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The map label for this gene is yfhR [C]

Identifier: 146283254

GI number: 146283254

Start: 3143820

End: 3144746

Strand: Direct

Name: yfhR [C]

Synonym: PST_2919

Alternate gene names: 146283254

Gene position: 3143820-3144746 (Clockwise)

Preceding gene: 146283253

Following gene: 146283255

Centisome position: 68.83

GC content: 66.77

Gene sequence:

>927_bases
TTGCAGCGTTTCTTCCTGTTCCGCAGCAAGGCCCGCCGGCTCTGCCTGTTGCTGGTTGCCATGATCGCCGTTGGCCTGCC
GGTCGGCTGTTCGGTGCTCGCGCAGAAGGAACGCGAACTGGTATTTCGCATCGAGCCGGGCAACGCGTCCTGGTTCAGCG
GCCTGCCCCGCGGCGTCGAAGAACTGCAGCTGACGCACTCGACCTTCGGCAACCAGCAGAACATCCACGCCTGGTGGTGG
CCGGCGGCCGATGCCGATGCTCCCGCGCTGCTCTACCTGCACGGTGTGCGCTGGAACCTCACCGGCCATCTGTTCCGTCT
CGAGCAGCTGCGCAACCTGGGGTTCTCGGTGCTGGCCATCGACTACCGCGGCTTCGGCCAGAGCCTGGGCGAGCTGCCAT
CCGAACGCAGTGTCTACGCCGACGCACGGGTCGGCTGGGAACGTCTGAAGGCGCTGCAACCGGACCCGGACAAACGCTTC
ATCTACGGCCACTCCCTTGGCGGCGCGGTGGCCGTGGACCTCGCTGCCGAGCTTGGCGAACAGGCCGAGCGCGGCGACAG
CCCGCCGCAAGCGCGGGCGCTGATCATCGAATCGACCTTCACCTCGCTGGCCGACGTGGCGACGGTGGTTTCCGACACCA
CGCTGCCGGTGCGCTGGCTGCTGTCGCAGAAATTCGACTCGATCGACAAGATCGACCGCATCGGCATGCCGCTGCTGGTG
GTACACGGCACCGATGACCGCTACGTGCCGGCACGCTTCAGCGAACAGCTCTACCAAGCCGCACGCCCGCCCAAGGAGCT
GCTGCTGGTGGAGGGCGCCACGCACAACAACAGCCTGCGCGTAGCACCCAGCGCCTACGCCAGGGCACTGCAGGCGTTGC
TCAAGTCCGCCAGTCAGCCGTCGGTGGAGATCTCCAGCCGCGATTAG

Upstream 100 bases:

>100_bases
GCGCGCAACATGCAGTAATCAGTGCTGCGACGACCCGTCTTGCAGATCGTCCGGCAAGCGGGTCCCATCTATGGCTTTCT
GATCGTCGAGGTGAACGCCC

Downstream 100 bases:

>100_bases
ATTCGGCAGCAATACGCTGCTGACTATCGATAAGTGATGTAGAGTTCGCACACATTTACGTGAGAGCTCTACAGTGGCTC
ATTGGCTCTGTTTGATATTG

Product: alpha/beta fold family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MQRFFLFRSKARRLCLLLVAMIAVGLPVGCSVLAQKERELVFRIEPGNASWFSGLPRGVEELQLTHSTFGNQQNIHAWWW
PAADADAPALLYLHGVRWNLTGHLFRLEQLRNLGFSVLAIDYRGFGQSLGELPSERSVYADARVGWERLKALQPDPDKRF
IYGHSLGGAVAVDLAAELGEQAERGDSPPQARALIIESTFTSLADVATVVSDTTLPVRWLLSQKFDSIDKIDRIGMPLLV
VHGTDDRYVPARFSEQLYQAARPPKELLLVEGATHNNSLRVAPSAYARALQALLKSASQPSVEISSRD

Sequences:

>Translated_308_residues
MQRFFLFRSKARRLCLLLVAMIAVGLPVGCSVLAQKERELVFRIEPGNASWFSGLPRGVEELQLTHSTFGNQQNIHAWWW
PAADADAPALLYLHGVRWNLTGHLFRLEQLRNLGFSVLAIDYRGFGQSLGELPSERSVYADARVGWERLKALQPDPDKRF
IYGHSLGGAVAVDLAAELGEQAERGDSPPQARALIIESTFTSLADVATVVSDTTLPVRWLLSQKFDSIDKIDRIGMPLLV
VHGTDDRYVPARFSEQLYQAARPPKELLLVEGATHNNSLRVAPSAYARALQALLKSASQPSVEISSRD
>Mature_308_residues
MQRFFLFRSKARRLCLLLVAMIAVGLPVGCSVLAQKERELVFRIEPGNASWFSGLPRGVEELQLTHSTFGNQQNIHAWWW
PAADADAPALLYLHGVRWNLTGHLFRLEQLRNLGFSVLAIDYRGFGQSLGELPSERSVYADARVGWERLKALQPDPDKRF
IYGHSLGGAVAVDLAAELGEQAERGDSPPQARALIIESTFTSLADVATVVSDTTLPVRWLLSQKFDSIDKIDRIGMPLLV
VHGTDDRYVPARFSEQLYQAARPPKELLLVEGATHNNSLRVAPSAYARALQALLKSASQPSVEISSRD

Specific function: Unknown

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To S.pombe bem46 and yeast YNL320w [H]

Homologues:

Organism=Homo sapiens, GI109689718, Length=210, Percent_Identity=33.3333333333333, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI24308097, Length=210, Percent_Identity=33.3333333333333, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI49355781, Length=218, Percent_Identity=33.0275229357798, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI71051602, Length=260, Percent_Identity=29.2307692307692, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI71051600, Length=259, Percent_Identity=29.3436293436293, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI32451492, Length=245, Percent_Identity=30.2040816326531, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI32528310, Length=245, Percent_Identity=30.2040816326531, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI151301175, Length=194, Percent_Identity=32.9896907216495, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI194306562, Length=166, Percent_Identity=32.5301204819277, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI194306564, Length=166, Percent_Identity=32.5301204819277, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI226510965, Length=207, Percent_Identity=29.4685990338164, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71988362, Length=194, Percent_Identity=35.0515463917526, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17532877, Length=161, Percent_Identity=32.2981366459627, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71985392, Length=199, Percent_Identity=28.1407035175879, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71985387, Length=201, Percent_Identity=26.865671641791, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI17137566, Length=237, Percent_Identity=30.379746835443, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI281362521, Length=203, Percent_Identity=30.0492610837438, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI281362519, Length=203, Percent_Identity=30.0492610837438, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI28571878, Length=203, Percent_Identity=30.0492610837438, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24655464, Length=191, Percent_Identity=30.8900523560209, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24655467, Length=191, Percent_Identity=30.8900523560209, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002925 [H]

Pfam domain/function: PF01738 DLH [H]

EC number: NA

Molecular weight: Translated: 34169; Mature: 34169

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRFFLFRSKARRLCLLLVAMIAVGLPVGCSVLAQKERELVFRIEPGNASWFSGLPRGVE
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEECCCCCHHHCCCCCCHH
ELQLTHSTFGNQQNIHAWWWPAADADAPALLYLHGVRWNLTGHLFRLEQLRNLGFSVLAI
HHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEEECEEECCCHHHHHHHHHHHCCCEEEEE
DYRGFGQSLGELPSERSVYADARVGWERLKALQPDPDKRFIYGHSLGGAVAVDLAAELGE
ECCHHHHHHHCCCCCCCEEHHHHHCHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHH
QAERGDSPPQARALIIESTFTSLADVATVVSDTTLPVRWLLSQKFDSIDKIDRIGMPLLV
HHHCCCCCCHHEEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEE
VHGTDDRYVPARFSEQLYQAARPPKELLLVEGATHNNSLRVAPSAYARALQALLKSASQP
EECCCCCEECHHHHHHHHHHHCCCHHEEEEECCCCCCCEEECHHHHHHHHHHHHHCCCCC
SVEISSRD
CEEECCCC
>Mature Secondary Structure
MQRFFLFRSKARRLCLLLVAMIAVGLPVGCSVLAQKERELVFRIEPGNASWFSGLPRGVE
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEECCCCCHHHCCCCCCHH
ELQLTHSTFGNQQNIHAWWWPAADADAPALLYLHGVRWNLTGHLFRLEQLRNLGFSVLAI
HHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEEECEEECCCHHHHHHHHHHHCCCEEEEE
DYRGFGQSLGELPSERSVYADARVGWERLKALQPDPDKRFIYGHSLGGAVAVDLAAELGE
ECCHHHHHHHCCCCCCCEEHHHHHCHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHH
QAERGDSPPQARALIIESTFTSLADVATVVSDTTLPVRWLLSQKFDSIDKIDRIGMPLLV
HHHCCCCCCHHEEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEE
VHGTDDRYVPARFSEQLYQAARPPKELLLVEGATHNNSLRVAPSAYARALQALLKSASQP
EECCCCCEECHHHHHHHHHHHCCCHHEEEEECCCCCCCEEECHHHHHHHHHHHHHCCCCC
SVEISSRD
CEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]