCGAGGACAAGC
ACCCGCTCTCGGTGGTCGGCGTGCTGCGCAAGGTCGACACCCCCAGCGTGCTGTTCTTCCTCGGCATCCTGCTGGCGGTT
TCCAGCCTGGCCACCGCGGGCCATCTGACCCAGGTTGCCACCGCGCTGCGCGAGTCGCTGGGCCATATCTATGCGATCAA
CTACGCCATCGGCCTGCTCTCGGCCGTGGTCGATAACGTGCCGCTGGTGGCCGGTGCGATGAAGATGTACCCGCTGGTGA
GCGAGAAGATGTTGGCGGCTACCGCTGCAGAAGAACTCGGCTGGATGTCGCAGTTCGTCGTCGACGGCAACTTCTGGGAA
ATGCTGGCCTACTGCGCCGGTACCGGCGGCAGCACGCTGATCATCGGCTCGGCCGCAGGTGTCGCCGCGATGGGCATGGA
GAAGATCAGCTTCACCTGGTACATCAAGCGCGTCAGCCTGCTGGCCTTCCTCGGTTACACTGCGGGCGCCGCGACCTACA
TCGGCATGCTCGCCCTGCGCTGA

Upstream 100 bases:

>100_bases
TTGTTTCACCTTCGACAGCCAATCGTGCCCCTGCCAGCCGCCGAGGCTGCGTCGCCACGTCCGCATGCCCGGCAAGGTTC
CTCAAGATGGAGTCCCTCCG

Downstream 100 bases:

>100_bases
ACGTAGCGAGCCCGGCCAGGTCGCAGTCCCCACAGACGACCTGGCCAGGGACCTTCCATGACCGTCAGCAAGACCAAAAC
CAGCTTCTACCGCCGACTCT

Product: Na+/H+ antiporter NhaD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MYALMAVVFVIGYLCIAFEHPLKIDKAAAAILTAVLTWTILVLGADHILPLLQHGSHDPADSSAVVVEALRHHLGEVSEI
LFFLLGAMTIVELIDSHEGFKAITDRIQTRKRVHLLWIVGFLTFFLSAALDNLTTTIVMVSLLRKLIRGRPERWLFVGVV
VIAANSGGAWSPIGDVTTTMLWIGNQITASGVIVNLFLPSLVCLLVPLIILSFTLRGEAPRPRPRAHLAEKHPPTTTVFE
RNLVLGLGLAALLFVPIFKTVTHLPPYMGILFGLGVLWVTTEFIHRNKNAEDKHPLSVVGVLRKVDTPSVLFFLGILLAV
SSLATAGHLTQVATALRESLGHIYAINYAIGLLSAVVDNVPLVAGAMKMYPLVSEKMLAATAAEELGWMSQFVVDGNFWE
MLAYCAGTGGSTLIIGSAAGVAAMGMEKISFTWYIKRVSLLAFLGYTAGAATYIGMLALR

Sequences:

>Translated_460_residues
MYALMAVVFVIGYLCIAFEHPLKIDKAAAAILTAVLTWTILVLGADHILPLLQHGSHDPADSSAVVVEALRHHLGEVSEI
LFFLLGAMTIVELIDSHEGFKAITDRIQTRKRVHLLWIVGFLTFFLSAALDNLTTTIVMVSLLRKLIRGRPERWLFVGVV
VIAANSGGAWSPIGDVTTTMLWIGNQITASGVIVNLFLPSLVCLLVPLIILSFTLRGEAPRPRPRAHLAEKHPPTTTVFE
RNLVLGLGLAALLFVPIFKTVTHLPPYMGILFGLGVLWVTTEFIHRNKNAEDKHPLSVVGVLRKVDTPSVLFFLGILLAV
SSLATAGHLTQVATALRESLGHIYAINYAIGLLSAVVDNVPLVAGAMKMYPLVSEKMLAATAAEELGWMSQFVVDGNFWE
MLAYCAGTGGSTLIIGSAAGVAAMGMEKISFTWYIKRVSLLAFLGYTAGAATYIGMLALR
>Mature_460_residues
MYALMAVVFVIGYLCIAFEHPLKIDKAAAAILTAVLTWTILVLGADHILPLLQHGSHDPADSSAVVVEALRHHLGEVSEI
LFFLLGAMTIVELIDSHEGFKAITDRIQTRKRVHLLWIVGFLTFFLSAALDNLTTTIVMVSLLRKLIRGRPERWLFVGVV
VIAANSGGAWSPIGDVTTTMLWIGNQITASGVIVNLFLPSLVCLLVPLIILSFTLRGEAPRPRPRAHLAEKHPPTTTVFE
RNLVLGLGLAALLFVPIFKTVTHLPPYMGILFGLGVLWVTTEFIHRNKNAEDKHPLSVVGVLRKVDTPSVLFFLGILLAV
SSLATAGHLTQVATALRESLGHIYAINYAIGLLSAVVDNVPLVAGAMKMYPLVSEKMLAATAAEELGWMSQFVVDGNFWE
MLAYCAGTGGSTLIIGSAAGVAAMGMEKISFTWYIKRVSLLAFLGYTAGAATYIGMLALR

Specific function: Unknown

COG id: COG1055

COG function: function code P; Na+/H+ antiporter NhaD and related arsenite permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitM (TC 2.A.11) transporter family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000802
- InterPro:   IPR004680 [H]

Pfam domain/function: PF03600 CitMHS [H]

EC number: NA

Molecular weight: Translated: 49770; Mature: 49770

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYALMAVVFVIGYLCIAFEHPLKIDKAAAAILTAVLTWTILVLGADHILPLLQHGSHDPA
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DSSAVVVEALRHHLGEVSEILFFLLGAMTIVELIDSHEGFKAITDRIQTRKRVHLLWIVG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
FLTFFLSAALDNLTTTIVMVSLLRKLIRGRPERWLFVGVVVIAANSGGAWSPIGDVTTTM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCHHHHHHHH
LWIGNQITASGVIVNLFLPSLVCLLVPLIILSFTLRGEAPRPRPRAHLAEKHPPTTTVFE
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCHHHH
RNLVLGLGLAALLFVPIFKTVTHLPPYMGILFGLGVLWVTTEFIHRNKNAEDKHPLSVVG
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
VLRKVDTPSVLFFLGILLAVSSLATAGHLTQVATALRESLGHIYAINYAIGLLSAVVDNV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHCC
PLVAGAMKMYPLVSEKMLAATAAEELGWMSQFVVDGNFWEMLAYCAGTGGSTLIIGSAAG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCC
VAAMGMEKISFTWYIKRVSLLAFLGYTAGAATYIGMLALR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYALMAVVFVIGYLCIAFEHPLKIDKAAAAILTAVLTWTILVLGADHILPLLQHGSHDPA
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DSSAVVVEALRHHLGEVSEILFFLLGAMTIVELIDSHEGFKAITDRIQTRKRVHLLWIVG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
FLTFFLSAALDNLTTTIVMVSLLRKLIRGRPERWLFVGVVVIAANSGGAWSPIGDVTTTM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCHHHHHHHH
LWIGNQITASGVIVNLFLPSLVCLLVPLIILSFTLRGEAPRPRPRAHLAEKHPPTTTVFE
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCHHHH
RNLVLGLGLAALLFVPIFKTVTHLPPYMGILFGLGVLWVTTEFIHRNKNAEDKHPLSVVG
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
VLRKVDTPSVLFFLGILLAVSSLATAGHLTQVATALRESLGHIYAINYAIGLLSAVVDNV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHCC
PLVAGAMKMYPLVSEKMLAATAAEELGWMSQFVVDGNFWEMLAYCAGTGGSTLIIGSAAG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCC
VAAMGMEKISFTWYIKRVSLLAFLGYTAGAATYIGMLALR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]