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The map label for this gene is zraS [C]

Identifier: 146283217

GI number: 146283217

Start: 3100582

End: 3102669

Strand: Direct

Name: zraS [C]

Synonym: PST_2882

Alternate gene names: 146283217

Gene position: 3100582-3102669 (Clockwise)

Preceding gene: 146283206

Following gene: 146283220

Centisome position: 67.88

GC content: 67.19

Gene sequence:

>2088_bases
ATGGCAGGCGAAACTGCGGAAGCAAAGCGAATCGTTCTCGGCATGCGCGACAGCGACAAACGGCGCGAGCTCTCCGCGCT
GCTGGCCGCCGAGGGCTACAGCGTCGGCCTTTGCACTGACCAGACGAGCCTGGCACAGCGCATCGACGAGACGGTCGACG
TCGTGTTGCTCGCCGACGAGCTGGCGGCGGGGCCGTTGGATAACCTCAGCGCCGCGCTCGGGCAACTGCCGGCCGGCGGA
GCCATTCCGTTCATCCTGCTGGACTCCGGCACCGAGCCCCATGCTGTGCTCCGTGCCCGCCTGCCGTCGGCGATCAGCGA
CTTCGTGGTACTCGAAGAACCGGTCGGGCCCGCCACGCTGCTCAGCTGCCTCGCCACCTGCATACAGCTGCATCGGGAGC
GGCTCGCCCGGCAGCGACAGAAGTCCGCACAAGTCGATGAGCGAGCCCGCTTCGAGCGACTGATCGAGAACCTTCCAGTC
GGGGTCTGCTTCATCGATACCGACGGCAATACGCTGCTCAGCAACCCCAAGTACGACGAGTACGTGCCGAACCGGAAGAT
ACCTTCGGCGGCGCCCGACCGGGCCCGGCGCTGGGTAGGCCTGGACAGCCAGGGGCAGGTCATACCGCCGAGCCAGTACG
TCGGTGCCCGTGCCCTGCGCGGCGAGCAGGTAAATGACCAGGACTACCGGTACTACCCCGAAAACGGCGGCGAACGCTGG
CTGCGCCTGAGCGGCGTGCCCCTCTATGACAACACCGAGCAGCCGATGGGCGCGGCGGTAGTGATCATCGACGTCGATGC
CGAGAGGCGCAGCGAGGAGATGCTGCGCGAGTTCAATCAGCAGCTCGAGCAGGAGGTCGAGCTGCGAACCCAGGCACTGC
AGCAGGCGCTCGACCAACTGACCGTCGAAGTCCAGGAGCGCAGCCGAGCAGAGGAACAACTGCGCCACTCTCAGAAGATG
GACGCCGTCGGCCAGCTTACCGGCGGCATCGCACACGACTTCAACAACATGCTGACTGGCATCATCGGTGCGCTGGATCT
GATTCGCCTGCGCCTGGATACCGGTCGCCATGACGACCTGCCGCGGTATCTCGACGCGGCACATGGCTCGGCGCAGCGCG
CCGCCTCCCTGACCCAGCGCCTGCTGGCCTTCTCCCGCCGCCAGCCTTTGCAGACCCGGCCGACCGCGGTCAATCCGCTG
ATCCGCTCGCTTGCCGAGCTGTTGCAGCGCAGCCTGGGCGAAACCATCCGCTTCGAGCTGGCCATCGACGAGGCCGCCGG
GCTCGCCCTGGTCGACCCCAGCCAGATGGAAAACGCCCTGCTCAACCTGACGTTCAACGCCCGGGATGCCATGCCGGACG
GCGGCACATTGCGCATCGAGACGCAGCACCTGGAATTGCCAGCGGAGCAGGCCTCCCGCCACGGCGTGCAGACCGGCGAA
TACCTGTGCGTGCGCGTCATCGACACCGGCATTGGCATTCCAGCGCCCCTGGTGGACAAGGTGTTCGAGCCTTTCTTCAC
GACCAAGCCCCTCGGCGAAGGTACCGGGCTCGGCTTGTCGATGGTCTACGGCTTCGTCCGCCAGAGCGGCGGCTTCATCA
CCATCGACAGCTGCCAGGGCAAGGGGACCCGCGTCGCCCTGCACATGCCAGCGGCGCCTGCCGACGCGCGGGAAGAATCG
GCCGCGGCAACGAGCCGCGTTCCCGGTGCAGGGGGCGGGCGCACGGTACTGTTGGTCGAGGACGACGATACCGTGCGGCC
GCTGCTGCAGAGCGCGCTCGAGGATTTCGGCTACCGTGTGCACCTGGCCGCCGACAGTCAGAGCGCCCTGGAAGTCGCCG
CACAGCTCGATTCGCTCGACCTGCTGCTGACCGATGTCGGCCTGCCGGGGCTCAACGGCCGCCAGCTCGCCGAAATGCTT
CAGCAACGGCGCCCTGGCCTGCCGGTGGTGCTGATCACCGGCTACGCCGAACAGGCCGCGACCCGCCTCGACTGCCTGGC
CCCCGGCATGCAACTCATGACCAAACCCTTCTCGCTCGAACTGCTGGCCGAAACCGTAGCCCGCGCAATCACCACCCCGG
TTGGCTGA

Upstream 100 bases:

>100_bases
CCTGCTTTCGCACTGCCCGACACCGGCAGCCGCGTCGAGCCATGTCCGATCGATCGGGAGCCCTGATCGGACCACCAACC
AGACAAGGCGCACGTTACAG

Downstream 100 bases:

>100_bases
GAGGCCCTACCACGGCAGCACTTCTGCGCTGTACGCATGGAACCCGCCACTCGCCTCGGGCCCCAGGCTGTCGATGACCC
TGAGCAGATCCCGCGCGGCA

Product: sensory box histidine kinase/response regulator

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 695; Mature: 694

Protein sequence:

>695_residues
MAGETAEAKRIVLGMRDSDKRRELSALLAAEGYSVGLCTDQTSLAQRIDETVDVVLLADELAAGPLDNLSAALGQLPAGG
AIPFILLDSGTEPHAVLRARLPSAISDFVVLEEPVGPATLLSCLATCIQLHRERLARQRQKSAQVDERARFERLIENLPV
GVCFIDTDGNTLLSNPKYDEYVPNRKIPSAAPDRARRWVGLDSQGQVIPPSQYVGARALRGEQVNDQDYRYYPENGGERW
LRLSGVPLYDNTEQPMGAAVVIIDVDAERRSEEMLREFNQQLEQEVELRTQALQQALDQLTVEVQERSRAEEQLRHSQKM
DAVGQLTGGIAHDFNNMLTGIIGALDLIRLRLDTGRHDDLPRYLDAAHGSAQRAASLTQRLLAFSRRQPLQTRPTAVNPL
IRSLAELLQRSLGETIRFELAIDEAAGLALVDPSQMENALLNLTFNARDAMPDGGTLRIETQHLELPAEQASRHGVQTGE
YLCVRVIDTGIGIPAPLVDKVFEPFFTTKPLGEGTGLGLSMVYGFVRQSGGFITIDSCQGKGTRVALHMPAAPADAREES
AAATSRVPGAGGGRTVLLVEDDDTVRPLLQSALEDFGYRVHLAADSQSALEVAAQLDSLDLLLTDVGLPGLNGRQLAEML
QQRRPGLPVVLITGYAEQAATRLDCLAPGMQLMTKPFSLELLAETVARAITTPVG

Sequences:

>Translated_695_residues
MAGETAEAKRIVLGMRDSDKRRELSALLAAEGYSVGLCTDQTSLAQRIDETVDVVLLADELAAGPLDNLSAALGQLPAGG
AIPFILLDSGTEPHAVLRARLPSAISDFVVLEEPVGPATLLSCLATCIQLHRERLARQRQKSAQVDERARFERLIENLPV
GVCFIDTDGNTLLSNPKYDEYVPNRKIPSAAPDRARRWVGLDSQGQVIPPSQYVGARALRGEQVNDQDYRYYPENGGERW
LRLSGVPLYDNTEQPMGAAVVIIDVDAERRSEEMLREFNQQLEQEVELRTQALQQALDQLTVEVQERSRAEEQLRHSQKM
DAVGQLTGGIAHDFNNMLTGIIGALDLIRLRLDTGRHDDLPRYLDAAHGSAQRAASLTQRLLAFSRRQPLQTRPTAVNPL
IRSLAELLQRSLGETIRFELAIDEAAGLALVDPSQMENALLNLTFNARDAMPDGGTLRIETQHLELPAEQASRHGVQTGE
YLCVRVIDTGIGIPAPLVDKVFEPFFTTKPLGEGTGLGLSMVYGFVRQSGGFITIDSCQGKGTRVALHMPAAPADAREES
AAATSRVPGAGGGRTVLLVEDDDTVRPLLQSALEDFGYRVHLAADSQSALEVAAQLDSLDLLLTDVGLPGLNGRQLAEML
QQRRPGLPVVLITGYAEQAATRLDCLAPGMQLMTKPFSLELLAETVARAITTPVG
>Mature_694_residues
AGETAEAKRIVLGMRDSDKRRELSALLAAEGYSVGLCTDQTSLAQRIDETVDVVLLADELAAGPLDNLSAALGQLPAGGA
IPFILLDSGTEPHAVLRARLPSAISDFVVLEEPVGPATLLSCLATCIQLHRERLARQRQKSAQVDERARFERLIENLPVG
VCFIDTDGNTLLSNPKYDEYVPNRKIPSAAPDRARRWVGLDSQGQVIPPSQYVGARALRGEQVNDQDYRYYPENGGERWL
RLSGVPLYDNTEQPMGAAVVIIDVDAERRSEEMLREFNQQLEQEVELRTQALQQALDQLTVEVQERSRAEEQLRHSQKMD
AVGQLTGGIAHDFNNMLTGIIGALDLIRLRLDTGRHDDLPRYLDAAHGSAQRAASLTQRLLAFSRRQPLQTRPTAVNPLI
RSLAELLQRSLGETIRFELAIDEAAGLALVDPSQMENALLNLTFNARDAMPDGGTLRIETQHLELPAEQASRHGVQTGEY
LCVRVIDTGIGIPAPLVDKVFEPFFTTKPLGEGTGLGLSMVYGFVRQSGGFITIDSCQGKGTRVALHMPAAPADAREESA
AATSRVPGAGGGRTVLLVEDDDTVRPLLQSALEDFGYRVHLAADSQSALEVAAQLDSLDLLLTDVGLPGLNGRQLAEMLQ
QRRPGLPVVLITGYAEQAATRLDCLAPGMQLMTKPFSLELLAETVARAITTPVG

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=248, Percent_Identity=27.8225806451613, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI48994928, Length=409, Percent_Identity=26.161369193154, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1788549, Length=249, Percent_Identity=28.9156626506024, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI145693157, Length=509, Percent_Identity=24.3614931237721, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87081816, Length=450, Percent_Identity=25.3333333333333, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1790300, Length=248, Percent_Identity=30.6451612903226, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1788713, Length=266, Percent_Identity=26.3157894736842, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 75563; Mature: 75432

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGETAEAKRIVLGMRDSDKRRELSALLAAEGYSVGLCTDQTSLAQRIDETVDVVLLADE
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHEEEEEEHH
LAAGPLDNLSAALGQLPAGGAIPFILLDSGTEPHAVLRARLPSAISDFVVLEEPVGPATL
HCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCEEEECCCCHHHH
LSCLATCIQLHRERLARQRQKSAQVDERARFERLIENLPVGVCFIDTDGNTLLSNPKYDE
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEECCCCEEECCCCCHH
YVPNRKIPSAAPDRARRWVGLDSQGQVIPPSQYVGARALRGEQVNDQDYRYYPENGGERW
CCCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHCHHHHCCCCCCCCCCEECCCCCCCCE
LRLSGVPLYDNTEQPMGAAVVIIDVDAERRSEEMLREFNQQLEQEVELRTQALQQALDQL
EEECCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVEVQERSRAEEQLRHSQKMDAVGQLTGGIAHDFNNMLTGIIGALDLIRLRLDTGRHDDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PRYLDAAHGSAQRAASLTQRLLAFSRRQPLQTRPTAVNPLIRSLAELLQRSLGETIRFEL
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEE
AIDEAAGLALVDPSQMENALLNLTFNARDAMPDGGTLRIETQHLELPAEQASRHGVQTGE
EEECCCCEEEECHHHHCCCCEEEEECCCCCCCCCCEEEEEEHHCCCCHHHHHHCCCCCCC
YLCVRVIDTGIGIPAPLVDKVFEPFFTTKPLGEGTGLGLSMVYGFVRQSGGFITIDSCQG
EEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCC
KGTRVALHMPAAPADAREESAAATSRVPGAGGGRTVLLVEDDDTVRPLLQSALEDFGYRV
CCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEE
HLAADSQSALEVAAQLDSLDLLLTDVGLPGLNGRQLAEMLQQRRPGLPVVLITGYAEQAA
EEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEECCHHHHH
TRLDCLAPGMQLMTKPFSLELLAETVARAITTPVG
HHHHHHCCCHHHHCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AGETAEAKRIVLGMRDSDKRRELSALLAAEGYSVGLCTDQTSLAQRIDETVDVVLLADE
CCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHEEEEEEHH
LAAGPLDNLSAALGQLPAGGAIPFILLDSGTEPHAVLRARLPSAISDFVVLEEPVGPATL
HCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCEEEECCCCHHHH
LSCLATCIQLHRERLARQRQKSAQVDERARFERLIENLPVGVCFIDTDGNTLLSNPKYDE
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEECCCCEEECCCCCHH
YVPNRKIPSAAPDRARRWVGLDSQGQVIPPSQYVGARALRGEQVNDQDYRYYPENGGERW
CCCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHCHHHHCCCCCCCCCCEECCCCCCCCE
LRLSGVPLYDNTEQPMGAAVVIIDVDAERRSEEMLREFNQQLEQEVELRTQALQQALDQL
EEECCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVEVQERSRAEEQLRHSQKMDAVGQLTGGIAHDFNNMLTGIIGALDLIRLRLDTGRHDDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PRYLDAAHGSAQRAASLTQRLLAFSRRQPLQTRPTAVNPLIRSLAELLQRSLGETIRFEL
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEE
AIDEAAGLALVDPSQMENALLNLTFNARDAMPDGGTLRIETQHLELPAEQASRHGVQTGE
EEECCCCEEEECHHHHCCCCEEEEECCCCCCCCCCEEEEEEHHCCCCHHHHHHCCCCCCC
YLCVRVIDTGIGIPAPLVDKVFEPFFTTKPLGEGTGLGLSMVYGFVRQSGGFITIDSCQG
EEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCC
KGTRVALHMPAAPADAREESAAATSRVPGAGGGRTVLLVEDDDTVRPLLQSALEDFGYRV
CCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEE
HLAADSQSALEVAAQLDSLDLLLTDVGLPGLNGRQLAEMLQQRRPGLPVVLITGYAEQAA
EEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEECCHHHHH
TRLDCLAPGMQLMTKPFSLELLAETVARAITTPVG
HHHHHHCCCHHHHCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA